| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarah Allam, Elizabeth Paris, Itzel Lazcano, Pincas Bitterman, Sanjib Basu, James O'Donnell, Animesh Baru. Detection of Cannabinoid Receptor Expression by Endometriotic Lesions in Women with Endometriosis as an Alternative to Opioid-Based Pain Medication. Journal of immunology research. vol 2022. 2022-06-13. PMID:35692500. |
the goal of this study was to examine whether cannabinoid receptors 1 and 2 (cb1 and cb2) are expressed by ovarian endometriotic lesions. |
2022-06-13 |
2023-08-14 |
Not clear |
| María Salud García-Gutiérrez, Francisco Navarrete, Ani Gasparyan, Daniela Navarro, Álvaro Morcuende, Teresa Femenía, Jorge Manzanare. Role of Cannabinoid CB2 Receptor in Alcohol Use Disorders: From Animal to Human Studies. International journal of molecular sciences. vol 23. issue 11. 2022-06-10. PMID:35682586. |
role of cannabinoid cb2 receptor in alcohol use disorders: from animal to human studies. |
2022-06-10 |
2023-08-14 |
human |
| María Salud García-Gutiérrez, Francisco Navarrete, Ani Gasparyan, Daniela Navarro, Álvaro Morcuende, Teresa Femenía, Jorge Manzanare. Role of Cannabinoid CB2 Receptor in Alcohol Use Disorders: From Animal to Human Studies. International journal of molecular sciences. vol 23. issue 11. 2022-06-10. PMID:35682586. |
cumulative evidence has pointed out cannabinoid cb2 receptors (cb |
2022-06-10 |
2023-08-14 |
human |
| Marek Zubrzycki, Maria Zubrzycka, Grzegorz Wysiadecki, Janusz Szemraj, Hanna Jerczynska, Mariusz Stasiole. Release of Endocannabinoids into the Cerebrospinal Fluid during the Induction of the Trigemino-Hypoglossal Reflex in Rats. Current issues in molecular biology. vol 44. issue 5. 2022-06-09. PMID:35678693. |
the concentrations of the endocannabinoids tested (aea and 2-ag) were determined in the csf, along with the expression of the cannabinoid receptors (cb1 and cb2) in the tissues of the mesencephalon, thalamus, and hypothalamus. |
2022-06-09 |
2023-08-14 |
rat |
| Yongsoon Park, Bruce A Watkin. Dietary PUFA and Exercise Dynamic Actions on Endocannabinoids in Brain - Consequences for Neural Plasticity and Neuroinflammation. Advances in nutrition (Bethesda, Md.). 2022-06-08. PMID:35675221. |
the ecbs bind to cannabinoid receptors cb1 and cb2 to exert a wide range of activities, such as stimulate appetite, influence energy metabolism, support the immune system, and facilitate neuroplasticity. |
2022-06-08 |
2023-08-14 |
human |
| Alessandra Manca, Alice Palermiti, Jacopo Mula, Elisa Delia De Vivo, Sandra Zeaiter, Marco Simiele, Amedeo De Nicolò, Marco Cantù, Jessica Cusato, Antonio D'Avoli. A description of Cannabinoid levels in Cannabis oil by high-performance liquid chromatography-mass spectrometry in a reference laboratory of North-Italy. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 102. 2022-06-06. PMID:35665680. |
several studies showed cannabinoids action on cb1 and cb2 receptors reduces the hyperalgesic phase in inflammatory pain, leading to an improvement of conditions. |
2022-06-06 |
2023-08-14 |
Not clear |
| You-Ming Deng, Cheng Zhao, Lei Wu, Zhan Qu, Xin-Yu Wan. Cannabinoid Receptor-1 suppresses M2 macrophage polarization in colorectal cancer by downregulating EGFR. Cell death discovery. vol 8. issue 1. 2022-05-31. PMID:35641479. |
cannabinoid receptors, cb1 and cb2, have been implicated as emerging targets for cancer therapy. |
2022-05-31 |
2023-08-13 |
Not clear |
| Harshal D Pawar, Umesh B Mahajan, Kartik T Nakhate, Yogeeta O Agrawal, Chandragouda R Patil, M F Nagoor Meeran, Charu Sharma, Shreesh Ojha, Sameer N Goya. Curcumin Protects Diabetic Mice against Isoproterenol-Induced Myocardial Infarction by Modulating CB2 Cannabinoid Receptors. Life (Basel, Switzerland). vol 12. issue 5. 2022-05-28. PMID:35629293. |
curcumin protects diabetic mice against isoproterenol-induced myocardial infarction by modulating cb2 cannabinoid receptors. |
2022-05-28 |
2023-08-13 |
mouse |
| Sonia Kiran, Ahmed Rakib, Bob M Moore, Udai P Sing. Cannabinoid Receptor 2 (CB2) Inverse Agonist SMM-189 Induces Expression of Endogenous CB2 and Protein Kinase A That Differentially Modulates the Immune Response and Suppresses Experimental Colitis. Pharmaceutics. vol 14. issue 5. 2022-05-28. PMID:35631522. |
cannabinoids mediate protection against intestinal inflammation by binding to the g-protein coupled cannabinoid receptors 1 and 2 (cb1 and cb2). |
2022-05-28 |
2023-08-13 |
mouse |
| Valéria de Almeida, Gabriela Seabra, Guilherme Reis-de-Oliveira, Giuliana S Zuccoli, Priscila Rumin, Mariana Fioramonte, Bradley J Smith, Antonio W Zuardi, Jaime E C Hallak, Alline C Campos, José A Crippa, Daniel Martins-de-Souz. Cannabinoids modulate proliferation, differentiation, and migration signaling pathways in oligodendrocytes. European archives of psychiatry and clinical neuroscience. 2022-05-27. PMID:35622101. |
