| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S R Jones, P A Garris, R M Wightma. Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616424. |
the effects of cocaine and nomifensine on the uptake of dopamine have been compared in the caudate-putamen and nucleus accumbens of rat brain slices. |
1995-08-18 |
2023-08-12 |
rat |
| M J Miserendino, E J Nestle. Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens. Brain research. vol 674. issue 2. 1995-08-03. PMID:7796110. |
behavioral sensitization to cocaine: modulation by the cyclic amp system in the nucleus accumbens. |
1995-08-03 |
2023-08-12 |
rat |
| M J Miserendino, E J Nestle. Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens. Brain research. vol 674. issue 2. 1995-08-03. PMID:7796110. |
we have previously observed that chronic cocaine administration increases levels of adenylyl cyclase and camp-dependent protein kinase (pka) in the nucleus accumbens (nac). |
1995-08-03 |
2023-08-12 |
rat |
| C A Schad, J B Justice, S G Holtzma. Naloxone reduces the neurochemical and behavioral effects of amphetamine but not those of cocaine. European journal of pharmacology. vol 275. issue 1. 1995-07-10. PMID:7774666. |
amphetamine and cocaine dose-dependently increased extracellular dopamine in both the nucleus accumbens and striatum. |
1995-07-10 |
2023-08-12 |
rat |
| F R Sharp, J Liu, J Nickolenko, B Bontemp. NMDA and D1 receptors mediate induction of c-fos and junB genes in striatum following morphine administration: implications for studies of memory. Behavioural brain research. vol 66. issue 1-2. 1995-06-29. PMID:7755894. |
since the pattern of the morphine induction of c-fos and junb in striatum and nucleus accumbens was similar to that observed with cocaine and amphetamine [2,18,45,51], these data support current concepts that limbic striatum and nucleus accumbens are among the brain regions that mediate drug abuse [9,10,23,27,49]. |
1995-06-29 |
2023-08-12 |
Not clear |
| S R Jones, P A Garris, C D Kilts, R M Wightma. Comparison of dopamine uptake in the basolateral amygdaloid nucleus, caudate-putamen, and nucleus accumbens of the rat. Journal of neurochemistry. vol 64. issue 6. 1995-06-28. PMID:7760038. |
addition of a dopamine uptake inhibitor, cocaine or nomifensine (10 microm), to the perfusion buffer increased the apparent km value > 25-fold in slices of both the caudate-putamen and nucleus accumbens. |
1995-06-28 |
2023-08-12 |
rat |
| G R Hanson, N Singh, K Merchant, M Johnson, J W Gib. The role of NMDA receptor systems in neuropeptide responses to stimulants of abuse. Drug and alcohol dependence. vol 37. issue 2. 1995-06-26. PMID:7758400. |
high doses of stimulants of abuse, such as methamphetamine and cocaine, cause significant increases in the content of neurotension- and dynorphin-like immunoreactivity in the striatum and nucleus accumbens (approximately 200-600% of control) in the rat. |
1995-06-26 |
2023-08-12 |
rat |
| S E Hemby, C Co, D Reboussin, H M Davies, S I Dworkin, J E Smit. Comparison of a novel tropane analog of cocaine, 2 beta-propanoyl-3 beta-(4-tolyl) tropane with cocaine HCl in rats: nucleus accumbens extracellular dopamine concentration and motor activity. The Journal of pharmacology and experimental therapeutics. vol 273. issue 2. 1995-06-19. PMID:7752068. |
comparison of a novel tropane analog of cocaine, 2 beta-propanoyl-3 beta-(4-tolyl) tropane with cocaine hcl in rats: nucleus accumbens extracellular dopamine concentration and motor activity. |
1995-06-19 |
2023-08-12 |
rat |
| E A Kiyatkin, E A Stei. Fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study. Neuroscience. vol 64. issue 3. 1995-05-18. PMID:7715774. |
fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study. |
1995-05-18 |
2023-08-12 |
rat |
| E A Kiyatkin, E A Stei. Fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study. Neuroscience. vol 64. issue 3. 1995-05-18. PMID:7715774. |
high-speed chronoamperometry with nafion-coated monoamine-sensitive carbon fiber electrodes was used to estimate changes in extracellular dopamine concentration in the nucleus accumbens during cocaine self-administration behavior in rats. |
1995-05-18 |
2023-08-12 |
rat |
