| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Fullerton, G A Shirman, W J Strittmatter, W D Matthe. Impairment of the blood-nerve and blood-brain barriers in apolipoprotein e knockout mice. Experimental neurology. vol 169. issue 1. 2001-06-07. PMID:11312553. |
in a subpopulation of apoe ko mice, igg also extravasates into discrete cortical and subcortical locations, including hippocampus. |
2001-06-07 |
2023-08-12 |
mouse |
| Z Sarnyai, E L Sibille, C Pavlides, R J Fenster, B S McEwen, M Tot. Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 26. 2001-02-15. PMID:11121072. |
to test whether a deficit in 5-ht(1a) receptors impairs hippocampus-related functions, we studied hippocampal-dependent learning and memory, synaptic plasticity in the hippocampus, and limbic neuronal excitability in 5-ht(1a)-knockout (ko) mice. |
2001-02-15 |
2023-08-12 |
mouse |
| K Braun, M Sega. FMRP involvement in formation of synapses among cultured hippocampal neurons. Cerebral cortex (New York, N.Y. : 1991). vol 10. issue 10. 2000-10-25. PMID:11007555. |
hippocampal neurons taken from ko mice and grown in culture for 3 weeks have shorter dendrites and fewer dendritic spines than their wt counterparts. |
2000-10-25 |
2023-08-12 |
mouse |
| M L Schaefer, S T Wong, D F Wozniak, L M Muglia, J A Liauw, M Zhuo, A Nardi, R E Hartman, S K Vogt, C E Luedke, D R Storm, L J Mugli. Altered stress-induced anxiety in adenylyl cyclase type VIII-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 13. 2000-07-26. PMID:10864938. |
ac8 ko mice demonstrate a compromise in calcium-stimulated ac activity in the hippocampus, hypothalamus, thalamus, and brainstem. |
2000-07-26 |
2023-08-12 |
mouse |
| M L Schaefer, S T Wong, D F Wozniak, L M Muglia, J A Liauw, M Zhuo, A Nardi, R E Hartman, S K Vogt, C E Luedke, D R Storm, L J Mugli. Altered stress-induced anxiety in adenylyl cyclase type VIII-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 13. 2000-07-26. PMID:10864938. |
hippocampal slices derived from ac8 ko mice fail to demonstrate ca1-region long-term depression after low-frequency stimulation, and ac8 ko mice also fail to activate cre-binding protein in the ca1 region after restraint stress. |
2000-07-26 |
2023-08-12 |
mouse |
| A U Trendelenburg, L Hein, E G Gaiser, K Stark. Occurrence, pharmacology and function of presynaptic alpha2-autoreceptors in alpha2A/D-adrenoceptor-deficient mice. Naunyn-Schmiedeberg's archives of pharmacology. vol 360. issue 5. 2000-02-07. PMID:10598793. |
the occurrence, pharmacological properties and function of alpha2-autoreceptors were studied in hippocampal slices, occipito-parietal cortex slices, segments of heart atria and segments of the vas deferens of wildtype (wt) mice and mice in which the alpha2 a/d-adrenoceptor gene had been disrupted (alpha2 a/d(ko)). |
2000-02-07 |
2023-08-12 |
mouse |
| A C Trillat, I Malagié, M Bourin, C Jacquot, R Hen, A M Gardie. [Homozygote mice deficient in serotonin 5-HT1B receptor and antidepressant effect of selective serotonin reuptake inhibitors]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 192. issue 6. 1999-05-03. PMID:10101609. |
using microdialysis in awake 129/sv mice, we show that the absence of the 5-ht1b receptor in mutant mice (ko 1b -/-) potentiated the effect of paroxetine on extracellular 5-ht levels in the ventral hippocampus, but not in the frontal cortex compared to wild-type mice (wt). |
1999-05-03 |
2023-08-12 |
mouse |
| R Anderson, G A Higgin. Absence of central cholinergic deficits in ApoE knockout mice. Psychopharmacology. vol 132. issue 2. 1997-10-20. PMID:9266610. |
in addition, coronal sections of striatum and anterior hippocampal regions of apoe ko and wild type mice showed similar patterns of acetylcholinesterase (ache) staining, with no qualitative or obvious quantitative difference. |
1997-10-20 |
2023-08-12 |
mouse |