| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Wilson, S J Kis. The vesicular monoamine transporter, in contrast to the dopamine transporter, is not altered by chronic cocaine self-administration in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627383. |
however, in sequential sections from the same animals, [3h]dtbz binding was normal throughout the entire rostrocaudal extent of the basal ganglia (including striatum and nucleus accumbens), cerebral cortex, and diencephalon, as well as in midbrain and brainstem monoamine cell body regions, both on the last day of cocaine access and after 3 weeks of drug withdrawal. |
1996-06-21 |
2023-08-12 |
rat |
| N H Chen, C Xu, L L Coffey, M E Reit. [3H]WIN 35,428 [2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] binding to rat brain membranes. Comparing dopamine cell body areas with nerve terminal regions. Biochemical pharmacology. vol 51. issue 4. 1996-06-13. PMID:8619903. |
the results suggest that somatodendritic and axonal dopamine transporters in the ventral mesencephalon and nucleus accumbens are not very different as far as their binding domains for uptake blockers such as cocaine and gbr 12909 are concerned. |
1996-06-13 |
2023-08-12 |
rat |
| F E Pontieri, G Tanda, G Di Chiar. Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 26. 1996-06-07. PMID:8618890. |
intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. |
1996-06-07 |
2023-08-12 |
rat |
| R M Carelli, S A Deadwyle. Dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613945. |
dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. |
1996-06-06 |
2023-08-12 |
rat |
| R M Carelli, S A Deadwyle. Dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613945. |
at the initiation of cocaine self-administration sessions, neurons in the rat nucleus accumbens (na) exhibit a spontaneous transition in firing rate from activity unrelated to the reinforced response to one of four types of patterned discharges. |
1996-06-06 |
2023-08-12 |
rat |
| F G Kaddis, N J Uretsky, L J Wallac. DNQX in the nucleus accumbens inhibits cocaine-induced conditioned place preference. Brain research. vol 697. issue 1-2. 1996-04-11. PMID:8593597. |
the goal of these experiments was to determine whether ampa receptor antagonist injected into the nucleus accumbens could block conditioned place preference elicited by cocaine under conditions where dopaminergic antagonists do not inhibit acquisition of place preference. |
1996-04-11 |
2023-08-12 |
rat |
| F G Kaddis, N J Uretsky, L J Wallac. DNQX in the nucleus accumbens inhibits cocaine-induced conditioned place preference. Brain research. vol 697. issue 1-2. 1996-04-11. PMID:8593597. |
dnqx (1 microgram/0.5 microliter), injected into the nucleus accumbens just before systemic injections of cocaine (20 mg/kg i.p.) |
1996-04-11 |
2023-08-12 |
rat |
| J Chen, R Marmur, W Paredes, A Pulles, E L Gardne. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. Life sciences. vol 58. issue 8. 1996-04-10. PMID:8594313. |
systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. |
1996-04-10 |
2023-08-12 |
rat |
| J Chen, R Marmur, W Paredes, A Pulles, E L Gardne. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. Life sciences. vol 58. issue 8. 1996-04-10. PMID:8594313. |
on the next day, rats were challenged with an acute dose of cocaine administered by one of two routes (systemic or intracranial), and extra-cellular dopamine (da) in the nucleus accumbens (acb) was measured by in vivo microdialysis. |
1996-04-10 |
2023-08-12 |
rat |
| J Chen, R Marmur, W Paredes, A Pulles, E L Gardne. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. Life sciences. vol 58. issue 8. 1996-04-10. PMID:8594313. |
rats acutely challenged systemically with 20 mg/kg cocaine showed enhanced acb extracellular da levels (compared to control rats that had not previously received chronic cocaine). |
1996-04-10 |
2023-08-12 |
rat |
| J Chen, R Marmur, W Paredes, A Pulles, E L Gardne. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. Life sciences. vol 58. issue 8. 1996-04-10. PMID:8594313. |
