| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bruce T Hope, Deepti Nagarkar, Sherry Leonard, Roy A Wis. Long-term upregulation of protein kinase A and adenylate cyclase levels in human smokers. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 8. 2007-03-22. PMID:17314292. |
repeated injections of cocaine and morphine in laboratory rats cause a variety of molecular neuroadaptations in the camp signaling pathway in nucleus accumbens and ventral tegmental area. |
2007-03-22 |
2023-08-12 |
human |
| Jeffrey W Dalley, Tim D Fryer, Laurent Brichard, Emma S J Robinson, David E H Theobald, Kristjan Lääne, Yolanda Peña, Emily R Murphy, Yasmene Shah, Katrin Probst, Irina Abakumova, Franklin I Aigbirhio, Hugh K Richards, Young Hong, Jean-Claude Baron, Barry J Everitt, Trevor W Robbin. Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science (New York, N.Y.). vol 315. issue 5816. 2007-03-14. PMID:17332411. |
nucleus accumbens d2/3 receptors predict trait impulsivity and cocaine reinforcement. |
2007-03-14 |
2023-08-12 |
rat |
| Jeffrey W Dalley, Tim D Fryer, Laurent Brichard, Emma S J Robinson, David E H Theobald, Kristjan Lääne, Yolanda Peña, Emily R Murphy, Yasmene Shah, Katrin Probst, Irina Abakumova, Franklin I Aigbirhio, Hugh K Richards, Young Hong, Jean-Claude Baron, Barry J Everitt, Trevor W Robbin. Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science (New York, N.Y.). vol 315. issue 5816. 2007-03-14. PMID:17332411. |
using positron emission tomography, we demonstrated that d2/3 receptor availability is significantly reduced in the nucleus accumbens of impulsive rats that were never exposed to cocaine and that such effects are independent of da release. |
2007-03-14 |
2023-08-12 |
rat |
| Alejandra M Pacchioni, Joseph Vallone, Roberto I Melendez, Andy Shih, Timothy H Murphy, Peter W Kaliva. Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity. Brain research. vol 1127. issue 1. 2007-03-09. PMID:17113054. |
repeated cocaine treatment in rats causes persistent neuroadaptations in glutamate neurotransmission in the nucleus accumbens that result, in part, from reduced activity of system xc-. |
2007-03-09 |
2023-08-12 |
mouse |
| Osnat Ben-Shahar, Patrick Keeley, Mariana Cook, Wayne Brake, Megan Joyce, Myriel Nyffeler, Rebecca Heston, Aaron Ettenber. Changes in levels of D1, D2, or NMDA receptors during withdrawal from brief or extended daily access to IV cocaine. Brain research. vol 1131. issue 1. 2007-03-09. PMID:17161392. |
we previously reported that brief (1 h), but not extended (6 h), daily access to cocaine results in a sensitized locomotor response to cocaine and in elevated c-fos immunoreactivity and dat binding in the nucleus accumbens (n.acc) core. |
2007-03-09 |
2023-08-12 |
human |
| N Tannu, D C Mash, S E Hemb. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Molecular psychiatry. vol 12. issue 1. 2007-02-27. PMID:17075605. |
cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. |
2007-02-27 |
2023-08-12 |
human |
| N Tannu, D C Mash, S E Hemb. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Molecular psychiatry. vol 12. issue 1. 2007-02-27. PMID:17075605. |
chronic cocaine use in humans and animal models is known to lead to pronounced alterations in neuronal function in the nucleus accumbens (nac), a brain region associated with drug reinforcement. |
2007-02-27 |
2023-08-12 |
human |
| Enrique Rodríguez-Borrero, Alexandra Bernardo Colón, Melissa A Burgos-Mártir, José E Alvarez Carillo, Yaniré Estrada del Campo, Cynthia Abella-Ramírez, Carmen S Maldonado-Vlaa. NMDA antagonist AP-5 increase environmentally induced cocaine-conditioned locomotion within the nucleus accumbens. Pharmacology, biochemistry, and behavior. vol 85. issue 1. 2007-02-23. PMID:16963113. |
these associations can result from motor learning and reinforcing effects of cocaine, and may be mediated in part by ionotropic glutamate receptors in the nucleus accumbens (n.acc.). |
2007-02-23 |
2023-08-12 |
rat |
| Jun-ichi Izawa, Kaori Yamanashi, Taro Asakura, Yoshimi Misu, Yoshio Goshim. Differential effects of methamphetamine and cocaine on behavior and extracellular levels of dopamine and 3,4-dihydroxyphenylalanine in the nucleus accumbens of conscious rats. European journal of pharmacology. vol 549. issue 1-3. 2007-01-30. PMID:16979160. |
differential effects of methamphetamine and cocaine on behavior and extracellular levels of dopamine and 3,4-dihydroxyphenylalanine in the nucleus accumbens of conscious rats. |
2007-01-30 |
2023-08-12 |
rat |
| Gerhard Jocham, Katharina Lezoch, Christian P Müller, Emriye Kart-Teke, Joseph P Huston, M Angélica de Souza Silv. Neurokinin receptor antagonism attenuates cocaine's behavioural activating effects yet potentiates its dopamine-enhancing action in the nucleus accumbens core. The European journal of neuroscience. vol 24. issue 6. 2007-01-05. PMID:17004936. |
