| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Frankie R Gonzales, Kristin K Howell, Lara E Dozier, Stephan G Anagnostaras, Gentry N Patric. Proteasome phosphorylation regulates cocaine-induced sensitization. Molecular and cellular neurosciences. vol 88. 2019-01-31. PMID:29217409. |
repeated exposure to cocaine produces structural and functional modifications at synapses from neurons in several brain regions including the nucleus accumbens. |
2019-01-31 |
2023-08-13 |
Not clear |
| Katsuyuki Kaned. The contribution of neuroplasticity induced in cholinergic neurons of the laterodorsal tegmental nucleus to cocaine addiction. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 37. issue 1. 2019-01-28. PMID:30452815. |
cocaine-induced neuroplasticity in brain reward circuitry consisting of the ventral tegmental area (vta), nucleus accumbens and medial pre- frontal cortex is critical for developing cocaine addiction. |
2019-01-28 |
2023-08-13 |
rat |
| Katherine N Wright, Amanda M Dossat, Caroline E Strong, Lindsay L Sailer, Samantha M Pavlock, Mohamed Kabba. Optogenetic inhibition of medial prefrontal cortex projections to the nucleus accumbens core and methyl supplementation via L-Methionine attenuates cocaine-primed reinstatement. Integrative zoology. vol 13. issue 6. 2019-01-18. PMID:30318755. |
indeed, the medial prefrontal cortex (mpfc) projections to the nucleus accumbens (nac) are critically important for reinstated cocaine-seeking in a rodent model of cocaine relapse. |
2019-01-18 |
2023-08-13 |
rat |
| Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestle. Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine. Nature communications. vol 9. issue 1. 2018-12-12. PMID:30089879. |
transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine. |
2018-12-12 |
2023-08-13 |
Not clear |
| Rachel-Karson Thériault, Francesco Leri, Bettina Kalisc. The role of neuronal nitric oxide synthase in cocaine place preference and mu opioid receptor expression in the nucleus accumbens. Psychopharmacology. vol 235. issue 9. 2018-12-11. PMID:29992335. |
the role of neuronal nitric oxide synthase in cocaine place preference and mu opioid receptor expression in the nucleus accumbens. |
2018-12-11 |
2023-08-13 |
Not clear |
| Rachel-Karson Thériault, Francesco Leri, Bettina Kalisc. The role of neuronal nitric oxide synthase in cocaine place preference and mu opioid receptor expression in the nucleus accumbens. Psychopharmacology. vol 235. issue 9. 2018-12-11. PMID:29992335. |
there is evidence that central mu opioid receptors (mors) are implicated in several aspects of cocaine addiction, and that mor expression is elevated by cocaine in vitro and in the nucleus accumbens (nac) when administered in vivo. |
2018-12-11 |
2023-08-13 |
Not clear |
| Anna E Ingebretson, Matthew C Hearing, Ethan D Huffington, Mark J Thoma. Endogenous dopamine and endocannabinoid signaling mediate cocaine-induced reversal of AMPAR synaptic potentiation in the nucleus accumbens shell. Neuropharmacology. vol 131. 2018-11-13. PMID:29225042. |
during a 10-14 day period of abstinence from cocaine, ampar signaling is potentiated at synapses on nucleus accumbens (nac) medium spiny neurons (msns), promoting a state of heightened synaptic excitability. |
2018-11-13 |
2023-08-13 |
Not clear |
| Zi-Jun Wang, Jennifer A Martin, Amy M Gancarz, Danielle N Adank, Fraser J Sim, David M Diet. Activin A is increased in the nucleus accumbens following a cocaine binge. Scientific reports. vol 7. 2018-11-08. PMID:28272550. |