however, rats acutely challenged with intracranial cocaine by perfusion of 10(-5) m cocaine directly into the acb did not. |
1996-04-10 |
2023-08-12 |
rat |
| J Chen, R Marmur, W Paredes, A Pulles, E L Gardne. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. Life sciences. vol 58. issue 8. 1996-04-10. PMID:8594313. |
it is suggested that both the development and triggering of cocaine sensitization, as manifested by enhanced acb da content to subsequent acute cocaine challenge, may involve more than just neural mechanisms occurring locally within the acb. |
1996-04-10 |
2023-08-12 |
rat |
| A V Azaryan, L J Coughlin, B Búzás, B J Clock, B M Co. Effect of chronic cocaine treatment on mu- and delta-opioid receptor mRNA levels in dopaminergically innervated brain regions. Journal of neurochemistry. vol 66. issue 2. 1996-04-03. PMID:8592112. |
a significant increase in the level of mor mrna was detected in nucleus accumbens after 3 days of cocaine treatment. |
1996-04-03 |
2023-08-12 |
rat |
| M Y Li, Q S Yan, L L Coffey, M E Reit. Extracellular dopamine, norepinephrine, and serotonin in the nucleus accumbens of freely moving rats during intracerebral dialysis with cocaine and other monoamine uptake blockers. Journal of neurochemistry. vol 66. issue 2. 1996-04-03. PMID:8592125. |
extracellular dopamine, norepinephrine, and serotonin in the nucleus accumbens of freely moving rats during intracerebral dialysis with cocaine and other monoamine uptake blockers. |
1996-04-03 |
2023-08-12 |
rat |
| M Y Li, Q S Yan, L L Coffey, M E Reit. Extracellular dopamine, norepinephrine, and serotonin in the nucleus accumbens of freely moving rats during intracerebral dialysis with cocaine and other monoamine uptake blockers. Journal of neurochemistry. vol 66. issue 2. 1996-04-03. PMID:8592125. |
the present results suggest a contribution of the increase in norepinephrine, but not serotonin, to the enhancement of dopamine after cocaine applied focally in the nucleus accumbens. |
1996-04-03 |
2023-08-12 |
rat |
| S B Caine, S C Heinrichs, V L Coffin, G F Koo. Effects of the dopamine D-1 antagonist SCH 23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat. Brain research. vol 692. issue 1-2. 1996-02-20. PMID:8548319. |
these results support a role for d-1 dopamine receptors in the nucleus accumbens and amygdala in the effects of self-administered cocaine, and suggest that d-1 receptors in certain portions of the 'extended amygdala' may be an important substrate for the reinforcing actions of cocaine. |
1996-02-20 |
2023-08-12 |
rat |
| H E Nye, B T Hope, M B Kelz, M Iadarola, E J Nestle. Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 275. issue 3. 1996-02-01. PMID:8531143. |
pharmacological studies of the regulation of chronic fos-related antigen induction by cocaine in the striatum and nucleus accumbens. |
1996-02-01 |
2023-08-12 |
rat |
| H E Nye, B T Hope, M B Kelz, M Iadarola, E J Nestle. Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 275. issue 3. 1996-02-01. PMID:8531143. |
previous work has demonstrated that chronic administration of cocaine induces apparently novel fos-like transcription factors, termed chronic fras (fos-related antigens), in the rat striatum and nucleus accumbens. |
1996-02-01 |
2023-08-12 |
rat |
| H E Nye, B T Hope, M B Kelz, M Iadarola, E J Nestle. Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 275. issue 3. 1996-02-01. PMID:8531143. |
pretreatment with a d1 receptor antagonist, which did not affect chronic fra levels by itself, attenuated cocaine induction of the chronic fras in striatum and nucleus accumbens. |
1996-02-01 |
2023-08-12 |
rat |
| R A Wise, P Newton, K Leeb, B Burnette, D Pocock, J B Justic. Fluctuations in nucleus accumbens dopamine concentration during intravenous cocaine self-administration in rats. Psychopharmacology. vol 120. issue 1. 1995-12-07. PMID:7480530. |
fluctuations in nucleus accumbens dopamine concentration during intravenous cocaine self-administration in rats. |
1995-12-07 |
2023-08-12 |
rat |