| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marie Fahrenhold, Sonja Rakic, John Classey, Carol Brayne, Paul G Ince, James A R Nicoll, Delphine Boch. TREM2 expression in the human brain: a marker of monocyte recruitment? Brain pathology (Zurich, Switzerland). vol 28. issue 5. 2019-03-05. PMID:28987033. |
as expected, iba1 and cd68 labeled microglia and perivascular macrophages. |
2019-03-05 |
2023-08-13 |
human |
| For Yue Tso, Guobin Kang, Eun Hee Kwon, Peter Julius, Qingsheng Li, John T West, Charles Woo. Brain is a potential sanctuary for subtype C HIV-1 irrespective of ART treatment outcome. PloS one. vol 13. issue 7. 2019-01-28. PMID:30040863. |
when combined with immunohistochemistry, rna/dnascope ish demonstrated co-localization of hiv-1 dna with cd68 expressing cells indicative of microglia or peripheral macrophage. |
2019-01-28 |
2023-08-13 |
Not clear |
| A Trost, C Runge, D Bruckner, A Kaser-Eichberger, B Bogner, C Strohmaier, H A Reitsamer, F Schroed. Lymphatic markers in the human optic nerve. Experimental eye research. vol 173. 2019-01-11. PMID:29746818. |
cross and longitudinal cryo-sections of human optic nerve tissue (n = 12, male and female, postmortem time = 15.8 ± 5.5 h, age = 66.5 ± 13.8 years), were obtained from cornea donors of the salzburg eye bank, and analyzed using immunofluorescence with the following markers: foxc2, ccl21, lyve-1 and podoplanin (pdpn; lymphatic markers), iba1 (microglia), cd68 (macrophages), cd31 (endothelial cell, ec), nf200 (neurofilament), as well as gfap (astrocytes). |
2019-01-11 |
2023-08-13 |
human |
| Murielle G Kluge, Laura Kracht, Mahmoud Abdolhoseini, Lin Kooi Ong, Sarah J Johnson, Michael Nilsson, Frederick R Walke. Impaired microglia process dynamics post-stroke are specific to sites of secondary neurodegeneration. Glia. vol 65. issue 12. 2018-06-05. PMID:28836304. |
however, microglia at both sites displayed an activated morphology and elevated levels of commonly used activation markers (cd68, cd11b), indicating that the standardly used fixed tissue metrics of microglial "activity" are not necessarily predictive of microglia function. |
2018-06-05 |
2023-08-13 |
mouse |
| T Seredenina, S Sorce, F R Herrmann, X-J Ma Mulone, O Plastre, A Aguzzi, V Jaquet, K-H Kraus. Decreased NOX2 expression in the brain of patients with bipolar disorder: association with valproic acid prescription and substance abuse. Translational psychiatry. vol 7. issue 8. 2018-05-08. PMID:28809856. |
immunostaining demonstrated that nox2 was predominantly expressed in microglia, which was corroborated by a decrease in the microglial markers cd68 and cd11b in the cingulate cortex of bipolar disorder patients. |
2018-05-08 |
2023-08-13 |
human |
| b' T Havr\\xc3\\xa1nek, Z Le\\xc5\\xa1\\xc5\\xa5anov\\xc3\\xa1, B Mravec, V \\xc5\\xa0trb\\xc3\\xa1k, J Bako\\xc5\\xa1, Z Ba\\xc4\\x8dov\\xc3\\xa. Oxytocin Modulates Expression of Neuron and Glial Markers in the Rat Hippocampus. Folia biologica. vol 63. issue 3. 2018-05-07. PMID:28805558.' |
oxytocin treatment resulted in a decrease of oligodendrocyte marker mrna - 2',3'-cyclic nucleotide 3'-phosphodiesterase (cnpase) - in 21-day and 2-month old rats, while no change of cd68 mrna, marker of microglia, was observed. |
2018-05-07 |
2023-08-13 |
rat |
| Munjal M Acharya, Kim N Green, Barrett D Allen, Allison R Najafi, Amber Syage, Harutyun Minasyan, Mi T Le, Takumi Kawashita, Erich Giedzinski, Vipan K Parihar, Brian L West, Janet E Baulch, Charles L Limol. Elimination of microglia improves cognitive function following cranial irradiation. Scientific reports. vol 6. 2018-05-02. PMID:27516055. |
