| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L H Parsons, S B Caine, P Sokoloff, J C Schwartz, G F Koob, F Weis. Neurochemical evidence that postsynaptic nucleus accumbens D3 receptor stimulation enhances cocaine reinforcement. Journal of neurochemistry. vol 67. issue 3. 1996-10-02. PMID:8752115. |
these findings indicate that postsynaptic d3 receptor stimulation in the nucleus accumbens enhances the reinforcing properties of cocaine. |
1996-10-02 |
2023-08-12 |
rat |
| D Boulay, D Duterte-Boucher, I Leroux-Nicollet, L Naudon, J Costenti. Locomotor sensitization and decrease in [3H]mazindol binding to the dopamine transporter in the nucleus accumbens are delayed after chronic treatments by GBR12783 or cocaine. The Journal of pharmacology and experimental therapeutics. vol 278. issue 1. 1996-09-23. PMID:8764367. |
locomotor sensitization and decrease in [3h]mazindol binding to the dopamine transporter in the nucleus accumbens are delayed after chronic treatments by gbr12783 or cocaine. |
1996-09-23 |
2023-08-12 |
rat |
| M S Reid, K Hsu, B K Tolliver, C A Crawford, S P Berge. Evidence for the involvement of phospholipase A2 mechanisms in the development of stimulant sensitization. The Journal of pharmacology and experimental therapeutics. vol 276. issue 3. 1996-09-20. PMID:8786557. |
local injections of melittin (0.1 microgram/0.4 microliter) into the ventral tegmental area sensitized the subsequent stimulation of locomotor activity, stereotypy and nucleus accumbens dopamine release by cocaine, when tested 72 hr later. |
1996-09-20 |
2023-08-12 |
rat |
| G F Koob, B Caine, A Markou, L Pulvirenti, F Weis. Role for the mesocortical dopamine system in the motivating effects of cocaine. NIDA research monograph. vol 145. 1996-09-18. PMID:8742805. |
this mesocorticolimbic da system innervates the region of the nucleus accumbens (nacc) (ventral striatum) in the anterior part of the basal forebrain and appears to play a critical role in mediating the acute reinforcing effects of cocaine and amphetamine. |
1996-09-18 |
2023-08-12 |
rat |
| C A Heidbreder, A C Thompson, T S Shippenber. Role of extracellular dopamine in the initiation and long-term expression of behavioral sensitization to cocaine. The Journal of pharmacology and experimental therapeutics. vol 278. issue 2. 1996-09-18. PMID:8768696. |
the present study sought to characterize basal dialysate dopamine (da) concentrations within the nucleus accumbens (nac), 2, 12 or 22 days after the cessation of either repeated cocaine (20 mg/kg/day x 5 days) or saline (1.0 ml/kg/day x 5 days) treatment. |
1996-09-18 |
2023-08-12 |
Not clear |
| J D Wagstaff, J W Gibb, G R Hanso. Microdialysis assessment of methamphetamine-induced changes in extracellular neurotensin in the striatum and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 278. issue 2. 1996-09-18. PMID:8768703. |
stimulants of abuse such as cocaine and methamphetamine (meth) have dramatic effects on tissue neurotensin (nt) levels in the striatum and nucleus accumbens. |
1996-09-18 |
2023-08-12 |
rat |
| R C Pierce, K Bell, P Duffy, P W Kaliva. Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 4. 1996-09-18. PMID:8778304. |
repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. |
1996-09-18 |
2023-08-12 |
rat |
| R C Pierce, K Bell, P Duffy, P W Kaliva. Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 4. 1996-09-18. PMID:8778304. |
at 2-3 weeks after the last daily injection, four experiments were performed to assess changes in excitatory amino acid (eaa) transmission in the nucleus accumbens produced by repeated cocaine administration. |
1996-09-18 |
2023-08-12 |
rat |
| R C Pierce, K Bell, P Duffy, P W Kaliva. Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 4. 1996-09-18. PMID:8778304. |
these results indicate that repeated cocaine administration increases eaa transmission in the nucleus accumbens only in rats that develop behavioral sensitization to cocaine. |
1996-09-18 |
2023-08-12 |
rat |
| B A Morrow, J R Taylor, R H Rot. Prior exposure to cocaine diminishes behavioral and biochemical responses to aversive conditioning: reversal by glycine/N-methyl-D-aspartate antagonist co-treatment. Neuroscience. vol 69. issue 1. 1996-07-08. PMID:8637621. |
