| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Emadi, H Jonaidi, E Hosseini Amir Aba. The role of central CB2 cannabinoid receptors on food intake in neonatal chicks. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 197. issue 12. 2012-03-19. PMID:21927979. |
the role of central cb2 cannabinoid receptors on food intake in neonatal chicks. |
2012-03-19 |
2023-08-12 |
Not clear |
| R Maldonado, F Berrendero, A Ozaita, P Robled. Neurochemical basis of cannabis addiction. Neuroscience. vol 181. 2012-03-16. PMID:21334423. |
the psychoactive compounds contained in cannabis induce their pharmacological effects by the activation of at least two different receptors, cb1 and cb2 cannabinoid receptors. |
2012-03-16 |
2023-08-12 |
Not clear |
| A J Sánchez, A García-Merin. Neuroprotective agents: cannabinoids. Clinical immunology (Orlando, Fla.). vol 142. issue 1. 2012-03-06. PMID:21420365. |
through activation of the cb2 receptor, cannabinoids modulate peripheral blood lymphocytes, interfere with migration across the blood-brain barrier and control microglial/macrophage activation. |
2012-03-06 |
2023-08-12 |
human |
| Friedrich Felix Hoyer, Martin Steinmetz, Sebastian Zimmer, Astrid Becker, Dieter Lütjohann, Rainer Buchalla, Andreas Zimmer, Georg Nickeni. Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo. Journal of molecular and cellular cardiology. vol 51. issue 6. 2012-03-05. PMID:21884703. |
atherosclerosis prone apolipoprotein e-deficient mice were crossed with cannabinoid receptor-2 deficient mice to obtain apoe -/- cb2 -/- double knockout mice. |
2012-03-05 |
2023-08-12 |
mouse |
| Agata M Wasik, Birger Christensson, Birgitta Sande. The role of cannabinoid receptors and the endocannabinoid system in mantle cell lymphoma and other non-Hodgkin lymphomas. Seminars in cancer biology. vol 21. issue 5. 2012-03-01. PMID:22024769. |
the g protein coupled receptors cannabinoid receptors 1 and 2 (cb1 and cb2) are expressed at low levels on non-malignant lymphocytes and at higher levels in mcl and other lymphoma subtypes. |
2012-03-01 |
2023-08-12 |
Not clear |
| Javier Palazuelos, Zaira Ortega, Javier Díaz-Alonso, Manuel Guzmán, Ismael Galve-Roper. CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling. The Journal of biological chemistry. vol 287. issue 2. 2012-02-27. PMID:22102284. |
cb2 cannabinoid receptors promote neural progenitor cell proliferation via mtorc1 signaling. |
2012-02-27 |
2023-08-12 |
mouse |
| Udai P Singh, Narendra P Singh, Balwan Singh, Robert L Price, Mitzi Nagarkatti, Prakash S Nagarkatt. Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis. Toxicology and applied pharmacology. vol 258. issue 2. 2012-02-23. PMID:22119709. |
cannabinoid receptor-2 (cb2) agonist ameliorates colitis in il-10(-/-) mice by attenuating the activation of t cells and promoting their apoptosis. |
2012-02-23 |
2023-08-12 |
mouse |
| Udai P Singh, Narendra P Singh, Balwan Singh, Robert L Price, Mitzi Nagarkatti, Prakash S Nagarkatt. Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis. Toxicology and applied pharmacology. vol 258. issue 2. 2012-02-23. PMID:22119709. |
here, we investigate the effect of cannabinoid receptor-2 (cb2) agonist, jwh-133, after chronic colitis in il-10(-/-) mice. |
2012-02-23 |
2023-08-12 |
mouse |
| Yuxun Zhang, Zhaojun Xie, Lirong Wang, Brielle Schreiter, John S Lazo, Jurg Gertsch, Xiang-Qun Xi. Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor. International immunopharmacology. vol 11. issue 9. 2012-02-16. PMID:21539938. |
w5.43(194), a conserved tryptophan residue among g-protein coupled receptors (gpcrs) and cannabinoid receptors (cb), was examined in the present report for its significance in cb2 receptor ligand binding and adenylyl cyclase (ac) activity. |
2012-02-16 |
2023-08-12 |
Not clear |
| Dorota Latek, Michal Kolinski, Umesh Ghoshdastider, Aleksander Debinski, Rafal Bombolewski, Anita Plazinska, Krzysztof Jozwiak, Slawomir Filipe. Modeling of ligand binding to G protein coupled receptors: cannabinoid CB1, CB2 and adrenergic β 2 AR. Journal of molecular modeling. vol 17. issue 9. 2012-01-20. PMID:21365223. |
modeling of ligand binding to g protein coupled receptors: cannabinoid cb1, cb2 and adrenergic β 2 ar. |
2012-01-20 |
2023-08-12 |
Not clear |
| S Petrosino, B Ménard, N Zsürger, V Di Marzo, J Chabr. Alteration of the endocannabinoid system in mouse brain during prion disease. Neuroscience. vol 177. 2012-01-19. PMID:21195746. |
the cb2 receptor expression was up-regulated in brains of prion-infected mice as early as 10 weeks and up to 32 weeks post-infection whereas the mrnas of other cannabinoid receptors (cbrs) remain unchanged. |
2012-01-19 |
2023-08-12 |
mouse |
| Sreemanti Basu, Bonnie N Ditte. Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease. Immunologic research. vol 51. issue 1. 2012-01-19. PMID:21626285. |
