| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Ang, J Chen, P Zagouras, H Magna, J Holland, E Schaeffer, E J Nestle. Induction of nuclear factor-kappaB in nucleus accumbens by chronic cocaine administration. Journal of neurochemistry. vol 79. issue 1. 2001-10-25. PMID:11595774. |
these results establish nf-kappab as a putative target for deltafosb and implicate nf-kappab signaling pathways in the long-term adaptations of nucleus accumbens neurons to cocaine. |
2001-10-25 |
2023-08-12 |
mouse |
| P J Fletcher, S R Robinson, D L Slippo. Pre-exposure to (+/-)3,4-methylenedioxy-methamphetamine (MDMA) facilitates acquisition of intravenous cocaine self-administration in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 2. 2001-10-11. PMID:11425503. |
pre-exposure to (+/-)3,4-methylenedioxymeth-amphetamine (mdma) elevates locomotor activity and extracellular dopamine levels in the nucleus accumbens following a cocaine challenge. |
2001-10-11 |
2023-08-12 |
rat |
| J A Crespo, J Manzanares, J M Oliva, J Corchero, T Palomo, E Ambrosi. Extinction of cocaine self-administration produces a differential time-related regulation of proenkephalin gene expression in rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 2. 2001-10-11. PMID:11425502. |
the purpose of this study was to examine the time course effects of extinction of cocaine self-administration behavior on proenkephalin (penk) gene expression in caudate-putamen nucleus (st), nucleus accumbens (acc), olfactory tubercle (tu), piriform cortex (pir), ventromedial hypothalamic nucleus (vmn), and central amygdala (ce) as measured by in situ hybridization histochemistry. |
2001-10-11 |
2023-08-12 |
human |
| R M Carelli, S G Ijame. Selective activation of accumbens neurons by cocaine-associated stimuli during a water/cocaine multiple schedule. Brain research. vol 907. issue 1-2. 2001-10-04. PMID:11430899. |
electrophysiological recording procedures were used to examine the responsiveness of nucleus accumbens (acb) neurons to stimuli associated with cocaine delivery during a multiple schedule for water reinforcement and cocaine self-administration. |
2001-10-04 |
2023-08-12 |
rat |
| R M Carelli, S G Ijame. Selective activation of accumbens neurons by cocaine-associated stimuli during a water/cocaine multiple schedule. Brain research. vol 907. issue 1-2. 2001-10-04. PMID:11430899. |
acb cells were examined in test sessions consisting of 'probe' trials during which the stimulus previously paired with cocaine infusion was randomly presented in a response-independent manner during the self-administration portion of the session. |
2001-10-04 |
2023-08-12 |
rat |
| A M Pliakas, R R Carlson, R L Neve, C Konradi, E J Nestler, W A Carlezo. Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 18. 2001-10-04. PMID:11549750. |
altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated camp response element-binding protein expression in nucleus accumbens. |
2001-10-04 |
2023-08-12 |
rat |
| C Chiamulera, M P Epping-Jordan, A Zocchi, C Marcon, C Cottiny, S Tacconi, M Corsi, F Orzi, F Conque. Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice. Nature neuroscience. vol 4. issue 9. 2001-09-20. PMID:11528416. |
here we show that mice lacking the mglur5 gene do not self-administer cocaine, and show no increased locomotor activity following cocaine treatment, despite showing cocaine-induced increases in nucleus accumbens (nacc) dopamine (da) levels similar to wild-type (wt) mice. |
2001-09-20 |
2023-08-12 |
mouse |
| C N Haile, N Hiroi, E J Nestler, T A Koste. Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats. Synapse (New York, N.Y.). vol 41. issue 3. 2001-09-13. PMID:11391778. |
we investigated locomotor activity, stereotypy signs, and levels of specific proteins in the nucleus accumbens (nac) and ventral tegmental area (vta) in these strains at baseline and following chronic administration of cocaine (30 mg/kg/day for 14 days). |
2001-09-13 |
2023-08-12 |
rat |
| Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. |
2001-08-30 |
2023-08-12 |
Not clear |
| Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
