| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rachel M Haake, Elizabeth A West, Xuefei Wang, Regina M Carell. Drug-induced dysphoria is enhanced following prolonged cocaine abstinence and dynamically tracked by nucleus accumbens neurons. Addiction biology. vol 24. issue 4. 2020-08-10. PMID:29717793. |
drug-induced dysphoria is enhanced following prolonged cocaine abstinence and dynamically tracked by nucleus accumbens neurons. |
2020-08-10 |
2023-08-13 |
rat |
| Rachel M Haake, Elizabeth A West, Xuefei Wang, Regina M Carell. Drug-induced dysphoria is enhanced following prolonged cocaine abstinence and dynamically tracked by nucleus accumbens neurons. Addiction biology. vol 24. issue 4. 2020-08-10. PMID:29717793. |
in a pre-clinical model, rats exhibit negative affect to a normally rewarding tastant when it predicts impending, but delayed cocaine, and nucleus accumbens (nac) neurons dynamically track this state. |
2020-08-10 |
2023-08-13 |
rat |
| Mathieu E Wimmer, Fair M Vassoler, Samantha L White, Heath D Schmidt, Simone Sidoli, Yumiao Han, Benjamin A Garcia, R Christopher Pierc. Impaired cocaine-induced behavioral plasticity in the male offspring of cocaine-experienced sires. The European journal of neuroscience. vol 49. issue 9. 2020-07-14. PMID:30565761. |
the reduced cocaine sensitization phenotype in male progeny was associated with changes in histone post-translational modifications, epigenetic processes that regulate gene expression by controlling the accessibility of genes to transcriptional machinery, in the nucleus accumbens of first-generation male progeny. |
2020-07-14 |
2023-08-13 |
Not clear |
| Andre U Deutschmann, Jeffrey D Lenz, Anna G McGrath, Lisa A Brian. Reversing Cocaine-Induced Plasticity with Zeta Inhibitory Peptide. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 39. 2020-07-06. PMID:31409665. |
the current study examined the effect of zip administration in the nucleus accumbens on reinstatement (ri) of cocaine seeking, a rodent model of relapse. |
2020-07-06 |
2023-08-13 |
mouse |
| Mathieu E Wimmer, Bruno Fant, Sarah E Swinford-Jackson, Alexander Testino, Duncan Van Nest, Ted Abel, R Christopher Pierc. H3.3 Barcoding of Nucleus Accumbens Transcriptional Activity Identifies Novel Molecular Cascades Associated with Cocaine Self-administration in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 27. 2020-06-15. PMID:31043484. |
h3.3 barcoding of nucleus accumbens transcriptional activity identifies novel molecular cascades associated with cocaine self-administration in mice. |
2020-06-15 |
2023-08-13 |
mouse |
| Puja K Parekh, Ryan W Logan, Kyle D Ketchesin, Darius Becker-Krail, Micah A Shelton, Mariah A Hildebrand, Kelly Barko, Yanhua H Huang, Colleen A McClun. Cell-Type-Specific Regulation of Nucleus Accumbens Synaptic Plasticity and Cocaine Reward Sensitivity by the Circadian Protein, NPAS2. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 24. 2020-06-12. PMID:30962277. |
cell-type-specific regulation of nucleus accumbens synaptic plasticity and cocaine reward sensitivity by the circadian protein, npas2. |
2020-06-12 |
2023-08-13 |
Not clear |
| Alexandra M Yaw, Rebecca A Prosser, Piet C Jones, Benjamin J Garcia, Daniel A Jacobson, J David Glas. Epigenetic effects of paternal cocaine on reward stimulus behavior and accumbens gene expression in mice. Behavioural brain research. vol 367. 2020-06-08. PMID:30910707. |
this study, utilizing a murine (c57bl/6j) oral cocaine model, examines the effects of paternal cocaine exposure on fundamental characteristics of offspring reward responses, including: 1) the extent of cocaine-induced effects after different durations of sire drug withdrawal; 2) sex- and drug-dependent differences in f1 reward preference; 3) effects on second generation (f2) cocaine preference; and 4) corresponding changes in reward area (nucleus accumbens) mrna expression. |
