| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura M Navarro-Saiz, Lilia J Bernal-Cepeda, Jaime E Castellano. Immune challenges upregulate the expression of cannabinoid receptors in cultured human odontoblasts and gingival fibroblasts. Acta odontologica latinoamericana : AOL. vol 35. issue 2. 2022-10-19. PMID:36260938. |
in conclusion, human odontoblasts and gingival fibroblasts express functional cb1 and cb2 cannabinoid receptors, which could be modulated to improve the treatment of pain or dental sensitivity. |
2022-10-19 |
2023-08-14 |
human |
| Laura López-Gómez, Agata Szymaszkiewicz, Marta Zielińska, Raquel Abal. The Enteric Glia and Its Modulation by the Endocannabinoid System, a New Target for Cannabinoid-Based Nutraceuticals? Molecules (Basel, Switzerland). vol 27. issue 19. 2022-10-14. PMID:36235308. |
the endogenous cannabinoid system (ecs) includes endogenous classical cannabinoids (anandamide, 2-arachidonoylglycerol), cannabinoid-like ligands (oleoylethanolamide (oea) and palmitoylethanolamide (pea)), enzymes involved in their metabolism (faah, magl, cox-2) and classical (cb1 and cb2) and non-classical (trpv1, gpr55, ppar) receptors. |
2022-10-14 |
2023-08-14 |
Not clear |
| Elina Avraamidou, Moritz Nöthel, Melina Danisch, Laura Bindila, Susanne V Schmidt, Beat Lutz, Georg Nickenig, Julian Jehl. Myeloid But Not Endothelial Expression of the CB2 Receptor Promotes Atherogenesis in the Context of Elevated Levels of the Endocannabinoid 2-Arachidonoylglycerol. Journal of cardiovascular translational research. 2022-09-30. PMID:36178662. |
myeloid but not endothelial expression of the cb2 receptor promotes atherogenesis in the context of elevated levels of the endocannabinoid 2-arachidonoylglycerol. |
2022-09-30 |
2023-08-14 |
mouse |
| Elina Avraamidou, Moritz Nöthel, Melina Danisch, Laura Bindila, Susanne V Schmidt, Beat Lutz, Georg Nickenig, Julian Jehl. Myeloid But Not Endothelial Expression of the CB2 Receptor Promotes Atherogenesis in the Context of Elevated Levels of the Endocannabinoid 2-Arachidonoylglycerol. Journal of cardiovascular translational research. 2022-09-30. PMID:36178662. |
the endocannabinoid 2-arachidonoylglycerol (2-ag) is an inflammatory mediator and ligand for the cannabinoid receptors cb1 and cb2. |
2022-09-30 |
2023-08-14 |
mouse |
| Valentina Rinaldi, Andrea Boari, Lorenzo Ressel, Laura Bongiovanni, Paolo Emidio Crisi, Emanuele Cabibbo, Riccardo Finotell. Expression of cannabinoid receptors CB1 and CB2 in canine cutaneous mast cell tumours. Research in veterinary science. vol 152. 2022-09-30. PMID:36179546. |
expression of cannabinoid receptors cb1 and cb2 in canine cutaneous mast cell tumours. |
2022-09-30 |
2023-08-14 |
Not clear |
| Valentina Rinaldi, Andrea Boari, Lorenzo Ressel, Laura Bongiovanni, Paolo Emidio Crisi, Emanuele Cabibbo, Riccardo Finotell. Expression of cannabinoid receptors CB1 and CB2 in canine cutaneous mast cell tumours. Research in veterinary science. vol 152. 2022-09-30. PMID:36179546. |
cannabinoid receptors (cb1 and cb2) belong to endocannabinoid system (ecs), which is also composed from endocannabinoids and the enzymatic systems involved in their biosynthesis and degradation. |
2022-09-30 |
2023-08-14 |
Not clear |
| María Victoria Noya-Riobó, Constanza Ágata Miguel, Delia Beatriz Soriano, Pablo Rodolfo Brumovsky, Marcelo José Villar, María Florencia Corone. Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences. Experimental neurology. 2022-09-30. PMID:36179876. |
