| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J S Meyer, I Shani, D Ric. Effects of neonatal cocaine treatment and gender on opioid agonist-stimulated [(35)S]GTP gamma S binding in the striatum and nucleus accumbens. Brain research bulletin. vol 53. issue 2. 2000-12-07. PMID:11044590. |
effects of neonatal cocaine treatment and gender on opioid agonist-stimulated [(35)s]gtp gamma s binding in the striatum and nucleus accumbens. |
2000-12-07 |
2023-08-12 |
rat |
| G M Sizemore, C Co, J E Smit. Ventral pallidal extracellular fluid levels of dopamine, serotonin, gamma amino butyric acid, and glutamate during cocaine self-administration in rats. Psychopharmacology. vol 150. issue 4. 2000-11-30. PMID:10958080. |
dopamine innervation of the nucleus accumbens is thought to have a major role in the biological processes underlying cocaine self-administration. |
2000-11-30 |
2023-08-12 |
rat |
| M S Todtenkopf, J R Stella. Assessment of tyrosine hydroxylase immunoreactive innervation in five subregions of the nucleus accumbens shell in rats treated with repeated cocaine. Synapse (New York, N.Y.). vol 38. issue 3. 2000-11-28. PMID:11020229. |
to explore the effects of behavioral sensitization on the anatomy of the nucleus accumbens shell, we employed a typical cocaine dosing paradigm and assessed tyrosine hydroxylase immunoreactive varicosities in five different areas of the shell, as well as the core of the nucleus accumbens. |
2000-11-28 |
2023-08-12 |
rat |
| J M Loftis, A Janowsk. Regulation of NMDA receptor subunits and nitric oxide synthase expression during cocaine withdrawal. Journal of neurochemistry. vol 75. issue 5. 2000-11-09. PMID:11032893. |
two weeks of withdrawal from cocaine caused an approximately 50% increase in nr2b subunit expression in regions of the cortex, neostriatum, and nucleus accumbens. |
2000-11-09 |
2023-08-12 |
rat |
| R M Liao, Y H Chang, S H Wang, C H La. Distinct accumbal subareas are involved in place conditioning of amphetamine and cocaine. Life sciences. vol 67. issue 17. 2000-11-09. PMID:11057753. |
in considering the heterogeneous function of the nucleus accumbens (nac), the present work evaluated the conditioned place preference (cpp) after local infusion of d-amphetamine (amp; 10, 15 microg/side) or cocaine (coc; 50, 100 microg/side) into two subareas of nac, core and shell. |
2000-11-09 |
2023-08-12 |
Not clear |
| K Brebner, R Phelan, D C Robert. Intra-VTA baclofen attenuates cocaine self-administration on a progressive ratio schedule of reinforcement. Pharmacology, biochemistry, and behavior. vol 66. issue 4. 2000-11-07. PMID:10973526. |
intra-vta baclofen produced the most potent modulation of cocaine intake, causing a significant reduction in cocaine-reinforced break points at a dose (56 ng/side) that was substantially lower than doses necessary to produce comparable reductions in the nucleus accumbens or striatum. |
2000-11-07 |
2023-08-12 |
rat |
| J Y Chang, P H Janak, D J Woodwar. Neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. Neuroscience. vol 99. issue 3. 2000-11-07. PMID:11029536. |
neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. |
2000-11-07 |
2023-08-12 |
rat |
| J Y Chang, P H Janak, D J Woodwar. Neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. Neuroscience. vol 99. issue 3. 2000-11-07. PMID:11029536. |
because this circuit is hypothesized to drive drug-seeking behavior, we suggest that this correlated firing between the nucleus accumbens and the medial prefrontal cortex may participate in the control of cocaine self-administration. |
2000-11-07 |
2023-08-12 |
rat |
| J Y Chang, P H Janak, D J Woodwar. Neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. Neuroscience. vol 99. issue 3. 2000-11-07. PMID:11029536. |
in addition, the finding that correlated activity within the nucleus accumbens more often precedes that of the medial prefrontal cortex suggests that the nucleus accumbens may play a prime role in the initiation of cocaine self-administration. |
2000-11-07 |
2023-08-12 |
rat |
| K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. |
three weeks following the last daily injection dialysis probes were placed into the nucleus accumbens and all rats were injected with saline followed by cocaine. |
2000-10-11 |
2023-08-12 |
rat |
| K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. |
