| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juhyun Kim, Bong-Hyun Park, Joo Han Lee, Sang Ki Park, Joung-Hun Ki. Cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21377654. |
cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine. |
2011-09-12 |
2023-08-12 |
Not clear |
| Eisuke Koya, Bruce T Hop. Cocaine and synaptic alterations in the nucleus accumbens. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21550434. |
cocaine and synaptic alterations in the nucleus accumbens. |
2011-09-12 |
2023-08-12 |
Not clear |
| Klaus A Miczek, Ella M Nikulina, Akiko Shimamoto, Herbert E Covingto. Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 27. 2011-09-09. PMID:21734276. |
these stress experiences result in (1) increased intravenous cocaine self-administration under a fixed ratio schedule with prolonged binge-like access in episodically defeated intruder rats but suppressed cocaine intake by continuously subordinate rats; (2) deteriorated sugar preference and intake and decreased exploratory behavior in subordinate, but not intermittently defeated, rats; and (3) a sensitized dopamine (da) response in the nucleus accumbens via in vivo microdialysis and increased tegmental brain-derived neural growth factor (bdnf) in episodically defeated rats, whereas the continuously subordinate rats show suppression of the da and bdnf responses. |
2011-09-09 |
2023-08-12 |
rat |
| Stephan Lammel, Daniela I Ion, Jochen Roeper, Robert C Malenk. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron. vol 70. issue 5. 2011-08-23. PMID:21658580. |
administration of cocaine selectively modified excitatory synapses on da cells projecting to nucleus accumbens (nac) medial shell while an aversive stimulus selectively modified synapses on da cells projecting to medial prefrontal cortex. |
2011-08-23 |
2023-08-12 |
mouse |
| Cassia N Cearley, Kelly Blindheim, Barbara A Sorg, James M Krueger, Lynn Churchil. Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochemical research. vol 36. issue 4. 2011-08-02. PMID:21399909. |
acute cocaine increases interleukin-1β mrna and immunoreactive cells in the cortex and nucleus accumbens. |
2011-08-02 |
2023-08-12 |
rat |
| Cassia N Cearley, Kelly Blindheim, Barbara A Sorg, James M Krueger, Lynn Churchil. Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochemical research. vol 36. issue 4. 2011-08-02. PMID:21399909. |
il1β mrna levels after an acute exposure to cocaine (5 mg/kg, ip) at dark onset were significantly higher than those obtained from rats sacrificed after an acute exposure to saline in the piriform and somatosensory cortex, and nucleus accumbens. |
2011-08-02 |
2023-08-12 |
rat |
| Cassia N Cearley, Kelly Blindheim, Barbara A Sorg, James M Krueger, Lynn Churchil. Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochemical research. vol 36. issue 4. 2011-08-02. PMID:21399909. |
acute exposure of cocaine at 5 mg/kg at dark onset also increased the number of il1β-immunoreactive astrocytes in layer i-v of the prefrontal cortex, somatosensory cortex and nucleus accumbens. |
2011-08-02 |
2023-08-12 |
rat |
| Kuei-Ying Lin, Chianfang G Cherng, Fu-Rong Yang, Li-Ching Lin, Ru-Band Lu, Lung Y. Memantine abolishes the formation of cocaine-induced conditioned place preference possibly via its IL-6-modulating effect in medial prefrontal cortex. Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21277908. |
three consecutive days of cocaine conditioning increased interleukin-6 (il-6) but decreased tumor necrosis factor (tnf-α) levels in medial prefrontal cortex (mpfc) and nucleus accumbens (acb). |
2011-07-15 |
2023-08-12 |
mouse |
| Vijay Chandrasekar, Jean-Luc Dreye. The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. Frontiers in behavioral neuroscience. vol 4. 2011-07-14. PMID:20407577. |
brain-specific neural-zinc-finger transcription factor-2b (nzf2b/7zfmyt1) is induced in the mesolimbic dopaminergic region after chronic cocaine exposure and lentiviral-mediated expression of nzf2b/7zfmyt1 in the nucleus accumbens results in decreased locomotor activity (chandrasekar and dreyer, 2010). |
2011-07-14 |
2023-08-12 |
rat |
| Vijay Chandrasekar, Jean-Luc Dreye. The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. Frontiers in behavioral neuroscience. vol 4. 2011-07-14. PMID:20407577. |
localized expression of nzf2b/7zfmyt1 in the nucleus accumbens resulted in attenuated cocaine self-administration, whereas silencing this transcription factor with lentiviruses expressing sirnas increased the animal's motivation to self-infuse cocaine. |
