| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tang-feng Su, Ling-hong Zhang, Miao Peng, Cai-hua Wu, Wen Pan, Bo Tian, Jing Shi, Hui-lin Pan, Man L. Cannabinoid CB2 receptors contribute to upregulation of β-endorphin in inflamed skin tissues by electroacupuncture. Molecular pain. vol 7. 2012-09-19. PMID:22177137. |
endogenous cannabinoids and peripheral cannabinoid cb2 receptors (cb2rs) are also involved in the antinociceptive effect of ea on inflammatory pain. |
2012-09-19 |
2023-08-12 |
Not clear |
| Nashaat Turkman, Aleksander Shavrin, Vincenzo Paolillo, Hsin Hsien Yeh, Leo Flores, Suren Soghomonian, Brian Rabinovich, Andrei Volgin, Juri Gelovani, Mian Alauddi. Synthesis and preliminary evaluation of [18F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB2 receptor. Nuclear medicine and biology. vol 39. issue 4. 2012-09-17. PMID:22226022. |
synthesis and preliminary evaluation of [18f]-labeled 2-oxoquinoline derivatives for pet imaging of cannabinoid cb2 receptor. |
2012-09-17 |
2023-08-12 |
Not clear |
| Yosefa Avraham, Johnny Amer, Sarit Doron, Lina Abu-Tair, Mahmud Mahamid, Areej Khatib, Elliot M Berry, Rifaat Safad. The direct profibrotic and indirect immune antifibrotic balance of blocking the cannabinoid 2 receptor. American journal of physiology. Gastrointestinal and liver physiology. vol 302. issue 12. 2012-09-13. PMID:22517772. |
cannabinoid 2 (cb2) receptors expressed on immune cells are considered to be antifibrogenic. |
2012-09-13 |
2023-08-12 |
mouse |
| Doris Riethe. Selective cannabinoid receptor 2 modulators: a patent review 2009--present. Expert opinion on therapeutic patents. vol 22. issue 5. 2012-09-06. PMID:22537079. |
questions around the involvement of cb1 activation in these effects remain, but efforts have been directed toward the discovery of highly selective cb2 modulators lacking the psychotropic effects of cannabinoids, which are mediated by the cb1 receptor. |
2012-09-06 |
2023-08-12 |
Not clear |
| Francesca Rossi, Giulia Bellini, Carlo Tolone, Livio Luongo, Silvia Mancusi, Alfonso Papparella, Craig Sturgeon, Alessio Fasano, Bruno Nobili, Laura Perrone, Sabatino Maione, Emanuele Miraglia del Giudic. The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention. Pharmacological research. vol 66. issue 1. 2012-08-27. PMID:22465144. |
cells of the immune system express the cannabinoid receptor type 2 (cb2), a plasma-membrane receptor activated by both endogenous and exogenous cannabinoids. |
2012-08-27 |
2023-08-12 |
Not clear |
| Lucía Callén, Estefanía Moreno, Pedro Barroso-Chinea, David Moreno-Delgado, Antoni Cortés, Josefa Mallol, Vicent Casadó, José Luis Lanciego, Rafael Franco, Carmen Lluis, Enric I Canela, Peter J McCormic. Cannabinoid receptors CB1 and CB2 form functional heteromers in brain. The Journal of biological chemistry. vol 287. issue 25. 2012-08-24. PMID:22532560. |
cannabinoid receptors cb1 and cb2 form functional heteromers in brain. |
2012-08-24 |
2023-08-12 |
rat |
| Emmanuel S Onaivi, Hiroki Ishiguro, Shanzhi Gu, Qing-Rong Li. CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity. Journal of psychopharmacology (Oxford, England). vol 26. issue 1. 2012-08-21. PMID:21447538. |
cns effects of cb2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity. |
2012-08-21 |
2023-08-12 |
mouse |
| Pál Pacher, Ken Macki. Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration. Journal of molecular medicine (Berlin, Germany). vol 90. issue 4. 2012-08-17. PMID:22371074. |
interplay of cannabinoid 2 (cb2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration. |
2012-08-17 |
2023-08-12 |
Not clear |
| Nima Naderi, Leila Ahmad-Molaei, Ali Mazar-Atabaki, Abdolaziz Ronaghi, Zahra Shirazi-zand, Seyed Mehrdad Motiei-Langroudi, Somayeh Eslahka. L-type calcium channel mediates anticonvulsant effect of cannabinoids in acute and chronic murine models of seizure. Neurochemical research. vol 37. issue 2. 2012-08-13. PMID:21928146. |
moreover, (r)-(+)-[2,3-dihydro-5-methyl-3[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate (win55,212-2), the non-selective cannabinoid cb1 and cb2 receptor agonist showed anticonvulsant effect in amygdala-kindled rats. |
2012-08-13 |
2023-08-12 |
mouse |
| Wei Xiong, Tanxing Cui, Kejun Cheng, Fei Yang, Shao-Rui Chen, Dan Willenbring, Yun Guan, Hui-Lin Pan, Ke Ren, Yan Xu, Li Zhan. Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. The Journal of experimental medicine. vol 209. issue 6. 2012-08-13. PMID:22585736. |
