| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Wise, P Newton, K Leeb, B Burnette, D Pocock, J B Justic. Fluctuations in nucleus accumbens dopamine concentration during intravenous cocaine self-administration in rats. Psychopharmacology. vol 120. issue 1. 1995-12-07. PMID:7480530. |
fluctuations in extracellular dopamine and dopac levels in nucleus accumbens septi (nas) were monitored in 1-min microdialysis samples taken from rats engaged in intravenous cocaine self-administration. |
1995-12-07 |
2023-08-12 |
rat |
| J A Smith, Q Mo, H Guo, P M Kunko, S E Robinso. Cocaine increases extraneuronal levels of aspartate and glutamate in the nucleus accumbens. Brain research. vol 683. issue 2. 1995-11-21. PMID:7552364. |
cocaine increases extraneuronal levels of aspartate and glutamate in the nucleus accumbens. |
1995-11-21 |
2023-08-12 |
rat |
| S R White, G C Harris, K M Imel, M J Wheato. Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are enhanced following cocaine self-administration. Brain research. vol 681. issue 1-2. 1995-11-06. PMID:7552276. |
inhibitory effects of dopamine and methylenedioxymethamphetamine (mdma) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are enhanced following cocaine self-administration. |
1995-11-06 |
2023-08-12 |
rat |
| S R White, G C Harris, K M Imel, M J Wheato. Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are enhanced following cocaine self-administration. Brain research. vol 681. issue 1-2. 1995-11-06. PMID:7552276. |
one to 11 days after the last cocaine exposure, rats were anesthetized with urethane and effects of microiontophoretically-applied dopamine on glutamate-evoked firing of neurons in the nucleus accumbens and in the caudate/putamen were tested. |
1995-11-06 |
2023-08-12 |
rat |
| S R White, G C Harris, K M Imel, M J Wheato. Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are enhanced following cocaine self-administration. Brain research. vol 681. issue 1-2. 1995-11-06. PMID:7552276. |
dopamine produced a dose-dependent inhibition of glutamate-evoked firing in both the nucleus accumbens and the caudate/putamen of rats that had been repeatedly exposed to self-administered cocaine and in control rats. |
1995-11-06 |
2023-08-12 |
rat |
| S R White, G C Harris, K M Imel, M J Wheato. Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are enhanced following cocaine self-administration. Brain research. vol 681. issue 1-2. 1995-11-06. PMID:7552276. |
following cessation of repeated cocaine self-administration sessions, nucleus accumbens cells were also sensitized to the inhibitory effects of methylenedioxymethamphetamine (mdma), a drug that increases extracellular levels of da and serotonin in the nucleus accumbens. |
1995-11-06 |
2023-08-12 |
rat |
| S R White, G C Harris, K M Imel, M J Wheato. Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are enhanced following cocaine self-administration. Brain research. vol 681. issue 1-2. 1995-11-06. PMID:7552276. |
this sensitization to da- and mdma-induced inhibition in the nucleus accumbens and in the striatum indicates that long-term neuroadaptations occur in these regions of the nervous system following repeated exposure to self-administered cocaine. |
1995-11-06 |
2023-08-12 |
rat |
| L H Parsons, G F Koob, F Weis. Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine. The Journal of pharmacology and experimental therapeutics. vol 274. issue 3. 1995-10-25. PMID:7562486. |
serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine. |
1995-10-25 |
2023-08-12 |
rat |
| L H Parsons, G F Koob, F Weis. Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine. The Journal of pharmacology and experimental therapeutics. vol 274. issue 3. 1995-10-25. PMID:7562486. |
to test the hypothesis that cocaine withdrawal is associated with abnormalities in serotonin (5-ht) neurotransmission, 5-ht concentrations in the nucleus accumbens (nac) of rats were analyzed with microdialysis both during and after 12 h of unlimited-access intravenous cocaine self-administration. |
1995-10-25 |
