| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Filip, M L Thomas, K A Cunningha. Dopamine D5 receptors in nucleus accumbens contribute to the detection of cocaine in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 19. 2001-02-22. PMID:11000198. |
dopamine d5 receptors in nucleus accumbens contribute to the detection of cocaine in rats. |
2001-02-22 |
2023-08-12 |
rat |
| R Ito, J W Dalley, S R Howes, T W Robbins, B J Everit. Dissociation in conditioned dopamine release in the nucleus accumbens core and shell in response to cocaine cues and during cocaine-seeking behavior in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 19. 2001-02-22. PMID:11007908. |
results showed the following: (1) nucleus accumbens da increased in both the core and shell during intravenous cocaine self-administration; (2) noncontingent presentations of a cocaine-associated cs+ led to increased da release selectively in the nucleus accumbens core; and (3) extracellular da levels were unaltered in both core and shell during a protracted period of drug-seeking behavior under the control of the same cocaine-associated cue. |
2001-02-22 |
2023-08-12 |
rat |
| A C Thompson, A Zapata, J B Justice, R A Vaughan, L G Sharpe, T S Shippenber. Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 24. 2001-02-22. PMID:11125013. |
kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine. |
2001-02-22 |
2023-08-12 |
rat |
| A C Thompson, A Zapata, J B Justice, R A Vaughan, L G Sharpe, T S Shippenber. Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 24. 2001-02-22. PMID:11125013. |
coadministration of kappa-opioid receptor agonists (kappa-agonists) with cocaine prevents alterations in dialysate dopamine (da) concentration in the nucleus accumbens (acb) that occur during abstinence from repeated cocaine treatment. |
2001-02-22 |
2023-08-12 |
rat |
| A C Thompson, A Zapata, J B Justice, R A Vaughan, L G Sharpe, T S Shippenber. Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 24. 2001-02-22. PMID:11125013. |
these results demonstrate that kappa-opioid receptor activation modulates da uptake in the acb in a manner opposite to that of cocaine: repeated u-69593 administration decreases the basal rate of da uptake, and acute u-69593 administration transiently increases da uptake. |
2001-02-22 |
2023-08-12 |
rat |
| M Arroyo, W A Baker, B J Everit. Cocaine self-administration in rats differentially alters mRNA levels of the monoamine transporters and striatal neuropeptides. Brain research. Molecular brain research. vol 83. issue 1-2. 2001-02-15. PMID:11072100. |
in addition, the expression of the striatal neuropeptides was also differentially altered; substance p mrna levels were transiently increased in the shell of the nucleus accumbens by prolonged cocaine self-administration, but enkephalin mrna levels in the dorsal and ventral striatum remained unaltered under all conditions. |
2001-02-15 |
2023-08-12 |
rat |
| M Barrot, M C Rettori, B Guardiola-Lemaître, C Jarry, M Le Moal, P V Piazz. Interactions between imidazoline binding sites and dopamine levels in the rat nucleus accumbens. The European journal of neuroscience. vol 12. issue 12. 2001-02-15. PMID:11122366. |
s23229 had a stronger efficacy than s23230 and increased dopamine levels in the nucleus accumbens at an extent similar to the one of cocaine. |
2001-02-15 |
2023-08-12 |
rat |
| K K Szumlinski, I M Maisonneuve, S D Glic. Iboga interactions with psychomotor stimulants: panacea in the paradox? Toxicon : official journal of the International Society on Toxinology. vol 39. issue 1. 2001-02-02. PMID:10936624. |
however, this interpretation is contradicted by very recent observations that 18-mc is without effect on the dopamine response to acute cocaine and that both ibogaine and 18-mc block the expression of sensitized levels of dopamine in the nucleus accumbens produced by chronic cocaine administration. |
2001-02-02 |
2023-08-12 |
Not clear |
| Y L Hurd, M Ponté. Cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. Behavioural brain research. vol 116. issue 2. 2001-02-02. PMID:11080549. |
cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. |
2001-02-02 |
2023-08-12 |
rat |
| Y L Hurd, M Ponté. Cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. Behavioural brain research. vol 116. issue 2. 2001-02-02. PMID:11080549. |
