| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cassia N Cearley, Kelly Blindheim, Barbara A Sorg, James M Krueger, Lynn Churchil. Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochemical research. vol 36. issue 4. 2011-08-02. PMID:21399909. |
il1β mrna levels after an acute exposure to cocaine (5 mg/kg, ip) at dark onset were significantly higher than those obtained from rats sacrificed after an acute exposure to saline in the piriform and somatosensory cortex, and nucleus accumbens. |
2011-08-02 |
2023-08-12 |
rat |
| Cassia N Cearley, Kelly Blindheim, Barbara A Sorg, James M Krueger, Lynn Churchil. Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochemical research. vol 36. issue 4. 2011-08-02. PMID:21399909. |
acute exposure of cocaine at 5 mg/kg at dark onset also increased the number of il1β-immunoreactive astrocytes in layer i-v of the prefrontal cortex, somatosensory cortex and nucleus accumbens. |
2011-08-02 |
2023-08-12 |
rat |
| Kuei-Ying Lin, Chianfang G Cherng, Fu-Rong Yang, Li-Ching Lin, Ru-Band Lu, Lung Y. Memantine abolishes the formation of cocaine-induced conditioned place preference possibly via its IL-6-modulating effect in medial prefrontal cortex. Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21277908. |
three consecutive days of cocaine conditioning increased interleukin-6 (il-6) but decreased tumor necrosis factor (tnf-α) levels in medial prefrontal cortex (mpfc) and nucleus accumbens (acb). |
2011-07-15 |
2023-08-12 |
mouse |
| Vijay Chandrasekar, Jean-Luc Dreye. The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. Frontiers in behavioral neuroscience. vol 4. 2011-07-14. PMID:20407577. |
brain-specific neural-zinc-finger transcription factor-2b (nzf2b/7zfmyt1) is induced in the mesolimbic dopaminergic region after chronic cocaine exposure and lentiviral-mediated expression of nzf2b/7zfmyt1 in the nucleus accumbens results in decreased locomotor activity (chandrasekar and dreyer, 2010). |
2011-07-14 |
2023-08-12 |
rat |
| Vijay Chandrasekar, Jean-Luc Dreye. The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. Frontiers in behavioral neuroscience. vol 4. 2011-07-14. PMID:20407577. |
localized expression of nzf2b/7zfmyt1 in the nucleus accumbens resulted in attenuated cocaine self-administration, whereas silencing this transcription factor with lentiviruses expressing sirnas increased the animal's motivation to self-infuse cocaine. |
2011-07-14 |
2023-08-12 |
rat |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. |
2011-06-15 |
2023-08-12 |
mouse |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
neuroadaptation in the nucleus accumbens (nac), a central component of the mesolimbic dopamine (da) system, has been implicated in the development of cocaine-induced psychomotor sensitization and relapse to cocaine seeking. |
2011-06-15 |
2023-08-12 |
mouse |
| Kathryn J Reissner, Joachim D Uys, John H Schwacke, Susanna Comte-Walters, Jennifer L Rutherford-Bethard, Thomas E Dunn, Joe B Blumer, Kevin L Schey, Peter W Kaliva. AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490206. |
to identify candidate proteins in the nucleus accumbens (nac) as potential pharmacotherapeutic targets for treating cocaine addition, an 8-plex itraq (isobaric tag for relative and absolute quantitation) proteomic screen was performed using nac tissue obtained from rats trained to self-administer cocaine followed by extinction training. |
2011-06-13 |
2023-08-12 |
human |
| James E McCutcheon, Xiaoting Wang, Kuei Y Tseng, Marina E Wolf, Michela Marinell. Calcium-permeable AMPA receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490215. |
calcium-permeable ampa receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine. |
2011-06-13 |
2023-08-12 |
mouse |
| James E McCutcheon, Xiaoting Wang, Kuei Y Tseng, Marina E Wolf, Michela Marinell. Calcium-permeable AMPA receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490215. |
repeated noncontingent cocaine injections, which lead to behavioral sensitization, increase ampa receptor (ampar) transmission in the rodent nucleus accumbens (nac) in a withdrawal-dependent manner. |
2011-06-13 |
2023-08-12 |
mouse |
| Avi E Zayara, Gregor McIver, Paola N Valdivia, Kevin D Lominac, Andrew C McCreary, Karen K Szumlinsk. Blockade of nucleus accumbens 5-HT2A and 5-HT2C receptors prevents the expression of cocaine-induced behavioral and neurochemical sensitization in rats. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20814782. |
