| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohamad Elbaz, Dinesh Ahirwar, Janani Ravi, Mohd W Nasser, Ramesh K Ganj. Novel role of cannabinoid receptor 2 in inhibiting EGF/EGFR and IGF-I/IGF-IR pathways in breast cancer. Oncotarget. vol 8. issue 18. 2018-03-05. PMID:27213582. |
cannabinoid receptor 2 (cnr2 or cb2) is an integral part of the endocannabinoid system. |
2018-03-05 |
2023-08-13 |
mouse |
| Teruyo Hosoya, Dai Fukumoto, Takeharu Kakiuchi, Shingo Nishiyama, Shigeyuki Yamamoto, Hiroyuki Ohba, Hideo Tsukada, Takatoshi Ueki, Kohji Sato, Yasuomi Ouch. In vivo TSPO and cannabinoid receptor type 2 availability early in post-stroke neuroinflammation in rats: a positron emission tomography study. Journal of neuroinflammation. vol 14. issue 1. 2018-03-02. PMID:28356120. |
upregulated levels of 18-kda translocator proteins (tspo) and type 2 endocannabinoid receptors (cb2) are considered to reflect different aspects of microglia-related neuroinflammatory responses in the brain. |
2018-03-02 |
2023-08-13 |
rat |
| Olga Seleverstov, Ana Tobiasz, J Scott Jackson, Ryan Sullivan, Dejian Ma, J Pierce Sullivan, Steven Davison, Yada Akkhawattanangkul, Danielle L Tate, Terry Costello, Stacey Barnett, Wei Li, Giancarlo Mari, Alex M Dopico, Anna N Bukiy. Maternal alcohol exposure during mid-pregnancy dilates fetal cerebral arteries via endocannabinoid receptors. Alcohol (Fayetteville, N.Y.). vol 61. 2018-02-27. PMID:28554529. |
in summary, alcohol exposure dilates fetal cerebral arteries via endocannabinoid receptors and results in an increased function of cb2. |
2018-02-27 |
2023-08-13 |
human |
| Attila Köfalvi, Cristina Lemos, Ana M Martín-Moreno, Bárbara S Pinheiro, Luis García-García, Miguel A Pozo, Ângela Valério-Fernandes, Rui O Beleza, Paula Agostinho, Ricardo J Rodrigues, Susana J Pasquaré, Rodrigo A Cunha, María L de Ceballo. Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:26976670. |
stimulation of brain glucose uptake by cannabinoid cb2 receptors and its therapeutic potential in alzheimer's disease. |
2018-02-22 |
2023-08-13 |
mouse |
| Attila Köfalvi, Cristina Lemos, Ana M Martín-Moreno, Bárbara S Pinheiro, Luis García-García, Miguel A Pozo, Ângela Valério-Fernandes, Rui O Beleza, Paula Agostinho, Ricardo J Rodrigues, Susana J Pasquaré, Rodrigo A Cunha, María L de Ceballo. Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:26976670. |
cannabinoid cb2 receptors (cb2rs) are emerging as important therapeutic targets in brain disorders that typically involve neurometabolic alterations. |
2018-02-22 |
2023-08-13 |
mouse |
| L N Maslov, R S Karpo. [Prospects for the Use of Cannabinoid Receptor Ligands for the Treatment of Metabolic Syndrome and Atherosclerosis: Analysis of Experimental and Clinical Data]. Vestnik Rossiiskoi akademii meditsinskikh nauk. vol 72. issue 1. 2018-02-20. PMID:29308855. |
to validate the expediency of clinical research of cb2 receptor agonists in patients with atherosclerosis the comparative analysis of antiatherogenic properties of cannabinoids should be performed. |
2018-02-20 |
2023-08-13 |
mouse |
| Ling Yang, Shaojuan Zhang, Xiaoxi Ling, Pin Shao, Ningyang Jia, Mingfeng Ba. Multilayer photodynamic therapy for highly effective and safe cancer treatment. Acta biomaterialia. vol 54. 2018-02-14. PMID:28285077. |
in this study, we target two proteins upregulated in cancers: the cannabinoid cb2 receptor (cb |
2018-02-14 |
2023-08-13 |
Not clear |
| Soumita Ghosh, Isabel González-Mariscal, Josephine M Egan, Ruin Moadde. Targeted proteomics of cannabinoid receptor CB1 and the CB1b isoform. Journal of pharmaceutical and biomedical analysis. vol 144. 2018-02-05. PMID:27914737. |
cannabinoid receptors (cbr), including cb1 and cb2 have been therapeutic targets for a number of conditions. |
2018-02-05 |
2023-08-13 |
Not clear |
| Antje Scholl, Igor Ivanov, Burkhard Hin. Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2. Oncotarget. vol 7. issue 38. 2018-01-30. PMID:27556861. |
in addition, the inhibitory effect of win 55,212-2 was not reversed by antagonists to cannabinoid receptors (cb1, cb2) or transient receptor potential vanilloid 1. |
2018-01-30 |
2023-08-13 |
human |
| Helen de Morais, Camila P de Souza, Luisa M da Silva, Daniele M Ferreira, Cristiane Hatsuko Baggio, Ana Carolina Vanvossen, Milene Cristina de Carvalho, José Eduardo da Silva-Santos, Leandro José Bertoglio, Joice M Cunha, Janaina M Zanovel. Anandamide reverses depressive-like behavior, neurochemical abnormalities and oxidative-stress parameters in streptozotocin-diabetic rats: Role of CB1 receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 10. 2018-01-29. PMID:27544303. |