it has become clear that the endocannabinoid system is a potent regulator of immune responses, with the cannabinoid receptor 2 (cb2) as the key component due to its high expression by all immune subtypes. |
2012-01-19 |
2023-08-12 |
Not clear |
| Catherine Lombard, Venkatesh L Hegde, Mitzi Nagarkatti, Prakash S Nagarkatt. Perinatal exposure to Δ9-tetrahydrocannabinol triggers profound defects in T cell differentiation and function in fetal and postnatal stages of life, including decreased responsiveness to HIV antigens. The Journal of pharmacology and experimental therapeutics. vol 339. issue 2. 2012-01-16. PMID:21831965. |
we noted that murine fetal thymus expressed high levels of the cannabinoid receptors cb1 and cb2. |
2012-01-16 |
2023-08-12 |
mouse |
| Sreemanti Basu, Avijit Ray, Bonnie N Ditte. Cannabinoid receptor 2 is critical for the homing and retention of marginal zone B lineage cells and for efficient T-independent immune responses. Journal of immunology (Baltimore, Md. : 1950). vol 187. issue 11. 2012-01-13. PMID:22048769. |
the endocannabinoid system has emerged as an important regulator of immune responses, with the cannabinoid receptor 2 (cb2) and its principle ligand 2-archidonoylglycerol playing a major role. |
2012-01-13 |
2023-08-12 |
mouse |
| L Peralta, E Agirregoitia, R Mendoza, A Expósito, L Casis, R Matorras, N Agirregoiti. Expression and localization of cannabinoid receptors in human immature oocytes and unfertilized metaphase-II oocytes. Reproductive biomedicine online. vol 23. issue 3. 2012-01-12. PMID:21778114. |
thus, in order to develop knowledge in this field, in the present study we have described the presence of the cannabinoid receptors cb1 and cb2 (the proteins required to mediate the action of the cannabinoids) in the early stages of meiotic resumption of oocytes (the stages before ovulation) and we could postulate that the endocannabinoids could act in the regulation of maturation of oocytes. |
2012-01-12 |
2023-08-12 |
human |
| Nashaat Turkman, Aleksander Shavrin, Roman A Ivanov, Brian Rabinovich, Andrei Volgin, Juri G Gelovani, Mian M Alauddi. Fluorinated cannabinoid CB2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives. Bioorganic & medicinal chemistry. vol 19. issue 18. 2012-01-10. PMID:21872477. |
fluorinated cannabinoid cb2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives. |
2012-01-10 |
2023-08-12 |
human |
| Arnab Banerjee, Ajit Singh, Puneet Srivastava, Helen Turner, Amitabh Krishn. Effects of chronic bhang (cannabis) administration on the reproductive system of male mice. Birth defects research. Part B, Developmental and reproductive toxicology. vol 92. issue 3. 2012-01-09. PMID:21678546. |
an attempt was also made to investigate the presence of cannabinoid 1 (cb1) and cannabinoid 2 (cb2) receptors, and fatty acid amide hydrolase (faah) in the testis and to evaluate any changes in it resulting from chronic intake of bhang in mice. |
2012-01-09 |
2023-08-12 |
mouse |
| J-Z Chen, K-Z Myint, X-Q Xi. New QSAR prediction models derived from GPCR CB2-antagonistic triaryl bis-sulfone analogues by a combined molecular morphological and pharmacophoric approach. SAR and QSAR in environmental research. vol 22. issue 5-6. 2012-01-09. PMID:21714749. |
in order to build quantitative structure-activity relationship (qsar) models for virtual screening of novel cannabinoid cb2 ligands and hit ranking selections, a new qsar algorithm has been developed for the cannabinoid ligands, triaryl bis-sulfones, using a combined molecular morphological and pharmacophoric search approach. |
2012-01-09 |
2023-08-12 |
Not clear |
| Mario van der Stelt, Jos Cals, Silvia Broeders-Josten, Jean Cottney, Antoon A van der Doelen, Marcel Hermkens, Vera de Kimpe, Angela King, Jan Klomp, Julia Oosterom, Ilse Pols-de Rooij, Jeroen de Roos, Martin van Tilborg, Susan Boyce, James Bake. Discovery and optimization of 1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives as a novel class of selective cannabinoid CB2 receptor agonists. Journal of medicinal chemistry. vol 54. issue 20. 2012-01-03. PMID:21923175. |
discovery and optimization of 1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives as a novel class of selective cannabinoid cb2 receptor agonists. |
2012-01-03 |
2023-08-12 |
rat |
| Mario van der Stelt, Jos Cals, Silvia Broeders-Josten, Jean Cottney, Antoon A van der Doelen, Marcel Hermkens, Vera de Kimpe, Angela King, Jan Klomp, Julia Oosterom, Ilse Pols-de Rooij, Jeroen de Roos, Martin van Tilborg, Susan Boyce, James Bake. Discovery and optimization of 1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives as a novel class of selective cannabinoid CB2 receptor agonists. Journal of medicinal chemistry. vol 54. issue 20. 2012-01-03. PMID:21923175. |
here, we report the identification and optimization of 1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives as a novel chemotype with selective cannabinoid cb2 receptor agonist activity. |
2012-01-03 |
2023-08-12 |
rat |