animals receiving the plx5622 diet exhibited no radiation-induced cognitive deficits, and exhibited near complete loss of iba-1 and cd68 positive microglia in the mpfc and hippocampus. |
2018-05-02 |
2023-08-13 |
mouse |
| Aida Kiviniemi, Maria Gardberg, Katri Kivinen, Jussi P Posti, Ville Vuorinen, Jussi Sipilä, Melissa Rahi, Matti Sankinen, Heikki Min. Somatostatin receptor 2A in gliomas: Association with oligodendrogliomas and favourable outcome. Oncotarget. vol 8. issue 30. 2018-04-23. PMID:28467778. |
double staining with cd68 was used to exclude microglia and macrophages from analyses. |
2018-04-23 |
2023-08-13 |
Not clear |
| Andrew J Riquier, Suzanne I Sollar. Microglia density decreases in the rat rostral nucleus of the solitary tract across development and increases in an age-dependent manner following denervation. Neuroscience. vol 355. 2018-03-28. PMID:28478126. |
brain tissue was stained for iba1 or cd68, and both the density and morphology of microglia were assessed on the intact and transected sides of the rnts. |
2018-03-28 |
2023-08-13 |
rat |
| Wei Han, Takashi Umekawa, Kai Zhou, Xing-Mei Zhang, Makiko Ohshima, Cecilia A Dominguez, Robert A Harris, Changlian Zhu, Klas Blomgre. Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia. Oncotarget. vol 7. issue 50. 2018-02-21. PMID:27793054. |
cd68 was expressed in 90% of amoeboid microglia in juvenile hippocampi but only in 9% of adult ones. |
2018-02-21 |
2023-08-13 |
mouse |
| Erming Wang, Haihao Zhu, Xiaofan Wang, Adam C Gower, Max Wallack, Jan Krzysztof Blusztajn, Neil Kowall, Wei Qiao Qi. Amylin Treatment Reduces Neuroinflammation and Ameliorates Abnormal Patterns of Gene Expression in the Cerebral Cortex of an Alzheimer's Disease Mouse Model. Journal of Alzheimer's disease : JAD. vol 56. issue 1. 2018-02-21. PMID:27911303. |
mechanistic studies indicated the protective effect of amylin required interaction with its cognate receptor because silencing the amylin receptor expression blocked the amylin effect on cd68 in microglia. |
2018-02-21 |
2023-08-13 |
mouse |
| Alexandra M Johnson, Ella Sugo, Daniela Barreto, Chee-Chung Hiew, John A Lawson, Anne M Connolly, Ernest Somerville, Enisa Hasic, Annie Me Bye, Anne M Cunningha. The Severity of Gliosis in Hippocampal Sclerosis Correlates with Pre-Operative Seizure Burden and Outcome After Temporal Lobectomy. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26452360. |
temporal lobe specimens were examined by dab immunohistochemistry for astrocytes (glial fibrillary acidic protein (gfap)) and microglia (cd68). |
2018-01-22 |
2023-08-13 |
Not clear |
| Elisa R Zanier, Federica Marchesi, Fabrizio Ortolano, Carlo Perego, Maedeh Arabian, Tommaso Zoerle, Eliana Sammali, Francesca Pischiutta, Maria-Grazia De Simon. Fractalkine Receptor Deficiency Is Associated with Early Protection but Late Worsening of Outcome following Brain Trauma in Mice. Journal of neurotrauma. vol 33. issue 11. 2018-01-04. PMID:26180940. |
microglia (m) and macrophage (μ) activation and polarization were assessed by quantitative immunohistochemistry for cd11b, cd68, ym1, and inducible nitric oxide synthase (inos)-markers of m/μ activation, phagocytosis, m2, and m1 phenotypes, respectively. |
2018-01-04 |
2023-08-13 |
mouse |
| Cheryl Reeves, Mohamed Tachrount, David Thomas, Zuzanna Michalak, Joan Liu, Matthew Ellis, Beate Diehl, Anna Miserocchi, Andrew W McEvoy, Sofia Eriksson, Tarek Yousry, Maria Tho. Combined Ex Vivo 9.4T MRI and Quantitative Histopathological Study in Normal and Pathological Neocortical Resections in Focal Epilepsy. Brain pathology (Zurich, Switzerland). vol 26. issue 3. 2018-01-02. PMID:26268959. |
