| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A España, D C S Roberts, S R Jone. Short-acting cocaine and long-acting GBR-12909 both elicit rapid dopamine uptake inhibition following intravenous delivery. Neuroscience. vol 155. issue 1. 2008-11-05. PMID:18597947. |
cocaine (0.75, 1.5, and 3.0 mg/kg) significantly inhibited da uptake in the nucleus accumbens of anesthetized rats within 5 s. da uptake inhibition peaked at 30 s and returned to baseline levels in approximately 1 h. the effects of cocaine were dose-dependent, with the 3.0 mg/kg dose producing greater uptake inhibition at the early time points and exhibiting a longer latency to return to baseline. |
2008-11-05 |
2023-08-12 |
rat |
| Maria A de Souza Silva, Gerhard Jocham, Marilia Barros, Carlos Tomaz, Christian P Mülle. Neurokinin3 receptor modulation of the behavioral and neurochemical effects of cocaine in rats and monkeys. Reviews in the neurosciences. vol 19. issue 2-3. 2008-11-05. PMID:18751518. |
nk3 receptor agonism as well as antagonism potentiate cocaine's effects on nucleus accumbens da subregions specifically, and modulate the acute behavioral effects of cocaine in rats and non-human primates (callithrix penicillata). |
2008-11-05 |
2023-08-12 |
rat |
| Michael S Smirnov, Eugene A Kiyatki. Behavioral and temperature effects of delta 9-tetrahydrocannabinol in human-relevant doses in rats. Brain research. vol 1228. 2008-11-03. PMID:18619424. |
to study this phenomenon, we assessed how delta-9-tetrahydrocannabinol (thc), a primary psychoactive ingredient of marijuana, affects locomotor and brain (nucleus accumbens or nacc), muscle and skin temperature responses to natural arousing stimuli (one-minute tail-pinch and one-minute social interaction with another male rat) and iv cocaine (1 mg/kg) in male rats. |
2008-11-03 |
2023-08-12 |
rat |
| Suprabha Pulipparacharuvil, William Renthal, Carly F Hale, Makoto Taniguchi, Guanghua Xiao, Arvind Kumar, Scott J Russo, Devanjan Sikder, Colleen M Dewey, Maya M Davis, Paul Greengard, Angus C Nairn, Eric J Nestler, Christopher W Cowa. Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron. vol 59. issue 4. 2008-09-29. PMID:18760698. |
repeated exposure to cocaine causes sensitized behavioral responses and increased dendritic spines on medium spiny neurons of the nucleus accumbens (nac). |
2008-09-29 |
2023-08-12 |
Not clear |
| Jason N Jaworski, Stephen T Hansen, Michael J Kuhar, Gregory P Mar. Injection of CART (cocaine- and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self-administration in rats. Behavioural brain research. vol 191. issue 2. 2008-09-24. PMID:18485497. |
injection of cart (cocaine- and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self-administration in rats. |
2008-09-24 |
2023-08-12 |
rat |
| Jason N Jaworski, Stephen T Hansen, Michael J Kuhar, Gregory P Mar. Injection of CART (cocaine- and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self-administration in rats. Behavioural brain research. vol 191. issue 2. 2008-09-24. PMID:18485497. |
injections of cart peptide into the nucleus accumbens (nacc) inhibit locomotion produced by systemic injections of the psychostimulants cocaine and amphetamine. |
2008-09-24 |
2023-08-12 |
rat |
| G W Hubert, M J Kuha. Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos. Neuropeptides. vol 42. issue 3. 2008-09-19. PMID:18314190. |
cocaine administration increases the fraction of cart cells in the rat nucleus accumbens that co-immunostain for c-fos. |
2008-09-19 |
2023-08-12 |
rat |
| Xiaowei Guan, Jue Hu, Shengnan L. Involvement of extracellular signal-regulated protein kinase in acute cocaine-induced c-fos in nucleus accumbens. Neuroscience letters. vol 438. issue 2. 2008-09-19. PMID:18479823. |
in the present study, we investigated a possible involvement of extracellular signal-regulated protein kinase (erk) in induction of c-fos expression in response to acute cocaine treatment in nucleus accumbens (nac). |
2008-09-19 |
2023-08-12 |
Not clear |
| Brandon J Aragona, Nathan A Cleaveland, Garret D Stuber, Jeremy J Day, Regina M Carelli, R Mark Wightma. Preferential enhancement of dopamine transmission within the nucleus accumbens shell by cocaine is attributable to a direct increase in phasic dopamine release events. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 35. 2008-09-18. PMID:18753384. |
preferential enhancement of dopamine transmission within the nucleus accumbens (nac) shell is a fundamental aspect of the neural regulation of cocaine reward. |
2008-09-18 |
2023-08-12 |
Not clear |
| Thomas F Tropea, Barry E Kosofsky, Anjali M Rajadhyaksh. Enhanced CREB and DARPP-32 phosphorylation in the nucleus accumbens and CREB, ERK, and GluR1 phosphorylation in the dorsal hippocampus is associated with cocaine-conditioned place preference behavior. Journal of neurochemistry. vol 106. issue 4. 2008-09-12. PMID:18554320. |
