| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Satoru M Sato, Anne Marie Wissman, Andrew F McCollum, Catherine S Woolle. Quantitative mapping of cocaine-induced ΔFosB expression in the striatum of male and female rats. PloS one. vol 6. issue 7. 2011-11-04. PMID:21747956. |
western blot and immunohistochemical analyses indicated that basal levels of Δfosb were higher in the nucleus accumbens than the dorsal striatum, but that the effect of cocaine on Δfosb was greater in the dorsal striatum. |
2011-11-04 |
2023-08-12 |
rat |
| Satoru M Sato, Anne Marie Wissman, Andrew F McCollum, Catherine S Woolle. Quantitative mapping of cocaine-induced ΔFosB expression in the striatum of male and female rats. PloS one. vol 6. issue 7. 2011-11-04. PMID:21747956. |
immunostaining showed that the effect of cocaine in both the dorsal striatum and nucleus accumbens was primarily to increase the intensity of Δfosb immunoreactivity in individual neurons, rather than to increase the number of cells that express Δfosb. |
2011-11-04 |
2023-08-12 |
rat |
| Herbert E Covington, Ian Maze, HaoSheng Sun, Howard M Bomze, Kristine D DeMaio, Emma Y Wu, David M Dietz, Mary Kay Lobo, Subroto Ghose, Ezekiel Mouzon, Rachael L Neve, Carol A Tamminga, Eric J Nestle. A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron. vol 71. issue 4. 2011-10-25. PMID:21867882. |
here, we identify repressive histone methylation in nucleus accumbens (nac), an important brain reward region, as a key mechanism linking cocaine exposure to increased stress vulnerability. |
2011-10-25 |
2023-08-12 |
mouse |
| Michael P Saddoris, Alice Stamatakis, Regina M Carell. Neural correlates of Pavlovian-to-instrumental transfer in the nucleus accumbens shell are selectively potentiated following cocaine self-administration. The European journal of neuroscience. vol 33. issue 12. 2011-10-24. PMID:21507084. |
other groups, following pavlovian and instrumental conditioning, were subsequently trained to self-administer cocaine with nosepoke responses, or received yoked saline infusions and nosepoked for water rewards, and then performed pit while electrophysiological recordings were taken in the nucleus accumbens. |
2011-10-24 |
2023-08-12 |
rat |
| Kensuke Kimura, Takatoshi Hikida, Satoshi Yawata, Takashi Yamaguchi, Shigetada Nakanish. Pathway-specific engagement of ephrinA5-EphA4/EphA5 system of the substantia nigra pars reticulata in cocaine-induced responses. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 24. 2011-09-29. PMID:21628570. |
the nucleus accumbens (nac) serves as a key neural substrate that controls acute and adaptive behavioral responses to cocaine administration. |
2011-09-29 |
2023-08-12 |
mouse |
| Marina E Wol. Regulation of AMPA receptor trafficking in the nucleus accumbens by dopamine and cocaine. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20361291. |
regulation of ampa receptor trafficking in the nucleus accumbens by dopamine and cocaine. |
2011-09-15 |
2023-08-12 |
rat |
| Shigenobu Toda, Haowei Shen, Peter W Kaliva. Inhibition of actin polymerization prevents cocaine-induced changes in spine morphology in the nucleus accumbens. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20401643. |
withdrawal from daily cocaine administration causes an increase in actin cycling and increases spine head diameter in medium spiny neurons from the core of the nucleus accumbens. |
2011-09-15 |
2023-08-12 |
human |
| Dustin K Van Dolah, Li-Min Mao, Christopher Shaffer, Ming-Lei Guo, Eugene E Fibuch, Xiang-Ping Chu, Shilpa Buch, John Q Wan. Reversible palmitoylation regulates surface stability of AMPA receptors in the nucleus accumbens in response to cocaine in vivo. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21216391. |
reversible palmitoylation regulates surface stability of ampa receptors in the nucleus accumbens in response to cocaine in vivo. |
2011-09-12 |
2023-08-12 |
Not clear |
| Juhyun Kim, Bong-Hyun Park, Joo Han Lee, Sang Ki Park, Joung-Hun Ki. Cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21377654. |
cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine. |
2011-09-12 |
2023-08-12 |
Not clear |
| Eisuke Koya, Bruce T Hop. Cocaine and synaptic alterations in the nucleus accumbens. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21550434. |
cocaine and synaptic alterations in the nucleus accumbens. |
2011-09-12 |
2023-08-12 |
Not clear |