quantitative immunohistochemistry for myelination (myelin basic protein/smi94), neuronal populations [microtubule-associated protein 2 (map2), neurofilament (smi31, smi32), synaptophysin, neun, calbindin], reactive glia (gfap), microglia (cd68) and blood-brain barrier permeability (albumin) was carried out in 43 regions of interest (roi) from normal and abnormal white matter and cortex. |
2018-01-02 |
2023-08-13 |
Not clear |
| Hai-Yun Wu, Xue-Qi Tang, Xiao-Fang Mao, Yong-Xiang Wan. Autocrine Interleukin-10 Mediates Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin Expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 48. 2017-12-07. PMID:29084866. |
treatment with exenatide in cultured primary spinal microglia concentration dependently stimulated the expression of the m2 microglial markers il-10, il-4, arg 1, and cd206, but not the m1 microglial markers tnf-α, il-1β, il-6, or cd68. |
2017-12-07 |
2023-08-13 |
rat |
| Jonathan D Cherry, Yorghos Tripodis, Victor E Alvarez, Bertrand Huber, Patrick T Kiernan, Daniel H Daneshvar, Jesse Mez, Philip H Montenigro, Todd M Solomon, Michael L Alosco, Robert A Stern, Ann C McKee, Thor D Stei. Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy. Acta neuropathologica communications. vol 4. issue 1. 2017-10-25. PMID:27793189. |
duration of rhi exposure and the development and severity of cte were associated with reactive microglial morphology and increased numbers of cd68 immunoreactive microglia in the dlf. |
2017-10-25 |
2023-08-13 |
human |
| Camille Planty, Corey P Mallett, Kevin Yim, Jorge C G Blanco, Marina Boukhvalova, Thomas March, Robbert van der Most, Eric Destexh. Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats. Human vaccines & immunotherapeutics. vol 13. issue 1. 2017-10-23. PMID:27629482. |
potential effects on the cns were investigated by histopathological evaluation of brain sections stained with hematoxylin-and-eosin, or by immunohistochemical staining of microglia, using iba1 and cd68 as markers for microglia identification/activation, albumin as indicator of vascular leakage, and hypocretin. |
2017-10-23 |
2023-08-13 |
rat |
| Diane M Brooks, Sarjubhai A Patel, Eric D Wohlgehagen, Erin O Semmens, Alan Pearce, Edmond A Sorich, Thomas F Ra. Multiple mild traumatic brain injury in the rat produces persistent pathological alterations in the brain. Experimental neurology. vol 297. 2017-10-05. PMID:28756201. |
cd68 positive microglia were significantly increased in the ipsilateral corpus callosum, cortex, and internal capsule of injured animals. |
2017-10-05 |
2023-08-13 |
rat |
| Giovanni Marfia, Stefania Elena Navone, Loubna Abdel Hadi, Moira Paroni, Valeria Berno, Matteo Beretta, Roberta Gualtierotti, Francesca Ingegnoli, Vincenzo Levi, Monica Miozzo, Jens Geginat, Lorenzo Fassina, Paolo Rampini, Carlo Tremolada, Laura Riboni, Rolando Campanell. The Adipose Mesenchymal Stem Cell Secretome Inhibits Inflammatory Responses of Microglia: Evidence for an Involvement of Sphingosine-1-Phosphate Signalling. Stem cells and development. vol 25. issue 14. 2017-09-11. PMID:27217090. |
our results demonstrate that the conditioned medium (cm) of adscs isolated by two different processing methods (lipoaspirate and lipogems) significantly inhibited the lipopolysaccharide (lps)-induced effects on microglia activation, including microglial expression of cd68, cytokine secretion, proliferation, and migration. |
2017-09-11 |
2023-08-13 |
human |
| Debbie A E Hendrickx, Corbert G van Eden, Karianne G Schuurman, Jörg Hamann, Inge Huiting. Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology. Journal of neuroimmunology. vol 309. 2017-08-21. PMID:28601280. |
staining of hla-dr, iba1 and cd68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology. |
2017-08-21 |
2023-08-13 |
human |