| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryan K Bachtell, Kwang-Ho Choi, Diana L Simmons, Edgardo Falcon, Lisa M Monteggia, Rachael L Neve, David W Sel. Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior. The European journal of neuroscience. vol 27. issue 9. 2008-07-01. PMID:18430032. |
chronic cocaine use reduces glutamate levels in the nucleus accumbens (nac), and is associated with experience-dependent changes in (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) glutamate receptor membrane expression in nac neurons. |
2008-07-01 |
2023-08-12 |
Not clear |
| Jesus Bertran-Gonzalez, Clémentine Bosch, Matthieu Maroteaux, Miriam Matamales, Denis Hervé, Emmanuel Valjent, Jean-Antoine Giraul. Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 22. 2008-07-01. PMID:18509028. |
acute cocaine treatment increased phosphorylation of erk and its direct or indirect nuclear targets, mitogen- and stress-activated kinase-1 (msk1) and histone h3, exclusively in d1r-expressing output neurons in the dorsal striatum and nucleus accumbens. |
2008-07-01 |
2023-08-12 |
mouse |
| Sharon M Anderson, Katie R Famous, Ghazaleh Sadri-Vakili, Vidhya Kumaresan, Heath D Schmidt, Caroline E Bass, Ernest F Terwilliger, Jang-Ho J Cha, R Christopher Pierc. CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18278040. |
increases in dopamine and glutamate transmission in the nucleus accumbens independently promote the reinstatement of cocaine seeking, an animal model of relapse. |
2008-06-16 |
2023-08-12 |
rat |
| Rosana Camarini, William C Griffin, Amy B Yanke, Benvinda Rosalina dos Santos, M Foster Oliv. Effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of DBA/2J mice. Brain research. vol 1193. 2008-06-03. PMID:18178178. |
effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of dba/2j mice. |
2008-06-03 |
2023-08-12 |
mouse |
| Rosana Camarini, William C Griffin, Amy B Yanke, Benvinda Rosalina dos Santos, M Foster Oliv. Effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of DBA/2J mice. Brain research. vol 1193. 2008-06-03. PMID:18178178. |
to explore this further, we evaluated the locomotor responses to repeated cocaine administration in adolescent and adult male dba/2j mice and alterations in extracellular levels of dopamine (da) and glutamate (glu) in the nucleus accumbens (nac) in response to a subsequent cocaine challenge. |
2008-06-03 |
2023-08-12 |
mouse |
| Stefanie Th Frank, Bertram Krumm, Rainer Spanage. Cocaine-induced dopamine overflow within the nucleus accumbens measured by in vivo microdialysis: a meta-analysis. Synapse (New York, N.Y.). vol 62. issue 4. 2008-06-03. PMID:18236471. |
a meta-analysis was conducted on data obtained from published articles which used in vivo microdialysis to assess dose-response curves of cocaine on dopamine (da) overflow within the nucleus accumbens (nac). |
2008-06-03 |
2023-08-12 |
mouse |
| M Miguéns, N Del Olmo, A Higuera-Matas, I Torres, C García-Lecumberri, E Ambrosi. Glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: a time course microdialysis study. Psychopharmacology. vol 196. issue 2. 2008-05-19. PMID:17940751. |
glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: a time course microdialysis study. |
2008-05-19 |
2023-08-12 |
Not clear |
| Shane A Perrine, Imran S Sheikh, Chinwe A Nwaneshiudu, Joseph A Schroeder, Ellen M Unterwal. Withdrawal from chronic administration of cocaine decreases delta opioid receptor signaling and increases anxiety- and depression-like behaviors in the rat. Neuropharmacology. vol 54. issue 2. 2008-05-12. PMID:18045627. |
results showed that the inhibition of adenylyl cyclase by delta opioid receptor agonists was attenuated in the frontal cortex, nucleus accumbens and caudate putamen 24h after cessation of cocaine administration. |
2008-05-12 |
2023-08-12 |
rat |
| Joshua L Jone. Cocaine experience guides dynamic changes in AMPA receptors within the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 12. 2008-04-25. PMID:18354000. |
cocaine experience guides dynamic changes in ampa receptors within the nucleus accumbens. |
2008-04-25 |
2023-08-12 |
Not clear |
| Devadoss J Samuvel, Lankupalle D Jayanthi, Senthilvelan Manohar, Kolanjiappan Kaliyaperumal, Ronald E See, Sammanda Ramamoorth. Dysregulation of dopamine transporter trafficking and function after abstinence from cocaine self-administration in rats: evidence for differential regulation in caudate putamen and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 325. issue 1. 2008-04-22. PMID:18198344. |
