| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Heath D Schmidt, Katie R Famous, R C Pierc. The limbic circuitry underlying cocaine seeking encompasses the PPTg/LDT. The European journal of neuroscience. vol 30. issue 7. 2010-01-18. PMID:19788581. |
the direct glutamatergic projection from the medial prefrontal cortex (mpfc) to the nucleus accumbens plays a critical role in mediating the reinstatement of cocaine seeking behavior. |
2010-01-18 |
2023-08-12 |
rat |
| Christina Gianoulaki. Endogenous opioids and addiction to alcohol and other drugs of abuse. Current topics in medicinal chemistry. vol 9. issue 11. 2010-01-11. PMID:19747123. |
it has also been shown that regardless of their initial site of action many drugs of abuse, such as morphine, nicotine, cocaine, alcohol and amphetamines, induce an increase in the extracellular concentration of dopamine in the nucleus accumbens. |
2010-01-11 |
2023-08-12 |
Not clear |
| Chun-Mei Xu, Jun Wang, Ping Wu, Wei-Li Zhu, Qian-Qian Li, Yan-Xue Xue, Hai-Fen Zhai, Jie Shi, Lin L. Glycogen synthase kinase 3beta in the nucleus accumbens core mediates cocaine-induced behavioral sensitization. Journal of neurochemistry. vol 111. issue 6. 2010-01-08. PMID:19799712. |
the present study investigated the effects of chronic cocaine exposure on gsk-3beta activity in the nucleus accumbens (nac) and determined whether changes in gsk-3beta activity in the nac are associated with cocaine-induced locomotor sensitization. |
2010-01-08 |
2023-08-12 |
rat |
| Avery R Soderman, Ellen M Unterwal. Cocaine-induced mu opioid receptor occupancy within the striatum is mediated by dopamine D2 receptors. Brain research. vol 1296. 2009-12-29. PMID:19699185. |
previous studies by our laboratory have demonstrated that the mu opioid receptor antagonist, ctap, blocks the rewarding effects of cocaine when it is injected directly into the nucleus accumbens or ventral tegmental area (vta). |
2009-12-29 |
2023-08-12 |
rat |
| Avery R Soderman, Ellen M Unterwal. Cocaine-induced mu opioid receptor occupancy within the striatum is mediated by dopamine D2 receptors. Brain research. vol 1296. 2009-12-29. PMID:19699185. |
this finding suggests that cocaine is causing the release of endogenous opioid peptides which activate mu opioid receptors within the nucleus accumbens and vta. |
2009-12-29 |
2023-08-12 |
rat |
| Avery R Soderman, Ellen M Unterwal. Cocaine-induced mu opioid receptor occupancy within the striatum is mediated by dopamine D2 receptors. Brain research. vol 1296. 2009-12-29. PMID:19699185. |
these results suggest that cocaine, acting via d2 dopamine receptors, can cause the release of an endogenous opioid peptide that binds to mu opioid receptors within the nucleus accumbens. |
2009-12-29 |
2023-08-12 |
rat |
| Amy C Janes, Kathleen M Kantak, James A Cherr. The involvement of type IV phosphodiesterases in cocaine-induced sensitization and subsequent pERK expression in the mouse nucleus accumbens. Psychopharmacology. vol 206. issue 2. 2009-12-22. PMID:19588125. |
cocaine exposure produces sensitization that is partly mediated by cyclic adenosine monophosphate (camp) pathways within the nucleus accumbens (nac). |
2009-12-22 |
2023-08-12 |
mouse |
| Anna M Nelson, Gaynor A Larson, Nancy R Zahnise. Low or high cocaine responding rats differ in striatal extracellular dopamine levels and dopamine transporter number. The Journal of pharmacology and experimental therapeutics. vol 331. issue 3. 2009-12-22. PMID:19729579. |
paralleling their locomotor profiles, lcrs and hcrs had similar basal extracellular da levels in dorsal striatum (dstr) and nucleus accumbens (nac); after acute cocaine injection (10 mg/kg i.p. |
2009-12-22 |
2023-08-12 |
rat |
| Vitaly Palamarchouk, Gennady Smagin, Nicholas E Goeder. Self-administered and passive cocaine infusions produce different effects on corticosterone concentrations in the medial prefrontal cortex (MPC) of rats. Pharmacology, biochemistry, and behavior. vol 94. issue 1. 2009-12-17. PMID:19698740. |
