Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Vitaly Palamarchouk, Gennady Smagin, Nicholas E Goeder. Self-administered and passive cocaine infusions produce different effects on corticosterone concentrations in the medial prefrontal cortex (MPC) of rats. Pharmacology, biochemistry, and behavior. vol 94. issue 1. 2009-12-17. PMID:19698740. |
in these experiments, we measured corticosterone in microdialysis samples collected from probes aimed at the medial prefrontal cortex, nucleus accumbens and basolateral amygdala in rats self-administering cocaine and receiving identical, passive infusions of cocaine or saline. |
2009-12-17 |
2023-08-12 |
rat |
W Y Kim, S R Shin, S Kim, S Jeon, J-H Ki. Cocaine regulates ezrin-radixin-moesin proteins and RhoA signaling in the nucleus accumbens. Neuroscience. vol 163. issue 2. 2009-12-14. PMID:19580848. |
cocaine regulates ezrin-radixin-moesin proteins and rhoa signaling in the nucleus accumbens. |
2009-12-14 |
2023-08-12 |
rat |
Jérémie Lavaur, Yann S Mineur, Marina R Picciott. The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780900. |
the membrane cytoskeletal protein adducin is phosphorylated by protein kinase c in d1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. |
2009-12-11 |
2023-08-12 |
Not clear |
Jérémie Lavaur, Yann S Mineur, Marina R Picciott. The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780900. |
cocaine administration increases levels of f-actin in the nucleus accumbens and is associated with changes in the phosphorylation state of actin-binding proteins. |
2009-12-11 |
2023-08-12 |
Not clear |
Jérémie Lavaur, Yann S Mineur, Marina R Picciott. The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780900. |
in the current study, we characterized the regulation of adducin phosphorylation in the nucleus accumbens and dorsal striatum in response to various regimen of cocaine. |
2009-12-11 |
2023-08-12 |
Not clear |
Su-Mi Park, Ron P A Gaykema, Lisa E Goehle. How does immune challenge inhibit ingestion of palatable food? Evidence that systemic lipopolysaccharide treatment modulates key nodal points of feeding neurocircuitry. Brain, behavior, and immunity. vol 22. issue 8. 2009-11-17. PMID:18562160. |
sweetened milk ingestion was associated with increased numbers of c-fos positive neurons in the caudal core and shell of the nucleus accumbens (nac), the paraventricular thalamus (pvt), central nucleus of the amygdala (cea), the basal lateral amygdala (bla), in orexin-a containing neurons of the lateral hypothalamus (lh), and in cocaine and amphetamine regulated transcript (cart) neurons of the arcuate hypothalamus. |
2009-11-17 |
2023-08-12 |
Not clear |
Ilana Roth-Deri, Alexander Friedman, Lital Abraham, Elad Lax, Yakov Flaumenhaft, Yahav Dikshtein, Gal Yadi. Antidepressant treatment facilitates dopamine release and drug seeking behavior in a genetic animal model of depression. The European journal of neuroscience. vol 30. issue 3. 2009-10-27. PMID:19614746. |
fsl rats exhibited low but dose-dependent increases in extracellular levels of dopamine in the nucleus accumbens after acute intravenous cocaine injection. |
2009-10-27 |
2023-08-12 |
rat |
Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
regulation of dynamin 2 and g protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. |
2009-10-26 |
2023-08-12 |
rat |
Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
acute binge-pattern cocaine administration produced a significant increase in both dynamin 2- and grk2-immunoreactivity (227% and 358% of control) in the nucleus accumbens and gkr2 (150% of control) in the caudate putamen. |
2009-10-26 |
2023-08-12 |
rat |
Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
in contrast, dynamin 2 and grk2 were significantly decreased in the nucleus accumbens after chronic cocaine. |
2009-10-26 |
2023-08-12 |
rat |
Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
pretreatment with either the dopamine (da) d1 receptor antagonist sch 23390 or d2 receptor antagonist eticlopride prior to acute cocaine blocked the upregulation of dynamin 2 and grk2 in the nucleus accumbens. |
2009-10-26 |
2023-08-12 |
rat |
Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
these results demonstrate that two proteins involved in receptor and transporter trafficking are selectively regulated in the nucleus accumbens following acute versus chronic cocaine exposure, and dopamine receptor activation is required for this regulation. |
