| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cody A Siciliano, Sara R Jone. Cocaine Potency at the Dopamine Transporter Tracks Discrete Motivational States During Cocaine Self-Administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 9. 2018-05-09. PMID:28139678. |
here we combined a behavioral economics approach with cocaine self-administration and ex vivo voltammetric recording of dopamine signaling in the core of the nucleus accumbens of rats to determine the relationship between dopamine signaling and discrete aspects of cocaine taking and seeking. |
2018-05-09 |
2023-08-13 |
rat |
| Sabyasachi Dash, Muthukumar Balasubramaniam, Tanu Rana, Arthur Godino, Emily G Peck, Jeffery Shawn Goodwin, Fernando Villalta, Erin S Calipari, Eric J Nestler, Chandravanu Dash, Jui Pandhar. Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b. eNeuro. vol 4. issue 4. 2018-05-03. PMID:28828398. |
acute and chronic cocaine exposure resulted in the downregulation of mir-125b concurrent with upregulation of parp-1 in dopaminergic neuronal cells and nucleus accumbens (nac) of mice but not in the medial prefrontal cortex (pfc) or ventral tegmental area (vta). |
2018-05-03 |
2023-08-13 |
mouse |
| Alaa M Hammad, Yusuf S Althobaiti, Sujan C Das, Youssef Sar. Effects of repeated cocaine exposure and withdrawal on voluntary ethanol drinking, and the expression of glial glutamate transporters in mesocorticolimbic system of P rats. Molecular and cellular neurosciences. vol 82. 2018-04-24. PMID:28442364. |
cocaine exposure has been shown to induce a dysregulation in glutamate homeostasis and a decrease in the expression of glt-1 and xct in the nucleus accumbens (nac). |
2018-04-24 |
2023-08-13 |
rat |
| Ilaria Ceglia, Ko-Woon Lee, Michael E Cahill, Steven M Graves, David Dietz, Dalton J Surmeier, Eric J Nestler, Angus C Nairn, Paul Greengard, Yong Ki. WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 6. 2018-04-16. PMID:28115704. |
upon an acute challenge of cocaine following chronic cocaine exposure and withdrawal, we also observed in wt, but not in wave1 d1-ko mice, a decrease in dendritic spine density and a decrease in the frequency of excitatory postsynaptic ampa receptor currents in medium spiny projection neurons expressing the d1 dopamine receptor (d1-msns) in the nucleus accumbens. |
2018-04-16 |
2023-08-13 |
mouse |
| Bo Ram Cho, Hyung Shin Yoon, Wha Young Kim, Paul Vezina, Jeong-Hoon Ki. Cocaine inhibits leptin-induced increase of the cocaine- and amphetamine-regulated transcript peptide in the nucleus accumbens in rats. Neuroreport. vol 28. issue 11. 2018-04-05. PMID:28614180. |
cocaine inhibits leptin-induced increase of the cocaine- and amphetamine-regulated transcript peptide in the nucleus accumbens in rats. |
2018-04-05 |
2023-08-13 |
rat |
| Hong-Ju Yang, Hai-Ying Zhang, Guo-Hua Bi, Yi He, Jun-Tao Gao, Zheng-Xiong X. Deletion of Type 2 Metabotropic Glutamate Receptor Decreases Sensitivity to Cocaine Reward in Rats. Cell reports. vol 20. issue 2. 2018-04-03. PMID:28700935. |
mglur2 mutant rats also show a lower propensity to relapse after a period of cocaine abstinence, an effect associated with reduced cocaine-induced dopamine and glutamate overflow in the nucleus accumbens. |
2018-04-03 |
2023-08-13 |
rat |
| Qianqian Fang, Jianli Wan. Place preferences associated with pups or cocaine change the expression of D2R, V1aR and OTR in the NAcc and MeA and the levels of plasma AVP, OT, T and E2 in mandarin vole fathers. Psychoneuroendocrinology. vol 80. 2018-03-14. PMID:28371737. |
