| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Annelyn Torres-Reveron, Jeremy Weedon, Diana L Dow-Edward. Methylphenidate response in prenatal cocaine-exposed rats: a behavioral and brain functional study. Brain research. vol 1337. 2010-08-25. PMID:20382132. |
prenatal cocaine produced insignificant effects on the rates of brain glucose metabolism overall but produced a reduced response to mpd in the nucleus accumbens in a rostral/caudal gradient compared to control. |
2010-08-25 |
2023-08-12 |
rat |
| Lori A Knackstedt, Khaled Moussawi, Ryan Lalumiere, Marek Schwendt, Matthias Klugmann, Peter W Kaliva. Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 23. 2010-08-24. PMID:20534846. |
rats were either extinguished or withdrawn without extinction training (abstinence) from cocaine self-administration, and measurements of postsynaptic density proteins in the core and shell subcompartments of the nucleus accumbens were compared with yoked-saline controls. |
2010-08-24 |
2023-08-12 |
rat |
| Mary M Torregrossa, Hayde Sanchez, Jane R Taylo. D-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 31. 2010-08-24. PMID:20685995. |
d-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens. |
2010-08-24 |
2023-08-12 |
human |
| Michel M M Verheij, Eric L W de Mulder, Elvira De Leonibus, Karen M J van Loo, Alexander R Cool. Rats that differentially respond to cocaine differ in their dopaminergic storage capacity of the nucleus accumbens. Journal of neurochemistry. vol 105. issue 6. 2010-08-13. PMID:18315567. |
rats that differentially respond to cocaine differ in their dopaminergic storage capacity of the nucleus accumbens. |
2010-08-13 |
2023-08-12 |
rat |
| Angelica Rocha, Peter W Kaliva. Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seeking. The European journal of neuroscience. vol 31. issue 5. 2010-07-12. PMID:20180839. |
although the involvement of the medial prefrontal cortex projection to the nucleus accumbens in the reinstatement of cocaine seeking has been well studied, it is not known if this projection plays a similar role in the reinstatement of cue- and methamphetamine-induced drug seeking in animals extinguished from methamphetamine self-administration. |
2010-07-12 |
2023-08-12 |
rat |
| Fernando Kasanetz, Véronique Deroche-Gamonet, Nadège Berson, Eric Balado, Mathieu Lafourcade, Olivier Manzoni, Pier Vincenzo Piazz. Transition to addiction is associated with a persistent impairment in synaptic plasticity. Science (New York, N.Y.). vol 328. issue 5986. 2010-07-08. PMID:20576893. |
cocaine self-administration rapidly suppresses long-term depression (ltd), an important form of synaptic plasticity in the nucleus accumbens. |
2010-07-08 |
2023-08-12 |
rat |
| Jacqueline F McGinty, Timothy W Whitfield, William J Berglin. Brain-derived neurotrophic factor and cocaine addiction. Brain research. vol 1314. 2010-06-07. PMID:19732758. |
conversely, repeated administration of bdnf antiserum into the nucleus accumbens during chronic cocaine self-administration attenuates cocaine-induced reinstatement. |
2010-06-07 |
2023-08-12 |
Not clear |
| Jacqueline F McGinty, Timothy W Whitfield, William J Berglin. Brain-derived neurotrophic factor and cocaine addiction. Brain research. vol 1314. 2010-06-07. PMID:19732758. |
furthermore, 3 weeks after bdnf infusion in animals with a cocaine self-administration history, suppressed basal levels of glutamate are normalized and a cocaine prime-induced increase in extracellular glutamate levels in the nucleus accumbens is prevented. |
2010-06-07 |
2023-08-12 |
Not clear |
| Analía Valdomero, Cristian Hansen, Nelia Gerez de Burgos, Gabriel R Cuadra, Otto A Orsinghe. GM1 ganglioside enhances the rewarding properties of cocaine in rats. European journal of pharmacology. vol 630. issue 1-3. 2010-05-24. PMID:20044989. |
in addition, gm1 (100microm) did not alter the dopamine transporter inhibition induced by cocaine (10(-7)-10(-5)m), as determined by the uptake of [(3-)h]-dopamine in the microsacs of nucleus accumbens. |
2010-05-24 |
2023-08-12 |
rat |
| Daniel Marcellino, Gemma Navarro, Kristoffer Sahlholm, Johanna Nilsson, Luigi F Agnati, Enric I Canela, Carme Lluís, Peter Århem, Rafael Franco, Kjell Fux. Cocaine produces D2R-mediated conformational changes in the adenosine A(2A)R-dopamine D2R heteromer. Biochemical and biophysical research communications. vol 394. issue 4. 2010-05-13. PMID:20307491. |
recent findings give neurochemical evidence that extended cocaine self-administration in the rat give rise to an up-regulation of functional a(2a)rs in the nucleus accumbens that return to baseline expression levels during cocaine withdrawal. |
