| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fei Zheng, Ming Zhang, Qi Ding, Ferzin Sethna, Lily Yan, Changjong Moon, Miyoung Yang, Hongbing Wan. Voluntary running depreciates the requirement of Ca2+-stimulated cAMP signaling in synaptic potentiation and memory formation. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 8. 2018-01-16. PMID:27421897. |
running up-regulated exon ii mrna level of bdnf (brain-derived neurotrophic factor), though it failed to increase exon i and iv mrnas in the hippocampus of ac1 ko mice. |
2018-01-16 |
2023-08-13 |
mouse |
| Lin-Tao Zhou, Shun-Hua Ye, Hai-Xuan Yang, Yong-Ting Zhou, Qi-Hua Zhao, Wei-Wen Sun, Mei-Mei Gao, Yong-Hong Yi, Yue-Sheng Lon. A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14. Neuroscience. vol 349. 2018-01-16. PMID:28257890. |
we show that the relative skipping/inclusion ratio of the micro-exon l in the protrudin gene and exon 10 in the tau gene decreased in the hippocampus of fmr1 knockout (ko) mice. |
2018-01-16 |
2023-08-13 |
mouse |
| Celia González-Castillo, Daniel Ortuño-Sahagún, Carolina Guzmán-Brambila, Ana Laura Márquez-Aguirre, Rita Raisman-Vozari, Mercé Pallás, Argelia E Rojas-Mayorquí. The absence of pleiotrophin modulates gene expression in the hippocampus in vivo and in cerebellar granule cells in vitro. Molecular and cellular neurosciences. vol 75. 2018-01-12. PMID:27468976. |
the microarray analysis identified 102 genes that are differentially expressed (z-score>3.0) in ptn null mice, and the expression of eight of those modified in the hippocampus of ko mice was also modified in vitro after silencing ptn in cultured neurons with sirnas. |
2018-01-12 |
2023-08-13 |
mouse |
| Pavel I Zimin, Christian B Woods, Albert Quintana, Jan-Marino Ramirez, Philip G Morgan, Margaret M Sedensk. Glutamatergic Neurotransmission Links Sensitivity to Volatile Anesthetics with Mitochondrial Function. Current biology : CB. vol 26. issue 16. 2017-12-27. PMID:27498564. |
the effects of isoflurane were similar on evoked field excitatory postsynaptic potentials (fepsps) and paired pulse facilitation (ppf) in ko and control hippocampal slices. |
2017-12-27 |
2023-08-13 |
mouse |
| Min Wang, Osamu Uchiumi, Hideo Ogiso, Yuan Shui, Jingyu Zou, Chieko Hashizume, Makoto Taniguchi, Toshiro Okazaki, Nobuo Kat. Stressful learning paradigm precludes manifestation of cognitive ability in sphingomyelin synthase-2 knockout mice. Behavioural brain research. vol 319. 2017-12-21. PMID:27840247. |
we examined learning ability and hippocampal synaptic plasticity in mice deficient in sms2 (sms2 ko). |
2017-12-21 |
2023-08-13 |
mouse |
| Min Wang, Osamu Uchiumi, Hideo Ogiso, Yuan Shui, Jingyu Zou, Chieko Hashizume, Makoto Taniguchi, Toshiro Okazaki, Nobuo Kat. Stressful learning paradigm precludes manifestation of cognitive ability in sphingomyelin synthase-2 knockout mice. Behavioural brain research. vol 319. 2017-12-21. PMID:27840247. |
mass spectrometry suggested a slightly altered species distribution of ceramide in the hippocampus of sms2 ko mice. |
2017-12-21 |
2023-08-13 |
mouse |
| Phillip A Geist, Brooke N Dulka, Abigail Barnes, Michael Totty, Subimal Datt. BNDF heterozygosity is associated with memory deficits and alterations in cortical and hippocampal EEG power. Behavioural brain research. vol 332. 2017-12-19. PMID:28576309. |
we found that bdnf ko rats were impaired in novelty recognition and fear memory retention, while hippocampal eeg power was decreased in slow waves and increased in fast waves. |
2017-12-19 |
2023-08-13 |
rat |
| Vanesa Nieto-Estévez, Carlos O Oueslati-Morales, Lingling Li, James Pickel, Aixa V Morales, Carlos Vicario-Abejó. Brain Insulin-Like Growth Factor-I Directs the Transition from Stem Cells to Mature Neurons During Postnatal/Adult Hippocampal Neurogenesis. Stem cells (Dayton, Ohio). vol 34. issue 8. 2017-12-12. PMID:27144663. |
to address the influence of igf-i on the stages of hippocampal neurogenesis, we studied a postnatal/adult global igf-i knockout (ko) mice (igf-i(-/-) ) and a nervous system igf-i conditional ko (igf-i(Δ/Δ) ). |
2017-12-12 |
2023-08-13 |
mouse |
| Vanesa Nieto-Estévez, Carlos O Oueslati-Morales, Lingling Li, James Pickel, Aixa V Morales, Carlos Vicario-Abejó. Brain Insulin-Like Growth Factor-I Directs the Transition from Stem Cells to Mature Neurons During Postnatal/Adult Hippocampal Neurogenesis. Stem cells (Dayton, Ohio). vol 34. issue 8. 2017-12-12. PMID:27144663. |
dividing progenitors were also generated in greater numbers in clonal hippocampal stem cell (hpsc) cultures from the ko mice. |
2017-12-12 |
2023-08-13 |
mouse |
| J R Gomes, R S Nogueira, M Vieira, S D Santos, J P Ferraz-Nogueira, J B Relvas, M J Saraiv. Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia. Cell death and differentiation. vol 23. issue 11. 2017-12-11. PMID:27518433. |
moreover, under excitotoxic conditions, ttr stimulation rescued cell death and neurite loss in ttr ko hippocampal neurons, which are more sensitive to excitotoxic degeneration than wt neurons, in a megalin-dependent manner. |
