| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryan K Bachtell, David W Sel. Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 48. 2009-01-26. PMID:19036973. |
renewed cocaine exposure produces transient alterations in nucleus accumbens ampa receptor-mediated behavior. |
2009-01-26 |
2023-08-12 |
Not clear |
| Ryan K Bachtell, David W Sel. Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 48. 2009-01-26. PMID:19036973. |
withdrawal from repeated cocaine is associated with increased synaptic and extrasynaptic ampa receptor (ampar) expression in nucleus accumbens (nac) neurons and enhanced behavioral sensitivity to ampar stimulation. |
2009-01-26 |
2023-08-12 |
Not clear |
| Wei-Lun Sun, Luyi Zhou, Ruhal Hazim, Vanya Quinones-Jenab, Shirzad Jena. Effects of dopamine and NMDA receptors on cocaine-induced Fos expression in the striatum of Fischer rats. Brain research. vol 1243. 2009-01-21. PMID:18822274. |
in this study, we show that a single cocaine administration (30 mg/kg) time-dependently increases erk phosphorylation, c-fos and fosb protein expression, and mkp-1 phosphorylation (p-mkp-1), in the caudate-putamen (cpu) and nucleus accumbens (nac) of fischer rats. |
2009-01-21 |
2023-08-12 |
rat |
| Xiao-Qing Peng, Xia Li, Jie Li, P Veeraraghavan Ramachandran, Pravin D Gagare, Debarshi Pratihar, Charles R Ashby, Eliot L Gardner, Zheng-Xiong X. Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. Drug and alcohol dependence. vol 97. issue 3. 2009-01-06. PMID:18065162. |
effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. |
2009-01-06 |
2023-08-12 |
rat |
| Xiao-Qing Peng, Xia Li, Jie Li, P Veeraraghavan Ramachandran, Pravin D Gagare, Debarshi Pratihar, Charles R Ashby, Eliot L Gardner, Zheng-Xiong X. Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. Drug and alcohol dependence. vol 97. issue 3. 2009-01-06. PMID:18065162. |
in the present study, we investigated the effects of gabapentin on intravenous cocaine self-administration and cocaine-triggered reinstatement of drug-seeking behavior, as well as on cocaine-enhanced dopamine (da) in the nucleus accumbens (nac). |
2009-01-06 |
2023-08-12 |
rat |
| Eugene A Kiyatki. Brain temperature responses to salient stimuli persist during dopamine receptor blockade despite a blockade of locomotor responses. Pharmacology, biochemistry, and behavior. vol 91. issue 2. 2009-01-06. PMID:18727935. |
we examined how an acute dopamine (da) receptor blockade affects locomotor and brain (nucleus accumbens or nacc), muscle and skin temperature responses to three arousing stimuli (procedure of sc injection, tail-pinch and social interaction with another male rat) and intravenous cocaine (1 mg/kg). |
2009-01-06 |
2023-08-12 |
rat |
| Małgorzata Frankowska, Karolina Wydra, Agata Faron-Górecka, Magdalena Zaniewska, Maciej Kuśmider, Marta Dziedzicka-Wasylewska, Małgorzata Fili. Neuroadaptive changes in the rat brain GABA(B) receptors after withdrawal from cocaine self-administration. European journal of pharmacology. vol 599. issue 1-3. 2009-01-06. PMID:18848829. |
similar decreases in the nucleus accumbens were seen in the animals passively receiving cocaine. |
2009-01-06 |
2023-08-12 |
rat |
| Shane A Perrine, Jonathon S Miller, Ellen M Unterwal. Cocaine regulates protein kinase B and glycogen synthase kinase-3 activity in selective regions of rat brain. Journal of neurochemistry. vol 107. issue 2. 2008-12-24. PMID:18717814. |
phosphorylation of akt on the threonine-308 (thr308) residue was significantly reduced in the nucleus accumbens and increased in the amygdala after 1 day of cocaine treatment; however, these effects were not accompanied by a significant decrease in gsk3 phosphorylation. |
2008-12-24 |
2023-08-12 |
rat |
| Shane A Perrine, Jonathon S Miller, Ellen M Unterwal. Cocaine regulates protein kinase B and glycogen synthase kinase-3 activity in selective regions of rat brain. Journal of neurochemistry. vol 107. issue 2. 2008-12-24. PMID:18717814. |
the findings in nucleus accumbens may reflect dopaminergic motor-stimulant activity caused by acute cocaine, whereas the effects in amygdala may be associated with changes in emotional state that occur after acute and chronic cocaine exposure. |
2008-12-24 |
2023-08-12 |
rat |
| K Fuxe, D Marcellino, A Rivera, Z Diaz-Cabiale, M Filip, B Gago, D C S Roberts, U Langel, S Genedani, L Ferraro, A de la Calle, J Narvaez, S Tanganelli, A Woods, L F Agnat. Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18222544. |
recently, a(2a) receptors also have been shown to counteract the locomotor and sensitizing actions of cocaine and increases in a(2a) receptors have also been observed in the nucleus accumbens after extended cocaine self-administration, probably representing a compensatory up-regulation to counteract the cocaine-induced increases in dopamine d(2) and d(3) signaling. |
2008-12-18 |
2023-08-12 |
Not clear |