| F J White, X T Hu, X F Zhang, M E Wol. Repeated administration of cocaine or amphetamine alters neuronal responses to glutamate in the mesoaccumbens dopamine system. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714800. |
after five daily injections of either cocaine (15.0 mg/kg) or d-amphetamine (5.0 mg/kg), rats were subjected to in vivo single cell recording to determine the efficacy of iontophoretically administered glutamate in altering the firing of ventral tegmental area da neurons and nucleus accumbens neurons. |
1995-05-17 |
2023-08-12 |
rat |
| J M Wilson, J N Nobrega, W A Corrigall, K M Coen, K Shannak, S J Kis. Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine. Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704616. |
dopamine and metabolite levels were normal in all other brain areas examined, including striatum, nucleus accumbens and medial prefrontal cortex, at both 1 h and 4 weeks withdrawal from cocaine. |
1995-05-10 |
2023-08-12 |
rat |
| F Karoum, S J Chrapusta, R Brinjak, A Hitri, R J Wyat. Regional effects of amphetamine, cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain. British journal of pharmacology. vol 113. issue 4. 1995-04-19. PMID:7889297. |
the effects of single-dose regimens of amphetamine, cocaine, nomifensine and gbr 12909 on the dynamics of dopamine (da) release and metabolism were evaluated in the frontal cortex, hypothalamus, nucleus accumbens and striatum. |
1995-04-19 |
2023-08-12 |
rat |
| F Karoum, S J Chrapusta, R Brinjak, A Hitri, R J Wyat. Regional effects of amphetamine, cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain. British journal of pharmacology. vol 113. issue 4. 1995-04-19. PMID:7889297. |
a similar effect was produced by cocaine except in the nucleus accumbens. |
1995-04-19 |
2023-08-12 |
rat |
| F Karoum, S J Chrapusta, R Brinjak, A Hitri, R J Wyat. Regional effects of amphetamine, cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain. British journal of pharmacology. vol 113. issue 4. 1995-04-19. PMID:7889297. |
total da turnover was increased by gbr 12909 in the hypothalamus, nucleus accumbens and striatum, while cocaine and nomifensine increased it only in the nucleus accumbens and striatum respectively.8. |
1995-04-19 |
2023-08-12 |
rat |
| M E Wolf, C J Xue, F J White, S L Dahli. MK-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens. Brain research. vol 666. issue 2. 1995-04-13. PMID:7882032. |
mk-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens. |
1995-04-13 |
2023-08-12 |
rat |
| M E Wolf, C J Xue, F J White, S L Dahli. MK-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens. Brain research. vol 666. issue 2. 1995-04-13. PMID:7882032. |
to examine this issue, behavioral and microdialysis studies assessed the effect of pretreatment with 0.1 mg/kg mk-801 on the ability of amphetamine and cocaine to stimulate locomotor activity and elevate extracellular dopamine (da) levels in nucleus accumbens; this dose of mk-801 prevents sensitization when coadministered repeatedly with these stimulants. |
1995-04-13 |
2023-08-12 |
rat |
| M E Wolf, C J Xue, F J White, S L Dahli. MK-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens. Brain research. vol 666. issue 2. 1995-04-13. PMID:7882032. |
there was no effect of mk-801 pretreatment on the ability of amphetamine or cocaine to elevate extracellular da levels in nucleus accumbens. |
1995-04-13 |
2023-08-12 |
rat |
| J M Wilson, M E Carroll, S T Lac, L M DiStefano, S J Kis. Choline acetyltransferase activity is reduced in rat nucleus accumbens after unlimited access to self-administration of cocaine. Neuroscience letters. vol 180. issue 1. 1995-04-03. PMID:7877755. |
choline acetyltransferase activity is reduced in rat nucleus accumbens after unlimited access to self-administration of cocaine. |
1995-04-03 |
2023-08-12 |
rat |
| J M Wilson, M E Carroll, S T Lac, L M DiStefano, S J Kis. Choline acetyltransferase activity is reduced in rat nucleus accumbens after unlimited access to self-administration of cocaine. Neuroscience letters. vol 180. issue 1. 1995-04-03. PMID:7877755. |
these data suggest that chronic cocaine exposure might inhibit nucleus accumbens cholinergic neurones which could underlie some of the behavioral effects of cocaine. |
1995-04-03 |
2023-08-12 |
rat |