All Relations between cocaine and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Javier A Muñiz, José P Prieto, Betina González, Máximo H Sosa, Jean L Cadet, Cecilia Scorza, Francisco J Urbano, Verónica Bisagn. Cocaine and Caffeine Effects on the Conditioned Place Preference Test: Concomitant Changes on Early Genes within the Mouse Prefrontal Cortex and Nucleus Accumbens. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29093669. the goal of the present study was thus to determine caffeine and cocaine combined effects on the conditioned place preference (cpp) test and to determine potential differential mrna expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of immediate-early genes (iegs) as well as dopamine and adenosine receptor subunits. 2020-09-30 2023-08-13 mouse
Ju Hwan Yang, Su Yeon Seo, Jeong Hwan Oh, In Soo Ryu, Jieun Kim, Dong Kun Lee, Yeonhee Ryu, Eun Sang Cho. Activation of Protein Kinase G After Repeated Cocaine Administration Is Necessary for the Phosphorylation of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor GluA1 at Serine 831 in the Rat Nucleus Accumbens. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30104957. activation of protein kinase g after repeated cocaine administration is necessary for the phosphorylation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor glua1 at serine 831 in the rat nucleus accumbens. 2020-09-30 2023-08-13 rat
Ju Hwan Yang, Su Yeon Seo, Jeong Hwan Oh, In Soo Ryu, Jieun Kim, Dong Kun Lee, Yeonhee Ryu, Eun Sang Cho. Activation of Protein Kinase G After Repeated Cocaine Administration Is Necessary for the Phosphorylation of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor GluA1 at Serine 831 in the Rat Nucleus Accumbens. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30104957. the present study determined if activation of protein kinase g (pkg) contributes to the phosphorylation of ampa receptor glua1 subunit at the position of serine 831 (glua1-s831) in the rat nucleus accumbens (nac) after repeated cocaine administration. 2020-09-30 2023-08-13 rat
Anze Testen, Marian T Sepulveda-Orengo, Christiann H Gaines, Kathryn J Reissne. Region-Specific Reductions in Morphometric Properties and Synaptic Colocalization of Astrocytes Following Cocaine Self-Administration and Extinction. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30147645. we recently showed that astrocytes within the nucleus accumbens (nac) core exhibit decreased volume, surface area, and synaptic colocalization following cocaine self-administration and extinction, compared to nac astrocytes from saline-administering animals (scofield et al., 2016b). 2020-09-30 2023-08-13 rat
Taylor P LaRese, Bruce A Rheaume, Ron Abraham, Betty A Eipper, Richard E Main. Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure. Journal of the Endocrine Society. vol 3. issue 2. 2020-09-30. PMID:30746506. sex-specific gene expression in the mouse nucleus accumbens before and after cocaine exposure. 2020-09-30 2023-08-13 mouse
Taylor P LaRese, Bruce A Rheaume, Ron Abraham, Betty A Eipper, Richard E Main. Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure. Journal of the Endocrine Society. vol 3. issue 2. 2020-09-30. PMID:30746506. the nucleus accumbens plays a major role in the response of mammals to cocaine. 2020-09-30 2023-08-13 mouse
Taylor P LaRese, Bruce A Rheaume, Ron Abraham, Betty A Eipper, Richard E Main. Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure. Journal of the Endocrine Society. vol 3. issue 2. 2020-09-30. PMID:30746506. nucleus accumbens transcripts differentially expressed in cycling female mice withdrawn from cocaine exhibited substantial overlap with those differentially expressed in cocaine-withdrawn male mice. 2020-09-30 2023-08-13 mouse
Suchan Chang, Yeonhee Ryu, Yu Fan, Se Kyun Bang, Nam Jun Kim, Jin Gyeom Lee, Jin Mook Kim, Bong Hyo Lee, Chae Ha Yang, Hee Young Ki. Involvement of the Cuneate Nucleus in the Acupuncture Inhibition of Drug-Seeking Behaviors. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31555084. our previous studies have shown that acupuncture suppresses addictive behaviors induced by drugs of abuse, including cocaine, morphine and ethanol, by modulating gaba neurons in the ventral tegmental area (vta) and dopamine (da) release in the nucleus accumbens (nac). 2020-09-30 2023-08-13 Not clear
Kenneth Blum, Rajendra D Badgaiyan, Eric R Braverman, Kristina Dushaj, Mona Li, Peter K Thanos, Zsolt Demetrovics, Marcelo Feb. Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term. Journal of reward deficiency syndrome and addiction science. vol 2. issue 1. 2020-09-29. PMID:28317038. it is also well accepted that psychostimulants such as cocaine affect not only the release of neuronal dopamine at the nucleus accumbens (nac), but also has powerful inhibitory actions on the dopamine transporter system. 2020-09-29 2023-08-13 Not clear
ChengPeng Yu, XiaoYan Zhou, Qiang Fu, QingHua Peng, Ki-Wan Oh, ZhenZhen H. A New Insight into the Role of CART in Cocaine Reward: Involvement of CaMKII and Inhibitory G-Protein Coupled Receptor Signaling. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:28860971. cocaine- and amphetamine-regulated transcript (cart) peptides are neuropeptides that are expressed in brain regions associated with reward, such as the nucleus accumbens (nac), and play a role in cocaine reward. 2020-09-29 2023-08-13 Not clear
