| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
administration of cocaine into the nucleus accumbens also reinstated drug seeking, whereas microinjection of cocaine into the neostriatum or lateral septum did not. |
2002-04-08 |
2023-08-12 |
human |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
reinstatement of cocaine seeking induced by intra-mpfc cocaine was blocked by administration of the ampa receptor antagonist cnqx into the nucleus accumbens. |
2002-04-08 |
2023-08-12 |
human |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
administration of the nmda receptor antagonist ap-5 into the nucleus accumbens had variable effects on reinstatement induced by intra-mpfc cocaine in that ap-5 had no effect in some animals but augmented reinstatement in others. |
2002-04-08 |
2023-08-12 |
human |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
these data indicate that the glutamatergic pathway from the mpfc to the nucleus accumbens plays an important role in cocaine priming-induced reinstatement of drug seeking. |
2002-04-08 |
2023-08-12 |
human |
| Andrew C Glatz, Michelle Ehrlich, Richard S Bae, Michelle J Clarke, Patricia A Quinlan, Emily C Brown, Pedro Rada, Bartley G Hoebe. Inhibition of cocaine self-administration by fluoxetine or D-fenfluramine combined with phentermine. Pharmacology, biochemistry, and behavior. vol 71. issue 1-2. 2002-04-05. PMID:11812523. |
based on related research with the same dose of d-fen/phen, it is suggested that effectiveness in reducing cocaine reinforcement is due in part to a satiating effect in which dopamine and acetylcholine are released in the nucleus accumbens. |
2002-04-05 |
2023-08-12 |
rat |
| Christina A Schad, Joseph B Justice, Stephen G Holtzma. Endogenous opioids in dopaminergic cell body regions modulate amphetamine-induced increases in extracellular dopamine levels in the terminal regions. The Journal of pharmacology and experimental therapeutics. vol 300. issue 3. 2002-03-28. PMID:11861800. |
opioid antagonists attenuate behavioral effects of amphetamine and amphetamine-induced increases in extracellular dopamine levels in nucleus accumbens and striatum of rats but do not alter those effects of cocaine. |
2002-03-28 |
2023-08-12 |
rat |
| Mika Yamaguchi, Toshihito Suzuki, Shuzo Abe, Atsuomi Baba, Takafumi Hori, Nobuo Okad. Repeated cocaine administration increases GABA(B(1)) subunit mRNA in rat brain. Synapse (New York, N.Y.). vol 43. issue 3. 2002-03-21. PMID:11793422. |
a significant increase in the level of gaba(b(1)) mrna was observed in the nucleus accumbens (11.4%), ca1 field of the hippocampus (16.8%), and thalamus (16.5%) 1 day after repeated administrations of cocaine for 14 consecutive days. |
2002-03-21 |
2023-08-12 |
rat |
| Lynette C Daws, Paul D Callaghan, José A Morón, Kris M Kahlig, Toni S Shippenberg, Jonathan A Javitch, Aurelio Gall. Cocaine increases dopamine uptake and cell surface expression of dopamine transporters. Biochemical and biophysical research communications. vol 290. issue 5. 2002-03-15. PMID:11820798. |
consistent with this novel regulation, [3h]da uptake into synaptosomes prepared from the nucleus accumbens of rats sacrificed 30 min after a single cocaine injection (30 mg/kg) was significantly increased compared to controls (56% increase in v(max), no change in k(m)). |
2002-03-15 |
2023-08-12 |
human |
| K Park, U Vora, S F Darling, M G Kolta, K F Solima. The role of inducible nitric oxide synthase in cocaine-induced locomotor sensitization. Physiology & behavior. vol 74. issue 4-5. 2002-03-07. PMID:11790403. |
dopamine (da) receptor binding in the nucleus accumbens (nac) showed a significant decrease in the density of d(2) receptor and the affinity of d(1) receptor after cocaine treatment. |
2002-03-07 |
2023-08-12 |
rat |
| Y Zhang, S D Schlussman, A Ho, M J Kree. Effect of acute binge cocaine on levels of extracellular dopamine in the caudate putamen and nucleus accumbens in male C57BL/6J and 129/J mice. Brain research. vol 923. issue 1-2. 2002-03-05. PMID:11743985. |
effect of acute binge cocaine on levels of extracellular dopamine in the caudate putamen and nucleus accumbens in male c57bl/6j and 129/j mice. |
2002-03-05 |
2023-08-12 |
mouse |
