| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antoinette Y Freeman, R Christopher Pierc. Neutralization of neutrophin-3 in the ventral tegmental area or nucleus accumbens differentially modulates cocaine-induced behavioral plasticity in rats. Synapse (New York, N.Y.). vol 46. issue 2. 2002-11-19. PMID:12211082. |
administration of anti-nt-3 into the nucleus accumbens increased the behavioral response to cocaine over all 4 days of cocaine administration, with no sensitization of this behavioral response. |
2002-11-19 |
2023-08-12 |
rat |
| Antoinette Y Freeman, R Christopher Pierc. Neutralization of neutrophin-3 in the ventral tegmental area or nucleus accumbens differentially modulates cocaine-induced behavioral plasticity in rats. Synapse (New York, N.Y.). vol 46. issue 2. 2002-11-19. PMID:12211082. |
in contrast, pretreatment with anti-bdnf into the vta or nucleus accumbens had no influence on the initiation of behavioral sensitization to cocaine. |
2002-11-19 |
2023-08-12 |
rat |
| Antoinette Y Freeman, R Christopher Pierc. Neutralization of neutrophin-3 in the ventral tegmental area or nucleus accumbens differentially modulates cocaine-induced behavioral plasticity in rats. Synapse (New York, N.Y.). vol 46. issue 2. 2002-11-19. PMID:12211082. |
taken together, these data indicate that neutralization of nt-3 in the vta enhances cocaine-induced behavioral sensitization, while administration of the nt-3 antibody into the nucleus accumbens increases the hyperactive behavioral response induced by cocaine but impairs the further development of behavioral sensitization. |
2002-11-19 |
2023-08-12 |
rat |
| A Eugene Pekary, Shayani Senanayake, Albert Satti. Cocaine regulates TRH-related peptides in rat brain. Neurochemistry international. vol 41. issue 6. 2002-11-12. PMID:12213229. |
trh and leu(2)-trh, decreased 47 and 93%, respectively in the nucleus accumbens (am) while other eep-ir peaks decreased 50-100% consistent with the significant decrease in total eep-ir in the ams following acute cocaine treatment. |
2002-11-12 |
2023-08-12 |
rat |
| Dongsheng Zhang, Lu Zhang, Dan Wen Lou, Yusaku Nakabeppu, Jianhua Zhang, Ming X. The dopamine D1 receptor is a critical mediator for cocaine-induced gene expression. Journal of neurochemistry. vol 82. issue 6. 2002-10-22. PMID:12354293. |
to test this possibility, we systematically compared the expression of the fos and jun family immediate early genes in the nucleus accumbens and caudoputamen in d1 receptor mutant and wild-type control mice after acute and repeated cocaine exposure. |
2002-10-22 |
2023-08-12 |
mouse |
| Regina M Carell. Nucleus accumbens cell firing during goal-directed behaviors for cocaine vs. 'natural' reinforcement. Physiology & behavior. vol 76. issue 3. 2002-10-08. PMID:12117574. |
nucleus accumbens cell firing during goal-directed behaviors for cocaine vs. 'natural' reinforcement. |
2002-10-08 |
2023-08-12 |
rat |
| Regina M Carell. Nucleus accumbens cell firing during goal-directed behaviors for cocaine vs. 'natural' reinforcement. Physiology & behavior. vol 76. issue 3. 2002-10-08. PMID:12117574. |
here, our electrophysiological studies that examined acb cell firing within seconds of lever press responding for intravenous cocaine vs. water or food reinforcement in rats are reviewed. |
2002-10-08 |
2023-08-12 |
rat |
| Regina M Carell. Nucleus accumbens cell firing during goal-directed behaviors for cocaine vs. 'natural' reinforcement. Physiology & behavior. vol 76. issue 3. 2002-10-08. PMID:12117574. |
initial investigations revealed that a subset of acb neurons exhibits four types of firing patterns within seconds of the reinforced response for intravenous cocaine during self-administration sessions. |
2002-10-08 |
2023-08-12 |
rat |
| Regina M Carell. Nucleus accumbens cell firing during goal-directed behaviors for cocaine vs. 'natural' reinforcement. Physiology & behavior. vol 76. issue 3. 2002-10-08. PMID:12117574. |
in a subsequent study, the activity of the same acb neurons was examined in rats responding on multiple schedules for either two distinct 'natural' reinforcers (water and food), or one of those 'natural' reinforcers and the intravenous self-administration of cocaine. |
2002-10-08 |
2023-08-12 |
rat |
| Regina M Carell. Nucleus accumbens cell firing during goal-directed behaviors for cocaine vs. 'natural' reinforcement. Physiology & behavior. vol 76. issue 3. 2002-10-08. PMID:12117574. |
additional studies that examined the role of associative factors on acb cell firing during cocaine self-administration sessions are reviewed. |
2002-10-08 |
2023-08-12 |
rat |