in this study it was found that the motor stimulant response elicited by cocaine was blunted by pretreatment of the nucleus accumbens with 6-cyano-7-nitroquinoxaline-2,3-dione only in animals receiving daily cocaine injections in the paired environment. |
2000-10-11 |
2023-08-12 |
rat |
| K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. |
these data support a hypothesis that environmental stimuli previously associated with daily cocaine administration can modulate glutamate transmission in the nucleus accumbens in a manner affecting cocaine-induced behavior. |
2000-10-11 |
2023-08-12 |
rat |
| K K Szumlinski, I M Maisonneuve, S D Glic. Differential effects of ibogaine on behavioural and dopamine sensitization to cocaine. European journal of pharmacology. vol 398. issue 2. 2000-10-05. PMID:10854838. |
however, while ibogaine pretreatment did not significantly alter the dopamine response in the nucleus accumbens to acute cocaine, it abolished the expression of cocaine-induced dopamine sensitization. |
2000-10-05 |
2023-08-12 |
rat |
| E A Kiyatkin, D E Kiyatkin, G V Rebe. Phasic inhibition of dopamine uptake in nucleus accumbens induced by intravenous cocaine in freely behaving rats. Neuroscience. vol 98. issue 4. 2000-09-27. PMID:10891616. |
phasic inhibition of dopamine uptake in nucleus accumbens induced by intravenous cocaine in freely behaving rats. |
2000-09-27 |
2023-08-12 |
rat |
| E A Kiyatkin, D E Kiyatkin, G V Rebe. Phasic inhibition of dopamine uptake in nucleus accumbens induced by intravenous cocaine in freely behaving rats. Neuroscience. vol 98. issue 4. 2000-09-27. PMID:10891616. |
a new approach combining fast-scan cyclic voltammetry with iontophoretic dopamine delivery was used in freely behaving rats to evaluate the time-course of dopamine uptake inhibition in nucleus accumbens induced by intravenous cocaine at a dose (1.0mg/kg) known to maintain self-administration behavior. |
2000-09-27 |
2023-08-12 |
rat |
| A Rosin, I van der Ploeg, J Georgiev. Basal and cocaine-induced opioid receptor gene expression in the rat CNS analyzed by competitive reverse transcription PCR. Brain research. vol 872. issue 1-2. 2000-09-20. PMID:10924681. |
the data suggest a selective effect on kappa receptor expression in the nucleus accumbens as a consequence of 'binge' cocaine use. |
2000-09-20 |
2023-08-12 |
rat |
| M S Todtenkopf, K R De Leon, J R Stella. Repeated cocaine treatment alters tyrosine hydroxylase in the rat nucleus accumbens. Brain research bulletin. vol 52. issue 5. 2000-09-14. PMID:10922520. |
repeated cocaine treatment alters tyrosine hydroxylase in the rat nucleus accumbens. |
2000-09-14 |
2023-08-12 |
rat |
| M R Gerasimov, W K Schiffer, J D Brodie, I C Lennon, S J Taylor, S L Dewe. gamma-aminobutyric acid mimetic drugs differentially inhibit the dopaminergic response to cocaine. European journal of pharmacology. vol 395. issue 2. 2000-09-06. PMID:10794818. |
we previously demonstrated that increased gamma-aminobutyric acid (gaba)-ergic activity produced by gamma-vinyl gaba [d,l-4-amino-hex-5-enoic acid (vigabatrin(r))], an irreversible inhibitor of gaba-transaminase, attenuated cocaine, nicotine, heroin, alcohol, and methamphetamine-induced increases in extracellular nucleus accumbens dopamine as well as behaviors associated with these biochemical changes. |
2000-09-06 |
2023-08-12 |
Not clear |
| S A Mackler, L Korutla, X Y Cha, M J Koebbe, K M Fournier, M S Bowers, P W Kaliva. NAC-1 is a brain POZ/BTB protein that can prevent cocaine-induced sensitization in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 16. 2000-08-31. PMID:10934270. |
adenoviral-mediated overexpression of nac-1 protein in the rat nucleus accumbens prevented the development but not the expression of behavioral sensitization produced by repeated administration of cocaine. |
2000-08-31 |
2023-08-12 |
rat |
| T N Ferraro, G T Golden, W H Berrettini, E Gottheil, C H Yang, G R Cuppels, W H Voge. Cocaine intake by rats correlates with cocaine-induced dopamine changes in the nucleus accumbens shell. Pharmacology, biochemistry, and behavior. vol 66. issue 2. 2000-08-28. PMID:10880696. |
extracellular dopamine levels were determined by microdialysis in the core and shell of the nucleus accumbens and the frontal cortex of rats before and after an injection of cocaine (20 mg/kg, ip). |
2000-08-28 |
2023-08-12 |
rat |