2020-06-08 |
2023-08-13 |
mouse |
| C T Werner, S Mitra, J A Martin, A F Stewart, A E Lepack, A Ramakrishnan, P H Gobira, Z-J Wang, R L Neve, A M Gancarz, L Shen, I Maze, D M Diet. Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving. Science advances. vol 5. issue 10. 2020-05-19. PMID:31633032. |
ubiquitin-proteasomal regulation of chromatin remodeler ino80 in the nucleus accumbens mediates persistent cocaine craving. |
2020-05-19 |
2023-08-13 |
Not clear |
| C T Werner, S Mitra, J A Martin, A F Stewart, A E Lepack, A Ramakrishnan, P H Gobira, Z-J Wang, R L Neve, A M Gancarz, L Shen, I Maze, D M Diet. Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving. Science advances. vol 5. issue 10. 2020-05-19. PMID:31633032. |
neuroadaptations in the nucleus accumbens (nac) underlie cue-induced cocaine craving that intensifies ("incubates") during abstinence and is believed to contribute to persistent relapse vulnerability. |
2020-05-19 |
2023-08-13 |
Not clear |
| Nicole S Hernandez, Bernadette O'Donovan, Pavel I Ortinski, Heath D Schmid. Activation of glucagon-like peptide-1 receptors in the nucleus accumbens attenuates cocaine seeking in rats. Addiction biology. vol 24. issue 2. 2020-05-08. PMID:29226617. |
activation of glucagon-like peptide-1 receptors in the nucleus accumbens attenuates cocaine seeking in rats. |
2020-05-08 |
2023-08-13 |
rat |
| Ernesto Solis, Anum Afzal, Eugene A Kiyatki. Intravenous Cocaine Increases Oxygen Entry into Brain Tissue: Critical Role of Peripheral Drug Actions. ACS chemical neuroscience. vol 10. issue 4. 2020-04-24. PMID:30040399. |
we employed oxygen sensors coupled with high-speed amperometery to examine the effects of standard cocaine hcl that easily enters the blood-brain barrier and its blood-brain barrier-impermeable methiodide analogue on oxygen levels in the nucleus accumbens in awake, freely moving rats. |
2020-04-24 |
2023-08-13 |
rat |
| Dasiel O Borroto-Escuela, Karolina Wydra, Wilber Romero-Fernandez, Zilong Zhou, Malgorzata Frankowska, Malgorzata Filip, Kjell Fux. A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration. International journal of molecular sciences. vol 20. issue 23. 2020-04-16. PMID:31816953. |
it was previously demonstrated that rat adenosine a2ar transmembrane v peptide administration into the nucleus accumbens enhances cocaine self-administration through disruption of the a2ar-dopamine (d2r) heteroreceptor complex of this region. |
2020-04-16 |
2023-08-13 |
human |
| William J Wright, Nicholas M Graziane, Peter A Neumann, Peter J Hamilton, Hannah M Cates, Lauren Fuerst, Alexander Spenceley, Natalie MacKinnon-Booth, Kartik Iyer, Yanhua H Huang, Yavin Shaham, Oliver M Schlüter, Eric J Nestler, Yan Don. Silent synapses dictate cocaine memory destabilization and reconsolidation. Nature neuroscience. vol 23. issue 1. 2020-04-13. PMID:31792465. |
to explore the synaptic underpinnings for these memory dynamics, we studied ampa receptor (ampar)-silent excitatory synapses, which are generated in the nucleus accumbens by cocaine self-administration, and subsequently mature after prolonged withdrawal by recruiting ampars, echoing acquisition and consolidation of cocaine memories. |
2020-04-13 |
2023-08-13 |
Not clear |
| Anna Kruyer, Lauren E Ball, Danyelle M Townsend, Peter W Kalivas, Joachim D Uy. Post-translational S-glutathionylation of cofilin increases actin cycling during cocaine seeking. PloS one. vol 14. issue 9. 2020-04-02. PMID:31550273. |