to better understand the mechanism of cocaine-conditioned place preference we have used western blot analysis to examine changes in phosphorylation of camp-response element binding protein (creb), dopamine- and cyclic amp-regulated phosphoprotein 32 (darpp-32), extracellular signal-regulated kinase (erk) and glur1, key molecular substrates altered by cocaine, in the nucleus accumbens (nac) and dorsal hippocampus (dhc) of c57bl/6 mice. |
2008-09-12 |
2023-08-12 |
mouse |
| Lisa M Ambrose-Lanci, Niluk B Peiris, Ellen M Unterwald, Elisabeth J Van Bockstael. Cocaine withdrawal-induced trafficking of delta-opioid receptors in rat nucleus accumbens. Brain research. vol 1210. 2008-08-26. PMID:18417105. |
cocaine withdrawal-induced trafficking of delta-opioid receptors in rat nucleus accumbens. |
2008-08-26 |
2023-08-12 |
rat |
| Lisa M Ambrose-Lanci, Niluk B Peiris, Ellen M Unterwald, Elisabeth J Van Bockstael. Cocaine withdrawal-induced trafficking of delta-opioid receptors in rat nucleus accumbens. Brain research. vol 1210. 2008-08-26. PMID:18417105. |
interactions between the opioidergic and dopaminergic systems in the nucleus accumbens (nacb) play a critical role in mediating cocaine withdrawal-induced effects on cell signaling and behavior. |
2008-08-26 |
2023-08-12 |
rat |
| Ryan M Franke, Minjung Park, James D Belluzzi, Frances M Lesli. Prenatal nicotine exposure changes natural and drug-induced reinforcement in adolescent male rats. The European journal of neuroscience. vol 27. issue 11. 2008-08-20. PMID:18588535. |
nicotine-exposed adolescents did not self-administer the low dose of cocaine, but, at the higher dose, exhibited significantly greater cocaine intake and c-fos mrna expression in nucleus accumbens than did controls. |
2008-08-20 |
2023-08-12 |
rat |
| Seungwoo Kim, Jeong-Hoon Ki. Time-dependent change of ERK phosphorylation levels in the nucleus accumbens during withdrawals from repeated cocaine. Neuroscience letters. vol 436. issue 2. 2008-08-13. PMID:18359158. |
time-dependent change of erk phosphorylation levels in the nucleus accumbens during withdrawals from repeated cocaine. |
2008-08-13 |
2023-08-12 |
rat |
| Seungwoo Kim, Jeong-Hoon Ki. Time-dependent change of ERK phosphorylation levels in the nucleus accumbens during withdrawals from repeated cocaine. Neuroscience letters. vol 436. issue 2. 2008-08-13. PMID:18359158. |
we sought to determine whether erk activation in the nucleus accumbens (nacc), the site mediating the expression of behavioral sensitization, shows time-dependent changes after cocaine withdrawals. |
2008-08-13 |
2023-08-12 |
rat |
| Panayotis K Thanos, Michael Michaelides, Hiroyuki Umegaki, Nora D Volko. D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats. Synapse (New York, N.Y.). vol 62. issue 7. 2008-08-11. PMID:18418874. |
d2r dna transfer into the nucleus accumbens attenuates cocaine self-administration in rats. |
2008-08-11 |
2023-08-12 |
human |
| Thomas J Martin, Michael Coller, Conchita Co, James E Smit. Micro-opioid receptor alkylation in the ventral pallidum and ventral tegmental area, but not in the nucleus accumbens, attenuates the effects of heroin on cocaine self-administration in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 5. 2008-08-01. PMID:17581528. |
data from animal research indicate that the reinforcing efficacy of low doses of cocaine is potentiated by the addition of small amounts of heroin and that this potentiation is accompanied by synergistic increases in nucleus accumbens (nac) extracellular fluid levels of dopamine. |
2008-08-01 |
2023-08-12 |
rat |
| Jennifer A Stamp, Rahia Mashoodh, Jackalina M van Kampen, Harold A Robertso. Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and DeltaFosB expression in the nucleus accumbens of the rat. Brain research. vol 1204. 2008-07-22. PMID:18342839. |
in the present study, chronic mild food restriction was used as a stressor to investigate its effect on the locomotor simulant effects of cocaine as well as fosb expression in the nucleus accumbens and caudate putamen. |
2008-07-22 |
2023-08-12 |
human |
| Tod E Kippin, Karen K Szumlinski, Zuzana Kapasova, Betsy Rezner, Ronald E Se. Prenatal stress enhances responsiveness to cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 4. 2008-07-03. PMID:17487224. |
relative to controls, a noncontingent cocaine injection elevated locomotor activity as well as nucleus accumbens levels of extracellular dopamine and glutamate to a greater extent in both cocaine-naive and cocaine-experienced prenatal stress (pns) rats and elevated prefrontal cortex dopamine in cocaine-experienced pns rats. |
2008-07-03 |
2023-08-12 |
rat |
| Ryan K Bachtell, Kwang-Ho Choi, Diana L Simmons, Edgardo Falcon, Lisa M Monteggia, Rachael L Neve, David W Sel. Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior. The European journal of neuroscience. vol 27. issue 9. 2008-07-01. PMID:18430032. |
role of glur1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior. |
2008-07-01 |
2023-08-12 |
Not clear |