in these experiments, we measured corticosterone in microdialysis samples collected from probes aimed at the medial prefrontal cortex, nucleus accumbens and basolateral amygdala in rats self-administering cocaine and receiving identical, passive infusions of cocaine or saline. |
2009-12-17 |
2023-08-12 |
rat |
| W Y Kim, S R Shin, S Kim, S Jeon, J-H Ki. Cocaine regulates ezrin-radixin-moesin proteins and RhoA signaling in the nucleus accumbens. Neuroscience. vol 163. issue 2. 2009-12-14. PMID:19580848. |
cocaine regulates ezrin-radixin-moesin proteins and rhoa signaling in the nucleus accumbens. |
2009-12-14 |
2023-08-12 |
rat |
| Jérémie Lavaur, Yann S Mineur, Marina R Picciott. The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780900. |
the membrane cytoskeletal protein adducin is phosphorylated by protein kinase c in d1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. |
2009-12-11 |
2023-08-12 |
Not clear |
| Jérémie Lavaur, Yann S Mineur, Marina R Picciott. The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780900. |
cocaine administration increases levels of f-actin in the nucleus accumbens and is associated with changes in the phosphorylation state of actin-binding proteins. |
2009-12-11 |
2023-08-12 |
Not clear |
| Jérémie Lavaur, Yann S Mineur, Marina R Picciott. The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780900. |
in the current study, we characterized the regulation of adducin phosphorylation in the nucleus accumbens and dorsal striatum in response to various regimen of cocaine. |
2009-12-11 |
2023-08-12 |
Not clear |
| Su-Mi Park, Ron P A Gaykema, Lisa E Goehle. How does immune challenge inhibit ingestion of palatable food? Evidence that systemic lipopolysaccharide treatment modulates key nodal points of feeding neurocircuitry. Brain, behavior, and immunity. vol 22. issue 8. 2009-11-17. PMID:18562160. |
sweetened milk ingestion was associated with increased numbers of c-fos positive neurons in the caudal core and shell of the nucleus accumbens (nac), the paraventricular thalamus (pvt), central nucleus of the amygdala (cea), the basal lateral amygdala (bla), in orexin-a containing neurons of the lateral hypothalamus (lh), and in cocaine and amphetamine regulated transcript (cart) neurons of the arcuate hypothalamus. |
2009-11-17 |
2023-08-12 |
Not clear |
| Ilana Roth-Deri, Alexander Friedman, Lital Abraham, Elad Lax, Yakov Flaumenhaft, Yahav Dikshtein, Gal Yadi. Antidepressant treatment facilitates dopamine release and drug seeking behavior in a genetic animal model of depression. The European journal of neuroscience. vol 30. issue 3. 2009-10-27. PMID:19614746. |
fsl rats exhibited low but dose-dependent increases in extracellular levels of dopamine in the nucleus accumbens after acute intravenous cocaine injection. |
2009-10-27 |
2023-08-12 |
rat |
| Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
regulation of dynamin 2 and g protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. |
2009-10-26 |
2023-08-12 |
rat |
| Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
acute binge-pattern cocaine administration produced a significant increase in both dynamin 2- and grk2-immunoreactivity (227% and 358% of control) in the nucleus accumbens and gkr2 (150% of control) in the caudate putamen. |
2009-10-26 |
2023-08-12 |
rat |
| Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
in contrast, dynamin 2 and grk2 were significantly decreased in the nucleus accumbens after chronic cocaine. |
2009-10-26 |
2023-08-12 |
rat |
| Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
pretreatment with either the dopamine (da) d1 receptor antagonist sch 23390 or d2 receptor antagonist eticlopride prior to acute cocaine blocked the upregulation of dynamin 2 and grk2 in the nucleus accumbens. |
2009-10-26 |
2023-08-12 |
rat |
| Joseph A Schroeder, Mary R McCafferty, Ellen M Unterwal. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562697. |
these results demonstrate that two proteins involved in receptor and transporter trafficking are selectively regulated in the nucleus accumbens following acute versus chronic cocaine exposure, and dopamine receptor activation is required for this regulation. |
2009-10-26 |
2023-08-12 |
rat |