| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Y Chang, S F Sawyer, R S Lee, D J Woodwar. Electrophysiological and pharmacological evidence for the role of the nucleus accumbens in cocaine self-administration in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 3 Pt 1. 1994-04-07. PMID:8120621. |
the goal of this study was to clarify the role of the nucleus accumbens septi (nas) in the expression of cocaine self-administration behaviors. |
1994-04-07 |
2023-08-12 |
rat |
| E M Unterwald, B M Cox, M J Kreek, T E Cote, S Izenwasse. Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity. Synapse (New York, N.Y.). vol 15. issue 1. 1994-03-17. PMID:8310423. |
repeated daily cocaine injections have been shown to alter mu-opioid receptor densities in the caudate putamen and nucleus accumbens of rat brain (unterwald et al., 1991, 1992). |
1994-03-17 |
2023-08-12 |
rat |
| E M Unterwald, B M Cox, M J Kreek, T E Cote, S Izenwasse. Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity. Synapse (New York, N.Y.). vol 15. issue 1. 1994-03-17. PMID:8310423. |
adenylyl cyclase activity was measured in rat rostral caudate putamen and nucleus accumbens following repeated cocaine administration to determine the functional consequences of cocaine-induced opioid receptor changes. |
1994-03-17 |
2023-08-12 |
rat |
| E M Unterwald, B M Cox, M J Kreek, T E Cote, S Izenwasse. Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity. Synapse (New York, N.Y.). vol 15. issue 1. 1994-03-17. PMID:8310423. |
basal adenylyl cyclase activity was unchanged in the nucleus accumbens following cocaine treatment. |
1994-03-17 |
2023-08-12 |
rat |
| E M Unterwald, B M Cox, M J Kreek, T E Cote, S Izenwasse. Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity. Synapse (New York, N.Y.). vol 15. issue 1. 1994-03-17. PMID:8310423. |
these results suggest that chronic, repeated cocaine administration results in a selective impairment of delta-opioid receptor-mediated effector function in the caudate putamen and nucleus accumbens. |
1994-03-17 |
2023-08-12 |
rat |
| J K Staley, M Basile, D D Flynn, D C Mas. Visualizing dopamine and serotonin transporters in the human brain with the potent cocaine analogue [125I]RTI-55: in vitro binding and autoradiographic characterization. Journal of neurochemistry. vol 62. issue 2. 1994-03-02. PMID:8294917. |
autoradiographic mapping of [125i]rti-55 revealed very high densities of cocaine recognition sites over areas known to be rich in dopaminergic innervation, including the caudate, putamen, and nucleus accumbens. |
1994-03-02 |
2023-08-12 |
human |
| D J Fontana, R M Post, A Per. Conditioned increases in mesolimbic dopamine overflow by stimuli associated with cocaine. Brain research. vol 629. issue 1. 1994-02-23. PMID:8287278. |
environmental stimuli paired with a large dose of cocaine for one training session elicited significant increases in locomotor activity and in extracellular dopamine in the nucleus accumbens of rats during a second test session with a low dose of cocaine. |
1994-02-23 |
2023-08-12 |
rat |
| R M Carelli, V C King, R E Hampson, S A Deadwyle. Firing patterns of nucleus accumbens neurons during cocaine self-administration in rats. Brain research. vol 626. issue 1-2. 1994-02-14. PMID:8281424. |
firing patterns of nucleus accumbens neurons during cocaine self-administration in rats. |
1994-02-14 |
2023-08-12 |
rat |
| R M Carelli, V C King, R E Hampson, S A Deadwyle. Firing patterns of nucleus accumbens neurons during cocaine self-administration in rats. Brain research. vol 626. issue 1-2. 1994-02-14. PMID:8281424. |
the firing patterns of neurons in the nucleus accumbens (na) were recorded in rats trained to self-administer cocaine via response contingent intravenous drug infusions. |
1994-02-14 |
2023-08-12 |
rat |
| F G Kaddis, L J Wallace, N J Uretsk. AMPA/kainate antagonists in the nucleus accumbens inhibit locomotor stimulatory response to cocaine and dopamine agonists. Pharmacology, biochemistry, and behavior. vol 46. issue 3. 1994-02-09. PMID:7506423. |
ampa/kainate antagonists in the nucleus accumbens inhibit locomotor stimulatory response to cocaine and dopamine agonists. |
1994-02-09 |
2023-08-12 |
Not clear |
| F G Kaddis, L J Wallace, N J Uretsk. AMPA/kainate antagonists in the nucleus accumbens inhibit locomotor stimulatory response to cocaine and dopamine agonists. Pharmacology, biochemistry, and behavior. vol 46. issue 3. 1994-02-09. PMID:7506423. |
the purpose of this study was to determine whether ampa/kainate excitatory amino acid receptors in the nucleus accumbens (nac) play a role in the locomotor stimulation produced by cocaine and dopamine receptor agonists. |
1994-02-09 |
2023-08-12 |
Not clear |
