| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ning Song, Shin Nakagawa, Takeshi Izumi, Hiroyuki Toda, Akiko Kato, Shuken Boku, Takeshi Inoue, Hiroyuki Sakagami, Xiaobai Li, Tsukasa Koyam. Involvement of CaMKIV in neurogenic effect with chronic fluoxetine treatment. The international journal of neuropsychopharmacology. vol 16. issue 4. 2013-12-27. PMID:22695008. |
effects of chronic flx on hippocampal cell proliferation, survival and phenotypes were assessed using bromodeoxyuridine (brdu) immunohistochemistry or brdu/neuronal nuclei (neun)/s100β immunofluorescence staining in wild-type (wt) and camkiv knockout (ko) mice. |
2013-12-27 |
2023-08-12 |
mouse |
| Ning Song, Shin Nakagawa, Takeshi Izumi, Hiroyuki Toda, Akiko Kato, Shuken Boku, Takeshi Inoue, Hiroyuki Sakagami, Xiaobai Li, Tsukasa Koyam. Involvement of CaMKIV in neurogenic effect with chronic fluoxetine treatment. The international journal of neuropsychopharmacology. vol 16. issue 4. 2013-12-27. PMID:22695008. |
camkiv ko mice have reduced cell proliferation, but not survival in the dentate gyrus of hippocampus with chronic treatment of flx when compared to wild littermates. |
2013-12-27 |
2023-08-12 |
mouse |
| Jacob Raber, Antiño R Allen, Susanna Rosi, Sourabh Sharma, Catherine Dayger, Matthew J Davis, John R Fik. Effects of (56)Fe radiation on hippocampal function in mice deficient in chemokine receptor 2 (CCR2). Behavioural brain research. vol 246. 2013-10-28. PMID:23500678. |
ccr2 ko and wild-type mice were used to compare effects of (56)fe radiation (600mev, 0.25gy) on hippocampal function using contextual fear conditioning involving tone shock pairing during training (+/+) and exposure to the same environment without tone shock pairings (-/-). |
2013-10-28 |
2023-08-12 |
mouse |
| Fernando Kreutz, Fernanda dos Santos Petry, Melissa Camassola, Vanessa Schein, Fátima C R Guma, Nance Beyer Nardi, Vera Maria Treis Trindad. Alterations of membrane lipids and in gene expression of ganglioside metabolism in different brain structures in a mouse model of mucopolysaccharidosis type I (MPS I). Gene. vol 527. issue 1. 2013-10-22. PMID:23774686. |
this study is aimed to evaluate the levels and distribution of gangliosides and cholesterol in different brain regions (cortex, cerebellum, hippocampus and hypothalamus) in a model using idua knockout (ko) mice (c57bl/6). |
2013-10-22 |
2023-08-12 |
mouse |
| Fernando Kreutz, Fernanda dos Santos Petry, Melissa Camassola, Vanessa Schein, Fátima C R Guma, Nance Beyer Nardi, Vera Maria Treis Trindad. Alterations of membrane lipids and in gene expression of ganglioside metabolism in different brain structures in a mouse model of mucopolysaccharidosis type I (MPS I). Gene. vol 527. issue 1. 2013-10-22. PMID:23774686. |
while no changes in cholesterol content were observed, the results showed a tissue dependent ganglioside alteration in ko mice: a total ganglioside increase in cortex and cerebellum, and a selective presence of gm3, gm2 and gd3 gangliosides in the hippocampus and hypothalamus. |
2013-10-22 |
2023-08-12 |
mouse |
| Fernando Kreutz, Fernanda dos Santos Petry, Melissa Camassola, Vanessa Schein, Fátima C R Guma, Nance Beyer Nardi, Vera Maria Treis Trindad. Alterations of membrane lipids and in gene expression of ganglioside metabolism in different brain structures in a mouse model of mucopolysaccharidosis type I (MPS I). Gene. vol 527. issue 1. 2013-10-22. PMID:23774686. |
the results obtained with ko mice showed a reduced expression of gd3 and gm2/gd2 synthases and neuraminidase1 in cerebellum; and a decrease in gm2/gd2 synthase and neuraminidase1 in the hippocampus. |