the aims of this study were to examine the protein expression levels of the da 2-type receptor (d2r), avp receptor 1a(v1ar) and ot receptor (otr) in the nucleus accumbens (nacc) and medial amygdala (mea) as well as the plasma hormone responses after mandarin vole fathers were conditioned with their pups or cocaine. |
2018-03-14 |
2023-08-13 |
Not clear |
| HaoSheng Sun, Diane M Damez-Werno, Kimberly N Scobie, Ning-Yi Shao, Caroline Dias, Jacqui Rabkin, Katherine N Wright, Ezekiell Mouzon, Mohamed Kabbaj, Rachael Neve, Gustavo Turecki, Li Shen, Eric J Nestle. Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine. Neuroscience. vol 353. 2018-03-14. PMID:28412501. |
regulation of baz1a and nucleosome positioning in the nucleus accumbens in response to cocaine. |
2018-03-14 |
2023-08-13 |
mouse |
| HaoSheng Sun, Diane M Damez-Werno, Kimberly N Scobie, Ning-Yi Shao, Caroline Dias, Jacqui Rabkin, Katherine N Wright, Ezekiell Mouzon, Mohamed Kabbaj, Rachael Neve, Gustavo Turecki, Li Shen, Eric J Nestle. Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine. Neuroscience. vol 353. 2018-03-14. PMID:28412501. |
here we demonstrate that baz1a, an accessory subunit of the iswi family of chromatin remodeling complexes, is downregulated in the nucleus accumbens (nac) of mice exposed repeatedly to cocaine and of cocaine-addicted humans. |
2018-03-14 |
2023-08-13 |
mouse |
| Samantha M Fortin, Mitchell F Roitma. Central GLP-1 receptor activation modulates cocaine-evoked phasic dopamine signaling in the nucleus accumbens core. Physiology & behavior. vol 176. 2018-03-08. PMID:28315693. |
here, we use fast-scan cyclic voltammetry (fscv) to explore glp-1 receptor (glp-1r) modulation of dynamic dopamine release in the nucleus accumbens (nac) during cocaine administration. |
2018-03-08 |
2023-08-13 |
Not clear |
| R J Taugher, Y Lu, R Fan, A Ghobbeh, C J Kreple, F M Faraci, J A Wemmi. ASIC1A in neurons is critical for fear-related behaviors. Genes, brain, and behavior. vol 16. issue 8. 2018-02-22. PMID:28657172. |
in contrast, in the nucleus accumbens asic1a expression was relatively normal in synasic1a ko mice, and consistent with this observation, cocaine conditioned place preference (cpp) was normal. |
2018-02-22 |
2023-08-13 |
mouse |
| Jamie M Gauthier, Amy Lin, Bríd Á Nic Dhonnchadha, Roger D Spealman, Heng-Ye Man, Kathleen M Kanta. Environmental enrichment facilitates cocaine-cue extinction, deters reacquisition of cocaine self-administration and alters AMPAR GluA1 expression and phosphorylation. Addiction biology. vol 22. issue 1. 2018-02-13. PMID:26384129. |
cocaine self-administration alone decreased total glua1 and/or pser845glua1 expression in basolateral amygdala and nucleus accumbens. |
2018-02-13 |
2023-08-13 |
rat |
| Megan B Miller, Yan Yan, Kazuya Machida, Drew D Kiraly, Aaron D Levy, Yi I Wu, TuKiet T Lam, Thomas Abbott, Anthony J Koleske, Betty A Eipper, Richard E Main. Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity. ACS chemical neuroscience. vol 8. issue 7. 2018-01-30. PMID:28418645. |
mass spectrometry was used to quantify phosphorylation at 26 sites in kal7 from individual adult rat nucleus accumbens and prefrontal cortex before and after exposure to acute or chronic cocaine. |
2018-01-30 |
2023-08-13 |
rat |
| Diane M Damez-Werno, HaoSheng Sun, Kimberly N Scobie, Ningyi Shao, Jaclyn Rabkin, Caroline Dias, Erin S Calipari, Ian Maze, Catherine J Pena, Deena M Walker, Michael E Cahill, Ramesh Chandra, Amy Gancarz, Ezekiell Mouzon, Joseph A Landry, Hannah Cates, Mary-Kay Lobo, David Dietz, C David Allis, Ernesto Guccione, Gustavo Turecki, Paola Defilippi, Rachael L Neve, Yasmin L Hurd, Li Shen, Eric J Nestle. Histone arginine methylation in cocaine action in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 34. 2018-01-26. PMID:27506785. |