2009-10-26 |
2023-08-12 |
rat |
Carmen del Castillo, Lidia Morales, Luis F Alguacil, Elisabet Salas, Elisa Garrido, Elba Alonso, Carmen Pérez-Garcí. Proteomic analysis of the nucleus accumbens of rats with different vulnerability to cocaine addiction. Neuropharmacology. vol 57. issue 1. 2009-10-01. PMID:19393250. |
proteomic analysis of the nucleus accumbens of rats with different vulnerability to cocaine addiction. |
2009-10-01 |
2023-08-12 |
rat |
Carmen del Castillo, Lidia Morales, Luis F Alguacil, Elisabet Salas, Elisa Garrido, Elba Alonso, Carmen Pérez-Garcí. Proteomic analysis of the nucleus accumbens of rats with different vulnerability to cocaine addiction. Neuropharmacology. vol 57. issue 1. 2009-10-01. PMID:19393250. |
once the phenotype was established, we compared the protein expression in the nucleus accumbens (nac) of these animals after a single injection of either saline (sal) or cocaine (coc, 15 mg/kg). |
2009-10-01 |
2023-08-12 |
rat |
John E Kelsey, Ellen J Willmor. Electrolytic lesions of the nucleus accumbens enhance locomotor sensitization to nicotine in rats. Behavioral neuroscience. vol 120. issue 3. 2009-09-30. PMID:16768612. |
electrolytic lesions of the medial core of the nucleus accumbens (nac) in male long-evans rats increased spontaneous locomotion, enhanced the locomotor stimulating effect of acute 5.0 mg/kg cocaine, enhanced the development and subsequent expression of locomotor sensitization produced by repeated injections of 0.4 mg/kg nicotine but not 7.5 mg/kg cocaine, and enhanced the expression of conditioned locomotion. |
2009-09-30 |
2023-08-12 |
rat |
Gianluigi Tanda, Amy Hauck Newman, Aaron L Ebbs, Valeria Tronci, Jennifer L Green, Ronald J Tallarida, Jonathan L Kat. Combinations of cocaine with other dopamine uptake inhibitors: assessment of additivity. The Journal of pharmacology and experimental therapeutics. vol 330. issue 3. 2009-09-21. PMID:19483071. |
effects of combinations of cocaine with a cocaine analog, 2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane (win 35,428), were compared quantitatively with the combinations of cocaine with the n-butyl,4',4''-dif benztropine analog, 3-(bis(4-fluorophenyl)methoxy)-8-butyl-8-azabicyclo[3.2.1]octane (jhw 007), to determine whether their effects on da levels in the shell of the nucleus accumbens (nac) in mice differed. |
2009-09-21 |
2023-08-12 |
mouse |
Catharine A Winstanley, Thomas A Green, David E H Theobald, William Renthal, Quincey LaPlant, Ralph J DiLeone, Sumana Chakravarty, Eric J Nestle. DeltaFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine. Pharmacology, biochemistry, and behavior. vol 93. issue 3. 2009-09-16. PMID:19135469. |
analysis of nucleus accumbens tissue taken from rats over-expressing deltafosb in the ofc and treated chronically with saline or cocaine does not provide support for the hypothesis that increasing ofc deltafosb potentiates sensitization via the nucleus accumbens. |
2009-09-16 |
2023-08-12 |
rat |
Manuel Mameli, Briac Halbout, Cyril Creton, David Engblom, Jan Rodriguez Parkitna, Rainer Spanagel, Christian Lüsche. Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc. Nature neuroscience. vol 12. issue 8. 2009-09-09. PMID:19597494. |
in the ventral tegmental area (vta), a single exposure to cocaine efficiently triggers nmda receptor-dependent synaptic plasticity in da neurons, whereas plasticity in the nucleus accumbens (nac) occurs only after repeated injections. |
2009-09-09 |
2023-08-12 |
mouse |
Darlene H Brunzell, Yann S Mineur, Rachael L Neve, Marina R Picciott. Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 8. 2009-09-02. PMID:19212318. |
previous studies have implicated nucleus accumbens (nac) creb activity in the modulation of cocaine and morphine reward, and have shown that nicotine conditioned place preference (cpp) is associated with nac creb activation. |
2009-09-02 |
2023-08-12 |
mouse |
Guo-Chi Zhang, Li-Min Mao, John Q Wang, Xiang-Ping Ch. Upregulation of acid-sensing ion channel 1 protein expression by chronic administration of cocaine in the mouse striatum in vivo. Neuroscience letters. vol 459. issue 3. 2009-08-24. PMID:19427358. |
we found that chronic systemic injection of cocaine (20mg/kg, once daily for 5 consecutive days; 14 days of withdrawal) increased asic1, but not asic2, protein levels in the striatum, including the dorsal (caudate putamen) and the ventral (nucleus accumbens) striatum. |
2009-08-24 |
2023-08-12 |
mouse |