All Relations between cocaine and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
K Y Salas-Ramirez, M Frankfurt, A Alexander, V N Luine, E Friedma. Prenatal cocaine exposure increases anxiety, impairs cognitive function and increases dendritic spine density in adult rats: influence of sex. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20553818. in addition, gestational cocaine increased dendritic spine density in the prefrontal cortex and nucleus accumbens in both genders, but only females had increased spine density in the ca1 region of the hippocampus. 2010-12-16 2023-08-12 human
Chinwe A Nwaneshiudu, Ellen M Unterwal. NK-3 receptor antagonism prevents behavioral sensitization to cocaine: a role of glycogen synthase kinase-3 in the nucleus accumbens. Journal of neurochemistry. vol 115. issue 3. 2010-12-02. PMID:20807318. nk-3 receptor antagonism prevents behavioral sensitization to cocaine: a role of glycogen synthase kinase-3 in the nucleus accumbens. 2010-12-02 2023-08-12 mouse
Chinwe A Nwaneshiudu, Ellen M Unterwal. NK-3 receptor antagonism prevents behavioral sensitization to cocaine: a role of glycogen synthase kinase-3 in the nucleus accumbens. Journal of neurochemistry. vol 115. issue 3. 2010-12-02. PMID:20807318. collectively, these findings demonstrate the involvement of nk-3 receptors in development and expression of behavioral sensitization and in regulation of gsk3 activity in the nucleus accumbens after repeated cocaine. 2010-12-02 2023-08-12 mouse
Nii A Addy, David P Daberkow, Jeremy N Ford, Paul A Garris, R Mark Wightma. Sensitization of rapid dopamine signaling in the nucleus accumbens core and shell after repeated cocaine in rats. Journal of neurophysiology. vol 104. issue 2. 2010-12-01. PMID:20554845. to study dopamine neurotransmission after 1-day withdrawal, we used fast-scan cyclic voltammetry (fscv) to determine whether repeated cocaine alters rapid dopamine release and uptake in the nucleus accumbens (nac) core and shell. 2010-12-01 2023-08-12 human
Marina E Wol. The Bermuda Triangle of cocaine-induced neuroadaptations. Trends in neurosciences. vol 33. issue 9. 2010-11-26. PMID:20655604. activation of medium spiny neurons (msns) of the nucleus accumbens is critical for goal-directed behaviors including cocaine seeking. 2010-11-26 2023-08-12 Not clear
Drew D Kiraly, Xin-Ming Ma, Christopher M Mazzone, Xiaonan Xin, Richard E Mains, Betty A Eippe. Behavioral and morphological responses to cocaine require kalirin7. Biological psychiatry. vol 68. issue 3. 2010-11-22. PMID:20452575. long-lasting increases in dendritic spine density and gene expression in the nucleus accumbens and in the ambulatory response to cocaine occur following chronic cocaine treatment. 2010-11-22 2023-08-12 Not clear
Mary Kay Lobo, Herbert E Covington, Dipesh Chaudhury, Allyson K Friedman, HaoSheng Sun, Diane Damez-Werno, David M Dietz, Samir Zaman, Ja Wook Koo, Pamela J Kennedy, Ezekiell Mouzon, Murtaza Mogri, Rachael L Neve, Karl Deisseroth, Ming-Hu Han, Eric J Nestle. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (New York, N.Y.). vol 330. issue 6002. 2010-11-10. PMID:20947769. the nucleus accumbens is a key mediator of cocaine reward, but the distinct roles of the two subpopulations of nucleus accumbens projection neurons, those expressing dopamine d1 versus d2 receptors, are poorly understood. 2010-11-10 2023-08-12 Not clear
Mary Kay Lobo, Herbert E Covington, Dipesh Chaudhury, Allyson K Friedman, HaoSheng Sun, Diane Damez-Werno, David M Dietz, Samir Zaman, Ja Wook Koo, Pamela J Kennedy, Ezekiell Mouzon, Murtaza Mogri, Rachael L Neve, Karl Deisseroth, Ming-Hu Han, Eric J Nestle. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (New York, N.Y.). vol 330. issue 6002. 2010-11-10. PMID:20947769. because loss of trkb in d2+ neurons increases their neuronal excitability, we next used optogenetic tools to control selectively the firing rate of d1+ and d2+ nucleus accumbens neurons and studied consequent effects on cocaine reward. 2010-11-10 2023-08-12 Not clear
Adam Podet, Min J Lee, Alan C Swann, Nachum Dafn. Nucleus accumbens lesions modulate the effects of methylphenidate. Brain research bulletin. vol 82. issue 5-6. 2010-11-01. PMID:20470871. in studies on cocaine and amphetamine, this effect has been reported to involve the nucleus accumbens (nac), one of the nuclei belonging to the motive circuit. 2010-11-01 2023-08-12 rat
Anthony T Fabbricatore, Udi E Ghitza, Volodymyr F Prokopenko, Mark O Wes. Electrophysiological evidence of mediolateral functional dichotomy in the rat nucleus accumbens during cocaine self-administration II: phasic firing patterns. The European journal of neuroscience. vol 31. issue 9. 2010-10-14. PMID:20525080. electrophysiological evidence of mediolateral functional dichotomy in the rat nucleus accumbens during cocaine self-administration ii: phasic firing patterns. 2010-10-14 2023-08-12 rat