| Y Zhang, S D Schlussman, A Ho, M J Kree. Effect of acute binge cocaine on levels of extracellular dopamine in the caudate putamen and nucleus accumbens in male C57BL/6J and 129/J mice. Brain research. vol 923. issue 1-2. 2002-03-05. PMID:11743985. |
levels of dopamine, both basal and after binge-pattern cocaine administration, were measured in the caudate putamen and nucleus accumbens of c57bl/6j and 129/j mice by in vivo microdialysis. |
2002-03-05 |
2023-08-12 |
mouse |
| M A F M Gerrits, P Petromilli, H G M Westenberg, G Di Chiara, J M van Re. Decrease in basal dopamine levels in the nucleus accumbens shell during daily drug-seeking behaviour in rats. Brain research. vol 924. issue 2. 2002-03-05. PMID:11750899. |
to study an involvement of accumbal da in drug-seeking behaviour within and between daily self-administration behaviour, changes in extracellular da concentration in the nucleus accumbens (nac) shell were measured during the daily dynamics of intravenous heroin and cocaine self-administration. |
2002-03-05 |
2023-08-12 |
rat |
| J Uslaner, A Badiani, H E Day, S J Watson, H Akil, T E Robinso. Environmental context modulates the ability of cocaine and amphetamine to induce c-fos mRNA expression in the neocortex, caudate nucleus, and nucleus accumbens. Brain research. vol 920. issue 1-2. 2002-02-07. PMID:11716816. |
environmental context modulates the ability of cocaine and amphetamine to induce c-fos mrna expression in the neocortex, caudate nucleus, and nucleus accumbens. |
2002-02-07 |
2023-08-12 |
rat |
| J L Cornish, P W Kaliva. Cocaine sensitization and craving: differing roles for dopamine and glutamate in the nucleus accumbens. Journal of addictive diseases. vol 20. issue 3. 2002-02-01. PMID:11681592. |
cocaine sensitization and craving: differing roles for dopamine and glutamate in the nucleus accumbens. |
2002-02-01 |
2023-08-12 |
Not clear |
| Jose A Morón, Alicia Brockington, Roy A Wise, Beatriz A Rocha, Bruce T Hop. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 2. 2002-01-30. PMID:11784783. |
we have tested this hypothesis by comparing the effects of inhibitors selective for the three monoamine transporters with those of a nonspecific inhibitor, cocaine, on uptake of 3h-dopamine into synaptosomes from frontal cortex, caudate nucleus, and nucleus accumbens from wild-type, net, and dopamine transporter (dat) knock-out mice. |
2002-01-30 |
2023-08-12 |
mouse |
| Jose A Morón, Alicia Brockington, Roy A Wise, Beatriz A Rocha, Bruce T Hop. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 2. 2002-01-30. PMID:11784783. |
cocaine failed to block dopamine uptake into caudate or nucleus accumbens synaptosomes from dat knock-out mice. |
2002-01-30 |
2023-08-12 |
mouse |
| Jose A Morón, Alicia Brockington, Roy A Wise, Beatriz A Rocha, Bruce T Hop. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 2. 2002-01-30. PMID:11784783. |
cocaine and gbr12909 each inhibited dopamine uptake into caudate synaptosomes from net knock-out mice, but cocaine effectiveness was reduced in the case of nucleus accumbens synaptosomes. |
2002-01-30 |
2023-08-12 |
mouse |
| M J Thomas, C Beurrier, A Bonci, R C Malenk. Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine. Nature neuroscience. vol 4. issue 12. 2002-01-11. PMID:11694884. |
long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine. |
2002-01-11 |
2023-08-12 |
Not clear |
| M F Olive, H N Koenig, M A Nannini, C W Hodg. Stimulation of endorphin neurotransmission in the nucleus accumbens by ethanol, cocaine, and amphetamine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 23. 2002-01-11. PMID:11717387. |
stimulation of endorphin neurotransmission in the nucleus accumbens by ethanol, cocaine, and amphetamine. |
2002-01-11 |
2023-08-12 |
rat |
| M F Olive, H N Koenig, M A Nannini, C W Hodg. Stimulation of endorphin neurotransmission in the nucleus accumbens by ethanol, cocaine, and amphetamine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 23. 2002-01-11. PMID:11717387. |
using microdialysis in freely moving rats, we sought to determine whether various drugs of abuse (i.e., ethanol, cocaine, d-amphetamine, and nicotine) would increase neurotransmission of endogenous opioid peptides (i.e., endorphins) in the nucleus accumbens. |
2002-01-11 |
2023-08-12 |
rat |