| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lan-Yuan Zhang, Yue-Qing Zhou, Zhi-Peng Yu, Xiao-Qin Zhang, Jie Shi, Hao-Wei She. Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 5. 2021-06-23. PMID:33514875. |
restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats. |
2021-06-23 |
2023-08-13 |
rat |
| José Pedro Prieto, Ximena López Hill, Jessika Urbanavicius, Verónica Sanchez, Xavier Nadal, Cecilia Scorz. Cannabidiol Prevents the Expression of the Locomotor Sensitization and the Metabolic Changes in the Nucleus Accumbens and Prefrontal Cortex Elicited by the Combined Administration of Cocaine and Caffeine in Rats. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32415526. |
cannabidiol prevents the expression of the locomotor sensitization and the metabolic changes in the nucleus accumbens and prefrontal cortex elicited by the combined administration of cocaine and caffeine in rats. |
2021-06-14 |
2023-08-13 |
rat |
| Benoît Forget, Romain Icick, Jonathan Robert, Caroline Correia, Marie S Prevost, Marc Gielen, Pierre-Jean Corringer, Frank Bellivier, Florence Vorspan, Morgane Besson, Uwe Masko. Alterations in nicotinic receptor alpha5 subunit gene differentially impact early and later stages of cocaine addiction: a translational study in transgenic rats and patients. Progress in neurobiology. vol 197. 2021-06-11. PMID:32841724. |
to investigate the link between this subunit and cud, we submitted rats knockout for the α5 subunit gene (α5ko), or carrying the α5snp, to cocaine self-administration (sa) and showed that the acquisition of cocaine-sa was impaired in α5snp rats while α5ko rats exhibited enhanced cocaine-induced relapse associated with altered neuronal activity in the nucleus accumbens. |
2021-06-11 |
2023-08-13 |
human |
| Yao Q Wang, Yanhua H Huang, Saju Balakrishnan, Lidong Liu, Yu Tian Wang, Eric J Nestler, Oliver M Schlüter, Yan Don. AMPA and NMDA Receptor Trafficking at Cocaine-Generated Synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 9. 2021-06-11. PMID:33436529. |
cocaine experience generates ampa receptor (ampar)-silent synapses in the nucleus accumbens (nac), which are thought to be new synaptic contacts enriched in glun2b-containing nmda receptors (nmdars). |
2021-06-11 |
2023-08-13 |
mouse |
| Natalie N Nawarawong, Christopher M Olse. Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex. Behavioural brain research. vol 379. 2021-04-30. PMID:31614186. |
within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex. |
2021-04-30 |
2023-08-13 |
mouse |
| Natalie N Nawarawong, Christopher M Olse. Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex. Behavioural brain research. vol 379. 2021-04-30. PMID:31614186. |
using the tettag mouse model and fos immunohistochemistry, we measured neurons engaged by novelty and acute cocaine exposure, respectively in the prefrontal cortex (pfc) and nucleus accumbens (nac). |
2021-04-30 |
2023-08-13 |
mouse |
| Adriana Castro-Zavala, Ana Martín-Sánchez, Miguel Ángel Luján, Olga Valverd. Maternal separation increases cocaine intake through a mechanism involving plasticity in glutamate signalling. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32329565. |
we also investigated the subsequent alterations on glur2, glur1, camp response element-binding (creb), and creb-phosphorylation (pcreb) in ventral tegmental area (vta) and nucleus accumbens (nac) induced by both msew and cocaine sa. |
2021-03-25 |
2023-08-13 |
mouse |
| Allison R Bechard, Carly N Logan, Javier Mesa, Yasmin Padovan-Hernandez, Harrison Blount, Virginia L Hodges, Lori A Knacksted. Role of prefrontal cortex projections to the nucleus accumbens core in mediating the effects of ceftriaxone on cue-induced cocaine seeking. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32558119. |
ceftriaxone is an antibiotic that reliably attenuates the reinstatement of cocaine seeking after extinction while preventing the nucleus accumbens (na) core glutamate efflux that drives reinstatement. |
2021-03-25 |
2023-08-13 |
rat |
| Inês M Amaral, Cristina Lemos, Isabella Cera, Georg Dechant, Alex Hofer, Rana El Rawa. Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Versus Social Interaction Reward. International journal of molecular sciences. vol 22. issue 1. 2021-03-25. PMID:33396297. |
involvement of camp-dependent protein kinase in the nucleus accumbens in cocaine versus social interaction reward. |
2021-03-25 |
2023-08-13 |
rat |
| Ching Mei Wu, Ted Weita La. Microglia depletion by PLX3397 has no effect on cocaine-induced behavioral sensitization in male mice. Brain research. vol 1761. 2021-03-21. PMID:33639199. |
although cocaine treatment had little effect on microglial abundance, plx3397 treatment dramatically decreased the number of microglia in the nucleus accumbens and hippocampus in control mice and in mice subjected to cocaine sensitization. |
2021-03-21 |