dysregulation of dopamine transporter trafficking and function after abstinence from cocaine self-administration in rats: evidence for differential regulation in caudate putamen and nucleus accumbens. |
2008-04-22 |
2023-08-12 |
rat |
| BomBi Lee, Chae Ha Yang, Dae-Hyun Hahm, Hye-Jung Lee, Seung-Moo Han, Kyung-Soo Kim, Insop Shi. Inhibitory effects of ginseng total saponins on behavioral sensitization and dopamine release induced by cocaine. Biological & pharmaceutical bulletin. vol 31. issue 3. 2008-04-21. PMID:18310906. |
it has been shown that repeated injections of cocaine produce an increase in locomotor activity, the expression of the immediate-early gene, c-fos, and the release of dopamine (da) in the nucleus accumbens (nac), which is one of the main dopaminergic terminal areas. |
2008-04-21 |
2023-08-12 |
rat |
| Joshua L Jones, Robert A Wheeler, Regina M Carell. Behavioral responding and nucleus accumbens cell firing are unaltered following periods of abstinence from sucrose. Synapse (New York, N.Y.). vol 62. issue 3. 2008-04-11. PMID:18088061. |
here, we examined whether abstinence from sucrose self-administration in rats altered behavioral responding and nucleus accumbens (nac) cell firing in a manner similar to that observed following cocaine abstinence. |
2008-04-11 |
2023-08-12 |
rat |
| Alexis W Ary, Karen Kathleen Szumlinsk. Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: a two-species comparison. Brain research. vol 1184. 2008-04-08. PMID:17950706. |
in both species, withdrawal from repeated cocaine administration down-regulated homer1b/c and homer2a/b within the shell, but not the core, of the nucleus accumbens (nac), and the reduced homer levels were accompanied by decreases in mglur1a, nr2a and nr2b. |
2008-04-08 |
2023-08-12 |
mouse |
| Susan M Ferguson, Ellen S Mitchell, John F Neumaie. Increased expression of 5-HT6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine. Biological psychiatry. vol 63. issue 2. 2008-02-27. PMID:17631868. |
increased expression of 5-ht6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine. |
2008-02-27 |
2023-08-12 |
Not clear |
| Susan M Ferguson, Ellen S Mitchell, John F Neumaie. Increased expression of 5-HT6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine. Biological psychiatry. vol 63. issue 2. 2008-02-27. PMID:17631868. |
although serotonin-6 receptors (5-ht6rs) are abundantly expressed in the brain regions thought to underlie these phenomena, such as the nucleus accumbens (nac), surprisingly little is known about the role of 5-ht6rs in the rewarding and psychomotor activating effects of cocaine. |
2008-02-27 |
2023-08-12 |
Not clear |
| Frederic Boyer, Jean-Luc Dreye. Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats. The European journal of neuroscience. vol 26. issue 10. 2008-02-25. PMID:18001274. |
alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats. |
2008-02-25 |
2023-08-12 |
rat |
| Sylvia Navailles, Delphine Moison, Kathryn A Cunningham, Umberto Spampinat. Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17429406. |
differential regulation of the mesoaccumbens dopamine circuit by serotonin2c receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. |
2008-02-06 |
2023-08-12 |
rat |
| Sylvia Navailles, Delphine Moison, Kathryn A Cunningham, Umberto Spampinat. Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17429406. |
stimulation of central serotonin2c receptor (5-ht(2c)r) inhibits dopamine (da)-dependent neurochemical and behavioral effects of cocaine, while 5-ht(2c)rs locally expressed into the ventral tegmental area (vta) and the nucleus accumbens (nac) exert opposite functional control over cocaine-induced behavioral effects. |
2008-02-06 |
2023-08-12 |
rat |
| Guo-Chi Zhang, Jason Hoffmann, Nikhil K Parelkar, Xian-Yu Liu, Li-Min Mao, Eugene E Fibuch, John Q Wan. Cocaine increases Ras-guanine nucleotide-releasing factor 1 protein expression in the rat striatum in vivo. Neuroscience letters. vol 427. issue 2. 2008-01-23. PMID:17931779. |
a single systemic injection of cocaine induced an increase in ras-grf1 protein levels in both the dorsal (caudoputamen) and ventral (nucleus accumbens) striatum. |
2008-01-23 |
2023-08-12 |
rat |
| Aric Madayag, Doug Lobner, Kristen S Kau, John R Mantsch, Omer Abdulhameed, Matthew Hearing, Mark D Grier, David A Bake. Repeated N-acetylcysteine administration alters plasticity-dependent effects of cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 51. 2008-01-14. PMID:18094234. |
cocaine produces a persistent reduction in cystine-glutamate exchange via system x(c)- in the nucleus accumbens that may contribute to pathological glutamate signaling linked to addiction. |
2008-01-14 |
2023-08-12 |
Not clear |