| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y L Hurd, P Svensson, M Ponté. The role of dopamine, dynorphin, and CART systems in the ventral striatum and amygdala in cocaine abuse. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415667. |
our experiments have been directed towards characterizing the specific alterations of dopamine and dynorphin systems during different stages following cocaine administration, as well as assessing the contribution of nucleus accumbens and amygdala dopamine levels to cocaine-intake behavior. |
1999-08-10 |
2023-08-12 |
rat |
| D C Mash, J K Stale. D3 dopamine and kappa opioid receptor alterations in human brain of cocaine-overdose victims. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415668. |
d3 receptor/cyclophilin mrna ratios in the nucleus accumbens were increased sixfold in cocaine-overdose victims over control values, suggesting that cocaine exposure also affects the expression of d3 receptor mrna. |
1999-08-10 |
2023-08-12 |
human |
| D C Mash, J K Stale. D3 dopamine and kappa opioid receptor alterations in human brain of cocaine-overdose victims. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415668. |
the number of kappa opioid receptors in the nucleus accumbens and other corticolimbic areas from cocaine fatalities was increased twofold as compared to control values. |
1999-08-10 |
2023-08-12 |
human |
| D L McKinzie, Z A Rodd-Henricks, C T Dagon, J M Murphy, W J McBrid. Cocaine is self-administered into the shell region of the nucleus accumbens in Wistar rats. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415705. |
cocaine is self-administered into the shell region of the nucleus accumbens in wistar rats. |
1999-08-10 |
2023-08-12 |
rat |
| G P Mark, A E Kinney, M C Grubb, A S Key. Involvement of acetylcholine in the nucleus accumbens in cocaine reinforcement. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415706. |
involvement of acetylcholine in the nucleus accumbens in cocaine reinforcement. |
1999-08-10 |
2023-08-12 |
Not clear |
| B M Prasad, T Hochstatter, B A Sor. Expression of cocaine sensitization: regulation by the medial prefrontal cortex. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363816. |
extracellular levels of dopamine are increased in response to systemic administration of cocaine in several brain areas including the nucleus accumbens and medial prefrontal cortex. |
1999-08-02 |
2023-08-12 |
rat |
| B M Prasad, T Hochstatter, B A Sor. Expression of cocaine sensitization: regulation by the medial prefrontal cortex. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363816. |
while the cocaine-induced increase in extracellular dopamine levels in the nucleus accumbens is augmented after repeated daily cocaine, the response of extracellular dopamine levels in the medial prefrontal cortex is attenuated. |
1999-08-02 |
2023-08-12 |
rat |
| B M Prasad, T Hochstatter, B A Sor. Expression of cocaine sensitization: regulation by the medial prefrontal cortex. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363816. |
since dopamine in the medial prefrontal cortex has an inhibitory effect on nucleus accumbens dopamine levels and locomotor activity, the role of medial prefrontal cortex dopamine tolerance in the expression of sensitized locomotor behavior was further examined by injection of d-amphetamine sulfate into the prelimbic portion of the medial prefrontal cortex just prior to cocaine challenge in cocaine-sensitized rats. |
1999-08-02 |
2023-08-12 |
rat |
| Y Itzhak, J L Martin, M D Black, S F Al. Effect of the dopaminergic neurotoxin MPTP on cocaine-induced locomotor sensitization. Pharmacology, biochemistry, and behavior. vol 63. issue 1. 1999-07-28. PMID:10340529. |
the blockade of dopamine (da) uptake via the dopamine transporter (dat) in the nucleus accumbens (nac) and striatum by cocaine has a major role in the reinforcing and psychomotor stimulating effects of the drug. |
1999-07-28 |
2023-08-12 |
mouse |
| E M Vernotica, J S Rosenblatt, J I Morrel. Microinfusion of cocaine into the medial preoptic area or nucleus accumbens transiently impairs maternal behavior in the rat. Behavioral neuroscience. vol 113. issue 2. 1999-07-15. PMID:10357462. |