2013-10-22 |
2023-08-12 |
mouse |
| Roopali Yadav, Brandon G Hillman, Subhash C Gupta, Pratyush Suryavanshi, Jay M Bhatt, Ratnamala Pavuluri, Dustin J Stairs, Shashank M Dravi. Deletion of glutamate delta-1 receptor in mouse leads to enhanced working memory and deficit in fear conditioning. PloS one. vol 8. issue 4. 2013-09-16. PMID:23560106. |
we further studied molecular changes in the hippocampus, where we found lower levels of glua1, glua2 and gluk2 subunits while a contrasting higher level of glun2b in glud1 ko. |
2013-09-16 |
2023-08-12 |
mouse |
| Rebecca E Horton, Deana M Apple, W Anthony Owens, Nicole L Baganz, Sonia Cano, Nathan C Mitchell, Melissa Vitela, Georgianna G Gould, Wouter Koek, Lynette C Daw. Decynium-22 enhances SSRI-induced antidepressant-like effects in mice: uncovering novel targets to treat depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 25. 2013-08-30. PMID:23785165. |
this antidepressant-like activity of d-22 was attenuated in oct3 ko mice, whereas the effect of d-22 to inhibit 5-ht clearance in the ca3 region of hippocampus persisted. |
2013-08-30 |
2023-08-12 |
mouse |
| David J Koss, Gernot Riedel, Kendra Bence, Bettina Plat. Store-operated Ca2+ entry in hippocampal neurons: Regulation by protein tyrosine phosphatase PTP1B. Cell calcium. vol 53. issue 2. 2013-08-15. PMID:23218930. |
cyclopiazonic acid induced soce was characterised in hippocampal cultures derived from forebrain specific protein tyrosine phosphatase 1b knockout (ptp1b ko) mice and wild type (wt) litter mates using fura-2 ca(2+) imaging. |
2013-08-15 |
2023-08-12 |
mouse |
| Jing Tong, Weimin Liu, Xiaowei Wang, Xiaodi Han, Ollivier Hyrien, Uzma Samadani, Douglas H Smith, Jason H Huan. Inhibition of Nogo-66 receptor 1 enhances recovery of cognitive function after traumatic brain injury in mice. Journal of neurotrauma. vol 30. issue 4. 2013-08-12. PMID:22967270. |
increased transcription of growth-associated protein (gap)-43 in both the injured and contralateral sides of the hippocampus (both p<0.05) was detected in ngr1 ko mice relative to wt. |
2013-08-12 |
2023-08-12 |
mouse |
| Anja Urbach, Ita Robakiewicz, Eileen Baum, Leszek Kaczmarek, Otto W Witte, Robert K Filipkowsk. Cyclin D2 knockout mice with depleted adult neurogenesis learn Barnes maze task. Behavioral neuroscience. vol 127. issue 1. 2013-07-26. PMID:23244288. |
in this work, however, we demonstrate adult cyclin d2 knockout (cd2 ko) mice, which lack adult hippocampal neurogenesis, are able to learn a spatial version of the barnes maze. |
2013-07-26 |
2023-08-12 |
mouse |
| Joseph E Pick, Li Wang, Joshua E Mayfield, Eric Klan. Neuronal expression of the ubiquitin E3 ligase APC/C-Cdh1 during development is required for long-term potentiation, behavioral flexibility, and extinction. Neurobiology of learning and memory. vol 100. 2013-07-23. PMID:23238556. |
although we detected impaired long-term potentiation (ltp) in hippocampal slices from the nse-cdh1 knockout (ko) mice, performance on several hippocampus-dependent memory tasks remained intact. |
2013-07-23 |
2023-08-12 |
mouse |
| Helen S Bateup, Caroline A Johnson, Cassandra L Denefrio, Jessica L Saulnier, Karl Kornacker, Bernardo L Sabatin. Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis. Neuron. vol 78. issue 3. 2013-07-09. PMID:23664616. |
in tsc1 ko neurons, weakened inhibition caused by deregulated mtor alters the balance of excitatory and inhibitory synaptic transmission, leading to hippocampal hyperexcitability. |
2013-07-09 |
2023-08-12 |
mouse |
