| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Małgorzata Frankowska, Karolina Wydra, Agata Faron-Górecka, Magdalena Zaniewska, Maciej Kuśmider, Marta Dziedzicka-Wasylewska, Małgorzata Fili. Alterations in gamma-aminobutyric acid(B) receptor binding in the rat brain after reinstatement of cocaine-seeking behavior. Pharmacological reports : PR. vol 60. issue 6. 2009-04-23. PMID:19211975. |
the binding of [(3)h]cgp 54626 in the nucleus accumbens and the amygdaloid complex was decreased by about 20% in rats that actively administered cocaine. |
2009-04-23 |
2023-08-12 |
rat |
| George A Rogge, Douglas C Jones, Thomas Green, Eric Nestler, Michael J Kuha. Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo. Brain research. vol 1251. 2009-04-20. PMID:19046951. |
production of mrna from the cocaine- and amphetamine-regulated transcript (cart) gene is regulated by cocaine and other drugs of abuse in the nucleus accumbens (nac), a brain reward region. |
2009-04-20 |
2023-08-12 |
rat |
| Armina T Wiggins, Alejandra M Pacchioni, Peter W Kaliva. Integrin expression is altered after acute and chronic cocaine. Neuroscience letters. vol 450. issue 3. 2009-04-20. PMID:19073234. |
cocaine addiction is associated with an increase in actin cycling and alterations in dendritic spines in the nucleus accumbens. |
2009-04-20 |
2023-08-12 |
mouse |
| Armina T Wiggins, Alejandra M Pacchioni, Peter W Kaliva. Integrin expression is altered after acute and chronic cocaine. Neuroscience letters. vol 450. issue 3. 2009-04-20. PMID:19073234. |
after 3 weeks of withdrawal, the level of beta-integrins in the postsynaptic density enriched subfraction from nucleus accumbens tissue was quantified by immunoblotting at 0, 30 or 120min following an a cocaine challenge injection. |
2009-04-20 |
2023-08-12 |
mouse |
| Tao Li, Chun-Xia Yan, Ying Hou, Wei Cao, Teng Chen, Bo-Feng Zhu, Sheng-Bing L. Cue-elicited drug craving represses ERK activation in mice prefrontal association cortex. Neuroscience letters. vol 448. issue 1. 2009-04-16. PMID:18940233. |
in the accumbens nucleus (acb) and caudate putamen (cpu) that are associated with cocaine addiction, the activities of erk1 and erk2 among four groups showed no difference. |
2009-04-16 |
2023-08-12 |
mouse |
| Giovanni Hernandez, Eric Haines, Peter Shizga. Potentiation of intracranial self-stimulation during prolonged subcutaneous infusion of cocaine. Journal of neuroscience methods. vol 175. issue 1. 2009-04-09. PMID:18765253. |
in the first, changes in dopamine tone in the nucleus accumbens were measured by means of microdialysis during prolonged subcutaneous infusions of cocaine. |
2009-04-09 |
2023-08-12 |
Not clear |
| Olga D Taraschenko, Heather Y Rubbinaccio, Isabelle M Maisonneuve, Stanley D Glic. 18-methoxycoronaridine: a potential new treatment for obesity in rats? Psychopharmacology. vol 201. issue 3. 2009-04-07. PMID:18751969. |
since 18-methoxycoronaridine (18-mc), a selective antagonist of alpha3beta4 nicotinic receptors, was previously shown to alter dopamine release in the nucleus accumbens in response to chronic injections of cocaine and morphine, this drug could be a promising therapy for abnormal eating behavior. |
2009-04-07 |
2023-08-12 |
rat |
| Rajani Maiya, Yan Zhou, Erin H Norris, Mary Jeanne Kreek, Sidney Stricklan. Tissue plasminogen activator modulates the cellular and behavioral response to cocaine. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 6. 2009-03-10. PMID:19181855. |
compared with wt mice, tpa-/- mice injected with cocaine displayed attenuated phosphorylation of erk, camp response element binding protein (creb), and dopamine and camp-regulated phosphoprotein 32 kda (darpp-32) and blunted induction of immediate early genes (iegs) c-fos, egr-1, and homer 1a in the amygdala and the nucleus accumbens (nac). |
2009-03-10 |
2023-08-12 |
mouse |
| Lars V Kristiansen, Michael J Bannon, James H Meador-Woodruf. Expression of transcripts for myelin related genes in postmortem brain from cocaine abusers. Neurochemical research. vol 34. issue 1. 2009-02-23. PMID:18357522. |
chronic abuse of cocaine is known to cause neuroadaptive changes in the nucleus accumbens (nac) and ventral tegmental area (vta). |
2009-02-23 |
2023-08-12 |
human |
| Ahmed A Othman, Amy H Newman, Natalie D Eddingto. The novel N-substituted benztropine analog GA2-50 possesses pharmacokinetic and pharmacodynamic profiles favorable for a candidate substitute medication for cocaine abuse. Journal of pharmaceutical sciences. vol 97. issue 12. 2009-02-10. PMID:18425847. |
effect of ga2-50 on the extracelluar nucleus accumbens (nac) dopamine levels and on cocaine's induced dopamine elevation was evaluated using intracerebral microdialysis. |
2009-02-10 |
2023-08-12 |
human |
