| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Pecins-Thompson, J Peri. Behavioral and neurochemical changes caused by repeated ethanol and cocaine administration. Psychopharmacology. vol 110. issue 4. 1995-03-29. PMID:7870915. |
in support of enhanced sensitization to cocaine, amphetamine-stimulated 3h-dopamine (da) release in striatum and d2 da receptor binding in the nucleus accumbens (nac) were increased in group ce compared to group c. in support of a loss of ethanol tolerance, increases in striatal d2 da and 35s-tbps binding seen in group e (which exhibited ethanol tolerance) were absent in group ce (which did not exhibit tolerance). |
1995-03-29 |
2023-08-12 |
rat |
| M S Hooks, G H Jones, S E Hemby, J B Justic. Environmental and pharmacological sensitization: effects of repeated administration of systemic or intra-nucleus accumbens cocaine. Psychopharmacology. vol 111. issue 1. 1995-03-29. PMID:7870925. |
in a second experiment, cocaine (100 micrograms/side) was infused into the nucleus accumbens (nacc) daily for 5 days. |
1995-03-29 |
2023-08-12 |
human |
| M E Benwell, D J Balfour, H M Lucch. Influence of tetrodotoxin and calcium on changes in extracellular dopamine levels evoked by systemic nicotine. Psychopharmacology. vol 112. issue 4. 1995-03-29. PMID:7871059. |
the influence of tetrodotoxin (ttx) and calcium on the increase of extracellular dopamine (da) levels in the nucleus accumbens (nacc), evoked by the systemic administration of nicotine, cocaine and d-amphetamine, have been studied in conscious, freely moving rats using in vivo microdialysis. |
1995-03-29 |
2023-08-12 |
rat |
| G H Jones, M S Hooks, J L Juncos, J B Justic. Effects of cocaine microinjections into the nucleus accumbens and medial prefrontal cortex on schedule-induced behaviour: comparison with systemic cocaine administration. Psychopharmacology. vol 115. issue 3. 1995-03-24. PMID:7871079. |
effects of cocaine microinjections into the nucleus accumbens and medial prefrontal cortex on schedule-induced behaviour: comparison with systemic cocaine administration. |
1995-03-24 |
2023-08-12 |
human |
| G H Jones, M S Hooks, J L Juncos, J B Justic. Effects of cocaine microinjections into the nucleus accumbens and medial prefrontal cortex on schedule-induced behaviour: comparison with systemic cocaine administration. Psychopharmacology. vol 115. issue 3. 1995-03-24. PMID:7871079. |
the effects of cocaine hcl infusions into either the nucleus accumbens (nacc) or medial prefrontal cortex (pfc) were compared on the performance of schedule-induced polydipsia (sip) and related behaviours. |
1995-03-24 |
2023-08-12 |
human |
| P M Callahan, R De La Garza, K A Cunningha. Discriminative stimulus properties of cocaine: modulation by dopamine D1 receptors in the nucleus accumbens. Psychopharmacology. vol 115. issue 1-2. 1995-03-20. PMID:7862881. |
discriminative stimulus properties of cocaine: modulation by dopamine d1 receptors in the nucleus accumbens. |
1995-03-20 |
2023-08-12 |
rat |
| P M Callahan, R De La Garza, K A Cunningha. Discriminative stimulus properties of cocaine: modulation by dopamine D1 receptors in the nucleus accumbens. Psychopharmacology. vol 115. issue 1-2. 1995-03-20. PMID:7862881. |
the purpose of the present study was to investigate the role of the nucleus accumbens and, in particular, accumbens da d1 receptors in modulating the stimulus effects of cocaine. |
1995-03-20 |
2023-08-12 |
rat |
| P M Callahan, R De La Garza, K A Cunningha. Discriminative stimulus properties of cocaine: modulation by dopamine D1 receptors in the nucleus accumbens. Psychopharmacology. vol 115. issue 1-2. 1995-03-20. PMID:7862881. |
microinjections of cocaine (2.5-40 micrograms) into the nucleus accumbens also engendered dose-dependent and complete substitutions (> 80% drug-lever responding) for the systemic training dose of cocaine, whereas intra-accumbens artificial cerebrospinal fluid (1 microliter/side) produced primarily saline-appropriate responding. |
1995-03-20 |
2023-08-12 |
rat |
| P M Callahan, R De La Garza, K A Cunningha. Discriminative stimulus properties of cocaine: modulation by dopamine D1 receptors in the nucleus accumbens. Psychopharmacology. vol 115. issue 1-2. 1995-03-20. PMID:7862881. |
the present results confirm the importance of the nucleus accumbens in mediating the discriminative stimulus properties of cocaine and suggest a primary role of accumbens da d1 receptors in modulating this behavior. |
1995-03-20 |
2023-08-12 |
rat |
| C A Heidbreder, T S Shippenber. U-69593 prevents cocaine sensitization by normalizing basal accumbens dopamine. Neuroreport. vol 5. issue 14. 1995-02-22. PMID:7827335. |