Anthony T Fabbricatore, Udi E Ghitza, Volodymyr F Prokopenko, Mark O Wes. Electrophysiological evidence of mediolateral functional dichotomy in the rat nucleus accumbens during cocaine self-administration II: phasic firing patterns. The European journal of neuroscience. vol 31. issue 9. 2010-10-14. PMID:20525080. in the cocaine self-administering rat, individual nucleus accumbens (nacc) neurons exhibit phasic changes in firing rate within minutes and/or seconds of lever presses (i.e. 2010-10-14 2023-08-12 rat
Erin B Larson, Fatih Akkentli, Scott Edwards, Danielle L Graham, Diana L Simmons, Imran N Alibhai, Eric J Nestler, David W Sel. Striatal regulation of ΔFosB, FosB, and cFos during cocaine self-administration and withdrawal. Journal of neurochemistry. vol 115. issue 1. 2010-10-13. PMID:20633205. we found that cfos, fosb, and Δfosb exhibit regionally and temporally distinct expression patterns, with greater accumulation of Δfosb protein in the nucleus accumbens (nac) shell and core after chronic cocaine administration, whereas Δfosb increases in the caudate-putamen (cpu) remained similar with either acute or chronic administration. 2010-10-13 2023-08-12 rat
Xi Wang, Yi-xiao Luo, Ying-ying He, Fang-qiong Li, Hai-shui Shi, Li-fen Xue, Yan-xue Xue, Lin L. Nucleus accumbens core mammalian target of rapamycin signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 38. 2010-10-08. PMID:20861369. we found that exposure to a cocaine-related cue induced reinstatement to cocaine seeking and increased phosphorylation of p70s6 kinase (p70s6k) and ribosomal protein s6 (rps6), measures of mtor activity, in the nucleus accumbens (nac) core but not shell. 2010-10-08 2023-08-12 rat
Quincey LaPlant, Vincent Vialou, Herbert E Covington, Dani Dumitriu, Jian Feng, Brandon L Warren, Ian Maze, David M Dietz, Emily L Watts, Sergio D Iñiguez, Ja Wook Koo, Ezekiell Mouzon, William Renthal, Fiona Hollis, Hui Wang, Michele A Noonan, Yanhua Ren, Amelia J Eisch, Carlos A Bolaños, Mohamed Kabbaj, Guanghua Xiao, Rachael L Neve, Yasmin L Hurd, Ronald S Oosting, Gouping Fan, John H Morrison, Eric J Nestle. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nature neuroscience. vol 13. issue 9. 2010-10-04. PMID:20729844. we found that dnmt3a expression was regulated in mouse nucleus accumbens (nac) by chronic cocaine use and chronic social defeat stress. 2010-10-04 2023-08-12 mouse
Carrie R Ferrario, Xuan Li, Xiaoting Wang, Jeremy M Reimers, Jamie L Uejima, Marina E Wol. The role of glutamate receptor redistribution in locomotor sensitization to cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 3. 2010-09-07. PMID:19924109. alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor (ampar) surface expression in the nucleus accumbens (nac) is enhanced after withdrawal from repeated cocaine exposure. 2010-09-07 2023-08-12 rat
Annelyn Torres-Reveron, Jeremy Weedon, Diana L Dow-Edward. Methylphenidate response in prenatal cocaine-exposed rats: a behavioral and brain functional study. Brain research. vol 1337. 2010-08-25. PMID:20382132. prenatal cocaine produced insignificant effects on the rates of brain glucose metabolism overall but produced a reduced response to mpd in the nucleus accumbens in a rostral/caudal gradient compared to control. 2010-08-25 2023-08-12 rat
Lori A Knackstedt, Khaled Moussawi, Ryan Lalumiere, Marek Schwendt, Matthias Klugmann, Peter W Kaliva. Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 23. 2010-08-24. PMID:20534846. rats were either extinguished or withdrawn without extinction training (abstinence) from cocaine self-administration, and measurements of postsynaptic density proteins in the core and shell subcompartments of the nucleus accumbens were compared with yoked-saline controls. 2010-08-24 2023-08-12 rat
Mary M Torregrossa, Hayde Sanchez, Jane R Taylo. D-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 31. 2010-08-24. PMID:20685995. d-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens. 2010-08-24 2023-08-12 human
Michel M M Verheij, Eric L W de Mulder, Elvira De Leonibus, Karen M J van Loo, Alexander R Cool. Rats that differentially respond to cocaine differ in their dopaminergic storage capacity of the nucleus accumbens. Journal of neurochemistry. vol 105. issue 6. 2010-08-13. PMID:18315567. rats that differentially respond to cocaine differ in their dopaminergic storage capacity of the nucleus accumbens. 2010-08-13 2023-08-12 rat
Angelica Rocha, Peter W Kaliva. Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seeking. The European journal of neuroscience. vol 31. issue 5. 2010-07-12. PMID:20180839. although the involvement of the medial prefrontal cortex projection to the nucleus accumbens in the reinstatement of cocaine seeking has been well studied, it is not known if this projection plays a similar role in the reinstatement of cue- and methamphetamine-induced drug seeking in animals extinguished from methamphetamine self-administration. 2010-07-12 2023-08-12 rat