| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Grazia Cascio, Pietro Marini, Roger G Pertwe. The Displacement Binding Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells. Methods in molecular biology (Clifton, N.J.). vol 1412. 2017-12-07. PMID:27245891. |
here, we describe the displacement binding assay that is carried out with a radioligand and cho (chinese hamster ovarian) cells stably transfected with the human cannabinoid cb2 receptor. |
2017-12-07 |
2023-08-13 |
human |
| Pietro Marini, Maria Grazia Cascio, Roger G Pertwe. The Cyclic AMP Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells. Methods in molecular biology (Clifton, N.J.). vol 1412. 2017-12-07. PMID:27245894. |
the cyclic amp assay using human cannabinoid cb2 receptor-transfected cells. |
2017-12-07 |
2023-08-13 |
human |
| Pietro Marini, Maria Grazia Cascio, Roger G Pertwe. The Cyclic AMP Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells. Methods in molecular biology (Clifton, N.J.). vol 1412. 2017-12-07. PMID:27245894. |
here, we describe the cyclic amp assay that is carried out with commercially available non-radioligand ready-to-use kits and chinese hamster ovarian (cho) cells stably transfected with the human cannabinoid cb2 receptor. |
2017-12-07 |
2023-08-13 |
human |
| Marjolein Soethoudt, Noortje van Gils, Mario van der Stelt, Laura H Heitma. Protocol to Study β-Arrestin Recruitment by CB1 and CB2 Cannabinoid Receptors. Methods in molecular biology (Clifton, N.J.). vol 1412. 2017-12-07. PMID:27245896. |
protocol to study β-arrestin recruitment by cb1 and cb2 cannabinoid receptors. |
2017-12-07 |
2023-08-13 |
human |
| Marjolein Soethoudt, Noortje van Gils, Mario van der Stelt, Laura H Heitma. Protocol to Study β-Arrestin Recruitment by CB1 and CB2 Cannabinoid Receptors. Methods in molecular biology (Clifton, N.J.). vol 1412. 2017-12-07. PMID:27245896. |
cannabinoid cb1 and cb2 receptors are g-protein-coupled receptors (gpcrs) that recruit β-arrestins upon activation by (partial) agonists. |
2017-12-07 |
2023-08-13 |
human |
| Tiziana Bisogn. Assay of DAGLα/β Activity. Methods in molecular biology (Clifton, N.J.). vol 1412. 2017-12-07. PMID:27245901. |
the endocannabinoid 2-arachidonoylglycerol (2-ag) exerts its physiological action by binding to and functionally activating type-1 (cb1) and type-2 (cb2) cannabinoid receptors. |
2017-12-07 |
2023-08-13 |
Not clear |
| Shalley N Kudalkar, Philip J Kingsley, Lawrence J Marnet. Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. Methods in molecular biology (Clifton, N.J.). vol 1412. 2017-12-07. PMID:27245906. |
the endocannabinoids, 2-arachidonoylglycerol (2-ag) and arachidonylethanolamide (aea), are endogenous ligands for the cannabinoid receptors (cb1 and cb2) and are implicated in a wide array of physiological processes. |
2017-12-07 |
2023-08-13 |
Not clear |
| R B Frei, P Luschnig, G P Parzmair, M Peinhaupt, S Schranz, A Fauland, C E Wheelock, A Heinemann, E M Stur. Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice. Allergy. vol 71. issue 7. 2017-11-21. PMID:26850094. |
the endocannabinoid 2-arachidonoylglycerol (2-ag) has been proposed to elicit eosinophil migration in a cb2 receptor/gi/o -dependent manner. |
2017-11-21 |
2023-08-13 |
mouse |
| Young C Chung, Won-Ho Shin, Jeong Y Baek, Eun J Cho, Hyung H Baik, Sang R Kim, So-Yoon Won, Byung K Ji. CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson's disease. Experimental & molecular medicine. vol 48. issue 1. 2017-11-20. PMID:27534533. |
the cannabinoid (cb2) receptor type 2 has been proposed to prevent the degeneration of dopamine neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-treated mice. |
2017-11-20 |
2023-08-13 |
mouse |
| Elif Bilgic, Elif Guzel, Sevil Kose, Makbule Cisel Aydin, Eda Karaismailoglu, Irem Akar, Alp Usubutun, Petek Korkusu. Endocannabinoids modulate apoptosis in endometriosis and adenomyosis. Acta histochemica. vol 119. issue 5. 2017-11-16. PMID:28549792. |
endocannabinoid receptors cb1 and cb2, their synthesizing and catabolizing enzymes (faah, nape-pld, dagl, magl) and the apoptotic indexes were immunohistochemically assessed in endometriotic and adenomyotic tissues. |
2017-11-16 |
2023-08-13 |
Not clear |
| Leonid N Maslov, Igor Khaliulin, Yi Zhang, Andrey V Krylatov, Natalia V Naryzhnaya, Raphael Mechoulam, Luciano De Petrocellis, James M Downe. Prospects for Creation of Cardioprotective Drugs Based on Cannabinoid Receptor Agonists. Journal of cardiovascular pharmacology and therapeutics. vol 21. issue 3. 2017-11-02. PMID:26487546. |
cannabinoids inhibit na(+)/ca(2+)exchange via peripheral cannabinoid receptor (cb2) activation that may also be related to the antiapoptotic and cardioprotective effects of cannabinoids. |
