Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Brandon J Aragona, Nathan A Cleaveland, Garret D Stuber, Jeremy J Day, Regina M Carelli, R Mark Wightma. Preferential enhancement of dopamine transmission within the nucleus accumbens shell by cocaine is attributable to a direct increase in phasic dopamine release events. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 35. 2008-09-18. PMID:18753384. |
preferential enhancement of dopamine transmission within the nucleus accumbens (nac) shell is a fundamental aspect of the neural regulation of cocaine reward. |
2008-09-18 |
2023-08-12 |
Not clear |
Thomas F Tropea, Barry E Kosofsky, Anjali M Rajadhyaksh. Enhanced CREB and DARPP-32 phosphorylation in the nucleus accumbens and CREB, ERK, and GluR1 phosphorylation in the dorsal hippocampus is associated with cocaine-conditioned place preference behavior. Journal of neurochemistry. vol 106. issue 4. 2008-09-12. PMID:18554320. |
to better understand the mechanism of cocaine-conditioned place preference we have used western blot analysis to examine changes in phosphorylation of camp-response element binding protein (creb), dopamine- and cyclic amp-regulated phosphoprotein 32 (darpp-32), extracellular signal-regulated kinase (erk) and glur1, key molecular substrates altered by cocaine, in the nucleus accumbens (nac) and dorsal hippocampus (dhc) of c57bl/6 mice. |
2008-09-12 |
2023-08-12 |
mouse |
Lisa M Ambrose-Lanci, Niluk B Peiris, Ellen M Unterwald, Elisabeth J Van Bockstael. Cocaine withdrawal-induced trafficking of delta-opioid receptors in rat nucleus accumbens. Brain research. vol 1210. 2008-08-26. PMID:18417105. |
cocaine withdrawal-induced trafficking of delta-opioid receptors in rat nucleus accumbens. |
2008-08-26 |
2023-08-12 |
rat |
Lisa M Ambrose-Lanci, Niluk B Peiris, Ellen M Unterwald, Elisabeth J Van Bockstael. Cocaine withdrawal-induced trafficking of delta-opioid receptors in rat nucleus accumbens. Brain research. vol 1210. 2008-08-26. PMID:18417105. |
interactions between the opioidergic and dopaminergic systems in the nucleus accumbens (nacb) play a critical role in mediating cocaine withdrawal-induced effects on cell signaling and behavior. |
2008-08-26 |
2023-08-12 |
rat |
Ryan M Franke, Minjung Park, James D Belluzzi, Frances M Lesli. Prenatal nicotine exposure changes natural and drug-induced reinforcement in adolescent male rats. The European journal of neuroscience. vol 27. issue 11. 2008-08-20. PMID:18588535. |
nicotine-exposed adolescents did not self-administer the low dose of cocaine, but, at the higher dose, exhibited significantly greater cocaine intake and c-fos mrna expression in nucleus accumbens than did controls. |
2008-08-20 |
2023-08-12 |
rat |
Seungwoo Kim, Jeong-Hoon Ki. Time-dependent change of ERK phosphorylation levels in the nucleus accumbens during withdrawals from repeated cocaine. Neuroscience letters. vol 436. issue 2. 2008-08-13. PMID:18359158. |
time-dependent change of erk phosphorylation levels in the nucleus accumbens during withdrawals from repeated cocaine. |
2008-08-13 |
2023-08-12 |
rat |
Seungwoo Kim, Jeong-Hoon Ki. Time-dependent change of ERK phosphorylation levels in the nucleus accumbens during withdrawals from repeated cocaine. Neuroscience letters. vol 436. issue 2. 2008-08-13. PMID:18359158. |
we sought to determine whether erk activation in the nucleus accumbens (nacc), the site mediating the expression of behavioral sensitization, shows time-dependent changes after cocaine withdrawals. |
2008-08-13 |
2023-08-12 |
rat |
Panayotis K Thanos, Michael Michaelides, Hiroyuki Umegaki, Nora D Volko. D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats. Synapse (New York, N.Y.). vol 62. issue 7. 2008-08-11. PMID:18418874. |
d2r dna transfer into the nucleus accumbens attenuates cocaine self-administration in rats. |
2008-08-11 |
2023-08-12 |
human |
Thomas J Martin, Michael Coller, Conchita Co, James E Smit. Micro-opioid receptor alkylation in the ventral pallidum and ventral tegmental area, but not in the nucleus accumbens, attenuates the effects of heroin on cocaine self-administration in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 5. 2008-08-01. PMID:17581528. |
data from animal research indicate that the reinforcing efficacy of low doses of cocaine is potentiated by the addition of small amounts of heroin and that this potentiation is accompanied by synergistic increases in nucleus accumbens (nac) extracellular fluid levels of dopamine. |
2008-08-01 |
2023-08-12 |
rat |
Jennifer A Stamp, Rahia Mashoodh, Jackalina M van Kampen, Harold A Robertso. Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and DeltaFosB expression in the nucleus accumbens of the rat. Brain research. vol 1204. 2008-07-22. PMID:18342839. |