activin a is increased in the nucleus accumbens following a cocaine binge. |
2018-11-08 |
2023-08-13 |
Not clear |
| M C Arenas, C I Navarro-Francés, S Montagud-Romero, J Miñarro, C Manzaned. Baseline prepulse inhibition of the startle reflex predicts the sensitivity to the conditioned rewarding effects of cocaine in male and female mice. Psychopharmacology. vol 235. issue 9. 2018-11-06. PMID:29955900. |
the dopamine baseline in the nucleus accumbens plays a key role in ppi regulation as well as in the rewarding effects of cocaine. |
2018-11-06 |
2023-08-13 |
mouse |
| Tong Zhang, Satoshi Deyama, Masaki Domoto, Shintaro Wada, Junko Yanagida, Hitoki Sasase, Eiichi Hinoi, Naoya Nishitani, Kazuki Nagayasu, Shuji Kaneko, Katsuyuki Kaned. Activation of GABAergic Neurons in the Nucleus Accumbens Mediates the Expression of Cocaine-Associated Memory. Biological & pharmaceutical bulletin. vol 41. issue 7. 2018-10-24. PMID:29962403. |
here, we investigated the possible contribution of γ-aminobutyrate (gaba)ergic neurons in the nucleus accumbens (nac), a key brain region associated with the rewarding and reinforcing effects of cocaine, to the expression of cocaine-associated memory using the conditioned place preference (cpp) paradigm combined with designer receptors exclusively activated by designer drugs (dreadd) technology. |
2018-10-24 |
2023-08-13 |
mouse |
| Xue-Jiao Gao, Kai Yuan, Lu Cao, Wei Yan, Yi-Xiao Luo, Min Jian, Jian-Feng Liu, Qin Fang, Ji-Shi Wang, Ying Han, Jie Shi, Lin L. AMPK signaling in the nucleus accumbens core mediates cue-induced reinstatement of cocaine seeking. Scientific reports. vol 7. issue 1. 2018-09-18. PMID:28432301. |
here, we investigated the role of ampk activity in the nucleus accumbens (nac) in relapse to cocaine seeking. |
2018-09-18 |
2023-08-13 |
Not clear |
| Yiyun Lin, Hui Gu, Linhong Jiang, Wei Xu, Chunqi Liu, Yan Li, Xinying Qian, Dandan Li, Zhuoling Li, Jing Hu, Huaqin Zhang, Wei Guo, Yinglan Zhao, Xiaobo Ce. Cocaine modifies brain lipidome in mice. Molecular and cellular neurosciences. vol 85. 2018-07-25. PMID:28830718. |
in this study, we used a lc-ms-based lipidomic approach to investigate the impact of cocaine on brain lipidome in two mouse models, cocaine-conditioned place preference (cpp) and hyperlocomotor models and the lipidome was profoundly modified in the nucleus accumbens (nac) and striatum respectively. |
2018-07-25 |
2023-08-13 |
mouse |
| Gregory C Sartor, Samuel K Powell, Dmitry Velmeshev, David Y Lin, Marco Magistri, Hannah J Wiedner, Andrea M Malvezzi, Nadja S Andrade, Mohammad A Faghihi, Claes Wahlested. Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens. Molecular and cellular neurosciences. vol 85. 2018-07-25. PMID:29055697. |
cocaine alters homer1 natural antisense transcript in the nucleus accumbens. |
2018-07-25 |
2023-08-13 |
mouse |
| Gregory C Sartor, Samuel K Powell, Dmitry Velmeshev, David Y Lin, Marco Magistri, Hannah J Wiedner, Andrea M Malvezzi, Nadja S Andrade, Mohammad A Faghihi, Claes Wahlested. Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens. Molecular and cellular neurosciences. vol 85. 2018-07-25. PMID:29055697. |
we found that 22% of the genes examined contain nats and that expression of homer1 natural antisense transcript (homer1-as) was altered in the nucleus accumbens (nac) of mice 2h and 10days following repeated cocaine administration. |
2018-07-25 |
2023-08-13 |
mouse |
