| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Horia Pribiag, Sora Shin, Eric Hou-Jen Wang, Fangmiao Sun, Paul Datta, Alexander Okamoto, Hayden Guss, Akanksha Jain, Xiao-Yun Wang, Bruna De Freitas, Patrick Honma, Stefan Pate, Varoth Lilascharoen, Yulong Li, Byung Kook Li. Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking. Neuron. vol 109. issue 13. 2021-07-23. PMID:34048697. |
here, we demonstrate that dopamine receptor d3 (drd3)-dependent plasticity in the ventral pallidum (vp) drives potentiation of dopamine release in the nucleus accumbens during relapse to cocaine seeking after abstinence. |
2021-07-23 |
2023-08-13 |
Not clear |
| Silas A Buck, Mary M Torregrossa, Ryan W Logan, Zachary Freyber. Roles of dopamine and glutamate co-release in the nucleus accumbens in mediating the actions of drugs of abuse. The FEBS journal. vol 288. issue 5. 2021-07-20. PMID:32702182. |
here, we summarize how drugs of abuse, particularly cocaine, opioids, and alcohol, alter da release in the nucleus accumbens medial shell, examine the potential role of da/glutamate co-release in mediating these effects, and discuss future directions for further investigating these mechanisms. |
2021-07-20 |
2023-08-13 |
Not clear |
| Santiago Cuesta, Alejandrina Funes, Alejandra M Pacchion. Social Isolation in Male Rats During Adolescence Inhibits the Wnt/β-Catenin Pathway in the Prefrontal Cortex and Enhances Anxiety and Cocaine-Induced Plasticity in Adulthood. Neuroscience bulletin. vol 36. issue 6. 2021-07-19. PMID:32078732. |
furthermore, after the expression of cocaine sensitization, isolated rats showed an increase in this pathway in the nucleus accumbens. |
2021-07-19 |
2023-08-13 |
rat |
| Bethania Mongi-Bragato, María Paula Avalos, Andrea S Guzmán, Constanza García-Keller, Flavia A Bollati, Liliana M Cancel. Endogenous enkephalin is necessary for cocaine-induced alteration in glutamate transmission within the nucleus accumbens. The European journal of neuroscience. vol 53. issue 5. 2021-06-28. PMID:33159343. |
altered glutamate transmission within the nucleus accumbens (nac) has been proposed as a central mechanism underlying behavioural sensitisation associated with repeated cocaine exposure. |
2021-06-28 |
2023-08-13 |
mouse |
| Daiana Rigoni, Maria P Avalos, Maria J Boezio, Andrea S Guzmán, Gaston D Calfa, Eduardo M Perassi, Silvia M Pierotti, Mariano Bisbal, Constanza Garcia-Keller, Liliana M Cancela, Flavia Bollat. Stress-induced vulnerability to develop cocaine addiction depends on cofilin modulation. Neurobiology of stress. vol 15. 2021-06-26. PMID:34169122. |
the actin cytoskeleton remodeling in the nucleus accumbens (na) has been implicated in the expression of stress-induced cross-sensitization with cocaine. |
2021-06-26 |
2023-08-13 |
rat |
| Yanaira Alonso-Caraballo, Tracy L Fetterly, Emily T Jorgensen, Allison M Nieto, Travis E Brown, Carrie R Ferrari. Sex specific effects of "junk-food" diet on calcium permeable AMPA receptors and silent synapses in the nucleus accumbens core. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 3. 2021-06-23. PMID:32731252. |
cp-ampars in the nucleus accumbens (nac) mediate cue-triggered motivation for food and cocaine. |
2021-06-23 |
2023-08-13 |
rat |
| Ludivine Canchy, Paul Girardeau, Audrey Durand, Caroline Vouillac-Mendoza, Serge H Ahme. Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:32731253. |
first, a systematic literature analysis revealed that the delays of effects of intravenous cocaine on nucleus accumbens dopamine are of the order of tens of seconds and are considerably longer than those of nondrug reward. |
2021-06-23 |
2023-08-13 |
rat |
| Jerome A J Becker, Lucie P Pellissier, Yannick Corde, Thibaut Laboute, Audrey Léauté, Jorge Gandía, Julie Le Merre. Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure in male mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 7. 2021-06-23. PMID:33349673. |
transcriptional regulation of marker genes of medium spiny neurons (msns) allowed best discriminating between 4-week morphine and cocaine abstinence in the nucleus accumbens (nac). |
2021-06-23 |
2023-08-13 |
mouse |
| Lan-Yuan Zhang, Yue-Qing Zhou, Zhi-Peng Yu, Xiao-Qin Zhang, Jie Shi, Hao-Wei She. Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 5. 2021-06-23. PMID:33514875. |
restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats. |
2021-06-23 |
2023-08-13 |
rat |
| José Pedro Prieto, Ximena López Hill, Jessika Urbanavicius, Verónica Sanchez, Xavier Nadal, Cecilia Scorz. Cannabidiol Prevents the Expression of the Locomotor Sensitization and the Metabolic Changes in the Nucleus Accumbens and Prefrontal Cortex Elicited by the Combined Administration of Cocaine and Caffeine in Rats. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32415526. |
cannabidiol prevents the expression of the locomotor sensitization and the metabolic changes in the nucleus accumbens and prefrontal cortex elicited by the combined administration of cocaine and caffeine in rats. |
