All Relations between cocaine and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
J Y Chang, P H Janak, D J Woodwar. Neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. Neuroscience. vol 99. issue 3. 2000-11-07. PMID:11029536. in addition, the finding that correlated activity within the nucleus accumbens more often precedes that of the medial prefrontal cortex suggests that the nucleus accumbens may play a prime role in the initiation of cocaine self-administration. 2000-11-07 2023-08-12 rat
K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. three weeks following the last daily injection dialysis probes were placed into the nucleus accumbens and all rats were injected with saline followed by cocaine. 2000-10-11 2023-08-12 rat
K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. in this study it was found that the motor stimulant response elicited by cocaine was blunted by pretreatment of the nucleus accumbens with 6-cyano-7-nitroquinoxaline-2,3-dione only in animals receiving daily cocaine injections in the paired environment. 2000-10-11 2023-08-12 rat
K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. these data support a hypothesis that environmental stimuli previously associated with daily cocaine administration can modulate glutamate transmission in the nucleus accumbens in a manner affecting cocaine-induced behavior. 2000-10-11 2023-08-12 rat
K K Szumlinski, I M Maisonneuve, S D Glic. Differential effects of ibogaine on behavioural and dopamine sensitization to cocaine. European journal of pharmacology. vol 398. issue 2. 2000-10-05. PMID:10854838. however, while ibogaine pretreatment did not significantly alter the dopamine response in the nucleus accumbens to acute cocaine, it abolished the expression of cocaine-induced dopamine sensitization. 2000-10-05 2023-08-12 rat
E A Kiyatkin, D E Kiyatkin, G V Rebe. Phasic inhibition of dopamine uptake in nucleus accumbens induced by intravenous cocaine in freely behaving rats. Neuroscience. vol 98. issue 4. 2000-09-27. PMID:10891616. phasic inhibition of dopamine uptake in nucleus accumbens induced by intravenous cocaine in freely behaving rats. 2000-09-27 2023-08-12 rat
E A Kiyatkin, D E Kiyatkin, G V Rebe. Phasic inhibition of dopamine uptake in nucleus accumbens induced by intravenous cocaine in freely behaving rats. Neuroscience. vol 98. issue 4. 2000-09-27. PMID:10891616. a new approach combining fast-scan cyclic voltammetry with iontophoretic dopamine delivery was used in freely behaving rats to evaluate the time-course of dopamine uptake inhibition in nucleus accumbens induced by intravenous cocaine at a dose (1.0mg/kg) known to maintain self-administration behavior. 2000-09-27 2023-08-12 rat
A Rosin, I van der Ploeg, J Georgiev. Basal and cocaine-induced opioid receptor gene expression in the rat CNS analyzed by competitive reverse transcription PCR. Brain research. vol 872. issue 1-2. 2000-09-20. PMID:10924681. the data suggest a selective effect on kappa receptor expression in the nucleus accumbens as a consequence of 'binge' cocaine use. 2000-09-20 2023-08-12 rat
M S Todtenkopf, K R De Leon, J R Stella. Repeated cocaine treatment alters tyrosine hydroxylase in the rat nucleus accumbens. Brain research bulletin. vol 52. issue 5. 2000-09-14. PMID:10922520. repeated cocaine treatment alters tyrosine hydroxylase in the rat nucleus accumbens. 2000-09-14 2023-08-12 rat
M R Gerasimov, W K Schiffer, J D Brodie, I C Lennon, S J Taylor, S L Dewe. gamma-aminobutyric acid mimetic drugs differentially inhibit the dopaminergic response to cocaine. European journal of pharmacology. vol 395. issue 2. 2000-09-06. PMID:10794818. we previously demonstrated that increased gamma-aminobutyric acid (gaba)-ergic activity produced by gamma-vinyl gaba [d,l-4-amino-hex-5-enoic acid (vigabatrin(r))], an irreversible inhibitor of gaba-transaminase, attenuated cocaine, nicotine, heroin, alcohol, and methamphetamine-induced increases in extracellular nucleus accumbens dopamine as well as behaviors associated with these biochemical changes. 2000-09-06 2023-08-12 Not clear
