| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Turchan, B Przewłocka, G Toth, W Lasoń, A Borsodi, R Przewłock. The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat. Neuroscience. vol 91. issue 3. 1999-10-08. PMID:10391475. |
the present study was carried out to evaluate the effect of morphine, cocaine and ethanol on the density of opioid receptors in the nucleus accumbens and striatum of rat brain. |
1999-10-08 |
2023-08-12 |
rat |
| J Turchan, B Przewłocka, G Toth, W Lasoń, A Borsodi, R Przewłock. The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat. Neuroscience. vol 91. issue 3. 1999-10-08. PMID:10391475. |
repeated morphine administration decreased the receptor density after both ligands of the delta receptor in the nucleus accumbens after 3, 24 and 48 h, and in the striatum after 24 and 48 h. the density of [3h]ile5,6deltorphin b binding remained unchanged in both structures following repeated cocaine administration. |
1999-10-08 |
2023-08-12 |
rat |
| J Turchan, B Przewłocka, G Toth, W Lasoń, A Borsodi, R Przewłock. The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat. Neuroscience. vol 91. issue 3. 1999-10-08. PMID:10391475. |
after repeated cocaine administration either no changes (3 h) or a decrease in the binding of [3h]h-tyr-tic psi[ch2-nh]phe-phe-oh in the nucleus accumbens and striatum were observed after 24 and 48 h. ethanol did not influence the binding density of [3h]h-tyr-tic psi[ch2-nh]phe-phe-oh and [3h]ile5,6deltorphin b in the nucleus accumbens and striatum at any time-point studied. |
1999-10-08 |
2023-08-12 |
rat |
| P W Kalivas, P Duffy, S A Mackle. Interrupted expression of NAC-1 augments the behavioral responses to cocaine. Synapse (New York, N.Y.). vol 33. issue 2. 1999-09-27. PMID:10400893. |
nac-1 is an mrna that is increased selectively in the nucleus accumbens after acute and repeated cocaine administration. |
1999-09-27 |
2023-08-12 |
rat |
| P W Kalivas, P Duffy, S A Mackle. Interrupted expression of NAC-1 augments the behavioral responses to cocaine. Synapse (New York, N.Y.). vol 33. issue 2. 1999-09-27. PMID:10400893. |
antisense or control oligonucleotides were microinjected into the nucleus accumbens of rats to define the role of nac-1 in the behavioral responses to acute systemic cocaine. |
1999-09-27 |
2023-08-12 |
rat |
| P W Kalivas, P Duffy, S A Mackle. Interrupted expression of NAC-1 augments the behavioral responses to cocaine. Synapse (New York, N.Y.). vol 33. issue 2. 1999-09-27. PMID:10400893. |
the augmentation in cocaine motor behavior produced by nac-1 antisense pretreatment in the nucleus accumbens was not associated with increased dopamine release as estimated by microdialysis. |
1999-09-27 |
2023-08-12 |
rat |
| P W Kalivas, P Duffy, S A Mackle. Interrupted expression of NAC-1 augments the behavioral responses to cocaine. Synapse (New York, N.Y.). vol 33. issue 2. 1999-09-27. PMID:10400893. |
these data suggest that the induction of nac-1 by cocaine may be a compensatory mechanism that minimizes the behavioral impact of cocaine administration by regulating postsynaptic dopamine transmission within the nucleus accumbens. |
1999-09-27 |
2023-08-12 |
rat |
| G Hedou, J Feldon, C A Heidbrede. Effects of cocaine on dopamine in subregions of the rat prefrontal cortex and their efferents to subterritories of the nucleus accumbens. European journal of pharmacology. vol 372. issue 2. 1999-08-17. PMID:10395094. |
effects of cocaine on dopamine in subregions of the rat prefrontal cortex and their efferents to subterritories of the nucleus accumbens. |
1999-08-17 |
2023-08-12 |
rat |
| G Hedou, J Feldon, C A Heidbrede. Effects of cocaine on dopamine in subregions of the rat prefrontal cortex and their efferents to subterritories of the nucleus accumbens. European journal of pharmacology. vol 372. issue 2. 1999-08-17. PMID:10395094. |
the present study sought to investigate the contributions of the ventral prelimbic/infralimbic cortices and shell subterritory of the nucleus accumbens as well as the dorsal prelimbic/anterior cingulate cortices and core subregion of the nucleus accumbens to the acute systemic effects of cocaine (20 mg/kg i.p.) |
1999-08-17 |
2023-08-12 |
rat |
| G Hedou, J Feldon, C A Heidbrede. Effects of cocaine on dopamine in subregions of the rat prefrontal cortex and their efferents to subterritories of the nucleus accumbens. European journal of pharmacology. vol 372. issue 2. 1999-08-17. PMID:10395094. |
