| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Oehmichen, I Theuerkauf, C Meissne. Is traumatic axonal injury (AI) associated with an early microglial activation? Application of a double-labeling technique for simultaneous detection of microglia and AI. Acta neuropathologica. vol 97. issue 5. 2000-02-01. PMID:10334486. |
in 40 selected cases of confirmed ai, the topographical relation of ai and microglial reaction was assessed using an immunohistochemical double-labeling technique for simultaneous demonstration of ai using beta-amyloid precursor protein (beta-app) antibody and of microglia using cd68 antibody. |
2000-02-01 |
2023-08-12 |
Not clear |
| P Rezaie, K Patel, D K Mal. Microglia in the human fetal spinal cord--patterns of distribution, morphology and phenotype. Brain research. Developmental brain research. vol 115. issue 1. 1999-08-03. PMID:10366704. |
human fetal microglia display heterogeneity in phenotype and are more readily identified by cd68 in the spinal cord. |
1999-08-03 |
2023-08-12 |
human |
| W F Reynolds, J Rhees, D Maciejewski, T Paladino, H Sieburg, R A Maki, E Maslia. Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease. Experimental neurology. vol 155. issue 1. 1999-03-18. PMID:9918702. |
microglia costaining for mpo and cd68 are closely associated with plaques, suggesting that plaque components induce mpo expression in microglia. |
1999-03-18 |
2023-08-12 |
Not clear |
| A V Andjelkovic, B Nikolic, J S Pachter, N Zecevi. Macrophages/microglial cells in human central nervous system during development: an immunohistochemical study. Brain research. vol 814. issue 1-2. 1999-03-16. PMID:9838024. |
), using lectins, ricinus communis agglutinin-1 [rca-1], and lycopersicon esculentum, tomato lectin (tl), which recognize macrophages and microglia, and antibodies for the macrophage antigen cd68. |
1999-03-16 |
2023-08-12 |
human |
| A V Andjelkovic, B Nikolic, J S Pachter, N Zecevi. Macrophages/microglial cells in human central nervous system during development: an immunohistochemical study. Brain research. vol 814. issue 1-2. 1999-03-16. PMID:9838024. |
our finding that one class of cells can be labeled early only with lectins, while another can be labeled with both lectins and cd68 macrophage antibody, may reflect a different origin of microglia in the early embryonic cns compared to the fetal stages. |
1999-03-16 |
2023-08-12 |
human |
| M L Zhao, J S Liu, D He, D W Dickson, S C Le. Inducible nitric oxide synthase expression is selectively induced in astrocytes isolated from adult human brain. Brain research. vol 813. issue 2. 1999-01-05. PMID:9838203. |
cell types were determined by morphology as well as immunocytochemistry for gfap (astrocytes) and cd68 (microglia). |
1999-01-05 |
2023-08-12 |
human |
| A B Schmitt, G A Brook, A Buss, W Nacimiento, J Noth, G W Kreutzber. Dynamics of microglial activation in the spinal cord after cerebral infarction are revealed by expression of MHC class II antigen. Neuropathology and applied neurobiology. vol 24. issue 3. 1998-11-06. PMID:9717181. |
in the white matter, the removal of degenerating axons by phagocytosing microglia expressing hla-dr and cd68 antigens is a slower process which occurs over a period of months. |
1998-11-06 |
2023-08-12 |
Not clear |
| L F Lue, L Brachova, D G Walker, J Roger. Characterization of glial cultures from rapid autopsies of Alzheimer's and control patients. Neurobiology of aging. vol 17. issue 3. 1996-12-03. PMID:8725904. |
cultured microglia phagocytosed latex beads, were reactive for dil-acetylated low density lipoprotein, were immunoreactive for cd68 and major histocompatibility complex ii markers, and were not immunoreactive for fibroblast, astrocyte, or oligodendrocyte markers. |
1996-12-03 |
2023-08-12 |
human |
| M Oehmichen, C Meissner, A Reiter, M Birkhol. Neuropathology in non-human immunodeficiency virus-infected drug addicts: hypoxic brain damage after chronic intravenous drug abuse. Acta neuropathologica. vol 91. issue 6. 1996-12-03. PMID:8781664. |