in vivo voltammetry was used to investigate the preferential increase of extracellular dopamine in the nucleus accumbens relative to the caudate-putamen after systemic cocaine administration. |
2001-08-30 |
2023-08-12 |
Not clear |
| Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
all three drugs robustly increased electrically evoked levels of dopamine, and cocaine elevated dopamine signals to a greater extent in the nucleus accumbens. |
2001-08-30 |
2023-08-12 |
Not clear |
| Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
under the present in vivo conditions, therefore, cocaine is a competitive inhibitor of dopamine uptake in both the nucleus accumbens and caudate-putamen. |
2001-08-30 |
2023-08-12 |
Not clear |
| Q Wu, M E Reith, M J Kuhar, F I Carroll, P A Garri. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487657. |
the lower rates for dopamine release and uptake measured in the nucleus accumbens were found to underlie the preferential increase in extracellular dopamine after cocaine. |
2001-08-30 |
2023-08-12 |
Not clear |
| S A Kushner, E M Unterwal. Chronic cocaine administration decreases the functional coupling of GABA(B) receptors in the rat ventral tegmental area as measured by baclofen-stimulated 35S-GTPgammaS binding. Life sciences. vol 69. issue 9. 2001-08-30. PMID:11508652. |
this finding may have implications in the augmented extracellular dopamine levels seen in the nucleus accumbens of rats that have been sensitized to cocaine. |
2001-08-30 |
2023-08-12 |
rat |
| H C Kim, G Bing, E J Shin, H S Jhoo, M A Cheon, S H Lee, K H Choi, J I Kim, W K Jho. Dextromethorphan affects cocaine-mediated behavioral pattern in parallel with a long-lasting Fos-related antigen-immunoreactivity. Life sciences. vol 69. issue 6. 2001-08-09. PMID:11476183. |
repeated administration with cocaine or dm increased fra-ir in the nucleus accumbens (nac) and striatum which lasted for at least 7 days. |
2001-08-09 |
2023-08-12 |
mouse |
| A Zocchi, G Conti, F Orz. Differential effects of cocaine on local cerebral glucose utilization in the mouse and in the rat. Neuroscience letters. vol 306. issue 3. 2001-08-02. PMID:11406324. |
cocaine, according to previous reports, increased glucose utilization in the nucleus accumbens of the rat, while the drug decreased metabolic rates in most of brain areas of both strains of mice. |
2001-08-02 |
2023-08-12 |
mouse |
| A Zocchi, G Conti, F Orz. Differential effects of cocaine on local cerebral glucose utilization in the mouse and in the rat. Neuroscience letters. vol 306. issue 3. 2001-08-02. PMID:11406324. |
as the c57 mice are more likely than dba to initiate cocaine self-administration, the effect on the nucleus accumbens support the role of the mesolimbic pathway in mediating the motivational properties of psychostimulants. |
2001-08-02 |
2023-08-12 |
mouse |
| A Snyder-Keller, R W Kelle. Spatiotemporal analysis of Fos expression associated with cocaine- and PTZ-induced seizures in prenatally cocaine-treated rats. Experimental neurology. vol 170. issue 1. 2001-08-02. PMID:11421588. |
subconvulsive cocaine doses induced c-fos in cortical areas as well as densely dopamine-innervated regions such as striatum and nucleus accumbens. |
2001-08-02 |
2023-08-12 |
rat |
| F Weiss, R Ciccocioppo, L H Parsons, S Katner, X Liu, E P Zorrilla, G R Valdez, O Ben-Shahar, S Angeletti, R R Richte. Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors. Annals of the New York Academy of Sciences. vol 937. 2001-08-02. PMID:11458532. |
considerable evidence exists implicating perturbations in da and 5-ht transmission in the nucleus accumbens--neurochemical systems that are activated by cocaine and ethanol self-administration and deficient during withdrawal--as potential substrates for these affective changes. |
2001-08-02 |
2023-08-12 |
Not clear |
| Y Zhang, T M Loonam, P A Noailles, J A Angul. Comparison of cocaine- and methamphetamine-evoked dopamine and glutamate overflow in somatodendritic and terminal field regions of the rat brain during acute, chronic, and early withdrawal conditions. Annals of the New York Academy of Sciences. vol 937. 2001-08-02. PMID:11458542. |
cocaine challenge (early withdrawal) increased glutamate overflow in the caudate putamen and the nucleus accumbens. |
2001-08-02 |
2023-08-12 |
rat |