in contrast, the cannabinoid analgesia is neither correlated with their binding affinity for cb1 and cb2 receptors nor with their psychoactive side effects. |
2012-08-13 |
2023-08-12 |
mouse |
| Peng-Fei Wang, Li-Sheng Jiang, Jun Bu, Xiao-Jin Huang, Wei Song, Yong-Ping Du, Ben H. Cannabinoid-2 receptor activation protects against infarct and ischemia-reperfusion heart injury. Journal of cardiovascular pharmacology. vol 59. issue 4. 2012-08-10. PMID:22113346. |
in conclusion, the endocannabinoid system was activated during ami and ir, and cb2 receptor activation produces a protective role, thus offering a novel pharmaceutical target for treating these diseases. |
2012-08-10 |
2023-08-12 |
mouse |
| Eleonora Patsenker, Matthias Stoll, Gunda Millonig, Abbas Agaimy, Till Wissniowski, Vreni Schneider, Sebastian Mueller, Rudolf Brenneisen, Helmut K Seitz, Matthias Ocker, Felix Sticke. Cannabinoid receptor type I modulates alcohol-induced liver fibrosis. Molecular medicine (Cambridge, Mass.). vol 17. issue 11-12. 2012-08-03. PMID:21863215. |
the cannabinoid system (cs) is implicated in the regulation of hepatic fibrosis, steatosis and inflammation, with cannabinoid receptors 1 and 2 (cb1 and cb2) being involved in regulation of pro- and antifibrogenic effects. |
2012-08-03 |
2023-08-12 |
mouse |
| T-F Su, Y-Q Zhao, L-H Zhang, M Peng, C-H Wu, L Pei, B Tian, J Zhang, J Shi, H-L Pan, M L. Electroacupuncture reduces the expression of proinflammatory cytokines in inflamed skin tissues through activation of cannabinoid CB2 receptors. European journal of pain (London, England). vol 16. issue 5. 2012-08-01. PMID:22337285. |
electroacupuncture reduces the expression of proinflammatory cytokines in inflamed skin tissues through activation of cannabinoid cb2 receptors. |
2012-08-01 |
2023-08-12 |
rat |
| T-F Su, Y-Q Zhao, L-H Zhang, M Peng, C-H Wu, L Pei, B Tian, J Zhang, J Shi, H-L Pan, M L. Electroacupuncture reduces the expression of proinflammatory cytokines in inflamed skin tissues through activation of cannabinoid CB2 receptors. European journal of pain (London, England). vol 16. issue 5. 2012-08-01. PMID:22337285. |
endogenous cannabinoids and peripheral cannabinoid cb2 receptors (cb2rs) are involved in the antinociceptive effect of electroacupuncture (ea) on inflammatory pain. |
2012-08-01 |
2023-08-12 |
rat |
| Bėla Horváth, Lital Magid, Partha Mukhopadhyay, Sándor Bátkai, Mohanraj Rajesh, Ogyi Park, Galin Tanchian, Rachel Y Gao, Catherine E Goodfellow, Michelle Glass, Raphael Mechoulam, Pál Pache. A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21449982. |
a new cannabinoid cb2 receptor agonist hu-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury. |
2012-07-27 |
2023-08-12 |
Not clear |
| Sándor Bátkai, Partha Mukhopadhyay, Bėla Horváth, Mohanraj Rajesh, Rachel Y Gao, Anu Mahadevan, Mukkanti Amere, Natalia Battista, Aron H Lichtman, Lisa A Gauson, Mauro Maccarrone, Roger G Pertwee, Pál Pache. Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21470208. |
Δ8-tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid cb2 receptors. |
2012-07-27 |
2023-08-12 |
Not clear |
| Lamont Booker, Steven G Kinsey, Rehab A Abdullah, Jacqueline L Blankman, Jonathan Z Long, Cyrine Ezzili, Dale L Boger, Benjamin F Cravatt, Aron H Lichtma. The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21506952. |
one potential target to treat inflammatory pain is the endogenous cannabinoid (endocannabinoid) system, which is comprised of cb1 and cb2 cannabinoid receptors and several endogenous ligands, including anandamide (aea). |
2012-07-27 |
2023-08-12 |
mouse |
| Daniele Bolognini, Maria Grazia Cascio, Daniela Parolaro, Roger G Pertwe. AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21615724. |
am630 behaves as a protean ligand at the human cannabinoid cb2 receptor. |
2012-07-27 |
2023-08-12 |
human |
| Takayuki Mimura, Yoshifumi Ueda, Yoshihiro Watanabe, Takayuki Sugiur. The cannabinoid receptor-2 is involved in allergic inflammation. Life sciences. vol 90. issue 21-22. 2012-07-23. PMID:22525379. |
to investigate the role of cannabinoid receptor-2 (cb2) in allergic inflammation in cb2 knockout (cb2-ko) mice. |
2012-07-23 |
2023-08-12 |
mouse |
| P W Brownjohn, J C Ashto. Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury. Neuroscience. vol 203. 2012-07-19. PMID:22210507. |
spinal cannabinoid cb2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury. |
2012-07-19 |
2023-08-12 |
rat |