the mrna levels corresponding to cannabinoid receptors (cb1, cb2), cannabinoid-related receptors (gpr55, 5ht1a, trpv1) and to the main enzymes involved in the synthesis (dagl, dagl, nape-pld) and degradation (mgl, faah) of endocannabinoids were assessed in lumbar dorsal root ganglia (drgs) and spinal cord by using real time rt-pcr. |
2022-09-30 |
2023-08-14 |
rat |
| Diego Mauricio Gómez-García, Herney Andrés García-Perdom. Medical cannabis: Critical points for clinical application Biomedica : revista del Instituto Nacional de Salud. vol 42. issue 3. 2022-09-19. PMID:36122285. |
these compounds have several physiological effects and produce their effects primarily by binding to endogenous cannabinoid receptors such as cb1 and cb2, among others.cannabis has potential therapeutic properties and its preparations have been used as traditional remedies to treat pain and emesis. |
2022-09-19 |
2023-08-14 |
Not clear |
| Hayder M Al-Kuraishy, Ali I Al-Gareeb, Athanasios Alexiou, Gaber El-Saber Batih. Cannabinoids receptors in Covid-19: Perpetrators and victims. Current medicinal chemistry. 2022-08-31. PMID:36043749. |
cannabinoids (cbs) such as tetrahydrocannabinol (thc) and cannabidiol (cbd), which act on g-protein-coupled receptors called cb1 and cb2, have anti-inflammatory effects. |
2022-08-31 |
2023-08-14 |
Not clear |
| Anthony S Ferranti, Daniel J Foste. Cannabinoid type-2 receptors: An emerging target for regulating schizophrenia-relevant brain circuits. Frontiers in neuroscience. vol 16. 2022-08-29. PMID:36033626. |
although the cannabinoid type-2 receptor (cb2) is highly expressed in the immune system, emerging evidence points to cb2 playing a key role in regulating neuronal function in the central nervous system. |
2022-08-29 |
2023-08-14 |
Not clear |
| Valeria Gasperi, Tatiana Guzzo, Alessandra Topai, Nicola Gambacorta, Fulvio Ciriaco, Orazio Nicolotti, Mauro Maccarron. Recent Advances on Type-2 Cannabinoid (CB2) Receptor Agonists and Their Therapeutic Potential. Current medicinal chemistry. 2022-08-27. PMID:36028971. |
recent advances on type-2 cannabinoid (cb2) receptor agonists and their therapeutic potential. |
2022-08-27 |
2023-08-14 |
Not clear |
| Valeria Gasperi, Tatiana Guzzo, Alessandra Topai, Nicola Gambacorta, Fulvio Ciriaco, Orazio Nicolotti, Mauro Maccarron. Recent Advances on Type-2 Cannabinoid (CB2) Receptor Agonists and Their Therapeutic Potential. Current medicinal chemistry. 2022-08-27. PMID:36028971. |
in the last decade, selective modulators of type-2 cannabinoid receptor (cb2) have become a major focus to target endocannabinoid signaling in humans. |
2022-08-27 |
2023-08-14 |
Not clear |
| P H Gobira, S R Joca, F A Moreir. Roles of cannabinoid CB1 and CB2 receptors in the modulation of psychostimulant responses. Acta neuropsychiatrica. 2022-08-22. PMID:35993329. |
roles of cannabinoid cb1 and cb2 receptors in the modulation of psychostimulant responses. |
2022-08-22 |
2023-08-14 |
Not clear |
| Sherelle L Casey, Vanessa A Mitchell, Eddy E Sokolaj, Bryony L Winters, Christopher W Vaugha. Intrathecal Actions of the Cannabis Constituents Δ(9)-Tetrahydrocannabinol and Cannabidiol in a Mouse Neuropathic Pain Model. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955774. |
