| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter A Neumann, Yicun Wang, Yijin Yan, Yao Wang, Masago Ishikawa, Ranji Cui, Yanhua H Huang, Susan R Sesack, Oliver M Schlüter, Yan Don. Cocaine-Induced Synaptic Alterations in Thalamus to Nucleus Accumbens Projection. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:27074816. |
exposure to cocaine induces addiction-associated behaviors partially through remodeling neurocircuits in the nucleus accumbens (nac). |
2018-01-09 |
2023-08-13 |
rat |
| Yan Don. Silent Synapse-Based Circuitry Remodeling in Drug Addiction. The international journal of neuropsychopharmacology. vol 19. issue 5. 2018-01-08. PMID:26721952. |
exposure to cocaine, and likely other drugs of abuse, generates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-silent glutamatergic synapses in the nucleus accumbens. |
2018-01-08 |
2023-08-13 |
Not clear |
| Bok Soon Go, Sarah M Barry, Jacqueline F McGint. Glutamatergic neurotransmission in the prefrontal cortex mediates the suppressive effect of intra-prelimbic cortical infusion of BDNF on cocaine-seeking. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 12. 2018-01-05. PMID:27765467. |
cocaine self-administration disturbs glutamatergic transmission in the nucleus accumbens that is prevented by infusion of brain-derived neurotrophic factor (bdnf) into the prelimbic area of the prefrontal cortex. |
2018-01-05 |
2023-08-13 |
rat |
| Francesco Congestri, Francesca Formenti, Viviana Sonntag, Gael Hdou, Francesco Cresp. Selective D3 Receptor Antagonist SB-277011-A Potentiates the Effect of Cocaine on Extracellular Dopamine in the Nucleus Accumbens: a Dual Core-Shell Voltammetry Study in Anesthetized Rats. Sensors (Basel, Switzerland). vol 8. issue 11. 2018-01-04. PMID:27873908. |
selective d3 receptor antagonist sb-277011-a potentiates the effect of cocaine on extracellular dopamine in the nucleus accumbens: a dual core-shell voltammetry study in anesthetized rats. |
2018-01-04 |
2023-08-13 |
rat |
| Jean Terrier, Christian Lüscher, Vincent Pascol. Cell-Type Specific Insertion of GluA2-Lacking AMPARs with Cocaine Exposure Leading to Sensitization, Cue-Induced Seeking, and Incubation of Craving. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 7. 2018-01-02. PMID:26585289. |
here we exposed mice to various regimens of cocaine and recorded excitatory transmission onto identified medium-sized spiny neurons (msn, expressing fluorescent proteins under the control of either d1r or d2r dopamine receptor promotor) in the nucleus accumbens at time points when behavioral adaptations are observed. |
2018-01-02 |
2023-08-13 |
mouse |
| Daniel J Tobiansky, Ryan G Will, Kevin D Lominac, Jonathan M Turner, Tomoko Hattori, Krittika Krishnan, Julia R Martz, Victoria L Nutsch, Juan M Domingue. Estradiol in the Preoptic Area Regulates the Dopaminergic Response to Cocaine in the Nucleus Accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 7. 2018-01-02. PMID:26647972. |
estradiol in the preoptic area regulates the dopaminergic response to cocaine in the nucleus accumbens. |
2018-01-02 |
2023-08-13 |
Not clear |
| Eric J Vallender, Dharmendra B Goswami, Nina M Shinday, Susan V Westmoreland, Wei-Dong Yao, James K Rowlet. Transcriptomic profiling of the ventral tegmental area and nucleus accumbens in rhesus macaques following long-term cocaine self-administration. Drug and alcohol dependence. vol 175. 2017-12-18. PMID:28376414. |
transcriptomic profiling of the ventral tegmental area and nucleus accumbens in rhesus macaques following long-term cocaine self-administration. |