2010-05-13 |
2023-08-12 |
human |
| Qiang Chen, Xiongzhao Zhu, Yu Zhang, William C Wetsel, Tong H Lee, Xiuwu Zhan. Integrin-linked kinase is involved in cocaine sensitization by regulating PSD-95 and synapsin I expression and GluR1 Ser845 phosphorylation. Journal of molecular neuroscience : MN. vol 40. issue 3. 2010-05-07. PMID:19629758. |
our recent studies have demonstrated that integrin-linked kinase (ilk) is involved in the induction and maintenance of cocaine behavioral sensitization and chronic cocaine-induced neural plasticity in the nucleus accumbens (nac) core. |
2010-05-07 |
2023-08-12 |
rat |
| Willard M Freeman, Melinda E Lull, Kruti M Patel, Robert M Brucklacher, Drake Morgan, David C S Roberts, Kent E Vran. Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration. BMC neuroscience. vol 11. 2010-05-06. PMID:20187946. |
gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration. |
2010-05-06 |
2023-08-12 |
Not clear |
| Lionel Host, Patrick Anglard, Pascal Romieu, Christelle Thibault, Doulaye Dembele, Dominique Aunis, Jean Zwille. Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique. Journal of neurochemistry. vol 113. issue 1. 2010-04-30. PMID:20132486. |
in the present study, we investigated alterations in gene expression patterns in the anterior cingulate cortex and nucleus accumbens of rats self-administering cocaine and treated with tsa. |
2010-04-30 |
2023-08-12 |
rat |
| Lionel Host, Patrick Anglard, Pascal Romieu, Christelle Thibault, Doulaye Dembele, Dominique Aunis, Jean Zwille. Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique. Journal of neurochemistry. vol 113. issue 1. 2010-04-30. PMID:20132486. |
using oligonucleotide microarrays, we identified 722 probe sets in the cortex and 136 probe sets in the nucleus accumbens that were differentially expressed between vehicle and tsa-treated rats that self-administered cocaine. |
2010-04-30 |
2023-08-12 |
rat |
| Lionel Host, Patrick Anglard, Pascal Romieu, Christelle Thibault, Doulaye Dembele, Dominique Aunis, Jean Zwille. Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique. Journal of neurochemistry. vol 113. issue 1. 2010-04-30. PMID:20132486. |
tsa treatment was found to up-regulate both lis1 and reelin protein expression in the cortex and to down-regulate it in the nucleus accumbens of rats self-administering cocaine. |
2010-04-30 |
2023-08-12 |
rat |
| Ping Mu, Jason T Moyer, Masago Ishikawa, Yonghong Zhang, Jaak Panksepp, Barbara A Sorg, Oliver M Schlüter, Yan Don. Exposure to cocaine dynamically regulates the intrinsic membrane excitability of nucleus accumbens neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 10. 2010-04-09. PMID:20220002. |
exposure to cocaine dynamically regulates the intrinsic membrane excitability of nucleus accumbens neurons. |
2010-04-09 |
2023-08-12 |
rat |
| Xiao-Qing Peng, Jie Li, Eliot L Gardner, Charles R Ashby, Ajit Thomas, Krystyna Wozniak, Barbara S Slusher, Zheng-Xiong X. Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats. European journal of pharmacology. vol 627. issue 1-3. 2010-04-05. PMID:19887067. |
we have recently reported that the endogenous mglu2/3 agonist n-acetylaspartylglutamate (naag) and the n-acetylated-alpha-linked-acidic dipeptidase (naaladase, a naag degradation enzyme) inhibitor 2-pmpa significantly inhibit cocaine self-administration and cocaine-induced reinstatement of drug-seeking behavior by attenuating cocaine-enhanced extracellular dopamine and glutamate in the nucleus accumbens. |
2010-04-05 |
2023-08-12 |
rat |
| Heath D Schmidt, R Christopher Pierc. Cocaine-induced neuroadaptations in glutamate transmission: potential therapeutic targets for craving and addiction. Annals of the New York Academy of Sciences. vol 1187. 2010-04-02. PMID:20201846. |
a growing body of evidence indicates that repeated exposure to cocaine leads to profound changes in glutamate transmission in limbic nuclei, particularly the nucleus accumbens. |
2010-04-02 |
2023-08-12 |
Not clear |
| N S Tannu, L L Howell, S E Hemb. Integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration. Molecular psychiatry. vol 15. issue 2. 2010-03-30. PMID:18504425. |
integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration. |
2010-03-30 |
2023-08-12 |
human |
| N S Tannu, L L Howell, S E Hemb. Integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration. Molecular psychiatry. vol 15. issue 2. 2010-03-30. PMID:18504425. |
the reinforcing effects and long-term consequences of cocaine self-administration have been associated with brain regions of the mesolimbic dopamine pathway, namely the nucleus accumbens (nac). |
2010-03-30 |
2023-08-12 |
human |