| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Barbara Broers, Federica Bianch. Cannabinoids for Behavioral Symptoms in Dementia: An Overview. Pharmacopsychiatry. 2024-03-06. PMID:38447959. |
cannabinoids are lipophilic molecules acting on the cb1 end cb2 receptors, essential for main biological processes such as sleep, appetite, memory, and pain. |
2024-03-06 |
2024-03-09 |
Not clear |
| Dongchen An, Guilherme Salgado Carrazoni, Ben-Hur Souto das Neves, Rudi D'Hooge, Steve Peigneur, Jan Tytga. The Sobering Sting: Oleoyl Serotonin Is a Novel Biomedicines. vol 12. issue 2. 2024-02-24. PMID:38398056. |
the sobering sting: oleoyl serotonin is a novel cannabinoid receptors (cb1 and cb2) are promising targets for a better understanding of neurological diseases. |
2024-02-24 |
2024-02-26 |
mouse |
| Aaliyah Roberts, Mahli Christian, Lizbeth Nivar Dilone, Natania Nelson, Mark Joseph Endrino, Adam Kneebone, Shymaa Embaby, Justin Fernandez, Qing-Rong Liu, Emmanuel S Onaivi, Berhanu Geresu Kibre. Alcohol induced behavioral and immune perturbations are attenuated by activation of CB2 cannabinoid receptors. Advances in drug and alcohol research. vol 3. 2024-02-23. PMID:38389814. |
alcohol induced behavioral and immune perturbations are attenuated by activation of cb2 cannabinoid receptors. |
2024-02-23 |
2024-02-25 |
mouse |
| Laura V de Paus, Yu An, Antonius P A Janssen, Richard J B H N Van den Berg, Laura H Heitman, Mario Van der Stel. Discovery of a Photoaffinity Probe that Captures the Active Conformation of the Cannabinoid CB2 Receptor. Chembiochem : a European journal of chemical biology. 2024-02-19. PMID:38372466. |
discovery of a photoaffinity probe that captures the active conformation of the cannabinoid cb2 receptor. |
2024-02-19 |
2024-02-21 |
Not clear |
| Stefano Pagano, Chiara Valenti, Paolo Negri, Monia Billi, Alessandro Di Michele, Stefano Bruscoli, Marta Febo, Maddalena Coniglio, Lorella Marinucc. Acute and chronic cannabidiol treatment: In vitro toxicological aspects on human oral cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-02-11. PMID:38342230. |
viability, morphology, migration, apoptosis and cell cycle, and expression of related genes (p53, bcl2, p21, and bax) and of endocannabinoid system receptors (cb1, cb2 and gpr55) with real-time pcr and dna damage with phospho-γ-h2ax immunofluorescence detection were analyzed. |
2024-02-11 |
2024-02-14 |
human |
| Sagar A More, Rucha S Deore, Harshal D Pawar, Charu Sharma, Kartik T Nakhate, Sumit S Rathod, Shreesh Ojha, Sameer N Goya. CB2 Cannabinoid Receptor as a Potential Target in Myocardial Infarction: Exploration of Molecular Pathogenesis and Therapeutic Strategies. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338960. |
the primary targets of cannabinoids are cannabinoid type 1 (cb1) and 2 (cb2) receptors. |
2024-02-10 |
2024-02-12 |
Not clear |
| Wen-Hao Liu, Jun-Shang Wu, Li-Bo Hua, Zhi-Feng Pan, Hai-Bo Zhang, Neng-Gui Xu, Yi-Han H. Advances in the study of endocannabinoid receptors in experimental acupuncture analgesia. Zhen ci yan jiu = Acupuncture research. vol 49. issue 1. 2024-01-19. PMID:38239143. |
among which the endocannabinoid receptors ［including type i (cb1) and type ii (cb2) receptors］ play an important role in the regulation of pain and have become an important target in the mechanism research of acupuncture analgesia. |
2024-01-19 |
2024-01-21 |
human |
| John Staton Laws Iii, Scott D Smi. Sesquiterpene-evoked phytochemical toxicity in PC12 neuronal cells reveals a variable degree of oxidative stress and alpha-tocopherol and glutathione-dependent protection. Current research in toxicology. vol 6. 2024-01-09. PMID:38193034. |
