| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karen K Szumlinski, Daria L Thompson, Rachel M Renton, Alexis W Ary, Kevin D Lomina. Enduring dysregulation of nucleus accumbens catecholamine and glutamate transmission by developmental exposure to phenylpropanolamine. Brain research. vol 1748. 2021-10-25. PMID:32896521. |
previously, we reported that juvenile ppa exposure alters the developmental trajectory of catecholamine and amino acid neurotransmitter systems in the nucleus accumbens (nac), impacting the motivational valence of cocaine in later life. |
2021-10-25 |
2023-08-13 |
mouse |
| Molly Estill, Efrain Ribeiro, Nancy J Francoeur, Melissa L Smith, Robert Sebra, Szu-Ying Yeh, Ashley M Cunningham, Eric J Nestler, Li She. Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment. Scientific reports. vol 11. issue 1. 2021-10-25. PMID:33762610. |
long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment. |
2021-10-25 |
2023-08-13 |
mouse |
| Molly Estill, Efrain Ribeiro, Nancy J Francoeur, Melissa L Smith, Robert Sebra, Szu-Ying Yeh, Ashley M Cunningham, Eric J Nestler, Li She. Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment. Scientific reports. vol 11. issue 1. 2021-10-25. PMID:33762610. |
to better understand the full-length transcriptome of the nucleus accumbens (nac)-a key brain reward region-in chronic cocaine treatment, we perform the first single molecule, long-read sequencing analysis using the iso-seq method to detect 42,114 unique transcripts from mouse nac polyadenylated rna. |
2021-10-25 |
2023-08-13 |
mouse |
| Jonathan J Chow, Rebecca S Hofford, Joshua S Beckman. Neuronal activity associated with cocaine preference: Effects of differential cocaine intake. Neuropharmacology. vol 184. 2021-10-22. PMID:33340530. |
herein, a choice procedure that controls for cocaine intake was utilized to explore if neuronal activity, measured as cfos expression in the orbitofrontal cortex (ofc) and nucleus accumbens (nac), was reflective of preference. |
2021-10-22 |
2023-08-13 |
human |
| Yao-Ying Ma, Sandy M Henley, Jeff Toll, James D Jentsch, Christopher J Evans, Michael S Levine, Carlos Ceped. Erratum: Drug-primed reinstatement of cocaine seeking in mice: increased excitability of mediumsized spiny neurons in the nucleus accumbens. ASN neuro. vol 5. issue 4. 2021-10-21. PMID:24327823. |
erratum: drug-primed reinstatement of cocaine seeking in mice: increased excitability of mediumsized spiny neurons in the nucleus accumbens. |
2021-10-21 |
2023-08-12 |
mouse |
| Conor H Murray, Andrew D Gaulden, Alex B Kawa, Mike Milovanovic, Aaron J Caccamise, Jonathan R Funke, Sachin Patel, Marina E Wol. CaMKII Modulates Diacylglycerol Lipase-α Activity in the Rat Nucleus Accumbens after Incubation of Cocaine Craving. eNeuro. vol 8. issue 5. 2021-10-20. PMID:34544759. |
camkii modulates diacylglycerol lipase-α activity in the rat nucleus accumbens after incubation of cocaine craving. |
2021-10-20 |
2023-08-13 |
rat |
| Conor H Murray, Andrew D Gaulden, Alex B Kawa, Mike Milovanovic, Aaron J Caccamise, Jonathan R Funke, Sachin Patel, Marina E Wol. CaMKII Modulates Diacylglycerol Lipase-α Activity in the Rat Nucleus Accumbens after Incubation of Cocaine Craving. eNeuro. vol 8. issue 5. 2021-10-20. PMID:34544759. |
incubation of cocaine craving involves the strengthening of excitatory synapses onto nucleus accumbens (nac) medium spiny neurons via postsynaptic accumulation of high-conductance ca |
2021-10-20 |
2023-08-13 |
rat |
| Kevin M Manz, Benjamin C Coleman, Alexis N Jameson, Dipanwita G Ghose, Sachin Patel, Brad A Gruete. Cocaine restricts nucleus accumbens feedforward drive through a monoamine-independent mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-10-16. PMID:34545194. |
cocaine restricts nucleus accumbens feedforward drive through a monoamine-independent mechanism. |
2021-10-16 |
2023-08-13 |
mouse |
| Shruthi A Thomas, Carlos M Curay, Eugene A Kiyatki. Relationships between oxygen changes in the brain and periphery following physiological activation and the actions of heroin and cocaine. Scientific reports. vol 11. issue 1. 2021-10-12. PMID:33737657. |
animals chronically implanted with oxygen sensors in the nucleus accumbens (nac) and subcutaneous (sc) space were subjected to several mildly arousing stimuli (sound, tail-pinch and social interaction) and intravenous injections of cocaine and heroin. |
2021-10-12 |
2023-08-13 |
rat |
| Swarup Mitra, Pedro H Gobira, Craig T Werner, Jennifer A Martin, Madoka Iida, Shruthi A Thomas, Kyra Erias, Sophia Miracle, Charles Lafargue, Chunna An, David M Diet. A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue-induced cocaine craving following prolonged abstinence. Addiction biology. vol 26. issue 5. 2021-10-06. PMID:33496035. |
here, we investigated how pharmacological manipulation of lipases involved in regulating the expression of the endocannabinoid 2-ag in the nucleus accumbens (nac) influence cocaine relapse via discrete neuroadaptations. |
2021-10-06 |
2023-08-13 |
Not clear |
| Shruthi A Thomas, David Perekopskiy, Eugene A Kiyatki. Cocaine added to heroin fails to affect heroin-induced brain hypoxia. Brain research. vol 1746. 2021-10-01. PMID:32645379. |
