Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. |
2001-08-30 |
2023-08-12 |
Not clear |
Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
in vivo voltammetry was used to investigate the preferential increase of extracellular dopamine in the nucleus accumbens relative to the caudate-putamen after systemic cocaine administration. |
2001-08-30 |
2023-08-12 |
Not clear |
Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
all three drugs robustly increased electrically evoked levels of dopamine, and cocaine elevated dopamine signals to a greater extent in the nucleus accumbens. |
2001-08-30 |
2023-08-12 |
Not clear |
Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
under the present in vivo conditions, therefore, cocaine is a competitive inhibitor of dopamine uptake in both the nucleus accumbens and caudate-putamen. |
2001-08-30 |
2023-08-12 |
Not clear |
Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
the lower rates for dopamine release and uptake measured in the nucleus accumbens were found to underlie the preferential increase in extracellular dopamine after cocaine. |
2001-08-30 |
2023-08-12 |
Not clear |
S A Kushner, E M Unterwal. Chronic cocaine administration decreases the functional coupling of GABA(B) receptors in the rat ventral tegmental area as measured by baclofen-stimulated 35S-GTPgammaS binding. Life sciences. vol 69. issue 9. 2001-08-30. PMID:11508652. |
this finding may have implications in the augmented extracellular dopamine levels seen in the nucleus accumbens of rats that have been sensitized to cocaine. |
2001-08-30 |
2023-08-12 |
rat |
H C Kim, G Bing, E J Shin, H S Jhoo, M A Cheon, S H Lee, K H Choi, J I Kim, W K Jho. Dextromethorphan affects cocaine-mediated behavioral pattern in parallel with a long-lasting Fos-related antigen-immunoreactivity. Life sciences. vol 69. issue 6. 2001-08-09. PMID:11476183. |
repeated administration with cocaine or dm increased fra-ir in the nucleus accumbens (nac) and striatum which lasted for at least 7 days. |
2001-08-09 |
2023-08-12 |
mouse |
A Zocchi, G Conti, F Orz. Differential effects of cocaine on local cerebral glucose utilization in the mouse and in the rat. Neuroscience letters. vol 306. issue 3. 2001-08-02. PMID:11406324. |
cocaine, according to previous reports, increased glucose utilization in the nucleus accumbens of the rat, while the drug decreased metabolic rates in most of brain areas of both strains of mice. |
2001-08-02 |
2023-08-12 |
mouse |
A Zocchi, G Conti, F Orz. Differential effects of cocaine on local cerebral glucose utilization in the mouse and in the rat. Neuroscience letters. vol 306. issue 3. 2001-08-02. PMID:11406324. |
as the c57 mice are more likely than dba to initiate cocaine self-administration, the effect on the nucleus accumbens support the role of the mesolimbic pathway in mediating the motivational properties of psychostimulants. |
2001-08-02 |
2023-08-12 |
mouse |
A Snyder-Keller, R W Kelle. Spatiotemporal analysis of Fos expression associated with cocaine- and PTZ-induced seizures in prenatally cocaine-treated rats. Experimental neurology. vol 170. issue 1. 2001-08-02. PMID:11421588. |
subconvulsive cocaine doses induced c-fos in cortical areas as well as densely dopamine-innervated regions such as striatum and nucleus accumbens. |
2001-08-02 |
2023-08-12 |
rat |
F Weiss, R Ciccocioppo, L H Parsons, S Katner, X Liu, E P Zorrilla, G R Valdez, O Ben-Shahar, S Angeletti, R R Richte. Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors. Annals of the New York Academy of Sciences. vol 937. 2001-08-02. PMID:11458532. |
considerable evidence exists implicating perturbations in da and 5-ht transmission in the nucleus accumbens--neurochemical systems that are activated by cocaine and ethanol self-administration and deficient during withdrawal--as potential substrates for these affective changes. |
2001-08-02 |
2023-08-12 |
Not clear |
Y Zhang, T M Loonam, P A Noailles, J A Angul. Comparison of cocaine- and methamphetamine-evoked dopamine and glutamate overflow in somatodendritic and terminal field regions of the rat brain during acute, chronic, and early withdrawal conditions. Annals of the New York Academy of Sciences. vol 937. 2001-08-02. PMID:11458542. |
cocaine challenge (early withdrawal) increased glutamate overflow in the caudate putamen and the nucleus accumbens. |
2001-08-02 |
2023-08-12 |
rat |
E M Unterwald, M J Kreek, M Cuntapa. The frequency of cocaine administration impacts cocaine-induced receptor alterations. Brain research. vol 900. issue 1. 2001-07-26. PMID:11325352. |
using receptor autoradiography, twice daily injections of cocaine produced an upregulation of mu opioid receptors in the rostral nucleus accumbens, rostral caudate putamen, and layer i of the rostral cingulate cortex, whereas single daily injections resulted in a significant increase in the nucleus accumbens only. |
2001-07-26 |
2023-08-12 |
rat |
E M Unterwald, M J Kreek, M Cuntapa. The frequency of cocaine administration impacts cocaine-induced receptor alterations. Brain research. vol 900. issue 1. 2001-07-26. PMID:11325352. |
increased dopamine d1 receptor binding was found in the nucleus accumbens and olfactory tubercle following twice daily cocaine injections, but not after single daily injections of the same total daily dose. |
2001-07-26 |
2023-08-12 |
rat |
H L Kimmel, A R Joyce, F I Carroll, M J Kuha. Dopamine D1 and D2 receptors influence dopamine transporter synthesis and degradation in the rat. The Journal of pharmacology and experimental therapeutics. vol 298. issue 1. 2001-07-19. PMID:11408534. |
cocaine increased the half-life of dat in both the striatum and the nucleus accumbens. |
2001-07-19 |
2023-08-12 |
rat |
M Barrot, D N Abrous, M Marinelli, F Rougé-Pont, M Le Moal, P V Piazz. Influence of glucocorticoids on dopaminergic transmission in the rat dorsolateral striatum. The European journal of neuroscience. vol 13. issue 4. 2001-06-28. PMID:11207816. |
the increased dopaminergic response to cocaine also contrasts with the decreased response previously observed in the shell of the nucleus accumbens [barrot et al. |
2001-06-28 |
2023-08-12 |
rat |
E F Schmidt, M A Sutton, C A Schad, D A Karanian, E S Brodkin, D W Sel. Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 7. 2001-06-28. PMID:11264329. |
in this study, 12 d of cocaine self-administration in rats (4 hr/d) reduced th immunoreactivity by 29% in the nucleus accumbens (nac) shell, but not core, after a 1 week withdrawal period. |
2001-06-28 |
2023-08-12 |
rat |
M R Gerasimov, W K Schiffer, E L Gardner, D A Marsteller, I C Lennon, S J Taylor, J D Brodie, C R Ashby, S L Dewe. GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine. European journal of pharmacology. vol 414. issue 2-3. 2001-06-21. PMID:11239920. |
to better understand the neurochemical mechanisms potentially mediating these cues, we measured nucleus accumbens dopamine levels in animals exposed to environmental cues previously paired with cocaine administration. |
2001-06-21 |
2023-08-12 |
Not clear |
K Lutfy, T Do, N T Maidmen. Orphanin FQ/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in rats. Psychopharmacology. vol 154. issue 1. 2001-06-21. PMID:11291998. |
orphanin fq/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in rats. |
2001-06-21 |
2023-08-12 |
rat |
E Carboni, C Spielewoy, C Vacca, M Nosten-Bertrand, B Giros, G Di Chiar. Cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312315. |
cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene. |
2001-06-07 |
2023-08-12 |
mouse |