Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Francesca Felicia Caputi, Lucia Caffino, Sanzio Candeletti, Fabio Fumagalli, Patrizia Romuald. Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens. Drug and alcohol dependence. vol 197. 2019-07-01. PMID:30818133. |
short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mrna levels and bdnf signaling in the rat nucleus accumbens. |
2019-07-01 |
2023-08-13 |
rat |
Matthew Hearin. Prefrontal-accumbens opioid plasticity: Implications for relapse and dependence. Pharmacological research. vol 139. 2019-05-13. PMID:30465850. |
these processes are not mutually exclusive and reflect drug-induced modifications within prefrontal cortical and nucleus accumbens circuits, however unlike psychostimulants such as cocaine, far less is known about the temporal, anatomical, and cellular dynamics of these changes. |
2019-05-13 |
2023-08-13 |
Not clear |
India A Reddy, Nicholas K Smith, Kevin Erreger, Dipanwita Ghose, Christine Saunders, Daniel J Foster, Brandon Turner, Amanda Poe, Vance L Albaugh, Owen McGuinness, Troy A Hackett, Brad A Grueter, Naji N Abumrad, Charles Robb Flynn, Aurelio Gall. Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward. PLoS biology. vol 16. issue 7. 2019-05-06. PMID:30048457. |
viral restoration of tgr5 in the nucleus accumbens of tgr5 knockout animals is sufficient to restore cocaine reward, centrally localizing this tgr5-mediated modulation. |
2019-05-06 |
2023-08-13 |
mouse |
Judit Cabana-Domínguez, Carlos Roncero, Laura Pineda-Cirera, R Felipe Palma-Álvarez, Elena Ros-Cucurull, Lara Grau-López, Abderaman Esojo, Miquel Casas, Concepció Arenas, Josep Antoni Ramos-Quiroga, Marta Ribasés, Noèlia Fernàndez-Castillo, Bru Corman. Association of the PLCB1 gene with drug dependence. Scientific reports. vol 7. issue 1. 2019-05-01. PMID:28860459. |
finally, we explored the possibility that plcb1 expression is altered by cocaine and we observed a significant upregulation of the gene in the nucleus accumbens of cocaine abusers and in human dopaminergic-like neurons after cocaine treatment. |
2019-05-01 |
2023-08-13 |
human |
Rosalba Satta, Briana Certa, Donghong He, Amy W Lase. Estrogen Receptor β in the Nucleus Accumbens Regulates the Rewarding Properties of Cocaine in Female Mice. The international journal of neuropsychopharmacology. vol 21. issue 4. 2019-04-29. PMID:29294029. |
estrogen receptor β in the nucleus accumbens regulates the rewarding properties of cocaine in female mice. |
2019-04-29 |
2023-08-13 |
mouse |
Ruiming Zhu, Qian Bu, Dengqi Fu, Xue Shao, Linhong Jiang, Wei Guo, Bo Chen, Bin Liu, Zhengtao Hu, Jingwei Tian, Yinglan Zhao, Xiaobo Ce. Toll-like receptor 3 modulates the behavioral effects of cocaine in mice. Journal of neuroinflammation. vol 15. issue 1. 2019-04-08. PMID:29571298. |
the nucleus accumbens in the midbrain dopamine limbic system plays a key role in cocaine addiction. |
2019-04-08 |
2023-08-13 |
mouse |
Mary M Torregrossa, Matthew MacDonald, Kathryn L Stone, TuKiet T Lam, Angus C Nairn, Jane R Taylo. Phosphoproteomic analysis of cocaine memory extinction and reconsolidation in the nucleus accumbens. Psychopharmacology. vol 236. issue 1. 2019-04-08. PMID:30411139. |
phosphoproteomic analysis of cocaine memory extinction and reconsolidation in the nucleus accumbens. |
2019-04-08 |
2023-08-13 |
Not clear |
Jinxu Liu, Pauravi J Gandhi, Ratnamala Pavuluri, Gajanan P Shelkar, Shashank M Dravi. Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens. Translational psychiatry. vol 8. issue 1. 2019-04-01. PMID:30315226. |
cocaine exposure induces plasticity of glutamatergic synapses of medium spiny neurons (msns) in the nucleus accumbens (nac), which has been proposed to contribute to its addictive behavior. |
2019-04-01 |
2023-08-13 |
mouse |
Beata Bystrowska, Małgorzata Frankowska, Irena Smaga, Lucyna Pomierny-Chamioło, Małgorzata Fili. Effects of Cocaine Self-Administration and Its Extinction on the Rat Brain Cannabinoid CB1 and CB2 Receptors. Neurotoxicity research. vol 34. issue 3. 2019-03-14. PMID:29754307. |
following cocaine abstinence after 10 days of extinction training, we detected increases in the expression of cb1 receptors in the substantia nigra in both cocaine groups and in the subregions of the amygdala for only the yoked cocaine controls, while any method of cocaine exposure resulted in a decrease in cb2 receptor expression in the prefrontal cortex (p < 0.01), nucleus accumbens (p < 0.01), and medial globus pallidus (p < 0.01). |
2019-03-14 |
2023-08-13 |
rat |
Anna G McGrath, Jeffrey D Lenz, Lisa A Brian. PKMζ in the nucleus accumbens acts to dampen cocaine seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 12. 2019-03-11. PMID:30111812. |