in contrast, cocaine significantly increased dialysate dopamine in the shell of the nucleus accumbens, whereas only a slight increase in dopamine was observed in the core subregion of the nucleus accumbens. |
1999-08-17 |
2023-08-12 |
rat |
| G Hedou, J Feldon, C A Heidbrede. Effects of cocaine on dopamine in subregions of the rat prefrontal cortex and their efferents to subterritories of the nucleus accumbens. European journal of pharmacology. vol 372. issue 2. 1999-08-17. PMID:10395094. |
in contrast, the magnitude of the locomotor response to cocaine became progressively larger as dopamine levels increased in the shell of the nucleus accumbens. |
1999-08-17 |
2023-08-12 |
rat |
| G Hedou, J Feldon, C A Heidbrede. Effects of cocaine on dopamine in subregions of the rat prefrontal cortex and their efferents to subterritories of the nucleus accumbens. European journal of pharmacology. vol 372. issue 2. 1999-08-17. PMID:10395094. |
these results show a dissociation in the pattern of dopamine release in subterritories of both the medial prefrontal cortex and nucleus accumbens in response to the acute systemic administration of cocaine. |
1999-08-17 |
2023-08-12 |
rat |
| Y L Hurd, P Svensson, M Ponté. The role of dopamine, dynorphin, and CART systems in the ventral striatum and amygdala in cocaine abuse. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415667. |
our experiments have been directed towards characterizing the specific alterations of dopamine and dynorphin systems during different stages following cocaine administration, as well as assessing the contribution of nucleus accumbens and amygdala dopamine levels to cocaine-intake behavior. |
1999-08-10 |
2023-08-12 |
rat |
| D C Mash, J K Stale. D3 dopamine and kappa opioid receptor alterations in human brain of cocaine-overdose victims. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415668. |
d3 receptor/cyclophilin mrna ratios in the nucleus accumbens were increased sixfold in cocaine-overdose victims over control values, suggesting that cocaine exposure also affects the expression of d3 receptor mrna. |
1999-08-10 |
2023-08-12 |
human |
| D C Mash, J K Stale. D3 dopamine and kappa opioid receptor alterations in human brain of cocaine-overdose victims. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415668. |
the number of kappa opioid receptors in the nucleus accumbens and other corticolimbic areas from cocaine fatalities was increased twofold as compared to control values. |
1999-08-10 |
2023-08-12 |
human |
| D L McKinzie, Z A Rodd-Henricks, C T Dagon, J M Murphy, W J McBrid. Cocaine is self-administered into the shell region of the nucleus accumbens in Wistar rats. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415705. |
cocaine is self-administered into the shell region of the nucleus accumbens in wistar rats. |
1999-08-10 |
2023-08-12 |
rat |
| G P Mark, A E Kinney, M C Grubb, A S Key. Involvement of acetylcholine in the nucleus accumbens in cocaine reinforcement. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415706. |
involvement of acetylcholine in the nucleus accumbens in cocaine reinforcement. |
1999-08-10 |
2023-08-12 |
Not clear |
| B M Prasad, T Hochstatter, B A Sor. Expression of cocaine sensitization: regulation by the medial prefrontal cortex. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363816. |
extracellular levels of dopamine are increased in response to systemic administration of cocaine in several brain areas including the nucleus accumbens and medial prefrontal cortex. |
1999-08-02 |
2023-08-12 |
rat |
| B M Prasad, T Hochstatter, B A Sor. Expression of cocaine sensitization: regulation by the medial prefrontal cortex. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363816. |
while the cocaine-induced increase in extracellular dopamine levels in the nucleus accumbens is augmented after repeated daily cocaine, the response of extracellular dopamine levels in the medial prefrontal cortex is attenuated. |
1999-08-02 |
2023-08-12 |
rat |
| B M Prasad, T Hochstatter, B A Sor. Expression of cocaine sensitization: regulation by the medial prefrontal cortex. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363816. |
since dopamine in the medial prefrontal cortex has an inhibitory effect on nucleus accumbens dopamine levels and locomotor activity, the role of medial prefrontal cortex dopamine tolerance in the expression of sensitized locomotor behavior was further examined by injection of d-amphetamine sulfate into the prelimbic portion of the medial prefrontal cortex just prior to cocaine challenge in cocaine-sensitized rats. |
1999-08-02 |
2023-08-12 |
rat |