here, we used high-speed amperometry with oxygen sensors to examine changes in oxygen concentrations in the nucleus accumbens (nac) induced by intravenous (iv) cocaine, heroin, and their mixtures in freely-moving rats. |
2021-10-01 |
2023-08-13 |
rat |
| Leonardo A Guercio, Mathieu E Wimmer, Heath D Schmidt, Sarah E Swinford-Jackson, R Christopher Pierce, Fair M Vassole. Deep brain stimulation of the infralimbic cortex attenuates cocaine priming-induced reinstatement of drug seeking. Brain research. vol 1746. 2021-10-01. PMID:32652146. |
to date, the nucleus accumbens has received the most attention as a potential target region for examining the impact of dbs on cocaine seeking in preclinical models. |
2021-10-01 |
2023-08-13 |
rat |
| Lori A Knackstedt, Lizhen Wu, Jeffrey Rothstein, Svetlana Vidensky, John Gordon, Mercy Ramanjulu, Paul Dunman, Benjamin Blass, Wayne Childers, Magid Abou-Gharbi. MC-100093, a Novel The Journal of pharmacology and experimental therapeutics. vol 378. issue 2. 2021-09-23. PMID:33986035. |
in rodents, the glutamate transporter-1 (glt-1) is downregulated in the nucleus accumbens after cocaine self-administration, and increasing the expression and function of glt-1 reduces the reinstatement of cocaine seeking. |
2021-09-23 |
2023-08-13 |
Not clear |
| Soumyabrata Munshi, J Amiel Rosenkranz, Aaron Caccamise, Marina E Wolf, Claire M Corbett, Jessica A Lowet. Cocaine and chronic stress exposure produce an additive increase in neuronal activity in the basolateral amygdala. Addiction biology. vol 26. issue 1. 2021-09-09. PMID:31750602. |
given that glutamatergic projections from the bla to the nucleus accumbens are critical for the incubation of cue-induced cocaine craving, we hypothesized that cocaine withdrawal and chronic stress exposure produce separate increases that additively increase bla neuronal activity. |
2021-09-09 |
2023-08-13 |
rat |
| Jessica K Shaw, I Pamela Alonso, Stacia I Lewandowski, Marion O Scott, Bethan M O'Connor, Shaili Aggarwal, Mariella De Biasi, Ole V Mortensen, Rodrigo A Españ. Individual differences in dopamine uptake in the dorsomedial striatum prior to cocaine exposure predict motivation for cocaine in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 10. 2021-08-27. PMID:33953341. |
using in vivo voltammetry, we first generated baseline profiles of da release and uptake in the dorsomedial striatum (dms) and nucleus accumbens of drug-naïve male rats prior to exposing them to cocaine using conditioned place preference (cpp) or operant self-administration. |
2021-08-27 |
2023-08-13 |
rat |
| Sumin Sohn, Sunghyun Kim, Ju Hwan Yang, Eun Sang Cho. Linking of NMDA receptors and mGluR5 in the nucleus accumbens core to repeated cocaine-induced 50-kHz ultrasonic vocalization in rats. Addiction biology. 2021-08-25. PMID:34378829. |
this study demonstrated the linking of glutamate receptors in the nucleus accumbens (nac) to vocal expression of 50-khz usv calls after repeated cocaine administration in freely moving rats. |
2021-08-25 |
2023-08-13 |
rat |
| Jessica L Huebschman, Megan C Davis, Catherina Tovar Pensa, Yuhong Guo, Laura N Smit. The fragile X mental retardation protein promotes adjustments in cocaine self-administration that preserve reinforcement level. The European journal of neuroscience. vol 54. issue 3. 2021-08-20. PMID:34133054. |
additionally, we find an fmrp target, the activity-regulated cytoskeleton-associated protein (arc), to be significantly reduced in synaptic cellular fractions prepared from the nucleus accumbens of fmr1 ko, compared with wt, mice following operant tasks reinforced with cocaine but not food. |
2021-08-20 |
2023-08-13 |
mouse |
| Shannon L Cole, Ramesh Chandra, Maya Harris, Ishan Patel, Torrance Wang, Hyunjae Kim, Leah Jensen, Scott J Russo, Gustavo Turecki, Amy M Gancarz-Kausch, David M Dietz, Mary Kay Lob. Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34187517. |
recent studies demonstrate that cocaine affects mitochondrial dynamics and morphological characteristics within the nucleus accumbens (nac). |
2021-08-12 |
2023-08-13 |
human |
| Wei Guo, Hailei Long, Qian Bu, Yinglan Zhao, Hongbo Wang, Jingwei Tian, Xiaobo Ce. Role of BRD4 phosphorylation in the nucleus accumbens in relapse to cocaine-seeking behavior in mice. Addiction biology. vol 25. issue 5. 2021-08-11. PMID:31364211. |
in this study, we found that brd4 phosphorylation in the nucleus accumbens (nac) was closely related to the maintenance of cocaine reinforcement and relapse in different cocaine exposure paradigms. |
2021-08-11 |
2023-08-13 |
mouse |
| Patricia Irizar, Natalia Albein-Urios, José Miguel Martínez-González, Antonio Verdejo-Garcia, Valentina Lorenzett. Unpacking common and distinct neuroanatomical alterations in cocaine dependent versus pathological gambling. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 33. 2021-08-10. PMID:32088112. |
cocaine dependent participants had lower nucleus accumbens and medial orbitofrontal cortex volumes than pathological gamblers (ps <.05, ds = 0.51 and 0.72), with the latter being predicted by higher negative urgency scores. |
2021-08-10 |
2023-08-13 |
human |