| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y L Hurd, M Ponté. Cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. Behavioural brain research. vol 116. issue 2. 2001-02-02. PMID:11080549. |
cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. |
2001-02-02 |
2023-08-12 |
rat |
| Y L Hurd, M Ponté. Cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. Behavioural brain research. vol 116. issue 2. 2001-02-02. PMID:11080549. |
in the present study, the in vivo microdialysis technique was used to directly manipulate extracellular dopamine concentrations in the nucleus accumbens (nac) shell and the amygdala (amy) in rats maintaining stable patterns of cocaine (1.5 mg/kg/infusion) intake under a fixed ratio 1 schedule of reinforcement. |
2001-02-02 |
2023-08-12 |
rat |
| Y L Hurd, M Ponté. Cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. Behavioural brain research. vol 116. issue 2. 2001-02-02. PMID:11080549. |
other perfusate concentrations tested, 180 and 360 nm, in both the nucleus accumbens and amygdala, were without effect on altering the stable pattern of cocaine self-administration behavior. |
2001-02-02 |
2023-08-12 |
rat |
| H Morikawa, O J Manzoni, J C Crabbe, J T William. Regulation of central synaptic transmission by 5-HT(1B) auto- and heteroreceptors. Molecular pharmacology. vol 58. issue 6. 2001-01-18. PMID:11093763. |
finally, cocaine, which blocks 5-ht uptake, inhibited ipsps in the dorsal raphe and the ventral midbrain of wild-type but not knockout mice, whereas cocaine produced comparable inhibition of excitatory postsynaptic currents in the nucleus accumbens of both types of animals. |
2001-01-18 |
2023-08-12 |
mouse |
| N H Mutschler, K A Miczek, R P Hamme. Reduction of zif268 messenger RNA expression during prolonged withdrawal following "binge" cocaine self-administration in rats. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098116. |
following a prolonged cocaine self-administration binge, dopamine efflux in the nucleus accumbens is attenuated and behaviors emerge that are indicative of anhedonia and anxiety. |
2001-01-11 |
2023-08-12 |
rat |
| N H Mutschler, K A Miczek, R P Hamme. Reduction of zif268 messenger RNA expression during prolonged withdrawal following "binge" cocaine self-administration in rats. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098116. |
the results suggest that withdrawal following a cocaine self-administration binge produces a long-lasting reduction of constitutive zif268 messenger rna expression in mesocorticolimbic brain regions related to the nucleus accumbens. |
2001-01-11 |
2023-08-12 |
rat |
| R M Carelli, S Ijames, J Konstantopoulos, S A Deadwyle. Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. Behavioural brain research. vol 104. issue 1-2. 2001-01-11. PMID:11125731. |
examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. |
2001-01-11 |
2023-08-12 |
rat |
| R M Carelli, S Ijames, J Konstantopoulos, S A Deadwyle. Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. Behavioural brain research. vol 104. issue 1-2. 2001-01-11. PMID:11125731. |
we have previously reported that at the initiation of cocaine self-administration sessions, neurons in the nucleus accumbens (na) exhibit a spontaneous transition in firing rate from activity unrelated to the reinforced response, to one of four types of patterned discharges (carelli rm, king vc, hampson re, deadwyler sa. |
2001-01-11 |
2023-08-12 |
rat |
| R M Carelli, S Ijames, J Konstantopoulos, S A Deadwyle. Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. Behavioural brain research. vol 104. issue 1-2. 2001-01-11. PMID:11125731. |
firing patterns of nucleus accumbens neurons during cocaine self-administration in rats. |
2001-01-11 |
2023-08-12 |
rat |
| R M Carelli, S Ijames, J Konstantopoulos, S A Deadwyle. Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. Behavioural brain research. vol 104. issue 1-2. 2001-01-11. PMID:11125731. |
dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. |
2001-01-11 |
2023-08-12 |
rat |
| S R Howes, J W Dalley, C H Morrison, T W Robbins, B J Everit. Leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal FOS expression. Psychopharmacology. vol 151. issue 1. 2000-12-28. PMID:10958117. |
leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal fos expression. |
2000-12-28 |
2023-08-12 |
rat |
| M R Gerasimov, M Franceschi, N D Volkow, O Rice, W K Schiffer, S L Dewe. Synergistic interactions between nicotine and cocaine or methylphenidate depend on the dose of dopamine transporter inhibitor. Synapse (New York, N.Y.). vol 38. issue 4. 2000-12-14. PMID:11044890. |
it is thought that the reinforcing effects of cocaine and mp are due partly to increases in synaptic da in the nucleus accumbens (nac). |
2000-12-14 |
2023-08-12 |
Not clear |
| J S Meyer, I Shani, D Ric. Effects of neonatal cocaine treatment and gender on opioid agonist-stimulated [(35)S]GTP gamma S binding in the striatum and nucleus accumbens. Brain research bulletin. vol 53. issue 2. 2000-12-07. PMID:11044590. |
effects of neonatal cocaine treatment and gender on opioid agonist-stimulated [(35)s]gtp gamma s binding in the striatum and nucleus accumbens. |
2000-12-07 |
2023-08-12 |
rat |
| G M Sizemore, C Co, J E Smit. Ventral pallidal extracellular fluid levels of dopamine, serotonin, gamma amino butyric acid, and glutamate during cocaine self-administration in rats. Psychopharmacology. vol 150. issue 4. 2000-11-30. PMID:10958080. |
dopamine innervation of the nucleus accumbens is thought to have a major role in the biological processes underlying cocaine self-administration. |
2000-11-30 |
2023-08-12 |
rat |
| M S Todtenkopf, J R Stella. Assessment of tyrosine hydroxylase immunoreactive innervation in five subregions of the nucleus accumbens shell in rats treated with repeated cocaine. Synapse (New York, N.Y.). vol 38. issue 3. 2000-11-28. PMID:11020229. |
to explore the effects of behavioral sensitization on the anatomy of the nucleus accumbens shell, we employed a typical cocaine dosing paradigm and assessed tyrosine hydroxylase immunoreactive varicosities in five different areas of the shell, as well as the core of the nucleus accumbens. |
2000-11-28 |
2023-08-12 |
rat |
| J M Loftis, A Janowsk. Regulation of NMDA receptor subunits and nitric oxide synthase expression during cocaine withdrawal. Journal of neurochemistry. vol 75. issue 5. 2000-11-09. PMID:11032893. |
two weeks of withdrawal from cocaine caused an approximately 50% increase in nr2b subunit expression in regions of the cortex, neostriatum, and nucleus accumbens. |
2000-11-09 |
2023-08-12 |
rat |
| R M Liao, Y H Chang, S H Wang, C H La. Distinct accumbal subareas are involved in place conditioning of amphetamine and cocaine. Life sciences. vol 67. issue 17. 2000-11-09. PMID:11057753. |
in considering the heterogeneous function of the nucleus accumbens (nac), the present work evaluated the conditioned place preference (cpp) after local infusion of d-amphetamine (amp; 10, 15 microg/side) or cocaine (coc; 50, 100 microg/side) into two subareas of nac, core and shell. |
2000-11-09 |
2023-08-12 |
Not clear |
| K Brebner, R Phelan, D C Robert. Intra-VTA baclofen attenuates cocaine self-administration on a progressive ratio schedule of reinforcement. Pharmacology, biochemistry, and behavior. vol 66. issue 4. 2000-11-07. PMID:10973526. |
intra-vta baclofen produced the most potent modulation of cocaine intake, causing a significant reduction in cocaine-reinforced break points at a dose (56 ng/side) that was substantially lower than doses necessary to produce comparable reductions in the nucleus accumbens or striatum. |
2000-11-07 |
2023-08-12 |
rat |
| J Y Chang, P H Janak, D J Woodwar. Neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. Neuroscience. vol 99. issue 3. 2000-11-07. PMID:11029536. |
neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. |
2000-11-07 |
2023-08-12 |
rat |
| J Y Chang, P H Janak, D J Woodwar. Neuronal and behavioral correlations in the medial prefrontal cortex and nucleus accumbens during cocaine self-administration by rats. Neuroscience. vol 99. issue 3. 2000-11-07. PMID:11029536. |
because this circuit is hypothesized to drive drug-seeking behavior, we suggest that this correlated firing between the nucleus accumbens and the medial prefrontal cortex may participate in the control of cocaine self-administration. |
2000-11-07 |
2023-08-12 |
rat |