| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J D Elsworth, J R Taylor, P Berger, R H Rot. Cocaine-sensitive and -insensitive dopamine uptake in prefrontal cortex, nucleus accumbens and striatum. Neurochemistry international. vol 23. issue 1. 1993-10-08. PMID:8369733. |
the occurrence of cocaine-sensitive dopamine uptake in all examined regions and its equal sensitivity to cocaine and gbr 12909 is consistent with the involvement of nucleus accumbens and/or prefrontal cortex in the reinforcing effects of cocaine. |
1993-10-08 |
2023-08-12 |
Not clear |
| P Robledo, G F Koo. Two discrete nucleus accumbens projection areas differentially mediate cocaine self-administration in the rat. Behavioural brain research. vol 55. issue 2. 1993-09-30. PMID:8395179. |
two discrete nucleus accumbens projection areas differentially mediate cocaine self-administration in the rat. |
1993-09-30 |
2023-08-12 |
human |
| P Robledo, G F Koo. Two discrete nucleus accumbens projection areas differentially mediate cocaine self-administration in the rat. Behavioural brain research. vol 55. issue 2. 1993-09-30. PMID:8395179. |
the region of the nucleus accumbens and its connections have been implicated in the reinforcing actions of cocaine as measured by intravenous self-administration. |
1993-09-30 |
2023-08-12 |
human |
| P Robledo, G F Koo. Two discrete nucleus accumbens projection areas differentially mediate cocaine self-administration in the rat. Behavioural brain research. vol 55. issue 2. 1993-09-30. PMID:8395179. |
in the present study, the importance of another nucleus accumbens output, the subcommissural ventral pallidum (svp), in mediating the self-administration of cocaine in the rat was explored. |
1993-09-30 |
2023-08-12 |
human |
| F J White, X T Hu, D J Henr. Electrophysiological effects of cocaine in the rat nucleus accumbens: microiontophoretic studies. The Journal of pharmacology and experimental therapeutics. vol 266. issue 2. 1993-09-17. PMID:8355182. |
electrophysiological effects of cocaine in the rat nucleus accumbens: microiontophoretic studies. |
1993-09-17 |
2023-08-12 |
rat |
| F J White, X T Hu, D J Henr. Electrophysiological effects of cocaine in the rat nucleus accumbens: microiontophoretic studies. The Journal of pharmacology and experimental therapeutics. vol 266. issue 2. 1993-09-17. PMID:8355182. |
the nucleus accumbens (nac) is intricately involved in maintaining cocaine self-administration. |
1993-09-17 |
2023-08-12 |
rat |
| B A Sorg, S Y Chen, P W Kaliva. Time course of tyrosine hydroxylase expression after behavioral sensitization to cocaine. The Journal of pharmacology and experimental therapeutics. vol 266. issue 1. 1993-08-19. PMID:8101222. |
levels of tyrosine hydroxylase (th) immunoreactivity and mrna in the ventral tegmental area (vta) and th immunoreactivity in the nucleus accumbens were measured after early (24 hr) and late (3 weeks) withdrawal times from acute and repeated cocaine treatment. |
1993-08-19 |
2023-08-12 |
Not clear |
| M Heilig, J A Engel, B Söderpal. C-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine. European journal of pharmacology. vol 236. issue 2. 1993-08-05. PMID:8319761. |
c-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine. |
1993-08-05 |
2023-08-12 |
rat |
| M Heilig, J A Engel, B Söderpal. C-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine. European journal of pharmacology. vol 236. issue 2. 1993-08-05. PMID:8319761. |
here, we report that bilateral administration of an antisense oligo against c-fos in the nucleus accumbens blocks cocaine induced locomotor stimulation, without affecting spontaneous exploratory activity. |
1993-08-05 |
2023-08-12 |
rat |
| D D Wheeler, A M Edwards, J G Ond. Dopamine uptake in five structures of the brain: comparison of rate, sodium dependence and sensitivity to cocaine. Neuropharmacology. vol 32. issue 5. 1993-08-03. PMID:8321431. |
neither the rate of uptake nor the na-dependence correlated precisely with the sensitivity to cocaine but the two structures which showed the greatest rate of uptake (nucleus accumbens and striatum) also showed the greatest sensitivity to [na]o. |
1993-08-03 |
2023-08-12 |
rat |
| T Baptista, S R Weiss, R M Pos. Carbamazepine attenuates cocaine-induced increases in dopamine in the nucleus accumbens: an in vivo dialysis study. European journal of pharmacology. vol 236. issue 1. 1993-07-30. PMID:8319744. |