using this technique, we show that cofilin in the rat nucleus accumbens undergoes s-glutathionylation during 15-minutes of cued cocaine seeking in the absence of cocaine. |
2020-04-02 |
2023-08-13 |
rat |
| Jacqueline-Marie N Ferland, Tristan J Hynes, Celine D Hounjet, David Lindenbach, Cole Vonder Haar, Wendy K Adams, Anthony G Phillips, Catharine A Winstanle. Prior Exposure to Salient Win-Paired Cues in a Rat Gambling Task Increases Sensitivity to Cocaine Self-Administration and Suppresses Dopamine Efflux in Nucleus Accumbens: Support for the Reward Deficiency Hypothesis of Addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 10. 2020-03-23. PMID:30626700. |
prior exposure to salient win-paired cues in a rat gambling task increases sensitivity to cocaine self-administration and suppresses dopamine efflux in nucleus accumbens: support for the reward deficiency hypothesis of addiction. |
2020-03-23 |
2023-08-13 |
rat |
| Conor H Murray, Jessica A Loweth, Mike Milovanovic, Michael T Stefanik, Aaron J Caccamise, Hubert Dolubizno, Jonathan R Funke, M Foster Olive, Marina E Wol. AMPA receptor and metabotropic glutamate receptor 1 adaptations in the nucleus accumbens core during incubation of methamphetamine craving. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 9. 2020-03-17. PMID:31146278. |
for cocaine and methamphetamine, expression of incubated craving ultimately depends on strengthening of nucleus accumbens (nac) synapses through an accumulation of high conductance ca |
2020-03-17 |
2023-08-13 |
Not clear |
| Bruno G Berardino, Estefanía A Fesser, Laura M Belluscio, Octavio Gianatiempo, Nicolás Pregi, Eduardo T Cánep. Effects of cocaine base paste on anxiety-like behavior and immediate-early gene expression in nucleus accumbens and medial prefrontal cortex of female mice. Psychopharmacology. vol 236. issue 12. 2020-03-03. PMID:31280332. |
effects of cocaine base paste on anxiety-like behavior and immediate-early gene expression in nucleus accumbens and medial prefrontal cortex of female mice. |
2020-03-03 |
2023-08-13 |
mouse |
| Paul Girardeau, Sylvia Navailles, Audrey Durand, Caroline Vouillac-Mendoza, Karine Guillem, Serge H Ahme. Relapse to cocaine use persists following extinction of drug-primed craving. Neuropharmacology. vol 155. 2020-02-28. PMID:31167108. |
this lack of effect occurred despite evidence for post-extinction loss of neuronal responses to cocaine priming in brain regions causally involved in cocaine reinstatement (i.e., the dorsomedial prefrontal cortex and the core of the nucleus accumbens). |
2020-02-28 |
2023-08-13 |
rat |
| Hannah M Cates, Casey K Lardner, Rosemary C Bagot, Rachael L Neve, Eric J Nestle. eNeuro. vol 6. issue 2. 2020-02-10. PMID:30963104. |
in this study, we find a novel regulatory role for the transcription factor e2f3, recently implicated in transcriptional regulation by cocaine, in controlling Δfosb induction in the mouse nucleus accumbens (nac) following cocaine administration. |
2020-02-10 |
2023-08-13 |
mouse |
| Yiming Zhou, Huiwen Zhu, Zhiyuan Liu, Xi Chen, XiuJuan Su, Chaonan Ma, Zhen Tian, Bing Huang, Enhui Yan, Xing Liu, Lan M. A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine. Nature neuroscience. vol 22. issue 12. 2020-01-31. PMID:31719672. |
here we tagged engram cells in the ventral ca1 region of the hippocampus (vca1) and the core of the nucleus accumbens (acbc) during cocaine conditioned place preference (cpp) training and show that the vca1 engram projects preferentially to the acbc and that the engram circuit from the vca1 to the acbc mediates memory recall. |
2020-01-31 |
2023-08-13 |
Not clear |