both β-caryophyllene- and humulene-evoked toxicity was unaffected by cb1 or cb2 receptor antagonism, demonstrating this occurred independently of cannabinoid receptors. |
2024-01-09 |
2024-01-10 |
rat |
| Di Cui, Yuanyuan Zhang, Mingyue Zhan. The effect of cannabinoid type 2 receptor agonist on morphine tolerance. IBRO neuroscience reports. vol 16. 2023-12-25. PMID:38145173. |
previous studies have shown that a cannabinoid type 2 (cb2) receptor agonist could attenuate morphine tolerance in a variety of animal models. |
2023-12-25 |
2023-12-27 |
Not clear |
| Ana Canseco-Alba, Koichi Tabata, Momoki Yukihiko, Taharima Tabassum, Yasue Horiuchi, Tadao Arinami, Emmanuel S Onaivi, Hiroki Ishigur. Cannabinoid CB2 receptors and hypersensitivity to methamphetamine: Vulnerability to schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. 2023-12-22. PMID:38135096. |
cannabinoid cb2 receptors and hypersensitivity to methamphetamine: vulnerability to schizophrenia. |
2023-12-22 |
2023-12-25 |
mouse |
| b' A Pa\\xc5\\x99\\xc3\\xadzek, J Suchop\\xc3\\xa1r, Z La\\xc5\\xa1t\\xc5\\xafvka, M Alblov\\xc3\\xa1, M Hill, M Du\\xc5\\xa1kov\\xc3\\xa. The Endocannabinoid System and Its Relationship to Human Reproduction. Physiological research. vol 72. issue S4. 2023-12-20. PMID:38116770.' |
only an exceptional interplay of enzymes such as nape-pdl or faah, endogenous cannabinoids and cannabinoid receptors cb1 and cb2 can ensure the proper functioning of the reproductive organs and thus lead to delivery on time. |
2023-12-20 |
2023-12-23 |
human |
| Huaqiang Tao, Xueyan Li, Miao Chu, Qiufei Wang, Ping Li, Qibin Han, Kai Chen, Pengfei Zhu, Yuefeng Hao, Xing Yang, Dechun Geng, Ye G. CB2 regulates oxidative stress and osteoclastogenesis through NOX1-dependent signaling pathway in titanium particle-induced osteolysis. Cell death discovery. vol 9. issue 1. 2023-12-19. PMID:38104087. |
cannabinoid type ii receptor (cb2) is a seven-transmembrane receptor that is predominantly distributed in the human immune system and has been revealed to be highly expressed in bone-associated cells. |
2023-12-19 |
2023-12-21 |
human |
| Yan Costa Gonçalves, Karina Carla de Francisco Campos, Eliton da Silva Vasconcelos, Beatriz Micucci D'Almeida Eça, Francisco Tadeu Rantin, Ana Lúcia Kalinin, Diana Amaral Monteir. Activation of the cannabinoid type 2 (CB2) receptor improves cardiac contractile performance in fish, Brycon amazonicus. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023-12-19. PMID:38113964. |
activation of the cannabinoid type 2 (cb2) receptor improves cardiac contractile performance in fish, brycon amazonicus. |
2023-12-19 |
2023-12-23 |
Not clear |
| Yan Costa Gonçalves, Karina Carla de Francisco Campos, Eliton da Silva Vasconcelos, Beatriz Micucci D'Almeida Eça, Francisco Tadeu Rantin, Ana Lúcia Kalinin, Diana Amaral Monteir. Activation of the cannabinoid type 2 (CB2) receptor improves cardiac contractile performance in fish, Brycon amazonicus. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023-12-19. PMID:38113964. |
in addition to their well-known classical effects, cannabinoid cb1 and cb2 receptors have also been involvement in both deleterious and protective actions on the heart under various pathological conditions. |
2023-12-19 |
2023-12-23 |
Not clear |
| Yan Costa Gonçalves, Karina Carla de Francisco Campos, Eliton da Silva Vasconcelos, Beatriz Micucci D'Almeida Eça, Francisco Tadeu Rantin, Ana Lúcia Kalinin, Diana Amaral Monteir. Activation of the cannabinoid type 2 (CB2) receptor improves cardiac contractile performance in fish, Brycon amazonicus. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023-12-19. PMID:38113964. |