the serotonin 5-ht(2a) and 5-ht(2c) receptors regulate the capacity of acute cocaine to augment behavior and monoamine levels within the nucleus accumbens (nac), a brain region involved in cocaine's addictive and psychotogenic properties. |
2011-05-24 |
2023-08-12 |
rat |
| Lionel Host, Jean-Bernard Dietrich, Delphine Carouge, Dominique Aunis, Jean Zwille. Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition. Journal of psychopharmacology (Oxford, England). vol 25. issue 2. 2011-05-11. PMID:19939859. |
in the present study, we investigated alterations in gene expression patterns in the anterior cingulate cortex, caudate-putamen and nucleus accumbens of rats self-administering cocaine and treated with trichostatin a. |
2011-05-11 |
2023-08-12 |
rat |
| Judy Yee, Katie R Famous, Thomas J Hopkins, Michael C McMullen, R Christopher Pierce, Heath D Schmid. Muscarinic acetylcholine receptors in the nucleus accumbens core and shell contribute to cocaine priming-induced reinstatement of drug seeking. European journal of pharmacology. vol 650. issue 2-3. 2011-05-02. PMID:21034738. |
muscarinic acetylcholine receptors in the nucleus accumbens play an important role in mediating the reinforcing effects of cocaine. |
2011-05-02 |
2023-08-12 |
human |
| Judy Yee, Katie R Famous, Thomas J Hopkins, Michael C McMullen, R Christopher Pierce, Heath D Schmid. Muscarinic acetylcholine receptors in the nucleus accumbens core and shell contribute to cocaine priming-induced reinstatement of drug seeking. European journal of pharmacology. vol 650. issue 2-3. 2011-05-02. PMID:21034738. |
taken together, these results indicate that cocaine priming-induced reinstatement is mediated, in part, by increased signaling through muscarinic acetylcholine receptors in the shell subregion of the nucleus accumbens. |
2011-05-02 |
2023-08-12 |
human |
| Ping Mu, Peter A Neumann, Jaak Panksepp, Oliver M Schlüter, Yan Don. Exposure to cocaine alters dynorphin-mediated regulation of excitatory synaptic transmission in nucleus accumbens neurons. Biological psychiatry. vol 69. issue 3. 2011-04-28. PMID:21030009. |
exposure to cocaine alters dynorphin-mediated regulation of excitatory synaptic transmission in nucleus accumbens neurons. |
2011-04-28 |
2023-08-12 |
Not clear |
| Frédéric Boyer, Eric Balado, Pier V Piazza, Jean-Luc Dreyer, Véronique Deroche-Gamone. A decrease in gamma-synuclein expression within the nucleus accumbens increases cocaine intravenous self-administration in the rat. Addiction biology. vol 16. issue 1. 2011-04-25. PMID:20579003. |
a decrease in gamma-synuclein expression within the nucleus accumbens increases cocaine intravenous self-administration in the rat. |
2011-04-25 |
2023-08-12 |
rat |
| Frédéric Boyer, Eric Balado, Pier V Piazza, Jean-Luc Dreyer, Véronique Deroche-Gamone. A decrease in gamma-synuclein expression within the nucleus accumbens increases cocaine intravenous self-administration in the rat. Addiction biology. vol 16. issue 1. 2011-04-25. PMID:20579003. |
in the rat, sirnas targeting gsyn expression were injected in the nucleus accumbens and cocaine reinforcing effects were evaluated by means of intravenous self-administration. |
2011-04-25 |
2023-08-12 |
rat |
| M Beyene, R M Carelli, R M Wightma. Cue-evoked dopamine release in the nucleus accumbens shell tracks reinforcer magnitude during intracranial self-stimulation. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600644. |
it has previously been shown, using fast-scan cyclic voltammetry in behaving rats, that cues predicting a variety of reinforcers including food/water, cocaine or intracranial self-stimulation (icss) elicit time-locked transient fluctuations in dopamine concentration in the nucleus accumbens (nac) shell. |
2011-04-18 |
2023-08-12 |
rat |
| Ian Maze, Jian Feng, Matthew B Wilkinson, HaoSheng Sun, Li Shen, Eric J Nestle. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21300862. |
cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. |
2011-04-14 |
2023-08-12 |
Not clear |
| Ian Maze, Jian Feng, Matthew B Wilkinson, HaoSheng Sun, Li Shen, Eric J Nestle. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21300862. |
here, we report that cocaine dramatically and dynamically alters heterochromatic histone h3 lysine 9 trimethylation (h3k9me3) in the nucleus accumbens (nac), a key brain reward region. |
2011-04-14 |
2023-08-12 |
Not clear |