| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Başak Işıl Zorba, Özge Boyacioğlu, Tuğba Çağlayan, Tuba Reçber, Emirhan Nemutlu, İpek Eroğlu, Petek Korkusu. CB65 and novel CB65 liposomal system suppress MG63 and Saos-2 osteosarcoma cell growth in vitro. Journal of liposome research. 2023-09-23. PMID:37740901. |
cannabinoid ligands exert antiproliferative and apoptotic effect on osteosarcoma cells via cannabinoid 2 (cb2) or transient receptor potential vanilloid type (trpv1) receptors. |
2023-09-23 |
2023-10-07 |
Not clear |
| Ji-de Zheng, Feng-Qiang Sun, Mei-Juan Mia. [Research progress of acupuncture mediated analgesia via regulating the function of endocannabinoid system]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 9. 2023-09-20. PMID:37730267. |
by reviewing literatures related to acupuncture analgesia and ecs, we summarized the effect and mechanism of acupuncture analgesia involved with regulation of ecs, pointed out cannabinoid (cb) 1 receptor and cb2 receptor exerted analgesic effect in central and peripheral neural system through mechanisms of inhibiting neural activation and anti-inflammation, respectively. |
2023-09-20 |
2023-10-07 |
Not clear |
| Michael Maes, Muanpetch Rachayon, Ketsupar Jirakran, Atapol Sughondhabirom, Abbas F Almulla, Pimpayao Sodsa. Role of T and B lymphocyte cannabinoid type 1 and 2 receptors in major depression and suicidal behaviors. Acta neuropsychiatrica. 2023-09-08. PMID:37681553. |
this study examines the number of cannabinoid type 1 (cb1) and type 2 (cb2) receptor bearing t/b lymphocytes in mdd, and the effects of in vitro cannabidiol (cbd) administration on cb1/cb2-bearing immunocytes. |
2023-09-08 |
2023-10-07 |
Not clear |
| Ziteng Wang, Eric Yu Quan Leow, Hooi Yan Moy, Eric Chun Yong Cha. Advances in urinary biomarker research of synthetic cannabinoids. Advances in clinical chemistry. vol 115. 2023-09-06. PMID:37673518. |
synthetic cannabinoids (scs) are a subclass of nps which bind to the cannabinoid receptors, cb1 and cb2, and mimic the action of cannabis. |
2023-09-06 |
2023-10-07 |
human |
| Christina A Brust, Matthew A Swanson, Laura M Boh. Structural and functional insights into the G protein-coupled receptors: CB1 and CB2. Biochemical Society transactions. vol 51. issue 4. 2023-08-30. PMID:37646476. |
the cannabinoid receptors cb1 and cb2 mediate a variety of physiological processes and continue to be explored as desirable drug targets. |
2023-08-30 |
2023-09-07 |
Not clear |
| Christina A Brust, Matthew A Swanson, Laura M Boh. Structural and functional insights into the G protein-coupled receptors: CB1 and CB2. Biochemical Society transactions. vol 51. issue 4. 2023-08-30. PMID:37646476. |
these structures will provide additional insight into the modulation and signaling mechanism of cannabinoid receptors cb1 and cb2 and aid in the development of future therapeutics. |
2023-08-30 |
2023-09-07 |
Not clear |
| Hebaallah Mamdouh Hashiesh, Azimullah Sheikh, Mohamed Fizur Nagoor Meeran, Dhanya Saraswathiamma, Niraj Kumar Jha, Bassem Sadek, Ernest Adeghate, Saeed Tariq, Saeeda Al Marzooqi, Shreesh Ojh. β-Caryophyllene, a Dietary Phytocannabinoid, Alleviates Diabetic Cardiomyopathy in Mice by Inhibiting Oxidative Stress and Inflammation Activating Cannabinoid Type-2 Receptors. ACS pharmacology & translational science. vol 6. issue 8. 2023-08-17. PMID:37588762. |
recently, it has been revealed that cannabinoid type-2 (cb2) receptors, an essential component of the endocannabinoid system, play a crucial role in the pathogenesis of obesity, hyperlipidemia, and dm. |
2023-08-17 |
2023-09-07 |
mouse |
| Pranay Wal, Ankita Wa. CBD: A Potential Lead against Hair Loss, Alopecia, and its Potential Mechanisms. Current drug discovery technologies. 2023-07-21. PMID:37475557. |
due to the presence of the endocannabinoid system (ecs) in the body, which naturally targets cb1 and cb2 receptors, the control of hair fall is possible. |
2023-07-21 |
2023-08-14 |
Not clear |
| J Maia, B M Fonseca, N Teixeira, G Correia-da-Silv. Unveiling the Angiogenic Effects of Cannabinoids: Enhancers or inhibitors? Biochemical pharmacology. 2023-07-18. PMID:37463627. |
some can activate the cannabinoid receptors type-1 and -2 (cb1 and cb2), that are part of the endocannabinoid system (ecs), alongside the endocannabinoids and their metabolic enzymes. |
2023-07-18 |
2023-08-14 |
Not clear |
| Analia Young Hwa Cho, Hery Chung, Javier Romero-Parra, Poulami Kumar, Marco Allarà, Alessia Ligresti, Carlos Gallardo-Garrido, Hernán Pessoa-Mahana, Mario Faúndez, Carlos David Pessoa-Mahan. Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[ International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446093. |
its two main receptors, cannabinoid type 1 (cb1) and type 2 (cb2) receptors, mediate anti-inflammatory responses; however, their differing patterns of expression make the development of cb2-selective ligands therapeutically more attractive. |