additionally, the elevated metabolic activity of dopamine in the medial prefrontal cortex, nucleus accumbens and ventral tegmental area associated with aversive conditioning was diminished in rats pre-exposed to cocaine. |
1996-07-08 |
2023-08-12 |
rat |
| L L Peoples, M O Wes. Phasic firing of single neurons in the rat nucleus accumbens correlated with the timing of intravenous cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627379. |
phasic firing of single neurons in the rat nucleus accumbens correlated with the timing of intravenous cocaine self-administration. |
1996-06-21 |
2023-08-12 |
rat |
| L L Peoples, M O Wes. Phasic firing of single neurons in the rat nucleus accumbens correlated with the timing of intravenous cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627379. |
to examine potential neural mechanisms involved in cocaine self-administration, the activity of single neurons in the nucleus accumbens of rats was recorded during intravenous cocaine self-administration. |
1996-06-21 |
2023-08-12 |
rat |
| J M Wilson, S J Kis. The vesicular monoamine transporter, in contrast to the dopamine transporter, is not altered by chronic cocaine self-administration in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627383. |
however, in sequential sections from the same animals, [3h]dtbz binding was normal throughout the entire rostrocaudal extent of the basal ganglia (including striatum and nucleus accumbens), cerebral cortex, and diencephalon, as well as in midbrain and brainstem monoamine cell body regions, both on the last day of cocaine access and after 3 weeks of drug withdrawal. |
1996-06-21 |
2023-08-12 |
rat |
| N H Chen, C Xu, L L Coffey, M E Reit. [3H]WIN 35,428 [2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] binding to rat brain membranes. Comparing dopamine cell body areas with nerve terminal regions. Biochemical pharmacology. vol 51. issue 4. 1996-06-13. PMID:8619903. |
the results suggest that somatodendritic and axonal dopamine transporters in the ventral mesencephalon and nucleus accumbens are not very different as far as their binding domains for uptake blockers such as cocaine and gbr 12909 are concerned. |
1996-06-13 |
2023-08-12 |
rat |
| F E Pontieri, G Tanda, G Di Chiar. Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 26. 1996-06-07. PMID:8618890. |
intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. |
1996-06-07 |
2023-08-12 |
rat |
| R M Carelli, S A Deadwyle. Dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613945. |
dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. |
1996-06-06 |
2023-08-12 |
rat |
| R M Carelli, S A Deadwyle. Dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613945. |
at the initiation of cocaine self-administration sessions, neurons in the rat nucleus accumbens (na) exhibit a spontaneous transition in firing rate from activity unrelated to the reinforced response to one of four types of patterned discharges. |
1996-06-06 |
2023-08-12 |
rat |
| F G Kaddis, N J Uretsky, L J Wallac. DNQX in the nucleus accumbens inhibits cocaine-induced conditioned place preference. Brain research. vol 697. issue 1-2. 1996-04-11. PMID:8593597. |
the goal of these experiments was to determine whether ampa receptor antagonist injected into the nucleus accumbens could block conditioned place preference elicited by cocaine under conditions where dopaminergic antagonists do not inhibit acquisition of place preference. |
1996-04-11 |
2023-08-12 |
rat |
| F G Kaddis, N J Uretsky, L J Wallac. DNQX in the nucleus accumbens inhibits cocaine-induced conditioned place preference. Brain research. vol 697. issue 1-2. 1996-04-11. PMID:8593597. |
dnqx (1 microgram/0.5 microliter), injected into the nucleus accumbens just before systemic injections of cocaine (20 mg/kg i.p.) |
1996-04-11 |
2023-08-12 |
rat |
| J Chen, R Marmur, W Paredes, A Pulles, E L Gardne. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. Life sciences. vol 58. issue 8. 1996-04-10. PMID:8594313. |
systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. |
1996-04-10 |
2023-08-12 |
rat |