2017-12-18 |
2023-08-13 |
Not clear |
| L Recinella, S Leone, C Ferrante, A Chiavaroli, C Di Nisio, S Martinotti, M Vacca, L Brunetti, G Orland. Effects of central fibroblast growth factor 21 (FGF21) in energy balance. Journal of biological regulators and homeostatic agents. vol 31. issue 3. 2017-12-14. PMID:28889722. |
in addition, we evaluated the effects of fgf21 on orexigenic [agouti-related peptide (agrp) and neuropeptide y (npy)] and anorexigenic [cocaine and amphetamine-regulated transcript (cart) and proopiomelanocortin (pomc)] peptides, in the hypothalamus, and dopamine (da) and serotonin (5-hydroxytriptamine, 5-ht) levels in nucleus accumbens (nac). |
2017-12-14 |
2023-08-13 |
rat |
| Bryan F Singer, Myranda A Bryan, Pavlo Popov, Terry E Robinson, Brandon J Aragon. Rapid induction of dopamine sensitization in the nucleus accumbens shell induced by a single injection of cocaine. Behavioural brain research. vol 324. 2017-12-13. PMID:28223145. |
repeated intermittent exposure to cocaine results in the neurochemical sensitization of dopamine (da) transmission within the nucleus accumbens (nac). |
2017-12-13 |
2023-08-13 |
rat |
| Caroline Jung, Ariana Rabinowitsch, Wei Ting Lee, Danielle Zheng, Soledad Cabeza de Vaca, Kenneth D Car. Effects of food restriction on expression of place conditioning and biochemical correlates in rat nucleus accumbens. Psychopharmacology. vol 233. issue 17. 2017-12-12. PMID:27376947. |
when ad libitum-fed rats undergo cocaine place preference conditioning (cpp) but are switched to food restriction for testing, cpp becomes resistant to extinction and correlates with phosphorylation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor glua1 at ser845 in nucleus accumbens (nac) core. |
2017-12-12 |
2023-08-13 |
rat |
| M Shen, C Jiang, P Liu, F Wang, L M. Mesolimbic leptin signaling negatively regulates cocaine-conditioned reward. Translational psychiatry. vol 6. issue 12. 2017-12-07. PMID:27922639. |
our results showed that inhibition of leptin signaling by intracerebroventricular infusion of the leptin receptor (lepr) antagonist smla during cocaine conditioning increased the cocaine-cpp and upregulated the level of dopamine and its metabolites in the nucleus accumbens (nac). |
2017-12-07 |
2023-08-13 |
Not clear |
| Courtney M Keller, Kelly N Breaux, Nicholas E Goeder. Effects of the combination of metyrapone and oxazepam on cocaine-induced increases in corticosterone in the medial prefrontal cortex and nucleus accumbens. Psychoneuroendocrinology. vol 77. 2017-12-07. PMID:28024272. |
the administration of cocaine resulted in an increase in corticosterone in the medial prefrontal cortex following vehicle pretreatment, which was not observed in the nucleus accumbens. |
2017-12-07 |
2023-08-13 |
rat |
| Stephanie K Nygard, Anthony Klambatsen, Bailey Balouch, Vanya Quinones-Jenab, Shirzad Jena. NMDAR dependent intracellular responses associated with cocaine conditioned place preference behavior. Behavioural brain research. vol 317. 2017-11-29. PMID:27664298. |
n-methyl-d-aspartate receptor (nmdar) antagonism prior to cocaine administration during conditioning blocked the acquisition of cocaine cpp and reduced nucleus accumbens (nac) phosphorylated-erk (perk) and phosphorylated creb (pcreb) levels following the cpp test (drug-free). |
2017-11-29 |
2023-08-13 |
Not clear |
| Caitlin A Orsini, Marci R Mitchell, Sara C Heshmati, Kristy G Shimp, Megan S Spurrell, Jennifer L Bizon, Barry Setlo. Effects of nucleus accumbens amphetamine administration on performance in a delay discounting task. Behavioural brain research. vol 321. 2017-11-29. PMID:28057530. |