2023-08-13 |
mouse |
| Wendy J Lynch, Anousheh Bakhti-Suroosh, Jean M Abel, Camilla Davi. Shifts in the neurobiological mechanisms motivating cocaine use with the development of an addiction-like phenotype in male rats. Psychopharmacology. vol 238. issue 3. 2021-03-15. PMID:33241478. |
the development of addiction is accompanied by a shift in the mechanisms motivating cocaine use from nucleus accumbens (nac) dopamine d |
2021-03-15 |
2023-08-13 |
rat |
| Irena Smaga, Karolina Wydra, Małgorzata Frankowska, Fabio Fumagalli, Marek Sanak, Małgorzata Fili. Cocaine Self-Administration and Abstinence Modulate NMDA Receptor Subunits and Active Zone Proteins in the Rat Nucleus Accumbens. Molecules (Basel, Switzerland). vol 25. issue 15. 2021-03-10. PMID:32751823. |
cocaine self-administration and abstinence modulate nmda receptor subunits and active zone proteins in the rat nucleus accumbens. |
2021-03-10 |
2023-08-13 |
rat |
| Sunil U Nayak, Stephanie Cicalese, Chris Tallarida, Chicora F Oliver, Scott M Rawl. Chemokine CCR5 and cocaine interactions in the brain: Cocaine enhances mesolimbic CCR5 mRNA levels and produces place preference and locomotor activation that are reduced by a CCR5 antagonist. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31557508. |
in rats treated repeatedly with cocaine (10 mg/kg × 4 days, ip), ccr5 gene expression was upregulated in the nucleus accumbens and ventral tegmental area but mrna levels of ccr5 ligands (i.e., ccl3, ccl4 and ccl5) were not affected. |
2021-03-08 |
2023-08-13 |
mouse |
| Joo Han Lee, Efrain A Ribeiro, Jeongseop Kim, Bumjin Ko, Hope Kronman, Yun Ha Jeong, Jong Kyoung Kim, Patricia H Janak, Eric J Nestler, Ja Wook Koo, Joung-Hun Ki. Dopaminergic Regulation of Nucleus Accumbens Cholinergic Interneurons Demarcates Susceptibility to Cocaine Addiction. Biological psychiatry. vol 88. issue 10. 2021-03-08. PMID:32622465. |
dopaminergic regulation of nucleus accumbens cholinergic interneurons demarcates susceptibility to cocaine addiction. |
2021-03-08 |
2023-08-13 |
Not clear |
| David Roura-Martínez, Marcos Ucha, Javier Orihuel, Inmaculada Ballesteros-Yáñez, Carlos Alberto Castillo, Alberto Marcos, Emilio Ambrosio, Alejandro Higuera-Mata. Central nucleus of the amygdala as a common substrate of the incubation of drug and natural reinforcer seeking. Addiction biology. vol 25. issue 2. 2021-02-16. PMID:30623520. |
lewis rats were used to study the effects of cocaine, heroin, and sucrose seeking incubation on six key brain regions: the nucleus accumbens shell/core, central/basolateral amygdala, and dorsomedial/ventromedial prefrontal cortex. |
2021-02-16 |
2023-08-13 |
rat |
| Shuang-Qi Gao, Hai Zhang, Jin-Gang He, Hui-Ling Zheng, Pei-Wei Zhang, Jun-Feng Xu, Zu-Cheng Shen, Huan-Huan Zhao, Fang Wang, Zhuang-Li Hu, Jian-Guo Che. Neuronal HMGB1 in nucleus accumbens regulates cocaine reward memory. Addiction biology. vol 25. issue 2. 2021-02-16. PMID:31056833. |
neuronal hmgb1 in nucleus accumbens regulates cocaine reward memory. |
2021-02-16 |
2023-08-13 |
Not clear |
| Shuang-Qi Gao, Hai Zhang, Jin-Gang He, Hui-Ling Zheng, Pei-Wei Zhang, Jun-Feng Xu, Zu-Cheng Shen, Huan-Huan Zhao, Fang Wang, Zhuang-Li Hu, Jian-Guo Che. Neuronal HMGB1 in nucleus accumbens regulates cocaine reward memory. Addiction biology. vol 25. issue 2. 2021-02-16. PMID:31056833. |
here, we show that cocaine exposure induced the translocation and release of hmgb1 in the nucleus accumbens (nac) neurons. |
2021-02-16 |
2023-08-13 |
Not clear |
| Mari Urb, Kerly Niinep, Terje Matsalu, Karin Kipper, Koit Herodes, Alexander Zharkovsky, Tõnis Timmusk, Kaili Anier, Anti Kald. The role of DNA methyltransferase activity in cocaine treatment and withdrawal in the nucleus accumbens of mice. Addiction biology. vol 25. issue 1. 2021-02-10. PMID:30730091. |
the role of dna methyltransferase activity in cocaine treatment and withdrawal in the nucleus accumbens of mice. |
2021-02-10 |
2023-08-13 |
mouse |
| Ilse Delint-Ramirez, Francisco Garcia-Oscos, Amir Segev, Saïd Kourric. Cocaine engages a non-canonical, dopamine-independent, mechanism that controls neuronal excitability in the nucleus accumbens. Molecular psychiatry. vol 25. issue 3. 2021-01-14. PMID:29880884. |
cocaine engages a non-canonical, dopamine-independent, mechanism that controls neuronal excitability in the nucleus accumbens. |
2021-01-14 |
2023-08-13 |
Not clear |
| Michel Engeln, Swarup Mitra, Ramesh Chandra, Utsav Gyawali, Megan E Fox, David M Dietz, Mary Kay Lob. Sex-Specific Role for Egr3 in Nucleus Accumbens D2-Medium Spiny Neurons Following Long-Term Abstinence From Cocaine Self-administration. Biological psychiatry. vol 87. issue 11. 2021-01-06. PMID:31858986. |
sex-specific role for egr3 in nucleus accumbens d2-medium spiny neurons following long-term abstinence from cocaine self-administration. |
2021-01-06 |
2023-08-13 |
Not clear |