the basal levels of dopamine in the nucleus accumbens did not differ between groups; however, the increases in dopamine following cocaine administration (4 mg/kg i.v.) |
1993-07-30 |
2023-08-12 |
rat |
| X Guitart, J H Kogan, M Berhow, R Z Terwilliger, G K Aghajanian, E J Nestle. Lewis and Fischer rat strains display differences in biochemical, electrophysiological and behavioral parameters: studies in the nucleus accumbens and locus coeruleus of drug naive and morphine-treated animals. Brain research. vol 611. issue 1. 1993-07-29. PMID:8518951. |
in the current study, we compared lewis and fischer rats with respect to levels of adenylate cyclase, cyclic amp-dependent protein kinase and g-proteins in the nucleus accumbens (nac) and locus coeruleus (lc), brain regions in sprague-dawley rats where these proteins are regulated by chronic exposure to morphine or to cocaine. |
1993-07-29 |
2023-08-12 |
rat |
| W A Cass, G A Gerhardt, K Gillespie, P Curella, R D Mayfield, N R Zahnise. Reduced clearance of exogenous dopamine in rat nucleus accumbens, but not in dorsal striatum, following cocaine challenge in rats withdrawn from repeated cocaine administration. Journal of neurochemistry. vol 61. issue 1. 1993-07-22. PMID:8515274. |
the decrease in dopamine clearance rate observed in the nucleus accumbens of the cocaine-treated rats after a challenge injection of cocaine is consistent with increased dopaminergic transmission, but does not appear to be sufficient in itself for producing behavioral sensitization. |
1993-07-22 |
2023-08-12 |
rat |
| W A Cass, N R Zahnise. Cocaine levels in striatum and nucleus accumbens: augmentation following challenge injection in rats withdrawn from repeated cocaine administration. Neuroscience letters. vol 152. issue 1-2. 1993-07-19. PMID:8515873. |
cocaine levels in striatum and nucleus accumbens: augmentation following challenge injection in rats withdrawn from repeated cocaine administration. |
1993-07-19 |
2023-08-12 |
rat |
| W A Cass, N R Zahnise. Cocaine levels in striatum and nucleus accumbens: augmentation following challenge injection in rats withdrawn from repeated cocaine administration. Neuroscience letters. vol 152. issue 1-2. 1993-07-19. PMID:8515873. |
), and levels of cocaine were measured in dorsal striatum and nucleus accumbens 20 min after the last injection. |
1993-07-19 |
2023-08-12 |
rat |
| R Maldonado, P Robledo, A J Chover, S B Caine, G F Koo. D1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat. Pharmacology, biochemistry, and behavior. vol 45. issue 1. 1993-07-19. PMID:8516365. |
d1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat. |
1993-07-19 |
2023-08-12 |
rat |
| R Maldonado, P Robledo, A J Chover, S B Caine, G F Koo. D1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat. Pharmacology, biochemistry, and behavior. vol 45. issue 1. 1993-07-19. PMID:8516365. |
sch23390, a selective d1 dopamine antagonist, significantly increased the self-administration of cocaine when injected into the nucleus accumbens. |
1993-07-19 |
2023-08-12 |
rat |
| R Maldonado, P Robledo, A J Chover, S B Caine, G F Koo. D1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat. Pharmacology, biochemistry, and behavior. vol 45. issue 1. 1993-07-19. PMID:8516365. |
these data suggest that d1 receptors in the nucleus accumbens are important for the reinforcing properties of cocaine. |
1993-07-19 |
2023-08-12 |
rat |
| C D Striplin, P W Kaliva. Robustness of G protein changes in cocaine sensitization shown with immunoblotting. Synapse (New York, N.Y.). vol 14. issue 1. 1993-07-15. PMID:8511715. |
a significant decline in gi1 alpha was seen in the nucleus accumbens at 14 days following daily cocaine administration regardless of whether they received an acute challenge with cocaine or saline 1 hr prior to decapitation. |
1993-07-15 |
2023-08-12 |
rat |
| C D Striplin, P W Kaliva. Robustness of G protein changes in cocaine sensitization shown with immunoblotting. Synapse (New York, N.Y.). vol 14. issue 1. 1993-07-15. PMID:8511715. |
no change in g protein immunoreactivity was measured in the nucleus accumbens or ventral tegmental area of rats decapitated 1 hr after discontinuing daily cocaine. |
1993-07-15 |
2023-08-12 |
rat |