S A Mackler, L Korutla, X Y Cha, M J Koebbe, K M Fournier, M S Bowers, P W Kaliva. NAC-1 is a brain POZ/BTB protein that can prevent cocaine-induced sensitization in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 16. 2000-08-31. PMID:10934270. adenoviral-mediated overexpression of nac-1 protein in the rat nucleus accumbens prevented the development but not the expression of behavioral sensitization produced by repeated administration of cocaine. 2000-08-31 2023-08-12 rat
T N Ferraro, G T Golden, W H Berrettini, E Gottheil, C H Yang, G R Cuppels, W H Voge. Cocaine intake by rats correlates with cocaine-induced dopamine changes in the nucleus accumbens shell. Pharmacology, biochemistry, and behavior. vol 66. issue 2. 2000-08-28. PMID:10880696. extracellular dopamine levels were determined by microdialysis in the core and shell of the nucleus accumbens and the frontal cortex of rats before and after an injection of cocaine (20 mg/kg, ip). 2000-08-28 2023-08-12 rat
T N Ferraro, G T Golden, W H Berrettini, E Gottheil, C H Yang, G R Cuppels, W H Voge. Cocaine intake by rats correlates with cocaine-induced dopamine changes in the nucleus accumbens shell. Pharmacology, biochemistry, and behavior. vol 66. issue 2. 2000-08-28. PMID:10880696. a significant negative correlation was found between cocaine-induced increases in extracellular dopamine in the shell of the nucleus accumbens and the voluntary intake of cocaine (r = -0.73, p < 0.01). 2000-08-28 2023-08-12 rat
R M Carelli, S G Ijame. Nucleus accumbens cell firing during maintenance, extinction, and reinstatement of cocaine self-administration behavior in rats. Brain research. vol 866. issue 1-2. 2000-08-07. PMID:10825479. nucleus accumbens cell firing during maintenance, extinction, and reinstatement of cocaine self-administration behavior in rats. 2000-08-07 2023-08-12 rat
R M Carelli, S G Ijame. Nucleus accumbens cell firing during maintenance, extinction, and reinstatement of cocaine self-administration behavior in rats. Brain research. vol 866. issue 1-2. 2000-08-07. PMID:10825479. electrophysiological recording procedures were used to examine nucleus accumbens (acb) cell firing in rats (n=13) during cocaine self-administration sessions consisting of three phases. 2000-08-07 2023-08-12 rat
S M Nicola, S A Deadwyle. Firing rate of nucleus accumbens neurons is dopamine-dependent and reflects the timing of cocaine-seeking behavior in rats on a progressive ratio schedule of reinforcement. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 14. 2000-08-03. PMID:10884336. we recorded neuronal spike activity from cells in the nucleus accumbens (nac) of rats responding on a pr schedule for cocaine reinforcement. 2000-08-03 2023-08-12 rat
Q Yan, M E Reith, S Ya. Enhanced accumbal dopamine release following 5-HT(2A) receptor stimulation in rats pretreated with intermittent cocaine. Brain research. vol 863. issue 1-2. 2000-07-14. PMID:10773215. this study was conducted to determine whether dopamine (da) release in the nucleus accumbens (nacc) following 5-ht(2a) receptor stimulation is potentiated by intermittent cocaine. 2000-07-14 2023-08-12 rat
R M Carelli, S G Ijames, A J Crumlin. Evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 11. 2000-06-15. PMID:10818162. evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward. 2000-06-15 2023-08-12 rat
R M Carelli, S G Ijames, A J Crumlin. Evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 11. 2000-06-15. PMID:10818162. electrophysiological recording procedures were used to examine nucleus accumbens (acb) cell firing in rats trained to press a lever on a multiple schedule [ fixed ratio (fr)1, fr1] for either two "natural" reinforcers (food and water), or a natural reinforcer and intravenous self-administration of cocaine. 2000-06-15 2023-08-12 rat
R M Carelli, S G Ijames, A J Crumlin. Evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 11. 2000-06-15. PMID:10818162. these findings indicate that in the well-trained animal, cocaine activates a neural circuit in the acb that is largely separate from the circuit that processes information about food and water reward. 2000-06-15 2023-08-12 rat