by contrast, in nearly 80% of these cases, the hippocampus showed enhanced expression of glial fibrillary acid protein by astrocytes and/or a proliferation of microglia, demonstrated by cd68 expression. |
1996-12-03 |
2023-08-12 |
human |
| H Mühleisen, J Gehrmann, R Meyerman. Reactive microglia in Creutzfeldt-Jakob disease. Neuropathology and applied neurobiology. vol 21. issue 6. 1996-10-09. PMID:8745240. |
we have, therefore, examined six brains from cases of sporadic cjd by immunohistochemical labelling of grey and white matter microglia from frontal, parietal, temporal, and occipital lobes, striatum, thalamus, cerebellum and brain stem with rca-1, lca, cd68, hla-dr, and ham56. |
1996-10-09 |
2023-08-12 |
Not clear |
| S C Dollard, H J James, L R Sharer, L G Epstein, H A Gelbard, S Dewhurs. Activation of nuclear factor kappa B in brains from children with HIV-1 encephalitis. Neuropathology and applied neurobiology. vol 21. issue 6. 1996-10-09. PMID:8745241. |
double-labelling studies using antibodies to cd68, or rca-1 lectin, markers for cells of monocyte/macrophage lineage, revealed an increase in the number of microglia and macrophages with nuclear immunoreactivity for nf kappa b in association with hiv-1 encephalitis. |
1996-10-09 |
2023-08-12 |
human |
| C M Hulett. Microglioma, a histiocytic neoplasm of the central nervous system. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. vol 9. issue 3. 1996-08-22. PMID:8685234. |
the neoplastic cells stained intensely with cd68 (kp1) and ricinus communis agglutinin-120 markers for microglia and also with ham-56, a marker for macrophages. |
1996-08-22 |
2023-08-12 |
Not clear |
| E Ulvestad, K Williams, R Bjerkvig, K Tiekotter, J Antel, R Matr. Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells. Journal of leukocyte biology. vol 56. issue 6. 1995-01-19. PMID:7996050. |
we find that human microglia have ultrastructural, phenotypic (cd11c, cd68, acid phosphatase), and functional (fcr and cr mediated phagocytosis) properties typical for cells of the monocyte lineage. |
1995-01-19 |
2023-08-12 |
human |
| W D Lyman, W C Hatch, E Pousada, G Stephney, W K Rashbaum, K M Weidenhei. Human fetal myelinated organotypic cultures. Brain research. vol 599. issue 1. 1993-03-05. PMID:1493548. |
the explants were maintained for up to 12 weeks during which time they were characterized and shown to express a number of cns cell-type-specific markers including glial fibrillary acidic protein (astrocytes), nerve growth factor receptor and neurofilament protein (neurons), cd68 (microglia), and myelin basic protein, hnk-1 and galactocerebroside (oligodendrocytes). |
1993-03-05 |
2023-08-11 |
human |
| K D Hutchins, D W Dickson, W K Rashbaum, W D Lyma. Localization of microglia in the human fetal cervical spinal cord. Brain research. Developmental brain research. vol 66. issue 2. 1992-07-23. PMID:1606692. |
ebm-11, a monoclonal antibody that recognizes cd68 on human macrophages, and microglia labeled only ameboid-type microglia in the developing white matter. |
1992-07-23 |
2023-08-11 |
human |
| K D Hutchins, D W Dickson, W K Rashbaum, W D Lyma. Localization of microglia in the human fetal cervical spinal cord. Brain research. Developmental brain research. vol 66. issue 2. 1992-07-23. PMID:1606692. |
this suggests that distinct subpopulations of microglia exist, which may represent different stages in microglial development, and that cd68 may be a differentiation marker for less mature forms. |
1992-07-23 |
2023-08-11 |
human |
| C M Hulette, B T Downey, P C Burge. Macrophage markers in diagnostic neuropathology. The American journal of surgical pathology. vol 16. issue 5. 1992-07-06. PMID:1376020. |
(b) cd68 is a specific marker for resting microglia. |
1992-07-06 |
2023-08-11 |
Not clear |