| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samuel Asensio, Maria J Romero, Carmina Palau, Amparo Sanchez, Isabel Senabre, Julia L Morales, Raquel Carcelen, Francisco J Romer. Altered neural response of the appetitive emotional system in cocaine addiction: an fMRI Study. Addiction biology. vol 15. issue 4. 2011-02-28. PMID:20579005. |
however, compared with controls, the cocaine group showed a significant hypoactivation of the dorsal and ventral striatum (including the nucleus accumbens), thalamus, parietal cortex and dorso-medial prefrontal cortex (dmpfc) when processing pleasant pictures. |
2011-02-28 |
2023-08-12 |
human |
| Timothy W Whitfield, Xiangdang Shi, Wei-Lun Sun, Jacqueline F McGint. The suppressive effect of an intra-prefrontal cortical infusion of BDNF on cocaine-seeking is Trk receptor and extracellular signal-regulated protein kinase mitogen-activated protein kinase dependent. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 3. 2011-02-23. PMID:21248106. |
we have previously demonstrated that infusion of bdnf into the dorsomedial prefrontal cortex (dmpfc) immediately after the last of 10 cocaine sa sessions attenuates contextual, cue- and cocaine prime-induced reinstatement of cocaine-seeking (berglind et al., 2007) and normalizes cocaine-induced disruption of glutamatergic transmission in the nucleus accumbens (berglind et al., 2009). |
2011-02-23 |
2023-08-12 |
rat |
| Marina E Wolf, Carrie R Ferrari. AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine. Neuroscience and biobehavioral reviews. vol 35. issue 2. 2011-02-17. PMID:20109488. |
ampa receptor plasticity in the nucleus accumbens after repeated exposure to cocaine. |
2011-02-17 |
2023-08-12 |
Not clear |
| Kaili Anier, Kristina Malinovskaja, Anu Aonurm-Helm, Alexander Zharkovsky, Anti Kald. DNA methylation regulates cocaine-induced behavioral sensitization in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 12. 2011-02-16. PMID:20720536. |
we report that acute cocaine treatment caused an upregulation of dnmt3a and dnmt3b gene expression in the nucleus accumbens (nac). |
2011-02-16 |
2023-08-12 |
mouse |
| Thomas P Giordano, Thomas F Tropea, Shirish S Satpute, Martina J Sinnegger-Brauns, Joerg Striessnig, Barry E Kosofsky, Anjali M Rajadhyaksh. Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 50. 2011-02-09. PMID:21159975. |
molecular studies to further elucidate the role of ca(v)1.2 versus ca(v)1.3 ltccs in activating signaling pathways in the nucleus accumbens (nac) of drug-naive versus drug-preexposed mice examined 14 d later revealed that an acute amphetamine and cocaine challenge in drug-naive mice increases ser133 camp response element-binding protein (creb) phosphorylation in the nac via ca(v)1.3 channels and via a dopamine d(1)-dependent mechanism, independent of the extracellular signal-regulated kinase (erk) pathway, an important mediator of psychostimulant-induced plasticity. |
2011-02-09 |
2023-08-12 |
mouse |
| A W Lasek, D Kapfhamer, V Kharazia, J Gesch, F Giorgetti, U Heberlei. Lmo4 in the nucleus accumbens regulates cocaine sensitivity. Genes, brain, and behavior. vol 9. issue 7. 2011-02-08. PMID:20618444. |
lmo4 in the nucleus accumbens regulates cocaine sensitivity. |
2011-02-08 |
2023-08-12 |
mouse |
| Mark C Moffett, Jane Song, Michael J Kuha. CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506412. |
previously, our laboratory demonstrated that injections of cart peptide (cart 55-102) into the nucleus accumbens (nac) attenuated both cocaine- and dopamine-induced increases in locomotor activity (lma), and attenuated cocaine reward as well. |
2011-02-04 |
2023-08-12 |
rat |
| Carrie R Ferrario, Xuan Li, Marina E Wol. Effects of acute cocaine or dopamine receptor agonists on AMPA receptor distribution in the rat nucleus accumbens. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506566. |
effects of acute cocaine or dopamine receptor agonists on ampa receptor distribution in the rat nucleus accumbens. |
2011-02-04 |
2023-08-12 |
rat |
| Carrie R Ferrario, Xuan Li, Marina E Wol. Effects of acute cocaine or dopamine receptor agonists on AMPA receptor distribution in the rat nucleus accumbens. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506566. |
changes in α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor (ampar) surface expression in the rodent nucleus accumbens (nac) are produced by cocaine exposure and implicated in addiction-related behaviors. |
2011-02-04 |
2023-08-12 |
rat |
| Paul F Kramer, Christine H Christensen, Lisa A Hazelwood, Alice Dobi, Roland Bock, David R Sibley, Yolanda Mateo, Veronica A Alvare. Dopamine D2 receptor overexpression alters behavior and physiology in Drd2-EGFP mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 1. 2011-02-04. PMID:21209197. |
dopamine (da) transients evoked by stimulation in the nucleus accumbens showed slower clearance in drd2-egfp mice, and cocaine actions on da clearance were impaired in these mice. |