| Seong-Yeol Nah, Kamal S Bhatia, Johnnie Lyles, Everett H Ellinwood, Tong H Le. Effects of ginseng saponin on acute cocaine-induced alterations in evoked dopamine release and uptake in rat brain nucleus accumbens. Brain research. vol 1248. 2009-02-03. PMID:19026615. |
we previously used the real-time fast-scan cyclic voltammetry in rat nucleus accumbens slices to demonstrate that cocaine not only enhances da release evoked by single-pulse electrical stimulation and inhibits da uptake during application but also further increases the release upon washout (termed a "rebound" release enhancement). |
2009-02-03 |
2023-08-12 |
rat |
| Rita A Fuchs, Donna R Ramirez, Guinevere H Bel. Nucleus accumbens shell and core involvement in drug context-induced reinstatement of cocaine seeking in rats. Psychopharmacology. vol 200. issue 4. 2009-01-29. PMID:18597075. |
the nucleus accumbens (nac) is a functionally heterogeneous brain region with respect to its involvement in cocaine-seeking behavior triggered by drug-associated explicit conditioned stimuli, foot shock stress, or cocaine itself in the reinstatement animal model of drug relapse. |
2009-01-29 |
2023-08-12 |
rat |
| Ryan K Bachtell, David W Sel. Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 48. 2009-01-26. PMID:19036973. |
renewed cocaine exposure produces transient alterations in nucleus accumbens ampa receptor-mediated behavior. |
2009-01-26 |
2023-08-12 |
Not clear |
| Ryan K Bachtell, David W Sel. Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 48. 2009-01-26. PMID:19036973. |
withdrawal from repeated cocaine is associated with increased synaptic and extrasynaptic ampa receptor (ampar) expression in nucleus accumbens (nac) neurons and enhanced behavioral sensitivity to ampar stimulation. |
2009-01-26 |
2023-08-12 |
Not clear |
| Wei-Lun Sun, Luyi Zhou, Ruhal Hazim, Vanya Quinones-Jenab, Shirzad Jena. Effects of dopamine and NMDA receptors on cocaine-induced Fos expression in the striatum of Fischer rats. Brain research. vol 1243. 2009-01-21. PMID:18822274. |
in this study, we show that a single cocaine administration (30 mg/kg) time-dependently increases erk phosphorylation, c-fos and fosb protein expression, and mkp-1 phosphorylation (p-mkp-1), in the caudate-putamen (cpu) and nucleus accumbens (nac) of fischer rats. |
2009-01-21 |
2023-08-12 |
rat |
| Xiao-Qing Peng, Xia Li, Jie Li, P Veeraraghavan Ramachandran, Pravin D Gagare, Debarshi Pratihar, Charles R Ashby, Eliot L Gardner, Zheng-Xiong X. Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. Drug and alcohol dependence. vol 97. issue 3. 2009-01-06. PMID:18065162. |
effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. |
2009-01-06 |
2023-08-12 |
rat |
| Xiao-Qing Peng, Xia Li, Jie Li, P Veeraraghavan Ramachandran, Pravin D Gagare, Debarshi Pratihar, Charles R Ashby, Eliot L Gardner, Zheng-Xiong X. Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. Drug and alcohol dependence. vol 97. issue 3. 2009-01-06. PMID:18065162. |
in the present study, we investigated the effects of gabapentin on intravenous cocaine self-administration and cocaine-triggered reinstatement of drug-seeking behavior, as well as on cocaine-enhanced dopamine (da) in the nucleus accumbens (nac). |
2009-01-06 |
2023-08-12 |
rat |
| Eugene A Kiyatki. Brain temperature responses to salient stimuli persist during dopamine receptor blockade despite a blockade of locomotor responses. Pharmacology, biochemistry, and behavior. vol 91. issue 2. 2009-01-06. PMID:18727935. |
we examined how an acute dopamine (da) receptor blockade affects locomotor and brain (nucleus accumbens or nacc), muscle and skin temperature responses to three arousing stimuli (procedure of sc injection, tail-pinch and social interaction with another male rat) and intravenous cocaine (1 mg/kg). |
2009-01-06 |
2023-08-12 |
rat |
| Małgorzata Frankowska, Karolina Wydra, Agata Faron-Górecka, Magdalena Zaniewska, Maciej Kuśmider, Marta Dziedzicka-Wasylewska, Małgorzata Fili. Neuroadaptive changes in the rat brain GABA(B) receptors after withdrawal from cocaine self-administration. European journal of pharmacology. vol 599. issue 1-3. 2009-01-06. PMID:18848829. |
similar decreases in the nucleus accumbens were seen in the animals passively receiving cocaine. |
2009-01-06 |
2023-08-12 |
rat |
| Shane A Perrine, Jonathon S Miller, Ellen M Unterwal. Cocaine regulates protein kinase B and glycogen synthase kinase-3 activity in selective regions of rat brain. Journal of neurochemistry. vol 107. issue 2. 2008-12-24. PMID:18717814. |
phosphorylation of akt on the threonine-308 (thr308) residue was significantly reduced in the nucleus accumbens and increased in the amygdala after 1 day of cocaine treatment; however, these effects were not accompanied by a significant decrease in gsk3 phosphorylation. |
2008-12-24 |
2023-08-12 |
rat |