in the present study, the in vivo microdialysis technique was used to directly manipulate extracellular dopamine concentrations in the nucleus accumbens (nac) shell and the amygdala (amy) in rats maintaining stable patterns of cocaine (1.5 mg/kg/infusion) intake under a fixed ratio 1 schedule of reinforcement. |
2001-02-02 |
2023-08-12 |
rat |
| Y L Hurd, M Ponté. Cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. Behavioural brain research. vol 116. issue 2. 2001-02-02. PMID:11080549. |
other perfusate concentrations tested, 180 and 360 nm, in both the nucleus accumbens and amygdala, were without effect on altering the stable pattern of cocaine self-administration behavior. |
2001-02-02 |
2023-08-12 |
rat |
| H Morikawa, O J Manzoni, J C Crabbe, J T William. Regulation of central synaptic transmission by 5-HT(1B) auto- and heteroreceptors. Molecular pharmacology. vol 58. issue 6. 2001-01-18. PMID:11093763. |
finally, cocaine, which blocks 5-ht uptake, inhibited ipsps in the dorsal raphe and the ventral midbrain of wild-type but not knockout mice, whereas cocaine produced comparable inhibition of excitatory postsynaptic currents in the nucleus accumbens of both types of animals. |
2001-01-18 |
2023-08-12 |
mouse |
| N H Mutschler, K A Miczek, R P Hamme. Reduction of zif268 messenger RNA expression during prolonged withdrawal following "binge" cocaine self-administration in rats. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098116. |
following a prolonged cocaine self-administration binge, dopamine efflux in the nucleus accumbens is attenuated and behaviors emerge that are indicative of anhedonia and anxiety. |
2001-01-11 |
2023-08-12 |
rat |
| N H Mutschler, K A Miczek, R P Hamme. Reduction of zif268 messenger RNA expression during prolonged withdrawal following "binge" cocaine self-administration in rats. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098116. |
the results suggest that withdrawal following a cocaine self-administration binge produces a long-lasting reduction of constitutive zif268 messenger rna expression in mesocorticolimbic brain regions related to the nucleus accumbens. |
2001-01-11 |
2023-08-12 |
rat |
| R M Carelli, S Ijames, J Konstantopoulos, S A Deadwyle. Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. Behavioural brain research. vol 104. issue 1-2. 2001-01-11. PMID:11125731. |
examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. |
2001-01-11 |
2023-08-12 |
rat |
| R M Carelli, S Ijames, J Konstantopoulos, S A Deadwyle. Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. Behavioural brain research. vol 104. issue 1-2. 2001-01-11. PMID:11125731. |
we have previously reported that at the initiation of cocaine self-administration sessions, neurons in the nucleus accumbens (na) exhibit a spontaneous transition in firing rate from activity unrelated to the reinforced response, to one of four types of patterned discharges (carelli rm, king vc, hampson re, deadwyler sa. |
2001-01-11 |
2023-08-12 |
rat |
| R M Carelli, S Ijames, J Konstantopoulos, S A Deadwyle. Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. Behavioural brain research. vol 104. issue 1-2. 2001-01-11. PMID:11125731. |
firing patterns of nucleus accumbens neurons during cocaine self-administration in rats. |
2001-01-11 |
2023-08-12 |
rat |
| R M Carelli, S Ijames, J Konstantopoulos, S A Deadwyle. Examination of factors mediating the transition to behaviorally correlated nucleus accumbens cell firing during cocaine self-administration sessions in rats. Behavioural brain research. vol 104. issue 1-2. 2001-01-11. PMID:11125731. |
dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. |
2001-01-11 |
2023-08-12 |
rat |
| S R Howes, J W Dalley, C H Morrison, T W Robbins, B J Everit. Leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal FOS expression. Psychopharmacology. vol 151. issue 1. 2000-12-28. PMID:10958117. |
leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal fos expression. |
2000-12-28 |
2023-08-12 |
rat |
| M R Gerasimov, M Franceschi, N D Volkow, O Rice, W K Schiffer, S L Dewe. Synergistic interactions between nicotine and cocaine or methylphenidate depend on the dose of dopamine transporter inhibitor. Synapse (New York, N.Y.). vol 38. issue 4. 2000-12-14. PMID:11044890. |
it is thought that the reinforcing effects of cocaine and mp are due partly to increases in synaptic da in the nucleus accumbens (nac). |
2000-12-14 |
2023-08-12 |
Not clear |