2011-02-04 |
2023-08-12 |
mouse |
| Garret D Stuber, F Woodward Hopf, Kay M Tye, Billy T Chen, Antonello Bonc. Neuroplastic alterations in the limbic system following cocaine or alcohol exposure. Current topics in behavioral neurosciences. vol 3. 2011-01-20. PMID:21161748. |
both the dopaminergic neurons of the ventral tegmental area as well medium spiny neurons in nucleus accumbens show enhanced excitatory synaptic strength following passive or active exposure to drugs such as cocaine and alcohol. |
2011-01-20 |
2023-08-12 |
Not clear |
| Marcel M van Gaalen, Dustin Schetters, Anton N M Schoffelmeer, Taco J De Vrie. 5-HT6 antagonism attenuates cue-induced relapse to cocaine seeking without affecting cocaine reinforcement. The international journal of neuropsychopharmacology. vol 13. issue 7. 2011-01-10. PMID:20426879. |
5-ht6 receptors (5-ht6rs) are abundantly expressed in brain areas such as the nucleus accumbens and prefrontal cortex, which are critically involved in cocaine reinforcement and relapse. |
2011-01-10 |
2023-08-12 |
rat |
| George A Rogge, Li-Ling Shen, Michael J Kuha. Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter. Brain research. vol 1344. 2011-01-10. PMID:20451507. |
both over expression of cyclic amp response element binding protein (creb) in the nucleus accumbens (nac), and intra-accumbal injection of cocaine- and amphetamine-regulated transcript (cart) peptides, have been shown to decrease cocaine reward. |
2011-01-10 |
2023-08-12 |
rat |
| K Y Salas-Ramirez, M Frankfurt, A Alexander, V N Luine, E Friedma. Prenatal cocaine exposure increases anxiety, impairs cognitive function and increases dendritic spine density in adult rats: influence of sex. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20553818. |
in addition, gestational cocaine increased dendritic spine density in the prefrontal cortex and nucleus accumbens in both genders, but only females had increased spine density in the ca1 region of the hippocampus. |
2010-12-16 |
2023-08-12 |
human |
| Chinwe A Nwaneshiudu, Ellen M Unterwal. NK-3 receptor antagonism prevents behavioral sensitization to cocaine: a role of glycogen synthase kinase-3 in the nucleus accumbens. Journal of neurochemistry. vol 115. issue 3. 2010-12-02. PMID:20807318. |
nk-3 receptor antagonism prevents behavioral sensitization to cocaine: a role of glycogen synthase kinase-3 in the nucleus accumbens. |
2010-12-02 |
2023-08-12 |
mouse |
| Chinwe A Nwaneshiudu, Ellen M Unterwal. NK-3 receptor antagonism prevents behavioral sensitization to cocaine: a role of glycogen synthase kinase-3 in the nucleus accumbens. Journal of neurochemistry. vol 115. issue 3. 2010-12-02. PMID:20807318. |
collectively, these findings demonstrate the involvement of nk-3 receptors in development and expression of behavioral sensitization and in regulation of gsk3 activity in the nucleus accumbens after repeated cocaine. |
2010-12-02 |
2023-08-12 |
mouse |
| Nii A Addy, David P Daberkow, Jeremy N Ford, Paul A Garris, R Mark Wightma. Sensitization of rapid dopamine signaling in the nucleus accumbens core and shell after repeated cocaine in rats. Journal of neurophysiology. vol 104. issue 2. 2010-12-01. PMID:20554845. |
to study dopamine neurotransmission after 1-day withdrawal, we used fast-scan cyclic voltammetry (fscv) to determine whether repeated cocaine alters rapid dopamine release and uptake in the nucleus accumbens (nac) core and shell. |
2010-12-01 |
2023-08-12 |
human |
| Marina E Wol. The Bermuda Triangle of cocaine-induced neuroadaptations. Trends in neurosciences. vol 33. issue 9. 2010-11-26. PMID:20655604. |
activation of medium spiny neurons (msns) of the nucleus accumbens is critical for goal-directed behaviors including cocaine seeking. |
2010-11-26 |
2023-08-12 |
Not clear |
| Drew D Kiraly, Xin-Ming Ma, Christopher M Mazzone, Xiaonan Xin, Richard E Mains, Betty A Eippe. Behavioral and morphological responses to cocaine require kalirin7. Biological psychiatry. vol 68. issue 3. 2010-11-22. PMID:20452575. |
long-lasting increases in dendritic spine density and gene expression in the nucleus accumbens and in the ambulatory response to cocaine occur following chronic cocaine treatment. |
2010-11-22 |
2023-08-12 |
Not clear |
| Mary Kay Lobo, Herbert E Covington, Dipesh Chaudhury, Allyson K Friedman, HaoSheng Sun, Diane Damez-Werno, David M Dietz, Samir Zaman, Ja Wook Koo, Pamela J Kennedy, Ezekiell Mouzon, Murtaza Mogri, Rachael L Neve, Karl Deisseroth, Ming-Hu Han, Eric J Nestle. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (New York, N.Y.). vol 330. issue 6002. 2010-11-10. PMID:20947769. |
the nucleus accumbens is a key mediator of cocaine reward, but the distinct roles of the two subpopulations of nucleus accumbens projection neurons, those expressing dopamine d1 versus d2 receptors, are poorly understood. |
2010-11-10 |
2023-08-12 |
Not clear |