| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jane R Taylor, Wendy J Lynch, Hayde Sanchez, Peter Olausson, Eric J Nestler, James A Bib. Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 10. 2007-04-24. PMID:17360491. |
inhibition of cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. |
2007-04-24 |
2023-08-12 |
rat |
| Jane R Taylor, Wendy J Lynch, Hayde Sanchez, Peter Olausson, Eric J Nestler, James A Bib. Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 10. 2007-04-24. PMID:17360491. |
here we investigated the role of cdk5 activity in the nucleus accumbens (nac) on cocaine-induced locomotor sensitization, responding for reward-associated stimuli (conditioned reinforcement), and cocaine self-administration under a progressive ratio schedule. |
2007-04-24 |
2023-08-12 |
rat |
| Jonathan A Hollander, Regina M Carell. Cocaine-associated stimuli increase cocaine seeking and activate accumbens core neurons after abstinence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 13. 2007-04-24. PMID:17392469. |
electrophysiological recordings were completed in rats (n = 14) trained to self-administer cocaine to determine whether activation of nucleus accumbens (acb) neurons (core vs shell) by cocaine-associated stimuli is enhanced after 1 month of cocaine abstinence. |
2007-04-24 |
2023-08-12 |
rat |
| Jonathan A Hollander, Regina M Carell. Cocaine-associated stimuli increase cocaine seeking and activate accumbens core neurons after abstinence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 13. 2007-04-24. PMID:17392469. |
the cocaine stimulus significantly increased activation of acb core (not shell) neurons after 1 month of cocaine abstinence (compared with 1 d); this finding occurred regardless of contingency of cue presentation or cocaine availability. |
2007-04-24 |
2023-08-12 |
rat |
| Jonathan A Hollander, Regina M Carell. Cocaine-associated stimuli increase cocaine seeking and activate accumbens core neurons after abstinence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 13. 2007-04-24. PMID:17392469. |
acb core activation was not observed in other rats (n = 7) presented with the same stimulus never paired with cocaine. |
2007-04-24 |
2023-08-12 |
rat |
| Manoranjan S D'Souza, Christine L Duvauchell. Comparing nucleus accumbens and dorsal striatal dopamine responses to self-administered cocaine in naïve rats. Neuroscience letters. vol 408. issue 2. 2007-04-06. PMID:16979294. |
comparing nucleus accumbens and dorsal striatal dopamine responses to self-administered cocaine in naïve rats. |
2007-04-06 |
2023-08-12 |
rat |
| Manoranjan S D'Souza, Christine L Duvauchell. Comparing nucleus accumbens and dorsal striatal dopamine responses to self-administered cocaine in naïve rats. Neuroscience letters. vol 408. issue 2. 2007-04-06. PMID:16979294. |
dopamine (da) responses in the nucleus accumbens (nacc) and dorsal striatum (ds) are commonly associated with different aspects of cocaine effects. |
2007-04-06 |
2023-08-12 |
rat |
| Kyle J Frantz, Laura E O'Dell, Loren H Parson. Behavioral and neurochemical responses to cocaine in periadolescent and adult rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 3. 2007-04-05. PMID:16794567. |
dopamine levels in the nucleus accumbens were recorded under basal conditions (no net flux method) and after cocaine administration ( approximately 0.37, 0.74, and 2.92 mg/kg/i.v. |
2007-04-05 |
2023-08-12 |
human |
| Kyle J Frantz, Laura E O'Dell, Loren H Parson. Behavioral and neurochemical responses to cocaine in periadolescent and adult rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 3. 2007-04-05. PMID:16794567. |
no age-related difference was observed in acquisition of cocaine self-administration, or in basal or cocaine-stimulated nucleus accumbens dopamine. |
2007-04-05 |
2023-08-12 |
human |
| Kyle J Frantz, Laura E O'Dell, Loren H Parson. Behavioral and neurochemical responses to cocaine in periadolescent and adult rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 3. 2007-04-05. PMID:16794567. |
similarities in dopamine levels across age groups suggest that age-specific motor responses to cocaine are not mediated by dopamine in the nucleus accumbens. |
2007-04-05 |
2023-08-12 |
human |
| Heather C Brenhouse, Mariko L Howe, James R Stella. Differential activation of cAMP response element binding protein in discrete nucleus accumbens subregions during early and late cocaine sensitization. Behavioral neuroscience. vol 121. issue 1. 2007-04-05. PMID:17324065. |
