| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-ht1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. |
2002-08-08 |
2023-08-12 |
rat |
| Corinne Beurrier, Robert C Malenk. Enhanced inhibition of synaptic transmission by dopamine in the nucleus accumbens during behavioral sensitization to cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 14. 2002-08-06. PMID:12122043. |
enhanced inhibition of synaptic transmission by dopamine in the nucleus accumbens during behavioral sensitization to cocaine. |
2002-08-06 |
2023-08-12 |
mouse |
| Jianhua Zhang, Dongsheng Zhang, Ming X. Identification of chronic cocaine-induced gene expression through dopamine d1 receptors by using cDNA microarrays. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105080. |
our initial experiments focused on a target of the mesocorticolimbic da pathway, the nucleus accumbens (nac), which is the primary neural substrate for mediating the long-term effects of cocaine. |
2002-08-02 |
2023-08-12 |
mouse |
| Hiroshi Ujike, Manabu Takaki, Masafumi Kodama, Shigetoshi Kurod. Gene expression related to synaptogenesis, neuritogenesis, and MAP kinase in behavioral sensitization to psychostimulants. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105085. |
previous microscopic studies have shown that the length of dendrites and density of dendritic spines increased in the nucleus accumbens and frontal cortex after repeated exposure to amphetamine and cocaine, but the molecular mechanisms responsible are not well understood. |
2002-08-02 |
2023-08-12 |
Not clear |
| Margery C Beinfeld, Kelly J Connolly, R Christopher Pierc. Cocaine treatment increases extracellular cholecystokinin (CCK) in the nucleus accumbens shell of awake, freely moving rats, an effect that is enhanced in rats that are behaviorally sensitized to cocaine. Journal of neurochemistry. vol 81. issue 5. 2002-07-09. PMID:12065614. |
to better understand its role, cck was measured by microdialysis in the nucleus accumbens (nac) shell in response to cocaine in drug-naive rats and in rats that are behaviorally sensitized to cocaine. |
2002-07-09 |
2023-08-12 |
rat |
| Xu-Feng Zhang, Donald C Cooper, Francis J Whit. Repeated cocaine treatment decreases whole-cell calcium current in rat nucleus accumbens neurons. The Journal of pharmacology and experimental therapeutics. vol 301. issue 3. 2002-06-19. PMID:12023545. |
repeated cocaine treatment decreases whole-cell calcium current in rat nucleus accumbens neurons. |
2002-06-19 |
2023-08-12 |
rat |
| Xu-Feng Zhang, Donald C Cooper, Francis J Whit. Repeated cocaine treatment decreases whole-cell calcium current in rat nucleus accumbens neurons. The Journal of pharmacology and experimental therapeutics. vol 301. issue 3. 2002-06-19. PMID:12023545. |
dopamine d1 receptors within the nucleus accumbens (nac) are intricately involved in the rewarding effects of cocaine and in withdrawal symptoms after cessation of repeated cocaine administration. |
2002-06-19 |
2023-08-12 |
rat |
| Qing Shan Ya. Reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure. Brain research. vol 929. issue 1. 2002-06-12. PMID:11852031. |
reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure. |
2002-06-12 |
2023-08-12 |
rat |
| L Korutla, P J Wang, D M Lewis, J H Neustadter, M F Stromberg, S A Mackle. Differences in expression, actions and cocaine regulation of two isoforms for the brain transcriptional regulator NAC1. Neuroscience. vol 110. issue 3. 2002-06-12. PMID:11906783. |
previous work demonstrated elevated nac1 mrna levels in the rat nucleus accumbens in response to cocaine. |
2002-06-12 |
2023-08-12 |
rat |
| Evgeny A Budygin, Carrie E John, Yolanda Mateo, Sara R Jone. Lack of cocaine effect on dopamine clearance in the core and shell of the nucleus accumbens of dopamine transporter knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 10. 2002-05-29. PMID:12006604. |
lack of cocaine effect on dopamine clearance in the core and shell of the nucleus accumbens of dopamine transporter knock-out mice. |
2002-05-29 |
2023-08-12 |
mouse |
| Evgeny A Budygin, Carrie E John, Yolanda Mateo, Sara R Jone. Lack of cocaine effect on dopamine clearance in the core and shell of the nucleus accumbens of dopamine transporter knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 10. 2002-05-29. PMID:12006604. |
surprisingly, in mice genetically lacking the dat, cocaine was still able to elevate da in the nucleus accumbens (nac). |
2002-05-29 |
2023-08-12 |
mouse |
| M S Todtenkopf, T Carreiras, R H Melloni, J R Stella. The dorsomedial shell of the nucleus accumbens facilitates cocaine-induced locomotor activity during the induction of behavioral sensitization. Behavioural brain research. vol 131. issue 1-2. 2002-05-03. PMID:11844568. |
the data presented here demonstrate that the dorsomedial shell of the nucleus accumbens plays an important role in the initial stages of behavioral sensitization to cocaine. |
2002-05-03 |
2023-08-12 |
Not clear |
| Shridhar Narayanan, Kabirullah Lutfy, Nigel Maidmen. Sensitization to cocaine after a single intra-cerebral injection of orphanin FQ/nociceptin. Behavioural brain research. vol 131. issue 1-2. 2002-05-03. PMID:11844576. |
the administration of ofq/n into the substantia nigra or nucleus accumbens failed to produce a significant sensitized response to a cocaine challenge 24 h later. |
2002-05-03 |
2023-08-12 |
rat |
| Anton N M Schoffelmeer, Taco J De Vries, George Wardeh, Henrica W M van de Ven, Louk J M J Vanderschure. Psychostimulant-induced behavioral sensitization depends on nicotinic receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 8. 2002-04-22. PMID:11943828. |
behavioral sensitization induced by nicotine, amphetamine, or cocaine was associated with an increase in the electrically evoked release of [(3)h]dopamine from nucleus accumbens slices. |
2002-04-22 |
2023-08-12 |
rat |
| Anton N M Schoffelmeer, Taco J De Vries, George Wardeh, Henrica W M van de Ven, Louk J M J Vanderschure. Psychostimulant-induced behavioral sensitization depends on nicotinic receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 8. 2002-04-22. PMID:11943828. |
coadministration of mecamylamine during pretreatment with nicotine, amphetamine, or cocaine prevented the development of this long-term hyperreactivity of nucleus accumbens dopamine neurons. |
2002-04-22 |
2023-08-12 |
rat |
| J L Cornish, P W Kaliva. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2002-04-08. PMID:10899176. |
glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. |
2002-04-08 |
2023-08-12 |
Not clear |
| J L Cornish, P W Kaliva. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2002-04-08. PMID:10899176. |
elevated dopamine transmission in the nucleus accumbens is thought to be a primary mediator of addiction to cocaine. |
2002-04-08 |
2023-08-12 |
Not clear |
| J L Cornish, P W Kaliva. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2002-04-08. PMID:10899176. |
reinstatement was produced by a systemic injection of cocaine or by the microinjection of the glutamate receptor agonist ampa or dopamine into the nucleus accumbens. |
2002-04-08 |
2023-08-12 |
Not clear |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing ampa receptor-mediated glutamate transmission in the nucleus accumbens. |
2002-04-08 |
2023-08-12 |
human |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
we used an animal model of cocaine relapse to determine the role of the glutamatergic pathway from the medial prefrontal cortex (mpfc) to the nucleus accumbens in the reinstatement of cocaine-seeking behavior after a cocaine priming injection. |
2002-04-08 |
2023-08-12 |
human |