2023-08-12 |
rat |
| D J Henry, F J Whit. The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 9. 1995-10-12. PMID:7666211. |
the persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons. |
1995-10-12 |
2023-08-12 |
Not clear |
| D J Henry, F J Whit. The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 9. 1995-10-12. PMID:7666211. |
the present experiments used behavioral and single-cell electrophysiological techniques to determine the persistence of sensitization and of enhanced postsynaptic responses to cocaine within the nucleus accumbens following various periods of withdrawal from repeated cocaine treatment (10 mg/kg i.p., twice daily, 14 d). |
1995-10-12 |
2023-08-12 |
Not clear |
| D J Henry, F J Whit. The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 9. 1995-10-12. PMID:7666211. |
a similar time course was observed for the enhanced efficacy of cocaine-induced inhibition of nucleus accumbens neurons, whether cocaine was administered systemically or locally by microiontophoresis. |
1995-10-12 |
2023-08-12 |
Not clear |
| S L Chang, V Kenigs, R L Moldow, J E Zadin. Chronic treatment with morphine and ethanol, but not cocaine, attenuates IL-1 beta activation of FOS expression in the rat hypothalamic paraventricular nucleus. Advances in experimental medicine and biology. vol 373. 1995-10-12. PMID:7668153. |
cocaine, which induced fos-ir in the caudate-putamen (cpu), nucleus accumbens (nacc) and locus coeruleus (lc), however, did not induce fos-ir in the pvn. |
1995-10-12 |
2023-08-12 |
rat |
| J H Graham, J R Maher, S E Robinso. The effect of cocaine and other local anesthetics on central dopaminergic neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 274. issue 2. 1995-09-08. PMID:7636732. |
these studies provide strong evidence that the three esteratic local anesthetics cocaine, dimethocaine and procaine all increase the synaptic presence of da, as reflected in increased levels of 3-mt and the ratio of 3-mt to da, in the striatum, nucleus accumbens and prefrontal cortex. |
1995-09-08 |
2023-08-12 |
rat |
| R C Pierce, P Duffy, P W Kaliva. Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens. Synapse (New York, N.Y.). vol 20. issue 1. 1995-08-31. PMID:7624827. |
sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens. |
1995-08-31 |
2023-08-12 |
rat |
| R C Pierce, P Duffy, P W Kaliva. Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens. Synapse (New York, N.Y.). vol 20. issue 1. 1995-08-31. PMID:7624827. |
in order to evaluate this hypothesis, we administered cocaine to rats daily (15 mg/kg ip x 2 days, 30 mg/kg ip x 5 days) and then monitored nucleus accumbens dopamine during the local administration (through the dialysis probe) of the d2/d3 agonist, quinpirole (0, 0.1, 1, and 10 microm). |
1995-08-31 |
2023-08-12 |
rat |
| J E Williams, W Wieczorek, P Willner, Z L Kru. Parametric analysis of the effects of cocaine and cocaine pretreatment on dopamine release in the nucleus accumbens measured by fast cyclic voltammetry. Brain research. vol 678. issue 1-2. 1995-08-30. PMID:7620892. |
parametric analysis of the effects of cocaine and cocaine pretreatment on dopamine release in the nucleus accumbens measured by fast cyclic voltammetry. |
1995-08-30 |
2023-08-12 |
rat |
| A Pap, C W Bradberr. Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616389. |
excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens. |
1995-08-18 |
2023-08-12 |
Not clear |
| A Pap, C W Bradberr. Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616389. |
our results suggest that both n-methyl-daspartate and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate subtypes of excitatory amino acid antagonist receptors may contribute to the stimulatory effect of cocaine on extracellular dopamine in the nucleus accumbens. |
1995-08-18 |
2023-08-12 |
Not clear |
| S R Jones, P A Garris, R M Wightma. Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616424. |
different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens. |
1995-08-18 |
2023-08-12 |
rat |