2023-07-14 |
2023-08-14 |
Not clear |
| Liana Arceri, Thanh Khoa Nguyen, Shannon Gibson, Sophia Baker, Rebecca A Winger. Cannabinoid Signaling in Kidney Disease. Cells. vol 12. issue 10. 2023-07-06. PMID:37408253. |
the two cannabinoid receptors, cb1 and cb2, are cell membrane proteins that interact with both exogenous and endogenous bioactive lipid ligands, or endocannabinoids. |
2023-07-06 |
2023-08-14 |
human |
| Dina Medina-Vera, Hongjing Zhao, Erika Bereczki, Cristina Rosell-Valle, Makoto Shimozawa, Gefei Chen, Fernando Rodríguez de Fonseca, Per Nilsson, Simone Tambar. The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer's Disease in Biology. vol 12. issue 6. 2023-06-28. PMID:37372090. |
the expression of the endocannabinoid receptors cb2 and gpr55 is highly increased during the progression of alzheimer's disease in the endocannabinoid system (ecs) and associated lipid transmitter-based signaling systems play an important role in modulating brain neuroinflammation. |
2023-06-28 |
2023-08-14 |
Not clear |
| Dina Medina-Vera, Hongjing Zhao, Erika Bereczki, Cristina Rosell-Valle, Makoto Shimozawa, Gefei Chen, Fernando Rodríguez de Fonseca, Per Nilsson, Simone Tambar. The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer's Disease in Biology. vol 12. issue 6. 2023-06-28. PMID:37372090. |
here we have evaluated the non-psychotropic endocannabinoid receptor type 2 (cb2) and lysophosphatidylinositol g-protein-coupled receptor 55 (gpr55) localization and expression during aβ-pathology progression. |
2023-06-28 |
2023-08-14 |
Not clear |
| Kelsey G Guenther, Zhili Xu, Julian Romero, Cecilia J Hillard, Ken Mackie, Andrea G Hohman. Conditional deletion of CB2 cannabinoid receptors from peripheral sensory neurons eliminates CB2-mediated antinociceptive efficacy in a mouse model of carrageenan-induced inflammatory pain. Neuropharmacology. 2023-06-07. PMID:37286073. |
conditional deletion of cb2 cannabinoid receptors from peripheral sensory neurons eliminates cb2-mediated antinociceptive efficacy in a mouse model of carrageenan-induced inflammatory pain. |
2023-06-07 |
2023-08-14 |
mouse |
| Karina Henrique Binda, Marucia Chacur, Daniel Oliveira Martin. Exercise Improves Orofacial Pain and Modifies Neuropeptide Expression in a Rat Model of Parkinson's Disease. Neurotoxicity research. 2023-06-02. PMID:37266893. |
in order to confirm the possible involvement of cannabinoid receptors, we also injected antagonists of cb1 and cb2 receptors. |
2023-06-02 |
2023-08-14 |
rat |
| Cristina Izquierdo-Luengo, Marc Ten-Blanco, María Ponce-Renilla, Ramiro Perezzan, Inmaculada Pereda-Pérez, Fernando Berrender. Adolescent exposure to the Spice/K2 cannabinoid JWH-018 impairs sensorimotor gating and alters cortical perineuronal nets in a sex-dependent manner. Translational psychiatry. vol 13. issue 1. 2023-05-24. PMID:37225721. |
a transitory decrease in the expression of gad67 and cb2 cannabinoid receptors in the prefrontal cortex was also found in male mice exposed to jwh-018. |
2023-05-24 |
2023-08-14 |
mouse |
| Jennifer Ana Iden, Bitya Raphael-Mizrahi, Aaron Naim, Albert Kolomansky, Tamar Liron, Drorit Neumann, Marilena Vered, Yankel Gabe. The Anti-Tumorigenic Role of Cannabinoid Receptor 2 in Non-Melanoma Skin Cancer. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37175480. |
the dysregulation of the endocannabinoid system, particularly cannabinoid receptor 2 (cb2), is implicated in skin cancer development, progression, and metastasis. |
2023-05-14 |
2023-08-14 |
Not clear |
| Margaryta Tevosian, Hristo Todorov, Ermelinda Lomazzo, Laura Bindila, Natsuo Ueda, Davide Bassetti, Davide Warm, Sergei Kirischuk, Heiko J Luhmann, Susanne Gerber, Beat Lut. NAPE-PLD deletion in stress-TRAPed neurons results in an anxiogenic phenotype. Translational psychiatry. vol 13. issue 1. 2023-05-06. PMID:37149657. |
anandamide (aea) is an endogenous ligand of the cannabinoid cb1 and cb2 receptors, being a component of the endocannabinoid signaling system, which supports the maintenance or regaining of neural homeostasis upon internal and external challenges. |
2023-05-06 |
2023-08-14 |
mouse |
| Sumit S Rathod, Yogeeta O Agrawa. Phytocannabinoids as Potential Multitargeting Neuroprotectants in Alzheimer's Disease. Current drug research reviews. 2023-05-03. PMID:37132109. |
the present article also discusses the implications of cannabinoid receptors (cb1 and cb2) as well as cannabinoid enzymes (faah and magl) modulators in ad. |
2023-05-03 |
2023-08-14 |
Not clear |
| Ankush Kumar, Ojasvi Gupta, Rohit Bhatia, VikramDeep Mong. Impact of Cannabinoid Receptors in the Design of Therapeutic Agents against Human Ailments. Current topics in medicinal chemistry. 2023-05-03. PMID:37132103. |
the endocannabinoid system comprises canna-binoid receptors cb1 and cb2, which belong to g-protein coupled receptors (gpcrs). |
2023-05-03 |
2023-08-14 |
human |