| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, Eric Kandel, Joel D Richte. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 34. 2008-09-16. PMID:18716208. |
to identify cpeb-1-regulated mrnas, we used proteomics to compare polypeptides in wild-type (wt) and cpeb-1 ko hippocampus. |
2008-09-16 |
2023-08-12 |
mouse |
| N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, Eric Kandel, Joel D Richte. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 34. 2008-09-16. PMID:18716208. |
growth hormone (gh) was reduced in the ko hippocampus, as were the gh signaling molecules phospho-jak2 and phospho-stat3. |
2008-09-16 |
2023-08-12 |
mouse |
| N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, Eric Kandel, Joel D Richte. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 34. 2008-09-16. PMID:18716208. |
gh mrna and pre-mrna were reduced in the ko hippocampus, suggesting that cpeb-1 controls gh transcription. |
2008-09-16 |
2023-08-12 |
mouse |
| N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, Eric Kandel, Joel D Richte. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 34. 2008-09-16. PMID:18716208. |
the transcription factor c-jun, which binds the gh promoter, was also reduced in the ko hippocampus, as was its ability to coimmunoprecipitate chromatin containing the gh promoter. |
2008-09-16 |
2023-08-12 |
mouse |
| N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, Eric Kandel, Joel D Richte. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 34. 2008-09-16. PMID:18716208. |
gh induces long-term potentiation (ltp) when applied to hippocampal slices from wt and cpeb-1 ko mice, but the magnitude of ltp induced by gh in ko mice is reduced. |
2008-09-16 |
2023-08-12 |
mouse |
| N Ruth Zearfoss, Juan Marcos Alarcon, Pierre Trifilieff, Eric Kandel, Joel D Richte. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 34. 2008-09-16. PMID:18716208. |
finally, gh application to hippocampal slices induced jak2 phosphorylation in wt but not ko animals. |
2008-09-16 |
2023-08-12 |
mouse |
| Marika Nosten-Bertrand, Caroline Kappeler, Céline Dinocourt, Cécile Denis, Johanne Germain, Françoise Phan Dinh Tuy, Soraya Verstraeten, Chantal Alvarez, Christine Métin, Jamel Chelly, Bruno Giros, Richard Miles, Antoine Depaulis, Fiona Franci. Epilepsy in Dcx knockout mice associated with discrete lamination defects and enhanced excitability in the hippocampus. PloS one. vol 3. issue 6. 2008-08-20. PMID:18575605. |
dcx knockout (ko) mice show no major isocortical abnormalities, but have discrete hippocampal defects. |
2008-08-20 |
2023-08-12 |
mouse |
| Marika Nosten-Bertrand, Caroline Kappeler, Céline Dinocourt, Cécile Denis, Johanne Germain, Françoise Phan Dinh Tuy, Soraya Verstraeten, Chantal Alvarez, Christine Métin, Jamel Chelly, Bruno Giros, Richard Miles, Antoine Depaulis, Fiona Franci. Epilepsy in Dcx knockout mice associated with discrete lamination defects and enhanced excitability in the hippocampus. PloS one. vol 3. issue 6. 2008-08-20. PMID:18575605. |
we show that the dysplastic ca3 region in ko hippocampal slices generates sharp wave-like activities and possesses a lower threshold for epileptiform events. |
2008-08-20 |
2023-08-12 |
mouse |
| Marika Nosten-Bertrand, Caroline Kappeler, Céline Dinocourt, Cécile Denis, Johanne Germain, Françoise Phan Dinh Tuy, Soraya Verstraeten, Chantal Alvarez, Christine Métin, Jamel Chelly, Bruno Giros, Richard Miles, Antoine Depaulis, Fiona Franci. Epilepsy in Dcx knockout mice associated with discrete lamination defects and enhanced excitability in the hippocampus. PloS one. vol 3. issue 6. 2008-08-20. PMID:18575605. |
in conclusion, seizures in dcx ko mice are likely to be due to abnormal synaptic transmission involving heterotopic cells in the hippocampus and these mice may therefore provide a useful model to further study how lamination defects underlie the genesis of epileptiform activities. |
2008-08-20 |
2023-08-12 |
mouse |
| Long-Jun Wu, Ming Ren, Hansen Wang, Susan S Kim, Xiaoyan Cao, Min Zhu. Neurabin contributes to hippocampal long-term potentiation and contextual fear memory. PloS one. vol 3. issue 1. 2008-08-08. PMID:18183288. |
using neurabin knockout (ko) mice, here we studied the function of neurabin in hippocampal synaptic transmission, plasticity and behavioral memory. |
2008-08-08 |
2023-08-12 |
mouse |
| Lesley M Foley, T Kevin Hitchens, John A Melick, Hülya Bayir, Chien Ho, Patrick M Kochane. Effect of inducible nitric oxide synthase on cerebral blood flow after experimental traumatic brain injury in mice. Journal of neurotrauma. vol 25. issue 4. 2008-07-10. PMID:18373480. |