| Klaus A Miczek, Ella M Nikulina, Akiko Shimamoto, Herbert E Covingto. Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 27. 2011-09-09. PMID:21734276. |
these stress experiences result in (1) increased intravenous cocaine self-administration under a fixed ratio schedule with prolonged binge-like access in episodically defeated intruder rats but suppressed cocaine intake by continuously subordinate rats; (2) deteriorated sugar preference and intake and decreased exploratory behavior in subordinate, but not intermittently defeated, rats; and (3) a sensitized dopamine (da) response in the nucleus accumbens via in vivo microdialysis and increased tegmental brain-derived neural growth factor (bdnf) in episodically defeated rats, whereas the continuously subordinate rats show suppression of the da and bdnf responses. |
2011-09-09 |
2023-08-12 |
rat |
| Stephan Lammel, Daniela I Ion, Jochen Roeper, Robert C Malenk. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron. vol 70. issue 5. 2011-08-23. PMID:21658580. |
administration of cocaine selectively modified excitatory synapses on da cells projecting to nucleus accumbens (nac) medial shell while an aversive stimulus selectively modified synapses on da cells projecting to medial prefrontal cortex. |
2011-08-23 |
2023-08-12 |
mouse |
| Cassia N Cearley, Kelly Blindheim, Barbara A Sorg, James M Krueger, Lynn Churchil. Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochemical research. vol 36. issue 4. 2011-08-02. PMID:21399909. |
acute cocaine increases interleukin-1β mrna and immunoreactive cells in the cortex and nucleus accumbens. |
2011-08-02 |
2023-08-12 |
rat |
| Cassia N Cearley, Kelly Blindheim, Barbara A Sorg, James M Krueger, Lynn Churchil. Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochemical research. vol 36. issue 4. 2011-08-02. PMID:21399909. |
il1β mrna levels after an acute exposure to cocaine (5 mg/kg, ip) at dark onset were significantly higher than those obtained from rats sacrificed after an acute exposure to saline in the piriform and somatosensory cortex, and nucleus accumbens. |
2011-08-02 |
2023-08-12 |
rat |
| Cassia N Cearley, Kelly Blindheim, Barbara A Sorg, James M Krueger, Lynn Churchil. Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens. Neurochemical research. vol 36. issue 4. 2011-08-02. PMID:21399909. |
acute exposure of cocaine at 5 mg/kg at dark onset also increased the number of il1β-immunoreactive astrocytes in layer i-v of the prefrontal cortex, somatosensory cortex and nucleus accumbens. |
2011-08-02 |
2023-08-12 |
rat |
| Kuei-Ying Lin, Chianfang G Cherng, Fu-Rong Yang, Li-Ching Lin, Ru-Band Lu, Lung Y. Memantine abolishes the formation of cocaine-induced conditioned place preference possibly via its IL-6-modulating effect in medial prefrontal cortex. Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21277908. |
three consecutive days of cocaine conditioning increased interleukin-6 (il-6) but decreased tumor necrosis factor (tnf-α) levels in medial prefrontal cortex (mpfc) and nucleus accumbens (acb). |
2011-07-15 |
2023-08-12 |
mouse |
| Vijay Chandrasekar, Jean-Luc Dreye. The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. Frontiers in behavioral neuroscience. vol 4. 2011-07-14. PMID:20407577. |
brain-specific neural-zinc-finger transcription factor-2b (nzf2b/7zfmyt1) is induced in the mesolimbic dopaminergic region after chronic cocaine exposure and lentiviral-mediated expression of nzf2b/7zfmyt1 in the nucleus accumbens results in decreased locomotor activity (chandrasekar and dreyer, 2010). |
2011-07-14 |
2023-08-12 |
rat |
| Vijay Chandrasekar, Jean-Luc Dreye. The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. Frontiers in behavioral neuroscience. vol 4. 2011-07-14. PMID:20407577. |
localized expression of nzf2b/7zfmyt1 in the nucleus accumbens resulted in attenuated cocaine self-administration, whereas silencing this transcription factor with lentiviruses expressing sirnas increased the animal's motivation to self-infuse cocaine. |
2011-07-14 |
2023-08-12 |
rat |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. |
2011-06-15 |
2023-08-12 |
mouse |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
neuroadaptation in the nucleus accumbens (nac), a central component of the mesolimbic dopamine (da) system, has been implicated in the development of cocaine-induced psychomotor sensitization and relapse to cocaine seeking. |
2011-06-15 |
2023-08-12 |
mouse |