cannabinoid signaling, mainly via cb1 and cb2 receptors, plays an essential role in oligodendrocyte health and functions. |
2022-05-27 |
2023-08-13 |
human |
| Bitya Raphael-Mizrahi, Malka Attar-Lamdar, Mukesh Chourasia, Maria G Cascio, Avital Shurki, Joseph Tam, Moshe Neuman, Neta Rimmerman, Zvi Vogel, Arie Shteyer, Roger G Pertwee, Andreas Zimmer, Natalya Kogan, Itai Bab, Yankel Gabe. Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2. eLife. vol 11. 2022-05-23. PMID:35604006. |
the endocannabinoid system consists mainly of 2-arachidonoylglycerol and anandamide, as well as cannabinoid receptor type 1 (cb1) and type 2 (cb2). |
2022-05-23 |
2023-08-13 |
mouse |
| Francesca Gado, Rebecca Ferrisi, Sarah Di Somma, Fabiana Napolitano, Kawthar A Mohamed, Lesley A Stevenson, Simona Rapposelli, Giuseppe Saccomanni, Giuseppe Portella, Roger G Pertwee, Robert B Laprairie, Anna Maria Malfitano, Clementina Maner. Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells. Molecules (Basel, Switzerland). vol 27. issue 9. 2022-05-14. PMID:35566369. |
synthesis and in vitro characterization of selective cannabinoid cb2 receptor agonists: biological evaluation against neuroblastoma cancer cells. |
2022-05-14 |
2023-08-13 |
Not clear |
| Anthony S Ferranti, Tazeen Ishmam, Isaiah C Swann, Jennifer Du, Janet Mariadoss, Lindsley W Craig, Jerri M Rook, Peter J Conn, Daniel J Foste. CB2 Receptor Potentiation Mediates Antipsychotic-like Efficacy in Mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35553978. |
although the cannabinoid type-2 receptor (cb2) is highly expressed in the immune system, emerging evidence points to cb2 playing a key role in regulating neuronal function in the central nervous system (cns). |
2022-05-13 |
2023-08-13 |
mouse |
| Victoria L Vernail, Sarah S Bingaman, Wesley M Raup-Konsavage, Kent E Vrana, Amy C Arnol. Acute Cannabigerol Administration Lowers Blood Pressure in Mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555999. |
while cbg can bind to cannabinoid receptors cb1 and cb2, it has also been described as an agonist at α2-adrenoreceptors (a2-ar), which when activated inhibit the release of norepinephrine from α-adrenergic neurons. |
2022-05-13 |
2023-08-13 |
mouse |
| Christina A Brust, Jo-Hao Ho, Edward Stahl, Christos Iliopoulos-Tsoutsouvas, Spyros Nikas, Alexandros Makriyannis, Laura Boh. Functional analysis of key residues involved in CB1 and CB2 activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560902. |
human endocannabinoid signaling is primarily mediated by the g-protein coupled receptors cb1 and cb2. |
2022-05-13 |
2023-08-13 |
human |
| Virna Margarita Martín Giménez, Luciana Mazzei, Raúl Sanz, Walter Manuch. Cannabinoids as Potential Molecules for Addiction Disorders. Current protein & peptide science. 2022-05-11. PMID:35538819. |
to highlight, cannabinoid receptors, types 1 and 2 (cb1 and cb2) have a crucial role in modulating the anti-addictive properties of these compounds. |
2022-05-11 |
2023-08-13 |
Not clear |
| Zachary W Reichenbach, Kelly DiMattio, Suren Rajakaruna, David Ambrose, William D Cornwell, Ronald J Tallarida, Thomas Rogers, Lee-Yuan Liu-Chen, Ronald F Tuma, Sara Jane War. Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966. Frontiers in pharmacology. vol 13. 2022-05-09. PMID:35529434. |
modulation of morphine analgesia, antinociceptive tolerance, and mu-opioid receptor binding by the cannabinoid cb2 receptor agonist o-1966. |
2022-05-09 |
2023-08-13 |
mouse |
| Zachary W Reichenbach, Kelly DiMattio, Suren Rajakaruna, David Ambrose, William D Cornwell, Ronald J Tallarida, Thomas Rogers, Lee-Yuan Liu-Chen, Ronald F Tuma, Sara Jane War. Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966. Frontiers in pharmacology. vol 13. 2022-05-09. PMID:35529434. |
activation of cannabinoid cb2 receptors reverses allodynia and hyperalgesia in models of chronic pain, and co-administration of morphine with cb2 receptor selective agonists has been shown to be synergistic. |
2022-05-09 |
2023-08-13 |
mouse |
| Krishna Ghosh, Guang-Fen Zhang, Hong Chen, Shao-Rui Chen, Hui-Lin Pa. Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain. The Journal of biological chemistry. 2022-05-02. PMID:35500651. |
cannabinoid cb2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain. |
2022-05-02 |
2023-08-13 |
rat |
| Krishna Ghosh, Guang-Fen Zhang, Hong Chen, Shao-Rui Chen, Hui-Lin Pa. Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain. The Journal of biological chemistry. 2022-05-02. PMID:35500651. |
type-2 cannabinoid receptors (cb2, encoded by the cnr2 gene) are mainly expressed in immune cells, and cb2 agonists normally have no analgesic effect. |
2022-05-02 |
2023-08-13 |
rat |