| Tatiana A Shnitko, Kyla D Mace, Kaitlin M Sullivan, W Kyle Martin, Elizabeth H Andersen, Sarah K Williams Avram, Josephine M Johns, Donita L Robinso. Use of fast-scan cyclic voltammetry to assess phasic dopamine release in rat models of early postpartum maternal behavior and neglect. Behavioural pharmacology. vol 28. issue 8. 2018-07-20. PMID:29068793. |
thus, we used fast-scan cyclic voltammetry to measure individual dopamine transients in the nucleus accumbens of early postpartum rats and compared them with dopamine transients in virgins and in postpartum females exposed to cocaine during pregnancy, which is known to disrupt mb. |
2018-07-20 |
2023-08-13 |
rat |
| Jun Yu, Yijin Yan, King-Lun Li, Yao Wang, Yanhua H Huang, Nathaniel N Urban, Eric J Nestler, Oliver M Schlüter, Yan Don. Nucleus accumbens feedforward inhibition circuit promotes cocaine self-administration. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 41. 2018-06-26. PMID:28973852. |
nucleus accumbens feedforward inhibition circuit promotes cocaine self-administration. |
2018-06-26 |
2023-08-13 |
Not clear |
| Daniel S Wheeler, Amanda L Ebben, Beliz Kurtoglu, Marissa E Lovell, Austin T Bohn, Isabella A Jasek, David A Baker, John R Mantsch, Paul J Gasser, Robert A Wheele. Corticosterone regulates both naturally occurring and cocaine-induced dopamine signaling by selectively decreasing dopamine uptake. The European journal of neuroscience. vol 46. issue 10. 2018-06-22. PMID:28965353. |
this effect is also observed when the stress hormone corticosterone is administered directly into the nucleus accumbens (nac), indicating that glucocorticoids act locally in dopamine terminal regions to enhance cocaine's effects on dopamine signaling. |
2018-06-22 |
2023-08-13 |
rat |
| Marc Dos Santos, Marine Salery, Benoit Forget, Maria Alexandra Garcia Perez, Sandrine Betuing, Thomas Boudier, Peter Vanhoutte, Jocelyne Caboche, Nicolas Hec. Rapid Synaptogenesis in the Nucleus Accumbens Is Induced by a Single Cocaine Administration and Stabilized by Mitogen-Activated Protein Kinase Interacting Kinase-1 Activity. Biological psychiatry. vol 82. issue 11. 2018-06-21. PMID:28545678. |
rapid synaptogenesis in the nucleus accumbens is induced by a single cocaine administration and stabilized by mitogen-activated protein kinase interacting kinase-1 activity. |
2018-06-21 |
2023-08-13 |
Not clear |
| Marc Dos Santos, Marine Salery, Benoit Forget, Maria Alexandra Garcia Perez, Sandrine Betuing, Thomas Boudier, Peter Vanhoutte, Jocelyne Caboche, Nicolas Hec. Rapid Synaptogenesis in the Nucleus Accumbens Is Induced by a Single Cocaine Administration and Stabilized by Mitogen-Activated Protein Kinase Interacting Kinase-1 Activity. Biological psychiatry. vol 82. issue 11. 2018-06-21. PMID:28545678. |
repeated cocaine exposure produces new spine formation in striatal projection neurons (spns) of the nucleus accumbens. |
2018-06-21 |
2023-08-13 |
Not clear |
| Eun Young Jang, Chae Ha Yang, David M Hedges, Soo Phil Kim, Jun Yeon Lee, Tyler G Ekins, Brandon T Garcia, Hee Young Kim, Ashley C Nelson, Nam Jun Kim, Scott C Steffense. The role of reactive oxygen species in methamphetamine self-administration and dopamine release in the nucleus accumbens. Addiction biology. vol 22. issue 5. 2018-05-16. PMID:27417190. |
we have recently reported that ros are implicated in behavior changes and da release in the nucleus accumbens (nac) following cocaine administration. |
2018-05-16 |
2023-08-13 |
rat |