| P A Broderick, E P Kornak, F Eng, R Wechsle. Real time detection of acute (IP) cocaine-enhanced dopamine and serotonin release in ventrolateral nucleus accumbens of the behaving Norway rat. Pharmacology, biochemistry, and behavior. vol 46. issue 3. 1994-02-09. PMID:8278450. |
cocaine (10 mg/kg), administered intraperitoneal (ip), was studied for its effects on dopamine (da) and serotonin (5-ht) release in ventrolateral nucleus accumbens (vlnacc) of conscious and behaving male, virus-free, sprague-dawley rats with in vivo electrochemistry (voltammetry). |
1994-02-09 |
2023-08-12 |
rat |
| E A Kiyatki. Cocaine enhances the changes in extracellular dopamine in nucleus accumbens associated with reinforcing stimuli: a high-speed chronoamperometric study in freely moving rats. The European journal of neuroscience. vol 5. issue 3. 1994-01-27. PMID:8261108. |
cocaine enhances the changes in extracellular dopamine in nucleus accumbens associated with reinforcing stimuli: a high-speed chronoamperometric study in freely moving rats. |
1994-01-27 |
2023-08-12 |
rat |
| E A Kiyatki. Cocaine enhances the changes in extracellular dopamine in nucleus accumbens associated with reinforcing stimuli: a high-speed chronoamperometric study in freely moving rats. The European journal of neuroscience. vol 5. issue 3. 1994-01-27. PMID:8261108. |
on extracellular da in the nucleus accumbens and to assess the effects of cocaine on the response evoked by the presentation of tail-pinch and palatable food. |
1994-01-27 |
2023-08-12 |
rat |
| N H Chen, M E Reit. Dopamine and serotonin release-regulating autoreceptor sensitivity in A9/A10 cell body and terminal areas after withdrawal of rats from continuous infusion of cocaine. The Journal of pharmacology and experimental therapeutics. vol 267. issue 3. 1994-01-27. PMID:8263807. |
the effects of dopamine (da) and 5-hydroxytryptamine (5-ht) autoreceptor agents on electrically induced [3h]da and [3h]5-ht release from superfused slices of striatum, nucleus accumbens and ventral mesencephalon (vm) containing a9 and a10 neurons were investigated in rats made tolerant to the stimulatory effect of cocaine on locomotor behavior by a 14-day continuous infusion of cocaine (29 mg/kg/day) by s.c. implanted osmotic minipumps followed by a 7-day drug-free period. |
1994-01-27 |
2023-08-12 |
rat |
| A McGregor, D C Robert. Dopaminergic antagonism within the nucleus accumbens or the amygdala produces differential effects on intravenous cocaine self-administration under fixed and progressive ratio schedules of reinforcement. Brain research. vol 624. issue 1-2. 1994-01-13. PMID:8252397. |
dopaminergic antagonism within the nucleus accumbens or the amygdala produces differential effects on intravenous cocaine self-administration under fixed and progressive ratio schedules of reinforcement. |
1994-01-13 |
2023-08-12 |
Not clear |
| P Robledo, R Maldonado, G F Koo. Neurotensin injected into the nucleus accumbens blocks the psychostimulant effects of cocaine but does not attenuate cocaine self-administration in the rat. Brain research. vol 622. issue 1-2. 1994-01-06. PMID:8242350. |
neurotensin injected into the nucleus accumbens blocks the psychostimulant effects of cocaine but does not attenuate cocaine self-administration in the rat. |
1994-01-06 |
2023-08-12 |
rat |
| P Robledo, R Maldonado, G F Koo. Neurotensin injected into the nucleus accumbens blocks the psychostimulant effects of cocaine but does not attenuate cocaine self-administration in the rat. Brain research. vol 622. issue 1-2. 1994-01-06. PMID:8242350. |
in the present study, the hypothesis that neurotensin injected into the nucleus accumbens might modulate the psychostimulant and reinforcing actions of cocaine was tested. |
1994-01-06 |
2023-08-12 |
rat |
| P Robledo, R Maldonado, G F Koo. Neurotensin injected into the nucleus accumbens blocks the psychostimulant effects of cocaine but does not attenuate cocaine self-administration in the rat. Brain research. vol 622. issue 1-2. 1994-01-06. PMID:8242350. |
however, in experiment 2, neurotensin at doses of 4.2 and 16.7 micrograms injected into the nucleus accumbens significantly reduced the locomotor activation induced by an acute injection of cocaine (15 mg/kg i.p.) |
1994-01-06 |
2023-08-12 |
rat |
| P Robledo, R Maldonado, G F Koo. Neurotensin injected into the nucleus accumbens blocks the psychostimulant effects of cocaine but does not attenuate cocaine self-administration in the rat. Brain research. vol 622. issue 1-2. 1994-01-06. PMID:8242350. |
thus, neurotensin in the nucleus accumbens appears to specifically modulate the acute locomotor activating properties of cocaine but not cocaine self-administration. |
1994-01-06 |
2023-08-12 |
rat |