2021-06-14 |
2023-08-13 |
rat |
| Benoît Forget, Romain Icick, Jonathan Robert, Caroline Correia, Marie S Prevost, Marc Gielen, Pierre-Jean Corringer, Frank Bellivier, Florence Vorspan, Morgane Besson, Uwe Masko. Alterations in nicotinic receptor alpha5 subunit gene differentially impact early and later stages of cocaine addiction: a translational study in transgenic rats and patients. Progress in neurobiology. vol 197. 2021-06-11. PMID:32841724. |
to investigate the link between this subunit and cud, we submitted rats knockout for the α5 subunit gene (α5ko), or carrying the α5snp, to cocaine self-administration (sa) and showed that the acquisition of cocaine-sa was impaired in α5snp rats while α5ko rats exhibited enhanced cocaine-induced relapse associated with altered neuronal activity in the nucleus accumbens. |
2021-06-11 |
2023-08-13 |
human |
| Yao Q Wang, Yanhua H Huang, Saju Balakrishnan, Lidong Liu, Yu Tian Wang, Eric J Nestler, Oliver M Schlüter, Yan Don. AMPA and NMDA Receptor Trafficking at Cocaine-Generated Synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 9. 2021-06-11. PMID:33436529. |
cocaine experience generates ampa receptor (ampar)-silent synapses in the nucleus accumbens (nac), which are thought to be new synaptic contacts enriched in glun2b-containing nmda receptors (nmdars). |
2021-06-11 |
2023-08-13 |
mouse |
| Natalie N Nawarawong, Christopher M Olse. Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex. Behavioural brain research. vol 379. 2021-04-30. PMID:31614186. |
within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex. |
2021-04-30 |
2023-08-13 |
mouse |
| Natalie N Nawarawong, Christopher M Olse. Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex. Behavioural brain research. vol 379. 2021-04-30. PMID:31614186. |
using the tettag mouse model and fos immunohistochemistry, we measured neurons engaged by novelty and acute cocaine exposure, respectively in the prefrontal cortex (pfc) and nucleus accumbens (nac). |
2021-04-30 |
2023-08-13 |
mouse |
| Adriana Castro-Zavala, Ana Martín-Sánchez, Miguel Ángel Luján, Olga Valverd. Maternal separation increases cocaine intake through a mechanism involving plasticity in glutamate signalling. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32329565. |
we also investigated the subsequent alterations on glur2, glur1, camp response element-binding (creb), and creb-phosphorylation (pcreb) in ventral tegmental area (vta) and nucleus accumbens (nac) induced by both msew and cocaine sa. |
2021-03-25 |
2023-08-13 |
mouse |
| Allison R Bechard, Carly N Logan, Javier Mesa, Yasmin Padovan-Hernandez, Harrison Blount, Virginia L Hodges, Lori A Knacksted. Role of prefrontal cortex projections to the nucleus accumbens core in mediating the effects of ceftriaxone on cue-induced cocaine seeking. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32558119. |
ceftriaxone is an antibiotic that reliably attenuates the reinstatement of cocaine seeking after extinction while preventing the nucleus accumbens (na) core glutamate efflux that drives reinstatement. |
2021-03-25 |
2023-08-13 |
rat |
| Inês M Amaral, Cristina Lemos, Isabella Cera, Georg Dechant, Alex Hofer, Rana El Rawa. Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Versus Social Interaction Reward. International journal of molecular sciences. vol 22. issue 1. 2021-03-25. PMID:33396297. |
involvement of camp-dependent protein kinase in the nucleus accumbens in cocaine versus social interaction reward. |
2021-03-25 |
2023-08-13 |
rat |
| Ching Mei Wu, Ted Weita La. Microglia depletion by PLX3397 has no effect on cocaine-induced behavioral sensitization in male mice. Brain research. vol 1761. 2021-03-21. PMID:33639199. |
although cocaine treatment had little effect on microglial abundance, plx3397 treatment dramatically decreased the number of microglia in the nucleus accumbens and hippocampus in control mice and in mice subjected to cocaine sensitization. |
2021-03-21 |
2023-08-13 |
mouse |
| Wendy J Lynch, Anousheh Bakhti-Suroosh, Jean M Abel, Camilla Davi. Shifts in the neurobiological mechanisms motivating cocaine use with the development of an addiction-like phenotype in male rats. Psychopharmacology. vol 238. issue 3. 2021-03-15. PMID:33241478. |
the development of addiction is accompanied by a shift in the mechanisms motivating cocaine use from nucleus accumbens (nac) dopamine d |
2021-03-15 |
2023-08-13 |
rat |
| Irena Smaga, Karolina Wydra, Małgorzata Frankowska, Fabio Fumagalli, Marek Sanak, Małgorzata Fili. Cocaine Self-Administration and Abstinence Modulate NMDA Receptor Subunits and Active Zone Proteins in the Rat Nucleus Accumbens. Molecules (Basel, Switzerland). vol 25. issue 15. 2021-03-10. PMID:32751823. |
cocaine self-administration and abstinence modulate nmda receptor subunits and active zone proteins in the rat nucleus accumbens. |
2021-03-10 |
2023-08-13 |
rat |