while the potential therapeutic applications of the endocannabinoid system in the context of cardiovascular function are indeed a viable prospect, significant debate exists within the literature regarding whether cb1, cb2, or a combination of both receptors exert a favorable influence on cardiac function. |
2023-12-19 |
2023-12-23 |
Not clear |
| Oualid Abboussi, Zmarak Ahmad Khan, Hind Ibork, Simo S Zulu, William Daniels, Khalid Taghzouti, Tim G Hale. CB2 agonist mitigates cocaine-induced reinstatement of place preference and modulates the inflammatory response in mice. Behavioural pharmacology. 2023-12-12. PMID:38085651. |
in this study, we sought to investigate the therapeutic potential of the cannabinoid cb2 receptor agonist, jwh-133, in mitigating cocaine-induced inflammation and associated motivational behavioural alterations in an in vivo model. |
2023-12-12 |
2023-12-17 |
mouse |
| Oualid Abboussi, Zmarak Ahmad Khan, Hind Ibork, Simo S Zulu, William Daniels, Khalid Taghzouti, Tim G Hale. CB2 agonist mitigates cocaine-induced reinstatement of place preference and modulates the inflammatory response in mice. Behavioural pharmacology. 2023-12-12. PMID:38085651. |
moreover, they shed light on the intricate interplay between the endocannabinoid system and cocaine-induced neurobiological changes, paving the way for potential therapeutic interventions targeting cb2 receptors in the context of cocaine addiction and associated behavioural deficits. |
2023-12-12 |
2023-12-17 |
mouse |
| Mahla Masoumi, Mohammad Amin Manavi, Razieh Mohammad Jafari, Alireza Mirzaei, Keshvad Hedayatyanfard, Mohammad Taghi Beigmohammadi, Ahmad Reza Dehpou. Cannabidiol Anticonvulsant Effects Against Lithium-Pilocarpine-Induced Status Epilepticus in Male Rats Are Mediated by Neuroinflammation Modulation and Cannabinoids 1 (CB1), But Not CB2 and GABA Cannabis and cannabinoid research. 2023-11-17. PMID:37976207. |
cannabidiol anticonvulsant effects against lithium-pilocarpine-induced status epilepticus in male rats are mediated by neuroinflammation modulation and cannabinoids 1 (cb1), but not cb2 and gaba |
2023-11-17 |
2023-11-20 |
rat |
| Marizia Trevizani, Laís Lopardi Leal, João Vitor Paes Rettore, Gilson Costa Macedo, Caio César de Souza Alves, Sandra Bertelli Ribeiro de Castro, Antônio Márcio Resende do Carmo, Silvioney Augusto da Silva, Carlos Magno da Costa Maranduba, Fernando de Sá Silv. Tumor necrosis factor α, and agonist and antagonists of cannabinoid receptor type 1 and type 2 alter the immunophenotype of stem cells from human exfoliated deciduous teeth. Einstein (Sao Paulo, Brazil). vol 21. 2023-11-16. PMID:37970951. |
to verify the involvement of the endocannabinoid system in the immunomodulatory profile of stem cells from human exfoliated deciduous teeth, in the presence or absence of tnf-α, and agonist and antagonists of cb1 and cb2. |
2023-11-16 |
2023-11-20 |
human |
| Misaki Oyama, Misaki Sakamoto, Kazuki Kitabatake, Kanami Shiina, Daisuke Kitahara, Sohei Onozawa, Keisuke Nishino, Yuka Sudo, Mitsutoshi Tsukimot. Involvement of cannabinoid receptors and adenosine A2B receptor in enhanced migration of lung cancer A549 cells induced by γ-ray irradiation. Biological & pharmaceutical bulletin. 2023-11-05. PMID:37926527. |
g-protein-coupled receptors (gpcrs) such as adenosine a2b receptor and cannabinoid receptors (cb1, cb2 and gpr55) may be involved, as they are known to have roles in proliferation, invasion, migration and tumor growth. |
2023-11-05 |
2023-11-08 |
human |