these data provide evidence for a contribution of nk3-rs in the acute behavioural and neurochemical effects of cocaine, involving dopaminergic activity in the core of the nucleus accumbens. |
2007-01-05 |
2023-08-12 |
rat |
| Robert E Sorge, Jane Stewar. The effects of chronic buprenorphine on intake of heroin and cocaine in rats and its effects on nucleus accumbens dopamine levels during self-administration. Psychopharmacology. vol 188. issue 1. 2006-12-22. PMID:16902770. |
the effects of chronic buprenorphine on intake of heroin and cocaine in rats and its effects on nucleus accumbens dopamine levels during self-administration. |
2006-12-22 |
2023-08-12 |
rat |
| Kimberly A Badanich, Kristopher J Adler, Cheryl L Kirstei. Adolescents differ from adults in cocaine conditioned place preference and cocaine-induced dopamine in the nucleus accumbens septi. European journal of pharmacology. vol 550. issue 1-3. 2006-12-15. PMID:17011546. |
adolescents differ from adults in cocaine conditioned place preference and cocaine-induced dopamine in the nucleus accumbens septi. |
2006-12-15 |
2023-08-12 |
rat |
| Kimberly A Badanich, Kristopher J Adler, Cheryl L Kirstei. Adolescents differ from adults in cocaine conditioned place preference and cocaine-induced dopamine in the nucleus accumbens septi. European journal of pharmacology. vol 550. issue 1-3. 2006-12-15. PMID:17011546. |
to address whether age-related differences in cocaine place preferences were related to differences in the mesolimbic dopaminergic system, we measured extracellular dopamine levels in the nucleus accumbens septi of pnd 35, pnd 45 and pnd 60 rats via quantitative microdialysis under transient conditions. |
2006-12-15 |
2023-08-12 |
rat |
| Pamela B Yang, Alan C Swann, Nachum Dafn. Chronic methylphenidate modulates locomotor activity and sensory evoked responses in the VTA and NAc of freely behaving rats. Neuropharmacology. vol 51. issue 3. 2006-12-14. PMID:16824558. |
there is some evidence that psychostimulants, such as amphetamine and cocaine, activate the ventral tegmental area (vta) and nucleus accumbens (nac). |
2006-12-14 |
2023-08-12 |
rat |
| D S Mathon, L J M J Vanderschuren, G M J Ramaker. Reduced psychostimulant effects on dopamine dynamics in the nucleus accumbens of mu-opioid receptor knockout mice. Neuroscience. vol 141. issue 4. 2006-12-04. PMID:16777349. |
our data demonstrate that in mu-opioid receptor knockout mice 1) the reuptake of dopamine in the nucleus accumbens is slower, and 2) the relative effect of cocaine and amphetamine on the reuptake of dopamine is smaller compared with wild type mice. |
2006-12-04 |
2023-08-12 |
mouse |
| Dawn N Albertson, Carl J Schmidt, Gregory Kapatos, Michael J Banno. Distinctive profiles of gene expression in the human nucleus accumbens associated with cocaine and heroin abuse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16710320. |
distinctive profiles of gene expression in the human nucleus accumbens associated with cocaine and heroin abuse. |
2006-11-01 |
2023-08-12 |
human |
| Dawn N Albertson, Carl J Schmidt, Gregory Kapatos, Michael J Banno. Distinctive profiles of gene expression in the human nucleus accumbens associated with cocaine and heroin abuse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16710320. |
these data suggest that the profiles of nucleus accumbens gene expression associated with chronic heroin or cocaine abuse are largely unique, despite what are thought to be common effects of these drugs on dopamine neurotransmission in this brain region. |
2006-11-01 |
2023-08-12 |
human |
| Bruce T Hope, Danielle E Simmons, Tim B Mitchell, Justin D Kreuter, Brandi J Mattso. Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage. The European journal of neuroscience. vol 24. issue 3. 2006-11-01. PMID:16930414. |
cocaine-induced locomotor activity and fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage. |
2006-11-01 |
2023-08-12 |
rat |
| Bruce T Hope, Danielle E Simmons, Tim B Mitchell, Justin D Kreuter, Brandi J Mattso. Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage. The European journal of neuroscience. vol 24. issue 3. 2006-11-01. PMID:16930414. |
in contrast, cocaine-induced fos expression was absent altogether in nucleus accumbens and unaltered in caudate-putamen 1 month after repeated cocaine administration in the home cage. |
2006-11-01 |
2023-08-12 |
rat |
| Bruce T Hope, Danielle E Simmons, Tim B Mitchell, Justin D Kreuter, Brandi J Mattso. Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage. The European journal of neuroscience. vol 24. issue 3. 2006-11-01. PMID:16930414. |
as cocaine-induced locomotor activity was also enhanced 1 and 6 months after repeated cocaine administration in locomotor activity chambers, we wanted to confirm that neuronal activity in nucleus accumbens mediates cocaine-induced locomotor activity using our particular treatment regimen. |
2006-11-01 |
2023-08-12 |
rat |