2017-11-02 |
2023-08-13 |
Not clear |
| A P López-Cardona, M J Sánchez-Calabuig, P Beltran-Breña, N Agirregoitia, D Rizos, E Agirregoitia, A Gutierrez-Adá. Exocannabinoids effect on in vitro bovine oocyte maturation via activation of AKT and ERK1/2. Reproduction (Cambridge, England). vol 152. issue 6. 2017-10-31. PMID:27798282. |
through rt-pcr and immunocytochemistry, this study confirms the presence of cb1 and cb2 cannabinoid receptors in bovine oocytes and shows how exposure to the exogenous cannabinoids hu-210 and thc during their in vitro maturation (ivm) activates the phosphorylation of akt and erk1/2 proteins associated with the resumption of meiosis. |
2017-10-31 |
2023-08-13 |
cattle |
| Fernando Correa, Manuel L Wolfson, Paula Valchi, Julieta Aisemberg, Ana María Franch. Endocannabinoid system and pregnancy. Reproduction (Cambridge, England). vol 152. issue 6. 2017-10-31. PMID:27798285. |
the endocannabinoid system (ecs), is a complex system, comprising the main endogenous ligands anandamide and 2-arachidonoyl glycerol, the cannabinoid receptors cb1 and cb2 and the biosynthetic and degrading enzymes. |
2017-10-31 |
2023-08-13 |
human |
| M Almada, C Amaral, M Diniz-da-Costa, G Correia-da-Silva, N A Teixeira, B M Fonsec. The endocannabinoid anandamide impairs in vitro decidualization of human cells. Reproduction (Cambridge, England). vol 152. issue 4. 2017-10-30. PMID:27568210. |
endocannabinoids (ecbs) are endogenous mediators that along with the cannabinoid receptors (cb1 and cb2), a membrane transporter and metabolic enzymes form the endocannabinoid system (ecs). |
2017-10-30 |
2023-08-13 |
human |
| Kathryn J Argue, Jonathan W VanRyzin, David J Falvo, Allison R Whitaker, Stacey J Yu, Margaret M McCarth. Activation of Both CB1 and CB2 Endocannabinoid Receptors Is Critical for Masculinization of the Developing Medial Amygdala and Juvenile Social Play Behavior. eNeuro. vol 4. issue 1. 2017-10-30. PMID:28144625. |
activation of both cb1 and cb2 endocannabinoid receptors is critical for masculinization of the developing medial amygdala and juvenile social play behavior. |
2017-10-30 |
2023-08-13 |
rat |
| Kathryn J Argue, Jonathan W VanRyzin, David J Falvo, Allison R Whitaker, Stacey J Yu, Margaret M McCarth. Activation of Both CB1 and CB2 Endocannabinoid Receptors Is Critical for Masculinization of the Developing Medial Amygdala and Juvenile Social Play Behavior. eNeuro. vol 4. issue 1. 2017-10-30. PMID:28144625. |
here we use specific drugs to target signaling through either the cb1 or cb2 endocannabinoid receptor (cb1r or cb2r) to determine which modulates the development of sex differences in play. |
2017-10-30 |
2023-08-13 |
rat |
| Erhei Dai, Lianshan Zhang, Lihong Ye, Shiqing Wan, Lulu Feng, Qi Qi, Fang Yao, Zhen L. Hepatic expression of cannabinoid receptors CB1 and CB2 correlate with fibrogenesis in patients with chronic hepatitis B. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. vol 59. 2017-10-25. PMID:28315398. |
hepatic expression of cannabinoid receptors cb1 and cb2 correlate with fibrogenesis in patients with chronic hepatitis b. |
2017-10-25 |
2023-08-13 |
Not clear |
| Saoirse Elizabeth O'Sulliva. An update on PPAR activation by cannabinoids. British journal of pharmacology. vol 173. issue 12. 2017-10-23. PMID:27077495. |
activation of all isoforms, but primarily pparα and γ, mediates some (but not all) of the analgesic, neuroprotective, neuronal function modulation, anti-inflammatory, metabolic, anti-tumour, gastrointestinal and cardiovascular effects of some cannabinoids, often in conjunction with activation of the more traditional target sites of action such as the cannabinoid cb1 and cb2 receptors and the trpv1 ion channel. |
2017-10-23 |
2023-08-13 |
Not clear |
| Chou-Ming Yeh, Ting Ruan, Yu-Jung Lin, Tien-Huan Hs. Activation of cannabinoid CB1 receptors suppresses the ROS-induced hypersensitivity of rat vagal lung C-fiber afferents. Pulmonary pharmacology & therapeutics. vol 40. 2017-10-23. PMID:27328978. |
cannabinoids (cbs) exert antinociceptive effects by binding to specific cb receptors, designated cb1 and cb2 (type 2) for type 1 and type 2, respectively. |
2017-10-23 |
2023-08-13 |
rat |
| Z Malik, L Bayman, J Valestin, A Rizvi-Toner, S Hashmi, R Sche. Dronabinol increases pain threshold in patients with functional chest pain: a pilot double-blind placebo-controlled trial. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. vol 30. issue 2. 2017-10-20. PMID:26822791. |
cannabinoid receptors 1 (cb1) and 2 (cb2) modulate release of neurotransmitters; cb1 is located in the esophageal epithelium and reduces excitatory enteric transmission and potentially could reduce esophageal hypersensitivity. |
2017-10-20 |
2023-08-13 |
human |