for this, diabetic (dbt) male wistar rats were intraperitoneally treated with cannabinoid cb1 (am251, 1mg/kg) or cb2 (am630, 1mg/kg) receptor antagonists followed by anandamide (aea, 0.005mg/kg) and then submitted to the forced swimming test (fst). |
2018-01-29 |
2023-08-13 |
rat |
| Tyler E Gaston, Daniel Friedma. Pharmacology of cannabinoids in the treatment of epilepsy. Epilepsy & behavior : E&B. vol 70. issue Pt B. 2018-01-16. PMID:28087250. |
it has long been known that ∆9-thc has partial agonist activity at the endocannabinoid receptors cb1 and cb2, though it also binds to other targets which may modulate neuronal excitability and neuroinflammation. |
2018-01-16 |
2023-08-13 |
human |
| Hélène François, Antoine Durrbach, Séverine Beaudreuil, Bernard Charpentier, Lola Lecr. [Role of cannabinoid receptors in renal diseases]. Nephrologie & therapeutique. vol 12 Suppl 1. 2018-01-12. PMID:26968477. |
the cannabinoid system and more specifically the cannabinoid receptors 1 (cb1) and 2 (cb2) may represent a new therapeutic target in chronic kidney disease. |
2018-01-12 |
2023-08-13 |
human |
| Marta Celorrio, Diana Fernández-Suárez, Estefanía Rojo-Bustamante, Víctor Echeverry-Alzate, María J Ramírez, Cecilia J Hillard, José A López-Moreno, Rafael Maldonado, Julen Oyarzábal, Rafael Franco, María S Aymeric. Fatty acid amide hydrolase inhibition for the symptomatic relief of Parkinson's disease. Brain, behavior, and immunity. vol 57. 2018-01-11. PMID:27318096. |
the symptomatic relief of urb597 was confirmed in haloperidol-induced catalepsy assays, where its anti-cataleptic effects were both blocked by antagonists of the two cannabinoid receptors (cb1 and cb2), and abolished in animals deficient in these receptors. |
2018-01-11 |
2023-08-13 |
mouse |
| Natalia Malek, Magdalena Kostrzewa, Wioletta Makuch, Agnieszka Pajak, Mateusz Kucharczyk, Fabiana Piscitelli, Barbara Przewlocka, Vincenzo Di Marzo, Katarzyna Starowic. The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain. Pharmacological research. vol 111. 2018-01-05. PMID:27326920. |
among the possible targets of these mediators, only the mrna levels of cb2, gpr18 and gpr55, which are believed to be novel cannabinoid receptors, were upregulated in the spinal cord and/or drg of cci rats. |
2018-01-05 |
2023-08-13 |
rat |
| Elk Kossatz, Rafael Maldonado, Patricia Robled. CB2 cannabinoid receptors modulate HIF-1α and TIM-3 expression in a hypoxia-ischemia mouse model. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 12. 2018-01-05. PMID:28253997. |
cb2 cannabinoid receptors modulate hif-1α and tim-3 expression in a hypoxia-ischemia mouse model. |
2018-01-05 |
2023-08-13 |
mouse |
| Elk Kossatz, Rafael Maldonado, Patricia Robled. CB2 cannabinoid receptors modulate HIF-1α and TIM-3 expression in a hypoxia-ischemia mouse model. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 12. 2018-01-05. PMID:28253997. |
the role of cb2 cannabinoid receptors (cb |
2018-01-05 |
2023-08-13 |
mouse |
| Cristiane R de Carvalho, Alexandre A Hoeller, Pedro L C Franco, Athos P S Martini, Flávia M S Soares, Katia Lin, Rui D Prediger, Benjamin J Whalley, Roger Wal. The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazole-induced seizure severity in Wistar rats. Epilepsy research. vol 127. 2018-01-02. PMID:27608434. |
the cannabinoid cb2 receptor-specific agonist am1241 increases pentylenetetrazole-induced seizure severity in wistar rats. |
2018-01-02 |
2023-08-13 |
rat |
| Fang Gao, Ling-Hong Zhang, Tang-Feng Su, Lin Li, Rui Zhou, Miao Peng, Cai-Hua Wu, Xiao-Cui Yuan, Ning Sun, Xian-Fang Meng, Bo Tian, Jing Shi, Hui-Lin Pan, Man L. Signaling Mechanism of Cannabinoid Receptor-2 Activation-Induced β-Endorphin Release. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26108183. |
activation of cannabinoid receptor-2 (cb2) results in β-endorphin release from keratinocytes, which then acts on primary afferent neurons to inhibit nociception. |
2017-12-29 |
2023-08-13 |
rat |
| Renata Androvicova, Jiri Horacek, Tibor Stark, Filippo Drago, Vincenzo Mical. Endocannabinoid system in sexual motivational processes: Is it a novel therapeutic horizon? Pharmacological research. vol 115. 2017-12-27. PMID:27884725. |
the endocannabinoid system (ecs), which is composed of the cannabinoid receptors types 1 and 2 (cb1 and cb2) for marijuana's psychoactive ingredient Δ |
2017-12-27 |
2023-08-13 |
Not clear |
| Cristina Palomo-Garo, Yolanda Gómez-Gálvez, Concepción García, Javier Fernández-Rui. Targeting the cannabinoid CB2 receptor to attenuate the progression of motor deficits in LRRK2-transgenic mice. Pharmacological research. vol 110. 2017-12-21. PMID:27063942. |
targeting the cannabinoid cb2 receptor to attenuate the progression of motor deficits in lrrk2-transgenic mice. |
2017-12-21 |
2023-08-13 |
mouse |