the anti-allodynic effects of thc were abolished and partly reduced by cannabinoid cb1 and cb2 receptor antagonists am281 and am630, respectively. |
2022-08-12 |
2023-08-14 |
mouse |
| Francesca Punzo, Maura Argenziano, Chiara Tortora, Alessandra Di Paola, Margherita Mutarelli, Elvira Pota, Martina Di Martino, Daniela Di Pinto, Maria Maddalena Marrapodi, Domenico Roberti, Francesca Ross. Effect of CB2 Stimulation on Gene Expression in Pediatric B-Acute Lymphoblastic Leukemia: New Possible Targets. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955786. |
cannabinoids, enzymes involved in their metabolism, and cannabinoid receptors type 1 (cb1) and type 2 (cb2) constitute the endocannabinoid system, involved in inflammation, immune response, and cancer. |
2022-08-12 |
2023-08-14 |
human |
| Zak M Whiting, Jiazhen Yin, Sara M de la Harpe, Andrea J Vernall, Natasha L Grimse. Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future. Trends in pharmacological sciences. 2022-07-29. PMID:35906103. |
a diverse pharmacopoeia of cannabinoid ligands is available, which has led to considerable advancements in the understanding of cb2 function and extensive preclinical evaluation. |
2022-07-29 |
2023-08-14 |
Not clear |
| Mahendra Kumar Trivedi, Sambhu Mondal, Snehasis Jan. Cannabidiol improves thyroid function via modulating vitamin D Journal of food science and technology. vol 59. issue 8. 2022-07-25. PMID:35872737. |
cannabidiol improves thyroid function via modulating vitamin d the study was evaluated the impact of cannabidiol (cbd) on thyroid hormones by modulation cannabinoid receptor-2 (cb2) and vitamin d receptor (vdr) in rats fed with vitamin d |
2022-07-25 |
2023-08-14 |
rat |
| Armin Aryannejad, Faezeh Eslami, Maryam Shayan, Nafise Noroozi, Keshvad Hedayatyanfard, Seyed Mohammad Tavangar, Razieh Mohammad Jafari, Ahmad Reza Dehpou. Cannabidiol Improves Random-Pattern Skin Flap Survival in Rats: Involvement of Cannabinoid Type-2 Receptors. Journal of reconstructive microsurgery. 2022-07-11. PMID:35817049. |
we aimed to evaluate the efficacy of cbd on the random-pattern skin flap survival (sfs) in rats and to explore the possible involvement of cannabinoid type-2 (cb2) receptors. |
2022-07-11 |
2023-08-14 |
rat |
| Shahab Alizadeh, Kurosh Djafarian, Maryam Mofidi Nejad, Mir Saeed Yekaninejad, Mohammad Hassan Javanbakh. The effect of β-caryophyllene on food addiction and its related behaviors: A randomized, double-blind, placebo-controlled trial. Appetite. 2022-07-09. PMID:35809704. |
β-caryophyllene is a dietary cannabinoid that is a cannabinoid type 2 (cb2) receptor agonist. |
2022-07-09 |
2023-08-14 |
Not clear |
| Farinaz Ghaderi, Fattah Sotoodehnejadnematalahi, Zahra Hajebrahimi, Abolfazl Fateh, Seyed Davar Siada. Effects of active, inactive, and derivatives of Akkermansia muciniphila on the expression of the endocannabinoid system and PPARs genes. Scientific reports. vol 12. issue 1. 2022-06-15. PMID:35705595. |
this study aimed to investigate the effects of active and heat-inactivated forms of akkermansia muciniphila, bacterium-derived outer membrane vesicles (omvs), and cell-free supernatant on the transcription of endocannabinoid system (ecs) members, including cannabinoid receptors 1 and 2 (cb1 and cb2), fatty acid amide hydrolase (faah), and peroxisome proliferator-activated receptors (ppars) genes (i.e., α, β/δ, and δ) in caco-2 and hepg-2 cell lines. |
2022-06-15 |
2023-08-14 |
Not clear |