pkmζ in the nucleus accumbens acts to dampen cocaine seeking. |
2019-03-11 |
2023-08-13 |
mouse |
Anna G McGrath, Jeffrey D Lenz, Lisa A Brian. PKMζ in the nucleus accumbens acts to dampen cocaine seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 12. 2019-03-11. PMID:30111812. |
conditional deletion of pkmζ within the nucleus accumbens recapitulated the increase in cocaine taking and seeking seen in the constitutive knockout mice, but only in male animals. |
2019-03-11 |
2023-08-13 |
mouse |
Anna G McGrath, Jeffrey D Lenz, Lisa A Brian. PKMζ in the nucleus accumbens acts to dampen cocaine seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 12. 2019-03-11. PMID:30111812. |
site-specific knockdown of pkmζ in the nucleus accumbens had no effect on cocaine taking or seeking in female mice. |
2019-03-11 |
2023-08-13 |
mouse |
Ethan M Anderson, Erin B Larson, Daniel Guzman, Anne Marie Wissman, Rachael L Neve, Eric J Nestler, David W Sel. Overexpression of the Histone Dimethyltransferase G9a in Nucleus Accumbens Shell Increases Cocaine Self-Administration, Stress-Induced Reinstatement, and Anxiety. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 4. 2019-03-07. PMID:29217682. |
one epigenetic alteration involves reductions in levels of the histone dimethyltransferase g9a in nucleus accumbens (nac) after chronic cocaine administration. |
2019-03-07 |
2023-08-13 |
rat |
Marc Dos Santos, Emma N Cahill, Gregory Dal Bo, Peter Vanhoutte, Jocelyne Caboche, Bruno Giros, Nicolas Hec. Cocaine increases dopaminergic connectivity in the nucleus accumbens. Brain structure & function. vol 223. issue 2. 2019-02-25. PMID:29027032. |
cocaine increases dopaminergic connectivity in the nucleus accumbens. |
2019-02-25 |
2023-08-13 |
mouse |
R Chen, S McIntosh, S E Hemby, H Sun, T Sexton, T J Martin, S R Childer. High and low doses of cocaine intake are differentially regulated by dopamine D2 receptors in the ventral tegmental area and the nucleus accumbens. Neuroscience letters. vol 671. 2019-02-18. PMID:29454035. |
high and low doses of cocaine intake are differentially regulated by dopamine d2 receptors in the ventral tegmental area and the nucleus accumbens. |
2019-02-18 |
2023-08-13 |
rat |
R M Bastle, R J Oliver, A S Gardiner, N S Pentkowski, F Bolognani, A M Allan, T Chaudhury, M St Peter, N Galles, C Smith, J L Neisewander, N I Perrone-Bizzozer. In silico identification and in vivo validation of miR-495 as a novel regulator of motivation for cocaine that targets multiple addiction-related networks in the nucleus accumbens. Molecular psychiatry. vol 23. issue 2. 2019-02-15. PMID:28044061. |
in silico identification and in vivo validation of mir-495 as a novel regulator of motivation for cocaine that targets multiple addiction-related networks in the nucleus accumbens. |
2019-02-15 |
2023-08-13 |
mouse |
Amy R Johnson, Matthew L Banks, Dana E Selley, S Stevens Negu. Amphetamine maintenance differentially modulates effects of cocaine, methylenedioxypyrovalerone (MDPV), and methamphetamine on intracranial self-stimulation and nucleus accumbens dopamine in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 8. 2019-02-14. PMID:29703999. |
amphetamine maintenance differentially modulates effects of cocaine, methylenedioxypyrovalerone (mdpv), and methamphetamine on intracranial self-stimulation and nucleus accumbens dopamine in rats. |
2019-02-14 |
2023-08-13 |
rat |
Jung Won Lee, Wha Young Kim, Jeong-Hoon Ki. Leptin in the nucleus accumbens blocks the increase of GluA1 phosphorylation induced by acute cocaine administration. Neuroreport. vol 29. issue 6. 2019-02-07. PMID:29521680. |
leptin in the nucleus accumbens blocks the increase of glua1 phosphorylation induced by acute cocaine administration. |
2019-02-07 |
2023-08-13 |
rat |
Jung Won Lee, Wha Young Kim, Jeong-Hoon Ki. Leptin in the nucleus accumbens blocks the increase of GluA1 phosphorylation induced by acute cocaine administration. Neuroreport. vol 29. issue 6. 2019-02-07. PMID:29521680. |
leptin in the rat's nucleus accumbens (nacc) core has previously shown to disrupt the effects of acute administration of cocaine on both locomotor activity and the phosphorylation levels of glycogen synthase kinase 3β. |
2019-02-07 |
2023-08-13 |
rat |
Karine Guillem, Serge H Ahme. Incubation of Accumbal Neuronal Reactivity to Cocaine Cues During Abstinence Predicts Individual Vulnerability to Relapse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 5. 2019-02-06. PMID:28920590. |
we recorded nucleus accumbens (nac) neuronal responses to drug conditioned stimuli (cs) 1 day before and after 1 month of abstinence from cocaine intake escalation. |
2019-02-06 |
2023-08-13 |
rat |