Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
E Ulvestad, K Williams, R Bjerkvig, K Tiekotter, J Antel, R Matr. Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells. Journal of leukocyte biology. vol 56. issue 6. 1995-01-19. PMID:7996050. |
we find that human microglia have ultrastructural, phenotypic (cd11c, cd68, acid phosphatase), and functional (fcr and cr mediated phagocytosis) properties typical for cells of the monocyte lineage. |
1995-01-19 |
2023-08-12 |
human |
W D Lyman, W C Hatch, E Pousada, G Stephney, W K Rashbaum, K M Weidenhei. Human fetal myelinated organotypic cultures. Brain research. vol 599. issue 1. 1993-03-05. PMID:1493548. |
the explants were maintained for up to 12 weeks during which time they were characterized and shown to express a number of cns cell-type-specific markers including glial fibrillary acidic protein (astrocytes), nerve growth factor receptor and neurofilament protein (neurons), cd68 (microglia), and myelin basic protein, hnk-1 and galactocerebroside (oligodendrocytes). |
1993-03-05 |
2023-08-11 |
human |
K D Hutchins, D W Dickson, W K Rashbaum, W D Lyma. Localization of microglia in the human fetal cervical spinal cord. Brain research. Developmental brain research. vol 66. issue 2. 1992-07-23. PMID:1606692. |
ebm-11, a monoclonal antibody that recognizes cd68 on human macrophages, and microglia labeled only ameboid-type microglia in the developing white matter. |
1992-07-23 |
2023-08-11 |
human |
K D Hutchins, D W Dickson, W K Rashbaum, W D Lyma. Localization of microglia in the human fetal cervical spinal cord. Brain research. Developmental brain research. vol 66. issue 2. 1992-07-23. PMID:1606692. |
this suggests that distinct subpopulations of microglia exist, which may represent different stages in microglial development, and that cd68 may be a differentiation marker for less mature forms. |
1992-07-23 |
2023-08-11 |
human |
C M Hulette, B T Downey, P C Burge. Macrophage markers in diagnostic neuropathology. The American journal of surgical pathology. vol 16. issue 5. 1992-07-06. PMID:1376020. |
(b) cd68 is a specific marker for resting microglia. |
1992-07-06 |
2023-08-11 |
Not clear |