chronic cocaine can also result in enhanced dopamine (da) release in the nucleus accumbens (nac) in response to reward-related cues. |
2017-11-29 |
2023-08-13 |
rat |
| Wen-Yu Tzeng, Chian-Fang G Cherng, Shyi-Wu Wang, Lung Y. Familiar companions diminish cocaine conditioning and attenuate cocaine-stimulated dopamine release in the nucleus accumbens. Behavioural brain research. vol 306. 2017-11-17. PMID:27001454. |
familiar companions diminish cocaine conditioning and attenuate cocaine-stimulated dopamine release in the nucleus accumbens. |
2017-11-17 |
2023-08-13 |
mouse |
| Wen-Yu Tzeng, Chian-Fang G Cherng, Shyi-Wu Wang, Lung Y. Familiar companions diminish cocaine conditioning and attenuate cocaine-stimulated dopamine release in the nucleus accumbens. Behavioural brain research. vol 306. 2017-11-17. PMID:27001454. |
at 20mg/kg, cocaine stimulated dopamine (da) release in the nucleus accumbens as evidenced by a significant decrease in total (spontaneous and electrical stimulation-provoked) da release in accumbal superfusate samples. |
2017-11-17 |
2023-08-13 |
mouse |
| Wen-Yu Tzeng, Chian-Fang G Cherng, Shyi-Wu Wang, Lung Y. Familiar companions diminish cocaine conditioning and attenuate cocaine-stimulated dopamine release in the nucleus accumbens. Behavioural brain research. vol 306. 2017-11-17. PMID:27001454. |
taken together, these results indicate that familiar companions, regardless of their pharmacological status, may exert dampening effects on cpp induced by moderate to high conditioning doses of cocaine, at least in part, by preventing cocaine-stimulated da release in the nucleus accumbens. |
2017-11-17 |
2023-08-13 |
mouse |
| Eduardo A V Marinho, Alexandre J Oliveira-Lima, Thais S Yokoyama, Renan Santos-Baldaia, Luciana T C Ribeiro, Marilia A Baldaia, Raphael Wuo da Silva, Andre Willian Hollais, Fernanda Talhati, Beatriz Monteiro Longo, Lais Fernanda Berro, Roberto Frussa-Filh. Post-sensitization treatment with rimonabant blocks the expression of cocaine-induced behavioral sensitization and c-Fos protein in mice. Pharmacology, biochemistry, and behavior. vol 156. 2017-11-09. PMID:28366798. |
c-fos protein expression was evaluated in the nucleus accumbens (nacc), ventral tegmental area (vta), basolateral amygdala (bla), medial prefrontal cortex (mpfc) and caudate-putamen (cpu) after the last (cocaine) challenge. |
2017-11-09 |
2023-08-13 |
mouse |
| Yafang Zhang, Elizabeth J Crofton, Xiuzhen Fan, Dingge Li, Fanping Kong, Mala Sinha, Bruce A Luxon, Heidi M Spratt, Cheryl F Lichti, Thomas A Gree. Convergent transcriptomics and proteomics of environmental enrichment and cocaine identifies novel therapeutic strategies for addiction. Neuroscience. vol 339. 2017-11-06. PMID:27717806. |
the current study is a secondary analysis of the convergence of recently published separate transcriptomic and proteomic analyses of nucleus accumbens (nac) tissue from rats subjected to environmental enrichment vs. isolation and cocaine self-administration vs. saline. |
2017-11-06 |
2023-08-13 |
rat |
| Michael P Saddori. Terminal Dopamine Release Kinetics in the Accumbens Core and Shell Are Distinctly Altered after Withdrawal from Cocaine Self-Administration. eNeuro. vol 3. issue 5. 2017-10-31. PMID:27752541. |
repeated self-administration of cocaine is associated with impairments in motivated behaviors as well as alterations in both dopamine (da) release and neural signaling within the nucleus accumbens (nac). |
2017-10-31 |
2023-08-13 |
rat |