| Manoranjan S D'Souza, Christine L Duvauchell. Certain or uncertain cocaine expectations influence accumbens dopamine responses to self-administered cocaine and non-rewarded operant behavior. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 9. 2008-12-18. PMID:18499407. |
the present study was conducted to determine the influence of cue-induced cocaine uncertainty, certainty and prediction error on nucleus accumbens dopamine (nacc da) in rats. |
2008-12-18 |
2023-08-12 |
human |
| R Numa, R Kohen, T Poltyrev, R Yak. Tempol diminishes cocaine-induced oxidative damage and attenuates the development and expression of behavioral sensitization. Neuroscience. vol 155. issue 3. 2008-12-18. PMID:18619523. |
acute cocaine treatment significantly elevated os markers in prefrontal cortex (pfc) and nucleus accumbens (nac) in rats, both in slices and following a single cocaine injection, which corresponded with a decrease in total antioxidant capacity (tac). |
2008-12-18 |
2023-08-12 |
rat |
| M C Hearing, R E See, J F McGint. Relapse to cocaine-seeking increases activity-regulated gene expression differentially in the striatum and cerebral cortex of rats following short or long periods of abstinence. Brain structure & function. vol 213. issue 1-2. 2008-12-02. PMID:18488248. |
re-exposure to the environment previously associated with cocaine self-administration following 22 h or 15 days of abstinence produced a significant increase in zif/268 and arc, but not c-fos mrna, in the caudate-putamen and nucleus accumbens. |
2008-12-02 |
2023-08-12 |
rat |
| Katie R Famous, Vidhya Kumaresan, Ghazaleh Sadri-Vakili, Heath D Schmidt, Dale F Mierke, Jang-Ho J Cha, R Christopher Pierc. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 43. 2008-12-01. PMID:18945913. |
phosphorylation-dependent trafficking of glur2-containing ampa receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. |
2008-12-01 |
2023-08-12 |
Not clear |
| Katie R Famous, Vidhya Kumaresan, Ghazaleh Sadri-Vakili, Heath D Schmidt, Dale F Mierke, Jang-Ho J Cha, R Christopher Pierc. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 43. 2008-12-01. PMID:18945913. |
a growing body of evidence indicates that enhanced ampa-mediated glutamate transmission in the core of the nucleus accumbens is critically involved in cocaine priming-induced reinstatement of drug seeking, an animal model of relapse. |
2008-12-01 |
2023-08-12 |
Not clear |
| Katie R Famous, Vidhya Kumaresan, Ghazaleh Sadri-Vakili, Heath D Schmidt, Dale F Mierke, Jang-Ho J Cha, R Christopher Pierc. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 43. 2008-12-01. PMID:18945913. |
in the present experiments, administration of the ampa/kainate receptor antagonist cnqx (0, 0.03, or 0.3 mug) into either the core or the shell of the nucleus accumbens before a systemic cocaine priming injection (10 mg/kg, i.p.) |
2008-12-01 |
2023-08-12 |
Not clear |
| Katie R Famous, Vidhya Kumaresan, Ghazaleh Sadri-Vakili, Heath D Schmidt, Dale F Mierke, Jang-Ho J Cha, R Christopher Pierc. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 43. 2008-12-01. PMID:18945913. |
the present results also demonstrate that the reinstatement of cocaine seeking is associated with increases in the phosphorylation-dependent trafficking of glur2-containing ampa receptors in the nucleus accumbens. |
2008-12-01 |
2023-08-12 |
Not clear |
| Esther Y Maier, Ramon T Ledesma, Andrew P Seiwell, Christine L Duvauchell. Diazepam alters cocaine self-administration, but not cocaine-stimulated locomotion or nucleus accumbens dopamine. Pharmacology, biochemistry, and behavior. vol 91. issue 1. 2008-11-06. PMID:18691612. |
diazepam alters cocaine self-administration, but not cocaine-stimulated locomotion or nucleus accumbens dopamine. |
2008-11-06 |
2023-08-12 |
rat |
| Esther Y Maier, Ramon T Ledesma, Andrew P Seiwell, Christine L Duvauchell. Diazepam alters cocaine self-administration, but not cocaine-stimulated locomotion or nucleus accumbens dopamine. Pharmacology, biochemistry, and behavior. vol 91. issue 1. 2008-11-06. PMID:18691612. |
cocaine is known to enhance nucleus accumbens dopamine (nacc da), to serve as a positive reinforcer and to produce negative effects, such as anxiety. |
2008-11-06 |
2023-08-12 |
rat |
| Paul S Frankel, Mario E Alburges, Lloyd Bush, Glen R Hanson, Stephen J Kis. Striatal and ventral pallidum dynorphin concentrations are markedly increased in human chronic cocaine users. Neuropharmacology. vol 55. issue 1. 2008-11-05. PMID:18538358. |
in this autopsied brain study, our major objective was to establish by radioimmunoassay whether levels of dynorphin and other neuropeptides (e.g., metenkephalin, neurotensin and substance p) are increased in the dopamine-rich caudate, putamen, and nucleus accumbens of human chronic cocaine users (n=12) vs. matched control subjects (n=17) as predicted by animal findings. |
2008-11-05 |
2023-08-12 |
human |