2017-12-11 |
2023-08-13 |
mouse |
| Tomoyuki Tashiro, Yuki Murakami, Akihiro Mouri, Yukio Imamura, Toshitaka Nabeshima, Yasuko Yamamoto, Kuniaki Sait. Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions. Behavioural brain research. vol 317. 2017-11-29. PMID:27693848. |
we measured contents of trp and monoamines and their metabolites in the serum and hippocampus of kmo ko mice. |
2017-11-29 |
2023-08-13 |
mouse |
| Tomoyuki Tashiro, Yuki Murakami, Akihiro Mouri, Yukio Imamura, Toshitaka Nabeshima, Yasuko Yamamoto, Kuniaki Sait. Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions. Behavioural brain research. vol 317. 2017-11-29. PMID:27693848. |
higher contents of trp metabolites such as kynurenine (kyn), kynurenic acid (ka), anthranilic acid (aa), and 3-hydroxykynurenine (3-hk) in the serum and hippocampus and decreased serotonin turnover and higher content of normetanephrine (nm) in the hippocampus were observed in the kmo ko mice. |
2017-11-29 |
2023-08-13 |
mouse |
| Connie Cheng, Sally K M Lau, Laurie C Doerin. Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model. Molecular brain. vol 9. issue 1. 2017-11-17. PMID:27485117. |
correspondingly, fmr1 ko hippocampal neurons exhibited morphological deficits in dendritic spines and alterations in excitatory synapse formation following long-term culture. |
2017-11-17 |
2023-08-13 |
mouse |
| Yuta Yoshino, Mitsue Ishisaka, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hiroyuki Yoshida, Shintaro Inoue, Masayuki Shimoda, Yasunori Okada, Hideaki Har. Distribution and function of hyaluronan binding protein involved in hyaluronan depolymerization (HYBID, KIAA1199) in the mouse central nervous system. Neuroscience. vol 347. 2017-11-07. PMID:28189611. |
the average molecular mass of hippocampal ha increased in ko mice, accompanied by a significant increase in the total ha amount. |
2017-11-07 |
2023-08-13 |
mouse |
| Ilaria Bertani, Valentina Iori, Massimo Trusel, Mattia Maroso, Claudia Foray, Susanna Mantovani, Raffaella Tonini, Annamaria Vezzani, Roberto Chies. Inhibition of IL-1β Signaling Normalizes NMDA-Dependent Neurotransmission and Reduces Seizure Susceptibility in a Mouse Model of Creutzfeldt-Jakob Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 43. 2017-11-06. PMID:28924012. |
at ∼300 d of age, the magnitude of ltp increased in tg(cjd) mice but decreased in prp ko mice, indicating divergent changes in hippocampal synaptic responsiveness. |
2017-11-06 |
2023-08-13 |
mouse |
| Ilaria Bertani, Valentina Iori, Massimo Trusel, Mattia Maroso, Claudia Foray, Susanna Mantovani, Raffaella Tonini, Annamaria Vezzani, Roberto Chies. Inhibition of IL-1β Signaling Normalizes NMDA-Dependent Neurotransmission and Reduces Seizure Susceptibility in a Mouse Model of Creutzfeldt-Jakob Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 43. 2017-11-06. PMID:28924012. |
tg(cjd) but not prp ko mice were intrinsically more susceptible than wt controls to focal hippocampal seizures induced by kainic acid. |
2017-11-06 |
2023-08-13 |
mouse |
| M Angeles Luque, Pablo Beltran-Matas, M Carmen Marin, Blas Torres, Luis Herrer. Excitability is increased in hippocampal CA1 pyramidal cells of Fmr1 knockout mice. PloS one. vol 12. issue 9. 2017-10-17. PMID:28931075. |
with a view to determining the effects of the absence of fmrp on cell excitability, we studied rheobase, action potential duration, firing frequency-current intensity relationship and action potential after-hyperpolarization (ahp) in ca1 pyramidal cells of the hippocampus of wild type (wt) and fmr1 ko male mice. |
2017-10-17 |
2023-08-13 |
mouse |
| Y Han, R J Heuermann, K A Lyman, D Fisher, Q-A Ismail, D M Chetkovic. HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects. Molecular psychiatry. vol 22. issue 3. 2017-10-02. PMID:27400855. |
we found that restoring trip8b to the hippocampus was sufficient to reverse the impaired hcn-channel trafficking and antidepressant-like behavioral effects caused by trip8b ko. |
2017-10-02 |
2023-08-13 |
mouse |
| Y Han, R J Heuermann, K A Lyman, D Fisher, Q-A Ismail, D M Chetkovic. HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects. Molecular psychiatry. vol 22. issue 3. 2017-10-02. PMID:27400855. |
moreover, we found that hippocampal expression of a mutated version of trip8b further impaired hcn-channel trafficking and increased the antidepressant-like behavioral phenotype of trip8b ko mice. |
2017-10-02 |
2023-08-13 |
mouse |
| Reham Khalaf-Nazzal, Melissa A Stouffer, Robert Olaso, Leila Muresan, Audrey Roumegous, Virginie Lavilla, Wassila Carpentier, Imane Moutkine, Sylvie Dumont, Benoit Albaud, Nicolas Cagnard, Hugues Roest Crollius, Fiona Franci. Early born neurons are abnormally positioned in the doublecortin knockout hippocampus. Human molecular genetics. vol 26. issue 1. 2017-09-26. PMID:28007902. |
dcx ko mice also exhibit spontaneous epileptic activity originating in the hippocampus. |
2017-09-26 |
2023-08-13 |
mouse |