2011-07-14 |
2023-08-12 |
rat |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. |
2011-06-15 |
2023-08-12 |
mouse |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
neuroadaptation in the nucleus accumbens (nac), a central component of the mesolimbic dopamine (da) system, has been implicated in the development of cocaine-induced psychomotor sensitization and relapse to cocaine seeking. |
2011-06-15 |
2023-08-12 |
mouse |
| Kathryn J Reissner, Joachim D Uys, John H Schwacke, Susanna Comte-Walters, Jennifer L Rutherford-Bethard, Thomas E Dunn, Joe B Blumer, Kevin L Schey, Peter W Kaliva. AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490206. |
to identify candidate proteins in the nucleus accumbens (nac) as potential pharmacotherapeutic targets for treating cocaine addition, an 8-plex itraq (isobaric tag for relative and absolute quantitation) proteomic screen was performed using nac tissue obtained from rats trained to self-administer cocaine followed by extinction training. |
2011-06-13 |
2023-08-12 |
human |
| James E McCutcheon, Xiaoting Wang, Kuei Y Tseng, Marina E Wolf, Michela Marinell. Calcium-permeable AMPA receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490215. |
calcium-permeable ampa receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine. |
2011-06-13 |
2023-08-12 |
mouse |
| James E McCutcheon, Xiaoting Wang, Kuei Y Tseng, Marina E Wolf, Michela Marinell. Calcium-permeable AMPA receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490215. |
repeated noncontingent cocaine injections, which lead to behavioral sensitization, increase ampa receptor (ampar) transmission in the rodent nucleus accumbens (nac) in a withdrawal-dependent manner. |
2011-06-13 |
2023-08-12 |
mouse |
| Avi E Zayara, Gregor McIver, Paola N Valdivia, Kevin D Lominac, Andrew C McCreary, Karen K Szumlinsk. Blockade of nucleus accumbens 5-HT2A and 5-HT2C receptors prevents the expression of cocaine-induced behavioral and neurochemical sensitization in rats. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20814782. |
the serotonin 5-ht(2a) and 5-ht(2c) receptors regulate the capacity of acute cocaine to augment behavior and monoamine levels within the nucleus accumbens (nac), a brain region involved in cocaine's addictive and psychotogenic properties. |
2011-05-24 |
2023-08-12 |
rat |
| Lionel Host, Jean-Bernard Dietrich, Delphine Carouge, Dominique Aunis, Jean Zwille. Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition. Journal of psychopharmacology (Oxford, England). vol 25. issue 2. 2011-05-11. PMID:19939859. |
in the present study, we investigated alterations in gene expression patterns in the anterior cingulate cortex, caudate-putamen and nucleus accumbens of rats self-administering cocaine and treated with trichostatin a. |
2011-05-11 |
2023-08-12 |
rat |
| Judy Yee, Katie R Famous, Thomas J Hopkins, Michael C McMullen, R Christopher Pierce, Heath D Schmid. Muscarinic acetylcholine receptors in the nucleus accumbens core and shell contribute to cocaine priming-induced reinstatement of drug seeking. European journal of pharmacology. vol 650. issue 2-3. 2011-05-02. PMID:21034738. |
muscarinic acetylcholine receptors in the nucleus accumbens play an important role in mediating the reinforcing effects of cocaine. |
2011-05-02 |
2023-08-12 |
human |
| Judy Yee, Katie R Famous, Thomas J Hopkins, Michael C McMullen, R Christopher Pierce, Heath D Schmid. Muscarinic acetylcholine receptors in the nucleus accumbens core and shell contribute to cocaine priming-induced reinstatement of drug seeking. European journal of pharmacology. vol 650. issue 2-3. 2011-05-02. PMID:21034738. |
taken together, these results indicate that cocaine priming-induced reinstatement is mediated, in part, by increased signaling through muscarinic acetylcholine receptors in the shell subregion of the nucleus accumbens. |
2011-05-02 |
2023-08-12 |
human |
| Ping Mu, Peter A Neumann, Jaak Panksepp, Oliver M Schlüter, Yan Don. Exposure to cocaine alters dynorphin-mediated regulation of excitatory synaptic transmission in nucleus accumbens neurons. Biological psychiatry. vol 69. issue 3. 2011-04-28. PMID:21030009. |
exposure to cocaine alters dynorphin-mediated regulation of excitatory synaptic transmission in nucleus accumbens neurons. |
2011-04-28 |
2023-08-12 |
Not clear |