differential activation of camp response element binding protein in discrete nucleus accumbens subregions during early and late cocaine sensitization. |
2007-04-05 |
2023-08-12 |
rat |
| Jeffery D Stekete. Cortical mechanisms of cocaine sensitization. Critical reviews in neurobiology. vol 17. issue 2. 2007-03-29. PMID:16808728. |
the present review will coalesce these studies into a working hypothesis that states that cocaine sensitization results from a decrease in inhibitory modulation of excitatory transmission from the mpfc to the vta and nucleus accumbens. |
2007-03-29 |
2023-08-12 |
Not clear |
| Marcello D'Ascenzo, Tommaso Fellin, Miho Terunuma, Raquel Revilla-Sanchez, David F Meaney, Yves P Auberson, Stephen J Moss, Philip G Haydo. mGluR5 stimulates gliotransmission in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 6. 2007-03-22. PMID:17259307. |
although metabotropic glutamate receptor 5 (mglur5) is essential for cocaine self-administration and drug-seeking behavior, there is limited knowledge of the cellular actions of this receptor in the nucleus accumbens (nac). |
2007-03-22 |
2023-08-12 |
Not clear |
| Bruce T Hope, Deepti Nagarkar, Sherry Leonard, Roy A Wis. Long-term upregulation of protein kinase A and adenylate cyclase levels in human smokers. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 8. 2007-03-22. PMID:17314292. |
repeated injections of cocaine and morphine in laboratory rats cause a variety of molecular neuroadaptations in the camp signaling pathway in nucleus accumbens and ventral tegmental area. |
2007-03-22 |
2023-08-12 |
human |
| Jeffrey W Dalley, Tim D Fryer, Laurent Brichard, Emma S J Robinson, David E H Theobald, Kristjan Lääne, Yolanda Peña, Emily R Murphy, Yasmene Shah, Katrin Probst, Irina Abakumova, Franklin I Aigbirhio, Hugh K Richards, Young Hong, Jean-Claude Baron, Barry J Everitt, Trevor W Robbin. Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science (New York, N.Y.). vol 315. issue 5816. 2007-03-14. PMID:17332411. |
nucleus accumbens d2/3 receptors predict trait impulsivity and cocaine reinforcement. |
2007-03-14 |
2023-08-12 |
rat |
| Jeffrey W Dalley, Tim D Fryer, Laurent Brichard, Emma S J Robinson, David E H Theobald, Kristjan Lääne, Yolanda Peña, Emily R Murphy, Yasmene Shah, Katrin Probst, Irina Abakumova, Franklin I Aigbirhio, Hugh K Richards, Young Hong, Jean-Claude Baron, Barry J Everitt, Trevor W Robbin. Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science (New York, N.Y.). vol 315. issue 5816. 2007-03-14. PMID:17332411. |
using positron emission tomography, we demonstrated that d2/3 receptor availability is significantly reduced in the nucleus accumbens of impulsive rats that were never exposed to cocaine and that such effects are independent of da release. |
2007-03-14 |
2023-08-12 |
rat |
| Alejandra M Pacchioni, Joseph Vallone, Roberto I Melendez, Andy Shih, Timothy H Murphy, Peter W Kaliva. Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity. Brain research. vol 1127. issue 1. 2007-03-09. PMID:17113054. |
repeated cocaine treatment in rats causes persistent neuroadaptations in glutamate neurotransmission in the nucleus accumbens that result, in part, from reduced activity of system xc-. |
2007-03-09 |
2023-08-12 |
mouse |
| Osnat Ben-Shahar, Patrick Keeley, Mariana Cook, Wayne Brake, Megan Joyce, Myriel Nyffeler, Rebecca Heston, Aaron Ettenber. Changes in levels of D1, D2, or NMDA receptors during withdrawal from brief or extended daily access to IV cocaine. Brain research. vol 1131. issue 1. 2007-03-09. PMID:17161392. |
we previously reported that brief (1 h), but not extended (6 h), daily access to cocaine results in a sensitized locomotor response to cocaine and in elevated c-fos immunoreactivity and dat binding in the nucleus accumbens (n.acc) core. |
2007-03-09 |
2023-08-12 |
human |
| N Tannu, D C Mash, S E Hemb. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Molecular psychiatry. vol 12. issue 1. 2007-02-27. PMID:17075605. |
cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. |
2007-02-27 |
2023-08-12 |
human |
| N Tannu, D C Mash, S E Hemb. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Molecular psychiatry. vol 12. issue 1. 2007-02-27. PMID:17075605. |
chronic cocaine use in humans and animal models is known to lead to pronounced alterations in neuronal function in the nucleus accumbens (nac), a brain region associated with drug reinforcement. |
2007-02-27 |
2023-08-12 |
human |