histone arginine methylation in cocaine action in the nucleus accumbens. |
2018-01-26 |
2023-08-13 |
mouse |
| Diane M Damez-Werno, HaoSheng Sun, Kimberly N Scobie, Ningyi Shao, Jaclyn Rabkin, Caroline Dias, Erin S Calipari, Ian Maze, Catherine J Pena, Deena M Walker, Michael E Cahill, Ramesh Chandra, Amy Gancarz, Ezekiell Mouzon, Joseph A Landry, Hannah Cates, Mary-Kay Lobo, David Dietz, C David Allis, Ernesto Guccione, Gustavo Turecki, Paola Defilippi, Rachael L Neve, Yasmin L Hurd, Li Shen, Eric J Nestle. Histone arginine methylation in cocaine action in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 34. 2018-01-26. PMID:27506785. |
repeated cocaine exposure regulates transcriptional regulation within the nucleus accumbens (nac), and epigenetic mechanisms-such as histone acetylation and methylation on lys residues-have been linked to these lasting actions of cocaine. |
2018-01-26 |
2023-08-13 |
mouse |
| Melissa L Perreault, Ahmed Hasbi, Maurice Y F Shen, Theresa Fan, Gemma Navarro, Paul J Fletcher, Rafael Franco, José L Lanciego, Susan R Georg. Disruption of a dopamine receptor complex amplifies the actions of cocaine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 9. 2018-01-18. PMID:27480020. |
cocaine-induced increases in dopamine signaling in nucleus accumbens (nac) play a significant role in cocaine seeking behavior. |
2018-01-18 |
2023-08-13 |
rat |
| Xing Zhang, Veronica M Chiu, Ryan P Todd, Barbara A Sorg, Herbert H Hil. Neuronal metabolomics by ion mobility mass spectrometry in cocaine self-administering rats after early and late withdrawal. Analytical and bioanalytical chemistry. vol 408. issue 16. 2018-01-16. PMID:27108279. |
the neuronal metabolomes in rat striatum (str), prefrontal cortex (pfc), and nucleus accumbens (nac) were analyzed by hadamard transform ion mobility mass spectrometry (ht-imms) in order to reveal global and specific metabolic changes induced by cocaine self-administration after 1-day or 3-week withdrawal. |
2018-01-16 |
2023-08-13 |
rat |
| Zheng-Xiong Xi, Rui Song, Xia Li, Guan-Yi Lu, Xiao-Qing Peng, Yi He, Guo-Hua Bi, Siyuan Peter Sheng, Hong-Ju Yang, Haiying Zhang, Jin Li, Mark Froimowitz, Eliot L Gardne. CTDP-32476: A Promising Agonist Therapy for Treatment of Cocaine Addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27534265. |
pretreatment with ctdp-32476 inhibited cocaine self-administration, cocaine-associated cue-induced relapse to drug seeking, and cocaine-enhanced extracellular da in the nucleus accumbens. |
2018-01-16 |
2023-08-13 |
rat |
| Daniel T Christian, Xiaoting Wang, Eugenia L Chen, Lakshya K Sehgal, Michael N Ghassemlou, Julia J Miao, Derenik Estepanian, Cameron H Araghi, Grace E Stutzmann, Marina E Wol. Dynamic Alterations of Rat Nucleus Accumbens Dendritic Spines over 2 Months of Abstinence from Extended-Access Cocaine Self-Administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27555380. |
dynamic alterations of rat nucleus accumbens dendritic spines over 2 months of abstinence from extended-access cocaine self-administration. |
2018-01-16 |
2023-08-13 |
rat |
| Daniel T Christian, Xiaoting Wang, Eugenia L Chen, Lakshya K Sehgal, Michael N Ghassemlou, Julia J Miao, Derenik Estepanian, Cameron H Araghi, Grace E Stutzmann, Marina E Wol. Dynamic Alterations of Rat Nucleus Accumbens Dendritic Spines over 2 Months of Abstinence from Extended-Access Cocaine Self-Administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27555380. |
chronic cocaine exposure influences the density and morphology of dendritic spines on medium spiny neurons (msns) in the nucleus accumbens (nac), a critical brain region for cocaine craving. |
2018-01-16 |
2023-08-13 |
rat |