in the present study, chronic mild food restriction was used as a stressor to investigate its effect on the locomotor simulant effects of cocaine as well as fosb expression in the nucleus accumbens and caudate putamen. |
2008-07-22 |
2023-08-12 |
human |
Tod E Kippin, Karen K Szumlinski, Zuzana Kapasova, Betsy Rezner, Ronald E Se. Prenatal stress enhances responsiveness to cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 4. 2008-07-03. PMID:17487224. |
relative to controls, a noncontingent cocaine injection elevated locomotor activity as well as nucleus accumbens levels of extracellular dopamine and glutamate to a greater extent in both cocaine-naive and cocaine-experienced prenatal stress (pns) rats and elevated prefrontal cortex dopamine in cocaine-experienced pns rats. |
2008-07-03 |
2023-08-12 |
rat |
Ryan K Bachtell, Kwang-Ho Choi, Diana L Simmons, Edgardo Falcon, Lisa M Monteggia, Rachael L Neve, David W Sel. Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior. The European journal of neuroscience. vol 27. issue 9. 2008-07-01. PMID:18430032. |
role of glur1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior. |
2008-07-01 |
2023-08-12 |
Not clear |
Ryan K Bachtell, Kwang-Ho Choi, Diana L Simmons, Edgardo Falcon, Lisa M Monteggia, Rachael L Neve, David W Sel. Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior. The European journal of neuroscience. vol 27. issue 9. 2008-07-01. PMID:18430032. |
chronic cocaine use reduces glutamate levels in the nucleus accumbens (nac), and is associated with experience-dependent changes in (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) glutamate receptor membrane expression in nac neurons. |
2008-07-01 |
2023-08-12 |
Not clear |
Jesus Bertran-Gonzalez, Clémentine Bosch, Matthieu Maroteaux, Miriam Matamales, Denis Hervé, Emmanuel Valjent, Jean-Antoine Giraul. Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 22. 2008-07-01. PMID:18509028. |
acute cocaine treatment increased phosphorylation of erk and its direct or indirect nuclear targets, mitogen- and stress-activated kinase-1 (msk1) and histone h3, exclusively in d1r-expressing output neurons in the dorsal striatum and nucleus accumbens. |
2008-07-01 |
2023-08-12 |
mouse |
Sharon M Anderson, Katie R Famous, Ghazaleh Sadri-Vakili, Vidhya Kumaresan, Heath D Schmidt, Caroline E Bass, Ernest F Terwilliger, Jang-Ho J Cha, R Christopher Pierc. CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18278040. |
increases in dopamine and glutamate transmission in the nucleus accumbens independently promote the reinstatement of cocaine seeking, an animal model of relapse. |
2008-06-16 |
2023-08-12 |
rat |
Rosana Camarini, William C Griffin, Amy B Yanke, Benvinda Rosalina dos Santos, M Foster Oliv. Effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of DBA/2J mice. Brain research. vol 1193. 2008-06-03. PMID:18178178. |
effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of dba/2j mice. |
2008-06-03 |
2023-08-12 |
mouse |
Rosana Camarini, William C Griffin, Amy B Yanke, Benvinda Rosalina dos Santos, M Foster Oliv. Effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of DBA/2J mice. Brain research. vol 1193. 2008-06-03. PMID:18178178. |
to explore this further, we evaluated the locomotor responses to repeated cocaine administration in adolescent and adult male dba/2j mice and alterations in extracellular levels of dopamine (da) and glutamate (glu) in the nucleus accumbens (nac) in response to a subsequent cocaine challenge. |
2008-06-03 |
2023-08-12 |
mouse |
Stefanie Th Frank, Bertram Krumm, Rainer Spanage. Cocaine-induced dopamine overflow within the nucleus accumbens measured by in vivo microdialysis: a meta-analysis. Synapse (New York, N.Y.). vol 62. issue 4. 2008-06-03. PMID:18236471. |
a meta-analysis was conducted on data obtained from published articles which used in vivo microdialysis to assess dose-response curves of cocaine on dopamine (da) overflow within the nucleus accumbens (nac). |
2008-06-03 |
2023-08-12 |
mouse |
M Miguéns, N Del Olmo, A Higuera-Matas, I Torres, C García-Lecumberri, E Ambrosi. Glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: a time course microdialysis study. Psychopharmacology. vol 196. issue 2. 2008-05-19. PMID:17940751. |
glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: a time course microdialysis study. |
2008-05-19 |
2023-08-12 |
Not clear |
Shane A Perrine, Imran S Sheikh, Chinwe A Nwaneshiudu, Joseph A Schroeder, Ellen M Unterwal. Withdrawal from chronic administration of cocaine decreases delta opioid receptor signaling and increases anxiety- and depression-like behaviors in the rat. Neuropharmacology. vol 54. issue 2. 2008-05-12. PMID:18045627. |
results showed that the inhibition of adenylyl cyclase by delta opioid receptor agonists was attenuated in the frontal cortex, nucleus accumbens and caudate putamen 24h after cessation of cocaine administration. |
2008-05-12 |
2023-08-12 |
rat |