regional assessment of cbf at 72 h after injury demonstrated that recovery of cbf was reduced in the ipsilateral hippocampus, thalamus, and amygdala/piriform cortex in inos ko versus wt mice by 26%, 15%, and 21%, respectively; this attenuated recovery was restricted to structures outside the contusion. |
2008-07-10 |
2023-08-12 |
mouse |
| Luisa Lo Iacono, Cornelius Gros. Alpha-Ca2+/calmodulin-dependent protein kinase II contributes to the developmental programming of anxiety in serotonin receptor 1A knock-out mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 24. 2008-07-10. PMID:18550767. |
furthermore, we identify increases in the phosphorylation of alpha-ca(2+)/calmodulin-dependent protein kinase ii (alphacamkii) at threonine 286 in the hippocampus of young htr1a(ko) mice under anxiety-provoking conditions. |
2008-07-10 |
2023-08-12 |
mouse |
| Hai-Ying Shen, Joana E Coelho, Nobuhisa Ohtsuka, Paula M Canas, Yuan-Ji Day, Qing-Yuan Huang, Nelson Rebola, Liqun Yu, Detlev Boison, Rodrigo A Cunha, Joel Linden, Joe Z Tsien, Jiang-Fan Che. A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 12. 2008-04-25. PMID:18354001. |
in contrast to fb-a(2a)r ko (deleting a(2a)rs in the neurons of striatum as well as cerebral cortex and hippocampus), st-a(2a)r ko mice exhibited cre-mediated selective deletion of the a(2a)r gene, mrna, and proteins in the neurons (but not astrocytes and microglial cells) of the striatum only. |
2008-04-25 |
2023-08-12 |
mouse |
| C Petit-Turcotte, N Aumont, J-F Blain, J Poirie. Apolipoprotein E receptors and amyloid expression are modulated in an apolipoprotein E-dependent fashion in response to hippocampal deafferentation in rodent. Neuroscience. vol 150. issue 1. 2008-03-28. PMID:17935896. |
the expression of the apolipoprotein e receptor type 2 (apoer2) is also modulated by the deafferentation process in the hippocampus, but only in apoe ko mice. |
2008-03-28 |
2023-08-12 |
mouse |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
in the present paper, we evaluated the role of a(2a)rs in mediating functional effects of bdnf in hippocampus using a(2a)r knock-out (ko) mice. |
2008-02-18 |
2023-08-12 |
mouse |
| M T Tebano, A Martire, R L Potenza, C Grò, R Pepponi, M Armida, M R Domenici, M A Schwarzschild, J F Chen, P Popol. Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. Journal of neurochemistry. vol 104. issue 1. 2008-02-18. PMID:18005343. |
similarly, genetic deletion of the a(2a)rs abolished bdnf-induced increase of the fepsp slope in slices from a(2a)r ko mice the reduced functional ability of bdnf in a(2a)r ko mice was correlated with the reduction in hippocampal bdnf levels. |
2008-02-18 |
2023-08-12 |
mouse |
| Stéphanie Weiss, Marika Nosten-Bertrand, J Michael McIntosh, Bruno Giros, Marie-Pascale Martre. Nicotine improves cognitive deficits of dopamine transporter knockout mice without long-term tolerance. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 12. 2008-02-14. PMID:17375139. |
we speculate that the procognitive effects of nicotine in dat ko mice are related to the upregulation of alpha7 nicotinic receptors in the hippocampus, amygdala, and prelimbic cortex, all areas involved in cognition. |
2008-02-14 |
2023-08-12 |
mouse |
| Yann Senechal, Peter H Kelly, Kumlesh K De. Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning. Behavioural brain research. vol 186. issue 1. 2008-02-12. PMID:17884188. |
the absence of app expression in app ko mice was confirmed at the protein level using hippocampal tissue in western blotting. |
2008-02-12 |
2023-08-12 |
mouse |
| Virginie Biou, Samarjit Bhattacharyya, Robert C Malenk. Endocytosis and recycling of AMPA receptors lacking GluR2/3. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 3. 2008-02-12. PMID:18195348. |
here, we address the roles of glur2 and glur3 in controlling the recycling- and activity-dependent endocytosis of ampars by using cultured hippocampal neurons prepared from knockout (ko) mice lacking these subunits. |
2008-02-12 |
2023-08-12 |
mouse |
| T Takasusuki, T Fujiwara, S Yamaguchi, T Fukushima, K Akagawa, Y Hor. Enhancement of synaptic transmission and nociceptive behaviour in HPC-1/syntaxin 1A knockout mice following peripheral nerve injury. The European journal of neuroscience. vol 26. issue 8. 2008-02-01. PMID:17953616. |
our previous analysis of hpc-1/syntaxin 1a knockout (ko) mice indicated that hpc-1/syntaxin 1a plays an important role in the synaptic plasticity of the hippocampus in vitro and learning behaviour in vivo. |
2008-02-01 |
2023-08-12 |
mouse |