| Istvan Sziráki, Henry Sershen, Audrey Hashim, Abel Lajth. Receptors in the ventral tegmental area mediating nicotine-induced dopamine release in the nucleus accumbens. Neurochemical research. vol 27. issue 3. 2002-10-04. PMID:11958525. |
nicotine or cocaine, when administered intravenously, induces an increase of extracellular dopamine in the nucleus accumbens. |
2002-10-04 |
2023-08-12 |
Not clear |
| Istvan Sziráki, Henry Sershen, Audrey Hashim, Abel Lajth. Receptors in the ventral tegmental area mediating nicotine-induced dopamine release in the nucleus accumbens. Neurochemical research. vol 27. issue 3. 2002-10-04. PMID:11958525. |
we assayed inhibition of the increase of dopamine in the nucleus accumbens induced by intravenous nicotine or cocaine administration by antagonists administered into the ventral tegmental area. |
2002-10-04 |
2023-08-12 |
Not clear |
| Laura Michna, Maria Brenz-Verca, Jean-Luc Dreyer, George C Wagne. Methods to examine molecular changes and behavioral effects of drug administration. Brain research. Brain research protocols. vol 9. issue 3. 2002-09-27. PMID:12113778. |
specifically, cd81 was induced exclusively in the nucleus accumbens by cocaine treatment. |
2002-09-27 |
2023-08-12 |
mouse |
| Jilla Sabeti, Greg A Gerhardt, Nancy R Zahnise. Acute cocaine differentially alters accumbens and striatal dopamine clearance in low and high cocaine locomotor responders: behavioral and electrochemical recordings in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183681. |
the role of the dopamine transporter (dat) in mediating the behavioral differences in cocaine responsiveness in lcrs and hcrs was investigated by high-speed chronoamperometric recording of exogenous dopamine (da) clearance signals in nucleus accumbens (nac) and dorsal striatum (dstr). |
2002-09-18 |
2023-08-12 |
rat |
| Malgorzata Filip, Kathryn A Cunningha. Serotonin 5-HT(2C) receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888566. |
serotonin 5-ht(2c) receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine. |
2002-09-11 |
2023-08-12 |
rat |
| Malgorzata Filip, Kathryn A Cunningha. Serotonin 5-HT(2C) receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888566. |
the serotonin 5-ht(2c) receptor (5-ht(2c)r) is abundant in the nucleus accumbens (nac) shell and is considered an important target for 5-ht to modulate the dopamine (da) mesoaccumbens circuit, which plays a prominent role in the behavioral effects of cocaine. |
2002-09-11 |
2023-08-12 |
rat |
| W Lu, M Marinelli, D Xu, P F Worley, M E Wol. Amphetamine and cocaine do not increase Narp expression in rat ventral tegmental area, nucleus accumbens or prefrontal cortex, but Narp may contribute to individual differences in responding to a novel environment. The European journal of neuroscience. vol 15. issue 12. 2002-09-04. PMID:12099908. |
amphetamine and cocaine do not increase narp expression in rat ventral tegmental area, nucleus accumbens or prefrontal cortex, but narp may contribute to individual differences in responding to a novel environment. |
2002-09-04 |
2023-08-12 |
rat |
| V I Chefer, T S Shippenber. Changes in basal and cocaine-evoked extracellular dopamine uptake and release in the rat nucleus accumbens during early abstinence from cocaine: quantitative determination under transient conditions. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088750. |
changes in basal and cocaine-evoked extracellular dopamine uptake and release in the rat nucleus accumbens during early abstinence from cocaine: quantitative determination under transient conditions. |
2002-09-03 |
2023-08-12 |
rat |
| V I Chefer, T S Shippenber. Changes in basal and cocaine-evoked extracellular dopamine uptake and release in the rat nucleus accumbens during early abstinence from cocaine: quantitative determination under transient conditions. Neuroscience. vol 112. issue 4. 2002-09-03. PMID:12088750. |
these data demonstrate that a cocaine treatment regimen resulting in behavioral sensitization is associated with a reduction in basal dopamine release, an enhancement in both cocaine and k(+)-evoked dopamine release, and a subsensitivity of dopamine d(2) autoreceptors that regulate dopamine release in the nucleus accumbens. |
2002-09-03 |
2023-08-12 |
rat |
| Marcello Solinas, Sergi Ferré, Zhi-Bing You, Marzena Karcz-Kubicha, Patrizia Popoli, Steven R Goldber. Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 15. 2002-09-03. PMID:12151508. |
an increase in the extracellular concentration of dopamine in the nucleus accumbens (nac) is believed to be one of the main mechanisms involved in the rewarding and motor-activating properties of psychostimulants such as amphetamines and cocaine. |
2002-09-03 |
2023-08-12 |
rat |