it is suggested that the responsiveness of mesolimbic da neurons to cocaine is intimately related to basal da concentrations within the acb and that u-69593, by normalizing cocaine-induced increases in basal da overflow, may prevent the development of behavioral sensitization to cocaine. |
1995-02-22 |
2023-08-12 |
Not clear |
| J R Walker, K A Sevarin. Regulation of cytochrome c oxidase subunit mRNA and enzyme activity in rat brain reward regions during withdrawal from chronic cocaine. Journal of neurochemistry. vol 64. issue 2. 1995-02-21. PMID:7830041. |
a subtractive hybridization and differential screening procedure was used to detect up-regulation of cytochrome c oxidase (co) subunits i, iii, and iv mrna in the nucleus accumbens (nac) of rats chronically treated with cocaine. |
1995-02-21 |
2023-08-12 |
rat |
| S D Glick, M E Kuehne, J Raucci, T E Wilson, D Larson, R W Keller, J N Carlso. Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum. Brain research. vol 657. issue 1-2. 1995-02-14. PMID:7820611. |
effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum. |
1995-02-14 |
2023-08-12 |
rat |
| W J Wieczorek, Z L Kru. A quantitative comparison on the effects of benztropine, cocaine and nomifensine on electrically evoked dopamine overflow and rate of re-uptake in the caudate putamen and nucleus accumbens in the rat brain slice. Brain research. vol 657. issue 1-2. 1995-02-14. PMID:7820642. |
a quantitative comparison on the effects of benztropine, cocaine and nomifensine on electrically evoked dopamine overflow and rate of re-uptake in the caudate putamen and nucleus accumbens in the rat brain slice. |
1995-02-14 |
2023-08-12 |
rat |
| W D Essman, A Singh, I Luck. Serotonergic properties of cocaine: effects on a 5-HT2 receptor-mediated behavior and on extracellular concentrations of serotonin and dopamine. Pharmacology, biochemistry, and behavior. vol 49. issue 1. 1995-02-07. PMID:7816859. |
the effects of cocaine on extracellular concentrations of da and 5-ht in the nucleus accumbens were examined using in vivo microdialysis in a separate group of anesthetized rats. |
1995-02-07 |
2023-08-12 |
rat |
| G Torres, C Rivier, F Weis. A ketamine mixture anesthetic inhibits neuroendocrine and behavioral consequences of cocaine administration. Brain research. vol 656. issue 1. 1995-01-31. PMID:7804843. |
administration of the anesthetic mixture did not appear to impair the dopamine (da) re-uptake blocking properties of cocaine in the nucleus accumbens since substantial increases in extracellular da were observed in the presence of the ketamine mixture. |
1995-01-31 |
2023-08-12 |
rat |
| M Xu, X T Hu, D C Cooper, R Moratalla, A M Graybiel, F J White, S Tonegaw. Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice. Cell. vol 79. issue 6. 1995-01-26. PMID:8001143. |
electrophysiological studies of dopamine-sensitive nucleus accumbens neurons demonstrated a marked reduction in the inhibitory effects of cocaine on the generation of action potentials. |
1995-01-26 |
2023-08-12 |
mouse |
| M Xu, X T Hu, D C Cooper, R Moratalla, A M Graybiel, F J White, S Tonegaw. Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice. Cell. vol 79. issue 6. 1995-01-26. PMID:8001143. |
these results demonstrate the essential role of the d1 receptor in the locomotor stimulant effects of cocaine and in dopamine-mediated neurophysiological effects within the nucleus accumbens. |
1995-01-26 |
2023-08-12 |
mouse |
| R M Carelli, S A Deadwyle. A comparison of nucleus accumbens neuronal firing patterns during cocaine self-administration and water reinforcement in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 12. 1995-01-17. PMID:7996208. |
a comparison of nucleus accumbens neuronal firing patterns during cocaine self-administration and water reinforcement in rats. |
1995-01-17 |
2023-08-12 |
human |
| R M Carelli, S A Deadwyle. A comparison of nucleus accumbens neuronal firing patterns during cocaine self-administration and water reinforcement in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 12. 1995-01-17. PMID:7996208. |
the firing patterns of nucleus accumbens (na) neurons in the rat were recorded during cocaine self-administration and responding for water. |
1995-01-17 |
2023-08-12 |
human |
| M H Baumann, G U Char, B R De Costa, K C Rice, R B Rothma. GBR12909 attenuates cocaine-induced activation of mesolimbic dopamine neurons in the rat. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996429. |
cocaine, gbr12909 and combinations of the two drugs on da overflow in the nucleus accumbens of awake rats. |
1995-01-17 |
2023-08-12 |
human |