| Alessandra Berry, Irmgard Amrein, Sarah Nötzli, Stan E Lazic, Veronica Bellisario, Marco Giorgio, Pier Giuseppe Pelicci, Enrico Alleva, Hans-Peter Lipp, Francesca Cirull. Sustained hippocampal neurogenesis in females is amplified in P66(Shc-/-) mice: An animal model of healthy aging. Hippocampus. vol 22. issue 12. 2013-06-27. PMID:22707391. |
to this aim, granule cell number, proliferation, neuronal differentiation, and cell death were assessed in the hippocampus in senescent p66(shc-/-) [knock out (ko)] and p66(shc+/+) [wild type (wt)] male and female mice. |
2013-06-27 |
2023-08-12 |
mouse |
| Charlotte M Wincott, Seonil Kim, Roseann F Titcombe, David S Tukey, Hiwot K Girma, Joseph E Pick, Loren M Devito, Franz Hofmann, Charles Hoeffer, Edward B Zif. Spatial memory deficits and motor coordination facilitation in cGMP-dependent protein kinase type II-deficient mice. Neurobiology of learning and memory. vol 99. 2013-06-17. PMID:23103773. |
we also show diminished glua1 phosphorylation in the postsynaptic density (psd) of cgkii ko prefrontal cortex while in hippocampal psd fractions, phosphorylation was not significantly altered. |
2013-06-17 |
2023-08-12 |
mouse |
| Osama Mohamad, Mingke Song, Ling Wei, Shan Ping Y. Regulatory roles of the NMDA receptor GluN3A subunit in locomotion, pain perception and cognitive functions in adult mice. The Journal of physiology. vol 591. issue 1. 2013-06-13. PMID:23006484. |
hippocampal slices from juvenile and adult glun3a ko mice showed greater long-term potentiation (ltp) compared with wt slices. |
2013-06-13 |
2023-08-12 |
mouse |
| Osama Mohamad, Mingke Song, Ling Wei, Shan Ping Y. Regulatory roles of the NMDA receptor GluN3A subunit in locomotion, pain perception and cognitive functions in adult mice. The Journal of physiology. vol 591. issue 1. 2013-06-13. PMID:23006484. |
glun3a deletion resulted in increased expression of ca(2+)/calmodulin-dependent kinase ii (camkii) in the forebrain, and the phosphorylated camkii level upon ltp induction was significantly higher in the glun3a ko hippocampus compared with wt controls. |
2013-06-13 |
2023-08-12 |
mouse |
| Eszter Paldy, Erika Borcel, Alejandro Higuera-Matas, Gonzalo López-Montoya, Tibor Wenger, Geza Toth, Anna Borsodi, Emilio Ambrosi. CNR1 gene deletion affects the density of endomorphin-2 binding sites in the mouse brain in a hemisphere-specific manner. European journal of pharmacology. vol 698. issue 1-3. 2013-06-10. PMID:23142371. |
while, the density of em-2 binding sites in cb(1)r ko mice was higher in the ca3 hippocampal field and in the pontine tegmental nuclei, it was lower in the superior colliculus and ventral tegmental area than in wt controls. |
2013-06-10 |
2023-08-12 |
mouse |
| Kuo-Ching Wang, Yih-Jing Lee, Lir-Wan Fan, Pao-Pao Yang, Pao-Luh Tao, Ing-Kang Ho, Lu-Tai Tie. Mu-opioid receptor knockout mice are more sensitive to chlordiazepoxide-induced anxiolytic behavior. Brain research bulletin. vol 90. 2013-05-30. PMID:23142328. |
we have previously demonstrated benzodiazepine binding in the cortex and hippocampus of mu-opioid receptor knockout (ko) mice. |
2013-05-30 |
2023-08-12 |
mouse |
| Kevin D Phelan, U Thaung Shwe, Joel Abramowitz, Hong Wu, Sung W Rhee, Matthew D Howell, Paul E Gottschall, Marc Freichel, Veit Flockerzi, Lutz Birnbaumer, Fang Zhen. Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms. Molecular pharmacology. vol 83. issue 2. 2013-05-30. PMID:23188715. |
here, we report that trpc5 knockout (ko) mice exhibit both significantly reduced seizures and minimal seizure-induced neuronal cell death in the hippocampus. |
2013-05-30 |
2023-08-12 |
mouse |