microinfusion of cocaine into the medial preoptic area or nucleus accumbens transiently impairs maternal behavior in the rat. |
1999-07-15 |
2023-08-12 |
rat |
| E M Vernotica, J S Rosenblatt, J I Morrel. Microinfusion of cocaine into the medial preoptic area or nucleus accumbens transiently impairs maternal behavior in the rat. Behavioral neuroscience. vol 113. issue 2. 1999-07-15. PMID:10357462. |
cocaine was microinfused bilaterally (50 microg/0.5 microl/side) into the medial preoptic area (mpoa) or nucleus accumbens (na), 2 regions within the rat brain neural circuit known to mediate maternal behavior (mb). |
1999-07-15 |
2023-08-12 |
rat |
| C R Ashby, R Rohatgi, J Ngosuwan, T Borda, M R Gerasimov, A E Morgan, S Kushner, J D Brodie, S L Dewe. Implication of the GABA(B) receptor in gamma vinyl-GABA's inhibition of cocaine-induced increases in nucleus accumbens dopamine. Synapse (New York, N.Y.). vol 31. issue 2. 1999-07-12. PMID:10024012. |
in an effort to better understand the mechanisms underlying this inhibition, we examined the effect of the selective gaba(b) receptor antagonist sch 50911 on the gvg-induced decrease in cocaine's elevation of extracellular da concentrations in the nucleus accumbens (nacc). |
1999-07-12 |
2023-08-12 |
Not clear |
| C A Heidbreder, T Oertle, J Feldo. Dopamine and serotonin imbalances in the left anterior cingulate and pyriform cortices following the repeated intermittent administration of cocaine. Neuroscience. vol 89. issue 3. 1999-07-07. PMID:10199606. |
studies on the neurobiology of cocaine abuse suggest that cocaine directly modifies the activity of dopamine neurons projecting from the dopamine-synthesizing cells of the ventral tegmental area to the nucleus accumbens. |
1999-07-07 |
2023-08-12 |
Not clear |
| G P Mark, A Hajnal, A E Kinney, A S Key. Self-administration of cocaine increases the release of acetylcholine to a greater extent than response-independent cocaine in the nucleus accumbens of rats. Psychopharmacology. vol 143. issue 1. 1999-07-02. PMID:10227079. |
self-administration of cocaine increases the release of acetylcholine to a greater extent than response-independent cocaine in the nucleus accumbens of rats. |
1999-07-02 |
2023-08-12 |
rat |
| L Churchill, C J Swanson, M Urbina, P W Kaliva. Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349849. |
repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. |
1999-06-14 |
2023-08-12 |
human |
| L Churchill, C J Swanson, M Urbina, P W Kaliva. Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349849. |
increased glutamate transmission in the nucleus accumbens and ventral tegmental area has been proposed as a mechanism underlying sensitized behavioral responses to repeated cocaine administration. |
1999-06-14 |
2023-08-12 |
human |
| G R King, Z Xiong, E H Ellinwoo. Withdrawal from continuous cocaine administration: time dependent changes in accumbens 5-HT3 receptor function and behavioral tolerance. Psychopharmacology. vol 142. issue 4. 1999-06-10. PMID:10229059. |
we have previously reported that continuous cocaine administration functionally down regulates 5-ht3 receptors in the nucleus accumbens. |
1999-06-10 |
2023-08-12 |
rat |
| B A Horger, C A Iyasere, M T Berhow, C J Messer, E J Nestler, J R Taylo. Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 10. 1999-06-01. PMID:10234039. |
in experiment 1, bdnf was infused into the nucleus accumbens (nac) or ventral tegmental area over 2 weeks via chronically implanted minipumps (1-2.5 microgram/d), and the psychomotor stimulant effects of cocaine (5-15 mg/kg, i.p.) |
1999-06-01 |
2023-08-12 |
mouse |
| T E Robinson, B Kol. Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. The European journal of neuroscience. vol 11. issue 5. 1999-05-26. PMID:10215912. |
alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. |
1999-05-26 |
2023-08-12 |
rat |
| R M Philpot, C L Kirstei. Repeated cocaine exposure: effects on catecholamines in the nucleus accumbens septi of periadolescent animals. Pharmacology, biochemistry, and behavior. vol 62. issue 3. 1999-05-17. PMID:10080238. |
repeated cocaine exposure: effects on catecholamines in the nucleus accumbens septi of periadolescent animals. |
1999-05-17 |
2023-08-12 |
Not clear |