Rachel Jarvis, Alessandra Tamashiro-Orrego, Vanessa Promes, Leona Tu, Jinyuan Shi, Yongjie Yan. Cocaine Self-administration and Extinction Inversely Alter Neuron to Glia Exosomal Dynamics in the Nucleus Accumbens. Frontiers in cellular neuroscience. vol 13. 2020-09-29. PMID:31998080. cocaine self-administration and extinction inversely alter neuron to glia exosomal dynamics in the nucleus accumbens. 2020-09-29 2023-08-13 Not clear
Ilse Delint-Ramirez, Amir Segev, Asha Pavuluri, David W Self, Saïd Kourric. Cocaine-Induced Synaptic Redistribution of NMDARs in Striatal Neurons Alters NMDAR-Dependent Signal Transduction. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32760242. the consequence of repeated cocaine exposure and prolonged abstinence on glutamate receptor expression in the nucleus accumbens has been extensively studied. 2020-09-28 2023-08-13 Not clear
Katie E Yoest, Jennifer A Cummings, Jill B Becke. Oestradiol influences on dopamine release from the nucleus accumbens shell: sex differences and the role of selective oestradiol receptor subtypes. British journal of pharmacology. vol 176. issue 21. 2020-09-21. PMID:30381823. in this study, we tested the acute effect of oestradiol on dopamine release in the nucleus accumbens (nac) shell after cocaine administration and investigated which oestradiol receptors (ers) contribute to sex differences in the response to cocaine. 2020-09-21 2023-08-13 Not clear
José Pedro Prieto, Betina González, Javier Muñiz, Verónica Bisagno, Cecilia Scorz. Molecular changes in the nucleus accumbens and prefrontal cortex associated with the locomotor sensitization induced by coca paste seized samples. Psychopharmacology. vol 237. issue 5. 2020-09-15. PMID:32034449. while the cocaine phenomenon is associated with persistent functional and structural alterations in the prefrontal cortex (pfc) and nucleus accumbens (nac), the molecular mechanisms underlying the cp sensitization and the influence of caffeine remains still unknown. 2020-09-15 2023-08-13 rat
In-Jee You, Sa-Ik Hong, Shi-Xun Ma, Thi-Lien Nguyen, Seung-Hwan Kwon, Seok-Yong Lee, Choon-Gon Jan. Transient receptor potential vanilloid 1 mediates cocaine reinstatement via the D1 dopamine receptor in the nucleus accumbens. Journal of psychopharmacology (Oxford, England). vol 33. issue 12. 2020-08-14. PMID:31432769. transient receptor potential vanilloid 1 mediates cocaine reinstatement via the d1 dopamine receptor in the nucleus accumbens. 2020-08-14 2023-08-13 mouse
Constanza Garcia-Keller, Daniela Neuhofer, Ana-Clara Bobadilla, Sade Spencer, Vivian C Chioma, Cara Monforton, Peter W Kaliva. Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-Induced Transient Synaptic Plasticity and Relapse. Biological psychiatry. vol 86. issue 5. 2020-08-13. PMID:31126696. cue-induced transient excitatory synaptic potentiation (t-sp) induced in the nucleus accumbens mediates cued cocaine seeking in rat models of relapse. 2020-08-13 2023-08-13 rat
Constanza Garcia-Keller, Daniela Neuhofer, Ana-Clara Bobadilla, Sade Spencer, Vivian C Chioma, Cara Monforton, Peter W Kaliva. Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-Induced Transient Synaptic Plasticity and Relapse. Biological psychiatry. vol 86. issue 5. 2020-08-13. PMID:31126696. cue-induced t-sp depends on extracellular signaling by matrix metalloproteases (mmps), but it is unknown how this catalytic activity communicates with nucleus accumbens neurons to induce t-sp and cocaine seeking. 2020-08-13 2023-08-13 rat
Alex B Kawa, Alec C Valenta, Robert T Kennedy, Terry E Robinso. Incentive and dopamine sensitization produced by intermittent but not long access cocaine self-administration. The European journal of neuroscience. vol 50. issue 4. 2020-08-11. PMID:30968487. to further address this issue, we compared the effects of long access (lga) cocaine self-administration, which is widely used to model the transition to addiction, with intermittent access (inta), which is thought to better reflect the pattern of drug use in humans, on the ability of a single, self-administered injection of cocaine to increase dopamine (da) overflow in the core of the nucleus accumbens (using in vivo microdialysis), and to produce addiction-like behavior. 2020-08-11 2023-08-13 rat
Alex B Kawa, Alec C Valenta, Robert T Kennedy, Terry E Robinso. Incentive and dopamine sensitization produced by intermittent but not long access cocaine self-administration. The European journal of neuroscience. vol 50. issue 4. 2020-08-11. PMID:30968487. there were no group differences in basal levels of da in dialysate [da], but a single self-administered iv injection of cocaine increased [da] in the core of the nucleus accumbens to a greater extent in rats with prior inta experience than those with lga or limited access experience, and the latter two groups did not differ. 2020-08-11 2023-08-13 rat
Cody A Siciliano, Madelyn I Mauterer, Steve C Fordahl, Sara R Jone. Modulation of striatal dopamine dynamics by cocaine self-administration and amphetamine treatment in female rats. The European journal of neuroscience. vol 50. issue 4. 2020-08-11. PMID:31111573. although it has been suggested that amphetamine treatment reduces cocaine intake as an agonist replacement therapy, we have shown recently that multiple aspects of dopamine signaling are altered by cocaine self-administration and returned to pre-cocaine function by amphetamine treatment in the nucleus accumbens of male rats. 2020-08-11 2023-08-13 human